GonzaloLajeMD

PubMed

• Lithium response in bipolar disorder is associated with focal adhesion and PI3K-Akt networks: a multi-omics replication study.
  Anna H Ou, Sara B Rosenthal, Mazda Adli, Kazufumi Akiyama, Nirmala Akula, Martin Alda, Azmeraw T Amare, Raffaella Ardau, Bárbara Arias, Jean-Michel Aubry, Lena Backlun...> ;Translational Psychiatry. 2024 Feb 23
• Exploring the genetics of lithium response in bipolar disorders.
  Herrera-Rivero, M., Adli, M., Akiyama, K., Akula, N., Amare, A., Ardau, R., Arias, B., Aubry, J., Backlund, L., Bellivier, F., Benabarre, A., Bengesser, S., Bhattachar...> ;Research Square. 2023 Dec 2
• Treatment of US Children With Attention-Deficit/Hyperactivity Disorder in the Adolescent Brain Cognitive Development Study.
  Mark Olfson, Melanie M Wall, Shuai Wang, Gonzalo Laje, Carlos Blanco> ;JAMA Network Open. 2023 Apr 3
• Correction: Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients.
  Klaus Oliver Schubert, Anbupalam Thalamuthu, Azmeraw T Amare, Joseph Frank, Fabian Streit, Mazda Adl, Nirmala Akula, Kazufumi Akiyama, Raffaella Ardau, Bárbara Arias, ...> ;Translational Psychiatry. 2022 Jul 11
• 22 citations
  Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients.
  Klaus Oliver Schubert, Anbupalam Thalamuthu, Azmeraw T. Amare, Joseph Frank, Fabian Streit, Mazda Adl, Nirmala Akula, Kazufumi Akiyama, Raffaella Ardau, Bárbara Arias,...> ;Translational Psychiatry. 2021 Nov 29
• 7 citations
  Citalopram-induced pathways regulation and tentative treatment-outcome-predicting biomarkers in lymphoblastoid cell lines from depression patients.
  Abdul Karim Barakat, Catharina Scholl, Michael Steffens, Kerstin Brandenburg, Marcus Ising, Susanne Lucae, Florian Holsboer, Gonzalo Laje, Ganna V. Kalayda, Ulrich Jae...> ;Translational Psychiatry. 2020 Jul 1
• 51 citations
  Association of polygenic score for major depression with response to lithium in patients with bipolar disorder
  Azmeraw T. Amare, Klaus Oliver Schubert, Liping Hou, Scott R. Clark, Sergi Papiol, Micah Cearns, Urs Heilbronner, Franziska Degenhardt, Fasil Tekola-Ayele, Yi-Hsiang H...> ;Molecular Psychiatry. 2021 Mar 16
• 15 citations
  Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study
  Janos Kalman, Sergi Papiol, Andreas J. Forstner, Urs Heilbronner, Franziska Degenhardt, Jana Strohmaier, Mazda Adli, Kristina Adorjan, Nirmala Akula, Martin Alda, Heik...> ;Bipolar Disorders. 2019 Feb 1
• Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Associati...
  Amare, A. T.,Schubert, K. O.,Hou, L.,Clark, S. R.,Papiol, S.,Heilbronner, U.,Degenhardt, F.,Tekola-Ayele, F.,Hsu, Y. H.,Shekhtman, T.,Adli, M.,Akula, N.,Akiyama, K.,Ar...> ;JAMA Psychiatry. 2017 Nov 10
• 16 citations
  Gene expression and proliferation biomarkers for antidepressant treatment resistance.
  Jörg Breitfeld, Catharina Scholl, Michael Steffens, Gonzalo Laje, Julia C. Stingl> ;Translational Psychiatry. 2017 Mar 14
• Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder.
  Hou, L.,Bergen, S. E.,Akula, N.,Song, J.,Hultman, C. M.,Landén, M.,Adli, M.,Alda, M.,Ardau, R.,Arias, B.,Aubry, J. M.,Backlund, L.,Badner, J. A.,Barrett, T. B.,Bauer, ...> ;Hum. Mol. Genet.. 2016 Jun 23
• Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study.
  Hou L, Heilbronner U, Degenhardt F, Adli M, Akiyama K, Akula N, Ardau R, Arias B, Backlund L, Banzato CEM, Benabarre A, Bengesser S, Bhattacharjee AK, Biernacka JM, Bi...> ;Lancet. 2016-03-12
• A pilot study of plasma metabolomic patterns from patients treated with ketamine for bipolar depression: evidence for a response-related difference in mitochondrial ne...
  Villaseñor, A.,Ramamoorthy, A.,Silva Dos Santos, M.,Lorenzo, M. P.,Laje, G.,Zarate, C.,Barbas, C.,Wainer, I. W.> ;Br. J. Pharmacol.. 2014 Apr 02
• The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data.
  Thompson, P. M.,Stein, J. L.,Medland, S. E.,Hibar, D. P.,Vasquez, A. A.,Renteria, M. E.,Toro, R.,Jahanshad, N.,Schumann, G.,Franke, B.,Wright, M. J.,Martin, N. G.,Agar...> ;Brain Imaging Behav. 2014 Jan 09
• RNA-sequencing of the brain transcriptome implicates dysregulation of neuroplasticity, circadian rhythms and GTPase binding in bipolar disorder.
  Akula, N.,Barb, J.,Jiang, X.,Wendland, J. R.,Choi, K. H.,Sen, S. K.,Hou, L.,Chen, D. T.,Laje, G.,Johnson, K.,Lipska, B. K.,Kleinman, J. E.,Corrada-Bravo, H.,Detera-Wad...> ;Mol. Psychiatry. 2014 Jan 08
• National Trends in the Mental Health Care of Children, Adolescents, and Adults by Office-Based Physicians
  Mark Olfson, Carlos Blanco, Gonzalo Laje> ;JAMA. 2013 Nov 29
• Retention and attrition among African Americans in the STAR*D study: what causes research volunteers to stay or stray?
  Murphy EJ, Kassem L, Chemerinski A, Rush AJ, Laje G, McMahon FJ> ;Depress Anxiety. 2013-11-01
• Race, Genetic Ancestry and Response to Antidepressant Treatment for Major Depression
  Gonzalo Laje, Francis J McMahon, Layla Kassem> ;Nature. 2013 Jul 5
• Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report.
  Manchia M, Adli M, Akula N, Ardau R, Aubry J, Backlund L, Banzato CE, Baune BT, Bellivier F, Bengesser S, Biernacka JM, Brichant-Petitjean C, Bui E, Calkin CV, Cheng A...> ;PLoS ONE. 2013-01-01
• Brain-Derived Neurotrophic Factor Val66Met Polymorphism and Antidepressant Efficacy of Ketamine in Depressed Patients.
  Laje, G., Lally, N., Mathews, D., Brutsche, N., Chemerinski, A., Akula, N., Kelmendi, B., Simen, A., McMahon, F. J., Sanacora, G., Zarate, C.> ;Biol Psychiatry. 2012 Dec 1
• Relationship of Ketamine's Plasma Metabolites with Response, Diagnosis, and Side Effects in Major Depression.
  Zarate, C. A., Brutsche, N., Laje, G., Luckenbaugh, D. A., Venkata, S. L., Ramamoorthy, A., Moaddel, R., Wainer, I. W.> ;Biol Psychiatry. 2012 Aug 15
• Identification of common variants associated with human hippocampal and intracranial volumes.
  Stein JL, Medland SE, Vasquez AA, Hibar DP, Senstad RE, Winkler AM, Toro R, Appel K, Bartecek R, Bergmann Ø, Bernard M, Brown AA, Cannon DM, Chakravarty MM, Christofor...> ;Nat. Genet.. 2012-04-15
• 17 citations
  Pharmacological Treatment of Disruptive Behavior in Smith-Magenis Syndrome
  Gonzalo Laje, Rebecca A. Bernert, Rebecca Morse, Maryland Pao, Ann C.M. Smith> ;American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 2010 Nov 15
• 69 citations
  Autism Spectrum Features in Smith-Magenis Syndrome
  Gonzalo Laje, Rebecca Morse, William Richter, Jonathan Ball, Maryland Pao, Ann C.M. Smith> ;American Journal of Medical Genetics. Part C, Seminars in Medical Genetics. 2010 Nov 15
• 10 citations
  Three-year medication prophylaxis in panic disorder: to continue or discontinue? A naturalistic study.
  Yujuan Choy, Eric D. Peselow, Brady G. Case, Mary Ann Pressman, Jamie A. Luff, Gonzalo Laje, Mary Paizis, Patrick Ying, Mary T. Guardino> ;Comprehensive Psychiatry. 2007 Sep 1
• Join now to see all