GerardJOakleyIIIMD

PubMed

• 19 citations
  A randomized, placebo-controlled clinical trial of bamlanivimab and etesevimab together in high-risk ambulatory patients with COVID-19 and validation of the prognostic...
  Michael Dougan, Masoud Azizad, Bharat Mocherla, Robert L. Gottlieb, Peter Chen, Corey Hebert, Russell Perry, Joseph Boscia, Barry Heller, Jason Morris, Chad Crystal, A...> ;Clinical Infectious Diseases. 2021 Oct 28
• Olaratumab-induced Biomarker Modulation in Sarcomas—Response
  Javier Martin-Broto, Patrick M Peterson, Gerard J. Oakley, Matteo Ceccarelli, Robin L. Jones> ;Molecular Cancer Therapeutics. 2021 Oct 1
• 403 citations
  Bamlanivimab plus Etesevimab in Mild or Moderate Covid-19.
  Michael Dougan, Ajay Nirula, Masoud Azizad, Bharat Mocherla, Robert L. Gottlieb, Peter Chen, Corey Hebert, Russell Perry, Joseph Boscia, Barry Heller, Jason Morris, Ch...> ;The New England Journal of Medicine. 2021 Jul 14
• 3 citations
  Analytical Accuracy of RET Fusion Detection by Break-Apart Fluorescence In Situ Hybridization.
  Jessica A. Roseberry Baker, Anthony N. Sireci, Narasimha Marella, Holly Kay Cannon, Tyler J Marquart, Timothy R. Holzer, Leslie O'Neill Reising, Joel D. Cook, Sameera ...> ;Archives of Pathology & Laboratory Medicine. 2021 Jul 7
• 19 citations
  A phase 1b study of the Notch inhibitor crenigacestat (LY3039478) in combination with other anticancer target agents (taladegib, LY3023414, or abemaciclib) in patients...
  Analia Azaro, Christophe Massard, William D. Tap, Philippe A. Cassier, Jaime R. Merchan, Antoine Italiano, Bailey Anderson, Eunice Yuen, Danni Yu, Gerard J. Oakley, Ka...> ;Investigational New Drugs. 2021 Mar 8
• 24 citations
  Phase 1 study to evaluate Crenigacestat (LY3039478) in combination with dexamethasone in patients with T-cell acute lymphoblastic leukemia and lymphoma
  Gautam Borthakur, Giovanni Martinelli, Emmanuel Raffoux, Patrice Chevallier, Jörg Chromik, Andrew Lithio, Claire Smith, Eunice Yuen, Gerard J. Oakley, Karim A. Benhadj...> ;Cancer. 2021 Feb 1
• 642 citations
  Effect of Bamlanivimab as Monotherapy or in Combination With Etesevimab on Viral Load in Patients With Mild to Moderate COVID-19: A Randomized Clinical Trial.
  Robert L. Gottlieb, Ajay Nirula, Peter Chen, Joseph Boscia, Barry Heller, Jason Morris, Gregory D. Huhn, Jose Cardona, Bharat Mocherla, Valentina Stosor, Imad Shawa, P...> ;JAMA. 2021 Feb 16
• 829 citations
  SARS-CoV-2 Neutralizing Antibody LY-CoV555 in Outpatients with Covid-19.
  Peter Chen, Ajay Nirula, Barry Heller, Robert L. Gottlieb, Joseph Boscia, Jason Morris, Gregory D. Huhn, Jose Cardona, Bharat Mocherla, Valentina Stosor, Imad Shawa, A...> ;The New England Journal of Medicine. 2021 Jan 21
• 6 citations
  Circulating Tumor Cells and Biomarker Modulation with Olaratumab Monotherapy Followed by Olaratumab plus Doxorubicin: Phase Ib Study in Patients with Soft-Tissue Sarcoma.
  Javier Martin-Broto, Antonio López Pousa, Andrew S. Brohl, Brian A. Van Tine, Benjamin C. Powers, Silvia Stacchiotti, Jean-Yves Blay, James S. Hu, Gerard J. Oakley, Ho...> ;Molecular Cancer Therapeutics. 2021 Jan 1
• 32 citations
  A randomized phase III study of abemaciclib versus erlotinib in patients with stage IV non-small cell lung cancer with a detectable KRAS mutation who failed prior plat...
  Jonathan W. Goldman, Julien Mazieres, Fabrice Barlesi, Konstantin H. Dragnev, Marianna Koczywas, Tuncay Göskel, Alexis B. Cortot, Nicolas Girard, C. Wesseler, Helge Bi...> ;Frontiers in Oncology. 2020 Oct 26
• 10 citations
  Phase 1 study of 2 high dose intensity schedules of the pan-Notch inhibitor crenigacestat (LY3039478) in combination with prednisone in patients with advanced or metas...
  Analia Azaro, Capucine Baldini, Jordi Rodon, Jean-Charles Soria, Eunice Yuen, Andrew Lithio, Gerard J. Oakley, Karim A. Benhadji, Christophe Massard> ;Investigational New Drugs. 2021 Feb 1
• 85 citations
  The genomic landscape of intrinsic and acquired resistance to cyclin-dependent kinase 4/6 inhibitors in patients with hormone receptor–positive metastatic breast cancer
  Seth A. Wander, Ofir Cohen, Xueqian Gong, Gabriela N. Johnson, Jorge E. Buendia-Buendia, Maxwell R. Lloyd, Dewey Kim, Flora Luo, Pingping Mao, Karla Helvie, Kailey J. ...> ;Cancer Discovery. 2020 May 13
• 39 citations
  Safety and clinical activity of the Notch inhibitor, crenigacestat (LY3039478), in an open-label phase I trial expansion cohort of advanced or metastatic adenoid cysti...
  Caroline Even, Ulrik Lassen, Jaime R. Merchan, C. Le Tourneau, J-C. Soria, Charles Ferté, Francesco Ricci, J. T. Diener, Eunice Yuen, Claire Smith, Gerard J. Oakley, K...> ;Investigational New Drugs. 2020 Apr 1
• 11 citations
  Single cell correlation analysis of liquid and solid biopsies in metastatic colorectal cancer.
  Anna S. Gerdtsson, Jana-Aletta Thiele, Stephanie N. Shishido, Serena Zheng, Randolph Schaffer, Kelly Bethel, Steven A. Curley, Heinz-Josef Lenz, Diana L. Hanna, Jorge ...> ;Oncotarget. 2019 Dec 17
• 6 citations
  Phase 1 study of olaratumab plus doxorubicin in Japanese patients with advanced soft-tissue sarcoma.
  Kan Yonemori, Makoto Kodaira, Taroh Satoh, Toshihiro Kudo, Shunji Takahashi, Kenji Nakano, Yuichi Ando, Tomoya Shimokata, Joji Mori, Koichi Inoue, Gerard J. Oakley, Sa...> ;Cancer Science. 2018 Dec 1
• 96 citations
  First-in-human study of LY3039478, an oral Notch signaling inhibitor in advanced or metastatic cancer.
  Christophe Massard, Analia Azaro, Jean-Charles Soria, Ulrik Lassen, C. Le Tourneau, Debashis Sarker, Claire Smith, Ute Ohnmacht, Gerard J. Oakley, Bharvin K. R. Patel,...> ;Annals of Oncology. 2018 Sep 1
• 18 citations
  "Simple Mucinous Cyst" of the Pancreas: A Clinicopathologic Analysis of 39 Examples of a Diagnostically Challenging Entity Distinct From Intraductal Papillary Mucinous...
  Alyssa M. Krasinskas, Gerard J. Oakley, Pelin Bagci, Kee-Taek Jang, Shih Fan Kuan, Michelle D. Reid, Ipek Erbarut, Volkan Adsay> ;The American Journal of Surgical Pathology. 2017 Jan 1
• 2 citations
  Same difference: A pilot study of cyclin D1, bcl-2, AMACR, and ALDH-1 identifies significant differences in expression between primary colon adenocarcinoma and its met...
  Gerard J. Oakley, Krista L. Denning, Vincent Graffeo, Doreen Griswold, Adam R. Davis, Linda G. Brown> ;Pathology, Research and Practice. 2016 Nov 1
• 15 citations
  Chemo-Predictive Assay for Targeting Cancer Stem-Like Cells in Patients Affected by Brain Tumors
  Sarah E Mathis, Anthony Alberico, Rounak Nande, Walter Neto, Logan Lawrence, Danielle R. McCallister, James Denvir, Gerrit A. Kimmey, Mark Jeffrey Mogul, Gerard J. Oak...> ;Plos One. 2014 Aug 21
• A novel mutation in the succinate dehydrogenase subunit D gene in siblings with the hereditary paraganglioma–pheochromocytoma syndrome
  Chaithra Prasad, Gerard J. Oakley, Linwah Yip, Christopher Coyne, Balasubramanya Rangaswamy, Sanjay B Dixit> ;SAGE Open Medical Case Reports. 2014 Jan 1
• 12 citations
  Higher dosage of the epidermal growth factor receptor mutant allele in lung adenocarcinoma correlates with younger age, stage IV at presentation, and poorer survival.
  Gerard J. Oakley, Simion I. Chiosea> ;Journal of Thoracic Oncology. 2011 Aug 1
• 52 citations
  The Prognostic Value of Ki-67, p53, Epidermal Growth Factor Receptor, 1p36, 9p21, 10q23, and 17p13 in Skull Base Chordomas
  Craig Horbinski, Gerard J. Oakley, Kathleen Cieply, Geeta S. Mantha, Marina N. Nikiforova, Sanja Dacic, Raja R. Seethala> ;Archives of Pathology & Laboratory Medicine. 2010 Aug 1
• 13 citations
  Vascular wall invasion in neurofibromatosis-induced aortic rupture.
  John L. Falcone, Michael R. Go, Donald T. Baril, Gerard J. Oakley, Michel S. Makaroun, Rabih A. Chaer> ;Vascular and Endovascular Surgery. 2010 Jan 1
• 119 citations
  Brachyury, SOX-9, and podoplanin, new markers in the skull base chordoma vs chondrosarcoma differential: a tissue microarray-based comparative analysis.
  Gerard J. Oakley, Kim Fuhrer, Raja R. Seethala> ;Modern Pathology. 2008 Sep 26
• 15 citations
  Diffuse Filiform Polyposis With Unique Histology Mimicking Familial Adenomatous Polyposis in a Patient Without Inflammatory Bowel Disease
  Gerard J. Oakley, Wolfgang H. Schraut, Robert L. Peel, Alyssa M. Krasinskas> ;Archives of Pathology & Laboratory Medicine. 2007 Dec 1
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