GinaZD'AmatoMD

Hematologic Oncology, Sarcoma

Associate Professor of Medicine Sarcoma Medical Oncology Assistant Director of Clinical Research Medical Director of Comprehensive Treatment Unit Sylvester Comprehensive Cancer Center/University of Miami Health System

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Office
Sylvester Comprehensive Cancer Center/University of Miami Health System
1120 NW 14th St Suite 610
Miami, FL 33136
Phone+1 305-243-2581

Fax+1 305-243-9161
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Education & Training

University of South Florida MorsaniFellowship, Hematology and Medical Oncology, 2001 - 2004
University of Miami/Jackson Health SystemResidency, Internal Medicine, 1998 - 2001
University of Miami Leonard M. Miller School of MedicineClass of 1998

Certifications & Licensure

FL State Medical License 2003 - 2025
GA State Medical License 2008 - 2019

Awards, Honors, & Recognition

Atlanta Magazine: Top Doctors Castle Connolly, 2014
CMS Meaningful Use Stage 1 Certification NextGen Ambulatory EHR, NextGen Healthcare, 2013

Clinical Trials

Safety and Efficacy Study of Glufosfamide in Previously Treated Advanced Soft Tissue Sarcoma Start of enrollment: 2007 Mar 01
Completed
Phase 2
Gemcitabine Hydrochloride and Docetaxel Followed by Doxorubicin Hydrochloride or Observation in Treating Patients With High-Risk Uterine Leiomyosarcoma Previously Removed by Surgery Start of enrollment: 2012 Jun 04
Terminated
Phase 3
Phase 3 Study to Treat Patients With Soft Tissue Sarcomas Start of enrollment: 2014 Jan 01
Completed
Phase 3
A Study of Doxorubicin Plus Olaratumab (LY3012207) in Participants With Advanced or Metastatic Soft Tissue Sarcoma Start of enrollment: 2015 Sep 14
Active, not recruiting
Phase 3
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Publications & Presentations

PubMed

18 citations
Clinical Benefit of Ripretinib Dose Escalation After Disease Progression in Advanced Gastrointestinal Stromal Tumor: An Analysis of the INVICTUS Study.
John Zalcberg, Michael Heinrich, Suzanne George, Sebastian Bauer, Patrick Schöffski, César Serrano, Hans Gelderblom, Robin L. Jones, Steven Attia, Gina Z. D'Amato, Pin...> ;The Oncologist. 2021 Nov 1
26 citations
Genomic Landscape of Angiosarcoma: A Targeted and Immunotherapy Biomarker Analysis.
Andrea P. Espejo-Freire, Andrew Elliott, Andrew E. Rosenberg, Philippos Apolinario Costa, Priscila Barreto-Coelho, Emily Jonczak, Gina Z. D'Amato, Ty K. Subhawong, Jun...> ;Cancers. 2021 Sep 26
15 citations
Clinical Activity of Ripretinib in Patients with Advanced Gastrointestinal Stromal Tumor Harboring Heterogeneous KIT/PDGFRA Mutations in the Phase III INVICTUS Study.
Sebastian Bauer, Michael Heinrich, Suzanne George, John Zalcberg, César Serrano, Hans Gelderblom, Robin L. Jones, Steven Attia, Gina Z. D'Amato, Ping Chi, Peter Reicha...> ;Clinical Cancer Research. 2021 Sep 9
3 citations
A nonrandom association of breast implants and the formation of desmoid tumors.
Philippos Apolinario Costa, Staci J. Marbin, Bruna Menon Loureiro Apolinario Costa, Andrea P. Espejo-Freire, Eduardo Edelman Saul, Priscila Barreto-Coelho, Ahkeel Alle...> ;The Breast Journal. 2021 Aug 27
5 citations
Clinical Outcomes for Primary and Radiation-Associated Angiosarcoma of the Breast with Multimodal Treatment: Long-Term Survival Is Achievable.
Joshua P. Kronenfeld, Jessica S. Crystal, Emily L. Ryon, Sina Yadegarynia, Celeste Chitters, Raphael Yechieli, Gina Z. D'Amato, Andrew E. Rosenberg, Susan B. Kesmodel,...> ;Cancers. 2021 Jul 29
170 citations
Ripretinib in patients with advanced gastrointestinal stromal tumours (INVICTUS): a double-blind, randomised, placebo-controlled, phase 3 trial.
Jean-Yves Blay, César Serrano, Michael Heinrich, John Zalcberg, Sebastian Bauer, Hans Gelderblom, Patrick Schöffski, Robin L. Jones, Steven Attia, Gina Z. D'Amato, Pin...> ;The Lancet. Oncology. 2020 Jul 1
43 citations
Overall survival and histology‐specific subgroup analyses from a phase 3, randomized controlled study of trabectedin or dacarbazine in patients with advanced liposarco...
Shreyaskumar Patel, Margaret von Mehren, Damon R. Reed, Pamela E. Kaiser, John A. Charlson, Christopher W. Ryan, Daniel A. Rushing, Michael B. Livingston, Arun S. Sing...> ;Cancer. 2019 Aug 1
22 citations
Association of Dasatinib With Progression-Free Survival Among Patients With Advanced Gastrointestinal Stromal Tumors Resistant to Imatinib.
Scott M. Schuetze, Vanessa Bolejack, Dafydd G. Thomas, Margaret von Mehren, Shreyaskumar Patel, Brian L. Samuels, Edwin Choy, Gina Z. D'Amato, Arthur P. Staddon, Krist...> ;JAMA Oncology. 2018 Jun 1
74 citations
Phase 2 study of dasatinib in patients with alveolar soft part sarcoma, chondrosarcoma, chordoma, epithelioid sarcoma, or solitary fibrous tumor.
Scott M. Schuetze, Vanessa Bolejack, Edwin Choy, Kristen N. Ganjoo, Arthur P. Staddon, Warren Chow, Hussein Abdul-Hassan Tawbi, Brian L. Samuels, Shreyaskumar Patel, M...> ;Cancer. 2017 Jan 1
192 citations
Phase II Study of the Mammalian Target of Rapamycin Inhibitor Ridaforolimus in Patients With Advanced Bone and Soft Tissue Sarcomas
Sant P. Chawla, Arthur P. Staddon, Laurence H. Baker, Scott M. Schuetze, Anthony W. Tolcher, Gina Z. D'Amato, Jean-Yves Blay, Monica M. Mita, Kamalesh Kumar Sankhala, ...> ;Journal of Clinical Oncology. 2012 Jan 1
91 citations
Phase II study of sunitinib malate, a multitargeted tyrosine kinase inhibitor in patients with relapsed or refractory soft tissue sarcomas. Focus on three prevalent hi...
S. Tariq Mahmood, Samuel V. Agresta, Carlos E. Vigil, Xiuhua Zhao, Gang Han, Gina Z. D'Amato, Ciara E. Calitri, Michelle Dean, Christopher R. Garrett, Michael J. Schel...> ;International Journal of Cancer. 2011 Oct 15
109 citations
Sunitinib treatment in pediatric patients with advanced GIST following failure of imatinib.
Katherine A. Janeway, Karen Albritton, Annick D. Van den Abbeele, Gina Z. D'Amato, Paolo Pedrazzoli, Salvatore Siena, Joel Picus, James E. Butrynski, Marcus Schlemmer,...> ;Pediatric Blood & Cancer. 2009 Jul 1
Phase II study of sunitinib malate (SM) in subjects with metastatic and/or surgically unresectable non-GIST soft tissue sarcomas.
Vigil CE, Chiappori AA, Williams CA, Shrager HH, Murray BL, Letson DG, Sullivan DM, Garrett CR, D'Amato GZ, Agresta SV> ;J. Clin. Oncol.. 2008-05-20
Preliminary efficacy and safety results of glufosfamide (GLU) in relapsed soft tissue sarcoma: Results of a phase II trial.
D'Amato GZ, Verschraegen CF, Cranmer LD, Ganjoo KN, Rosen G, Adkins DR, Mendelson DS, Langmuir VK, Kroll S> ;J. Clin. Oncol.. 2008-05-20
23 citations
Therapeutic potential of directed tyrosine kinase inhibitor therapy in sarcomas.
Audrey C Shor, Samuel V. Agresta, Gina Z. D'Amato, Vernon K. Sondak> ;Cancer Control. 2008 Jan 1
Sunitinib treatment of pediatric metastatic GIST after failure of imatinib.
Janeway KA, Matthews DC, Butrynski JE, D'Amato GZ, Agresta S, Garrett C, Corless CL, Albritton KH, Demetri GD> ;J. Clin. Oncol.. 2006-06-20
Updated results of a phase II trial of AP23573, a novel mTOR inhibitor, in patients (pts) with advanced soft tissue or bone sarcomas.
Chawla SP, Tolcher AW, Staddon AP, Schuetze SM, D'Amato GZ, Blay JY, Sankhala KK, Daly ST, Rivera VM, Demetri GD> ;J. Clin. Oncol.. 2006-06-20
The effect of the proteosome inhibitor, PS 341 on leiomyosarcoma cells.
D'Amato GZ, Windham TC, Keschman EA, Mohapatra S, Burns AC, Muro-Cacho C, Jove R, Sullivan D, Letson GD, Pledger WJ> ;J. Clin. Oncol.. 2005-06-01
83 citations
Update on the biology and therapy of gastrointestinal stromal tumors.
Gina Z. D'Amato, Dejka M. Steinert, John C. McAuliffe, Jonathan C. Trent> ;Cancer Control. 2005 Jan 1
The effect of the PI3K/AKT pathway inhibition on leiomyosarcoma cells.
D'Amato GZ, Mohapatra S, Jove R, Windham TC, Burns AC, Sullivan D, Muro-Cacho C, Letson GD, Pledger WJ> ;J. Clin. Oncol.. 2004-07-15
26 citations
Neutropenic enterocolitis (typhilitis) associated with docetaxel therapy in a patient with non-small-cell lung cancer: case report and review of literature.
Gina Z. D'Amato, Caio Max S. Rocha Lima, J.J Mahany, Carlos A. Muro-Cacho, Eric B. Haura> ;Lung Cancer. 2004 Jun 1
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