GopakumarVasydevaIyerMD

PubMed

• 1 citations
  First-in-human study of naporafenib (LXH254) with or without spartalizumab in adult patients with advanced solid tumors harboring MAPK signaling pathway alterations.
  Filip Janku, Tae Min Kim, Gopakumar Iyer, Anna Spreafico, Elena Elez, Maja de Jonge, Noboru Yamamoto, Anthonie J van der Wekken, Paolo Antonio Ascierto, Michela Maur, ...> ;European Journal of Cancer. 2024 Jan 1
• 1 citations
  Molecular Results and Potential Biomarkers Identified from the Phase 3 MILO/ENGOT-ov11 Study of Binimetinib versus Physician Choice of Chemotherapy in Recurrent Low-Gr...
  Rachel N Grisham, Ignace Vergote, Susana Banerjee, Esther Drill, Elsa Kalbacher, Mansoor Raza Mirza, Ignacio Romero, Peter Vuylsteke, Robert L Coleman, Felix Hilpert, ...> ;Clinical Cancer Research. 2023 Oct 13
• Bladder preservation after neoadjuvant therapy - 2021 IBCN updates part 1.
  Patrick J Hensley, Roland Seiler, Harry Herr, Kent W Mouw, Gopa Iyer, Lars Dyrskjøt, Roman Nawroth, Peter Goebell, Bernd Schmitz-Drager, Tilman Todenhofer, Peter C Bla...> ;Urologic Oncology. 2023 Jul 1
• 4 citations
  KDM6A Loss Triggers an Epigenetic Switch That Disrupts Urothelial Differentiation and Drives Cell Proliferation in Bladder Cancer.
  Hong Qiu, Vladimir Makarov, Jennifer K Bolzenius, Angela Halstead, Yvonne Parker, Allen Wang, Gopakumar V Iyer, Hannah Wise, Daniel Kim, Varna Thayaparan, Daniel J Lin...> ;Cancer Research. 2023 Mar 15
• 15 citations
  Multicenter Phase II Clinical Trial of Gemcitabine and Cisplatin as Neoadjuvant Chemotherapy for Patients With High-Grade Upper Tract Urothelial Carcinoma.
  Jonathan A Coleman, Wesley Yip, Nathan C Wong, Daniel D Sjoberg, Bernard H Bochner, Guido Dalbagni, S Machele Donat, Harry W Herr, Eugene K Cha, Timothy F Donahue, Eug...> ;Journal of Clinical Oncology. 2023 Mar 10
• 1 citations
  Author Correction: FOXA1 repression drives lineage plasticity and immune heterogeneity in bladder cancers with squamous differentiation.
  Joshua I Warrick, Wenhuo Hu, Hironobu Yamashita, Vonn Walter, Lauren Shuman, Jenna M Craig, Lan L Gellert, Mauro A A Castro, A Gordon Robertson, Fengshen Kuo, Irina Os...> ;Nature Communications. 2022 Dec 23
• 6 citations
  Genomic heterogeneity as a barrier to precision oncology in urothelial cancer.
  Timothy N Clinton, Ziyu Chen, Hannah Wise, Andrew T Lenis, Shweta Chavan, Mark T A Donoghue, Nima Almassi, Carissa E Chu, Shawn Dason, Pavitra Rao, James A Rodrigues, ...> ;Cell Reports. 2022 Dec 20
• 10 citations
  Collaborative study from the Bladder Cancer Advocacy Network for the genomic analysis of metastatic urothelial cancer.
  Jeffrey S Damrauer, Wolfgang Beckabir, Jeff Klomp, Mi Zhou, Elizabeth R Plimack, Matthew D Galsky, Petros Grivas, Noah M Hahn, Peter H O'Donnell, Gopa Iyer, David I Qu...> ;Nature Communications. 2022 Nov 4
• 9 citations
  FOXA1 repression drives lineage plasticity and immune heterogeneity in bladder cancers with squamous differentiation.
  Joshua I Warrick, Wenhuo Hu, Hironobu Yamashita, Vonn Walter, Lauren Shuman, Jenna M Craig, Lan L Gellert, Mauro A A Castro, A Gordon Robertson, Fengshen Kuo, Irina Os...> ;Nature Communications. 2022 Nov 2
• 3 citations
  Inherited Germline Cancer Susceptibility Gene Variants in Individuals with Non-Muscle-Invasive Bladder Cancer.
  Eugene J Pietzak, Karissa Whiting, Preethi Srinivasan, Chaitanya Bandlamudi, Aliya Khurram, Vijai Joseph, Aleksandra Walasek, Emily Bochner, Timothy Clinton, Nima Alma...> ;Clinical Cancer Research. 2022 Oct 3
• 4 citations
  Clinical and Genomic Characterization of Bladder Carcinomas With Glandular Phenotype.
  Nima Almassi, Karissa Whiting, Antoun Toubaji, Andrew T Lenis, Emmet J Jordan, Helen Won, Ashley M Regazzi, Ying-Bei Chen, Anuradha Gopalan, Sahussapont J Sirintrapun,...> ;JCO Precision Oncology. 2022 Jun 1
• 6 citations
  Long-term Outcomes of Local and Metastatic Small Cell Carcinoma of the Urinary Bladder and Genomic Analysis of Patients Treated With Neoadjuvant Chemotherapy.
  Min Yuen Teo, Brendan J Guercio, Arshi Arora, Xueli Hao, Ashley M Regazzi, Timothy Donahue, Harry W Herr, Alvin C Goh, Eugene K Cha, Eugene Pietzak, Sherri M Donat, Gu...> ;Clinical Genitourinary Cancer. 2022 Oct 1
• 1 citations
  Correction: Natural history, response to systemic therapy, and genomic landscape of plasmacytoid urothelial carcinoma.
  Min Yuen Teo, Hikmat Al-Ahmadie, Kenneth Seier, Christopher Tully, Ashley M Regazzi, Eugene Pietzak, David B Solit, Satish Tickoo, Victor Reuter, Eugene K Cha, Harry H...> ;British Journal of Cancer. 2022 May 1
• 25 citations
  Neoadjuvant Atezolizumab With Gemcitabine and Cisplatin in Patients With Muscle-Invasive Bladder Cancer: A Multicenter, Single-Arm, Phase II Trial.
  Samuel A Funt, Michael Lattanzi, Karissa Whiting, Hikmat Al-Ahmadie, Colleen Quinlan, Min Yuen Teo, Chung-Han Lee, David Aggen, Danielle Zimmerman, Deaglan McHugh, Arl...> ;Journal of Clinical Oncology. 2022 Apr 20
• 34 citations
  Neoantigen-specific CD8 T cell responses in the peripheral blood following PD-L1 blockade might predict therapy outcome in metastatic urothelial carcinoma.
  Jeppe Sejerø Holm, Samuel A Funt, Annie Borch, Kamilla Kjærgaard Munk, Anne-Mette Bjerregaard, James L Reading, Colleen Maher, Ashley Regazzi, Phillip Wong, Hikmat Al-...> ;Nature Communications. 2022 Apr 11
• 183 citations
  Genomic characterization of metastatic patterns from prospective clinical sequencing of 25,000 patients.
  Bastien Nguyen, Christopher Fong, Anisha Luthra, Shaleigh A Smith, Renzo G DiNatale, Subhiksha Nandakumar, Henry Walch, Walid K Chatila, Ramyasree Madupuri, Ritika Kun...> ;Cell. 2022 Feb 3
• 8 citations
  Pre-clinical activity of the oral DNA-PK inhibitor, peposertib (M3814), combined with radiation in xenograft models of cervical cancer.
  Sushmita B Gordhandas, Beryl Manning-Geist, Christina Henson, Gopa Iyer, Ginger J Gardner, Yukio Sonoda, Kathleen N Moore, Carol Aghajanian, M Herman Chui, Rachel N Gr...> ;Scientific Reports. 2022 Jan 19
• 9 citations
  Clinical and Morphologic Characteristics of Fibroblast Growth Factor Receptor Inhibitor-Associated Retinopathy.
  Jasmine H. Francis, James J. Harding, Alison M. Schram, Julia Canestraro, Dianna Haggag-Lindgren, Murk Heinemann, Anuja Kriplani, Komal Jhaveri, Martin H. Voss, Dean F...> ;JAMA Ophthalmology. 2021 Oct 1
• 48 citations
  LAG-3 expression on peripheral blood cells identifies patients with poorer outcomes after immune checkpoint blockade.
  , , , , , , , , , , , , , , , , , , , , , , > ;Science Translational Medicine. 2021 Aug 25
• 18 citations
  The Genitourinary Pathology Society Update on Classification of Variant Histologies, T1 Substaging, Molecular Taxonomy, and Immunotherapy and PD-L1 Testing Implication...
  Eva Compérat, Mahul B. Amin, Jonathan I. Epstein, Donna E. Hansel, Gladell P. Paner, Hikmat Al-Ahmadie, Larry True, DIlek Bayder, Trinity J. Bivalacqua, Fadi Brimo, Li...> ;Advances in Anatomic Pathology. 2021 Jul 1
• 19 citations
  The Genitourinary Pathology Society Update on Classification and Grading of Flat and Papillary Urothelial Neoplasia With New Reporting Recommendations and Approach to ...
  Mahul B. Amin, Eva Compérat, Jonathan I. Epstein, Lawrence D. True, Donna E. Hansel, Gladell P. Paner, Hikmat Al-Ahmadie, Dilek Ertoy Baydar, Trinity J. Bivalacqua, Fa...> ;Advances in Anatomic Pathology. 2021 Jul 1
• 52 citations
  Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS.
  A. Rose Brannon, Gowtham Jayakumaran, Monica Diosdado, Juber Patel, Anna Razumova, Yu Hu, Fanli Meng, Mohammad Haque, Justyna Sadowska, Brian J. Murphy, Tessara Baldi,...> ;Nature Communications. 2021 Jun 18
• 20 citations
  Identification of a Novel Inflamed Tumor Microenvironment Signature as a Predictive Biomarker of Bacillus Calmette-Guérin Immunotherapy in Non-Muscle-Invasive Bladder ...
  Jeffrey S. Damrauer, Kyle Roell, Markia A. Smith, Xuezheng Sun, Erin L. Kirk, Katherine A. Hoadley, Halei C. Benefield, G. Iyer, David B. Solit, Matthew I. Milowsky, W...> ;Clinical Cancer Research. 2021 Jun 11
• 3 citations
  Clinical and Morphologic Characteristics of Extracellular Signal-Regulated Kinase Inhibitor-Associated Retinopathy.
  Jasmine H. Francis, Julia Canestraro, Dianna Haggag-Lindgren, James J. Harding, Eli L. Diamond, Alexander Drilon, Bob T. Li, Gopa Iyer, Alison M. Schram, David H. Abra...> ;Ophthalmology. Retina. 2021 Jun 5
• 11 citations
  Pretreatment Eosinophil Counts in Patients With Advanced or Metastatic Urothelial Carcinoma Treated With Anti-PD-1/PD-L1 Checkpoint Inhibitors.
  Jose Mauricio Mota, Min Yuen Teo, Karissa Whiting, Han A Li, Ashely M Regazzi, Chung-Han Lee, Samuel Funt, Dean F. Bajorin, Irina Ostrovnaya, Gopa Iyer, Jonathan E. Ro...> ;Journal of Immunotherapy. 2021 Jun 3
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