GordonDouglasMcLarenMD

PubMed

• Abdominal pain and cirrhosis at diagnosis of hemochromatosis: Analysis of 219 referred probands with HFE p.C282Y homozygosity and a literature review.
  James C Barton, J Clayborn Barton, Neha Patel, Gordon D McLaren> ;Plos One. 2021 Jan 1
• 3 citations
  Increased frequency of GNPAT p.D519G in compound HFE p.C282Y/p.H63D heterozygotes with elevated serum ferritin levels.
  Eriza S. Secondes, Daniel F. Wallace, Gautam Rishi, Gordon D. McLaren, Christine E. McLaren, Wen-Pin Chen, Louise E. Ramm, Lawrie W. Powell, Grant A. Ramm, James C. Ba...> ;Blood Cells, Molecules & Diseases. 2020 Nov 1
• 20 citations
  Prevalence of iron deficiency in 62,685 women of seven race/ethnicity groups: The HEIRS Study.
  James C. Barton, Howard H. Wiener, Ronald T. Acton, Paul C. Adams, John H. Eckfeldt, Victor R. Gordeuk, Emily L. Harris, Christine E. McLaren, Helen Harrison, Gordon D...> ;Plos One. 2020 Apr 23
• 21 citations
  Cirrhosis in Hemochromatosis: Independent Risk Factors in 368 HFE p.C282Y Homozygotes.
  James C. Barton, Christine E. McLaren, Wen-Pin Chen, Grant A. Ramm, Gregory J. Anderson, Lawrie W. Powell, V. Nathan Subramaniam, Paul C. Adams, Pradyumna D. Phatak, L...> ;Annals of Hepatology. 2018 Aug 24
• 36 citations
  Therapeutic recommendations in HFE hemochromatosis for p.Cys282Tyr (C282Y/C282Y) homozygous genotype
  Paul C. Adams, Albert Altes, Pierre Brissot, Barbara Butzeck, Ioav Cabantchik, Rodolfo D. Cançado, Sonia Distante, Patricia J. Evans, Robert W. Evans, Tomas Ganz, Dome...> ;Hepatology International. 2018 Mar 27
• Cirrhosis in Hemochromatosis: Independent Risk Factors in 368 HFE p.C282Y Homozygotes.
  Barton, J. C.,McLaren, C. E.,Chen, W. P.,Ramm, G. A.,Anderson, G. J.,Powell, L. W.,Subramaniam, V. N.,Adams, P. C.,Phatak, P. D.,Gurrin, L. C.,Phillips, J. D.,Parker, ...> ;Ann Hepatol. 2018 Jan 01
• 12 citations
  GNPAT p.D519G is independently associated with markedly increased iron stores in HFE p.C282Y homozygotes.
  James C. Barton, Wen-Pin Chen, Mary J. Emond, Pradyumna D. Phatak, V. Nathan Subramaniam, Paul C. Adams, Lyle C. Gurrin, Gregory J. Anderson, Grant A. Ramm, Lawrie W. ...> ;Blood Cells, Molecules & Diseases. 2017 Mar 1
• 1 citations
  Reply to HEP 16‐0784.R1 and HEP 16‐0898
  Gordon D. McLaren, James C. Barton, Grant A. Ramm, Mary J. Emond, V. Nathan Subramaniam, Pradyumna D. Phatak, Paul C. Adams, Lawrie W. Powell, Lyle C. Gurrin, Gregory ...> ;Hepatology. 2017 Mar 1
• 5 citations
  The D519G Polymorphism of Glyceronephosphate O-Acyltransferase Is a Risk Factor for Familial Porphyria Cutanea Tarda.
  Colin P. Farrell, Jessica Overbey, Hetanshi Naik, Danielle Nance, Gordon D. McLaren, Christine E. McLaren, Luming Zhou, Robert J. Desnick, Charles J. Parker, John D. P...> ;Plos One. 2016 Sep 23
• Reply.
  McLaren, C. E., Barton, J. C., Subramaniam, V. N., Ramm, G. A., Phatak, P. D., Emond, M. J., Gurrin, L. C., Adams, P. C., Powell, L. W., Anderson, G. J., McLaren, G. D.> ;Hepatology (Baltimore, Md.). 2016 Feb 5
• Study Site Differences in GNPAT p.D519G (rs11558492) Allele Frequencies in Men with HFE Homozygosity
  Christine E. McLaren, James C. Barton, Pradyumna D. Phatak, Mary J. Emond, V. Nathan Subramaniam, Lyle C. Gurrin, Paul C. Adams, Lawrie W. Powell, Grant A. Ramm, Grego...> ;Hepatology. 2015 Sep 1
• 63 citations
  Exome sequencing in HFE C282Y homozygous men with extreme phenotypes identifies a GNPAT variant associated with severe iron overload.
  Christine E. McLaren, Mary J. Emond, V. Nathan Subramaniam, Pradyumna D. Phatak, James C. Barton, Paul C. Adams, Justin B. Goh, Cameron J. McDonald, Lawrie W. Powell, ...> ;Hepatology. 2015 Aug 1
• 4 citations
  Reply: To PMID 25605615.
  Christine E. McLaren, Mary J. Emond, V. N. Subramaniam, Pradyumna D. Phatak, James C. Barton, Paul C. Adams, L. W. Powell, Lyle C. Gurrin, Grant A. Ramm, Gregory J. An...> ;Hepatology. 2015 Jun 3
• 16 citations
  Elevated transferrin saturation, health-related quality of life and telomere length.
  Arch G. Mainous, Robert U. Wright, Mary M. Hulihan, Waleed O. Twal, Christine E. McLaren, Vanessa A. Diaz, Gordon D. McLaren, W. Scott Argraves, Althea M. Grant> ;Biometals. 2014 Feb 1
• 22 citations
  HFE Mutations in Caucasian Participants of the Hemochromatosis and Iron Overload Screening Study with Serum Ferritin Level <1000 μg/L
  Paul C. Adams, Christine E. McLaren, Mark Speechley, Gordon D. McLaren, James C. Barton, John H. Eckfeldt> ;Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie. 2013 Jul 1
• 26 citations
  Association Between Celiac Disease and Iron Deficiency in Caucasians, but Not Non-Caucasians
  Joseph A. Murray, Stela McLachlan, Paul C. Adams, John H. Eckfeldt, Chad Garner, Chris D. Vulpe, Victor R. Gordeuk, Tricia L. Brantner, Catherine Leiendecker-Foster, A...> ;Clinical Gastroenterology and Hepatology. 2013 Jul 1
• 20 citations
  Randomized Trial of Physician Alerts for Thromboprophylaxis after Discharge
  Gregory Piazza, Frederick A. Anderson, Thomas L. Ortel, Michael J Cox, David J. Rosenberg, Shahram Rahimian, William J. Pendergast, Gordon D. McLaren, James A. Welker,...> ;The American Journal of Medicine. 2013 May 1
• 16 citations
  Telomere length and elevated iron: the influence of phenotype and HFE genotype.
  Arch G. Mainous, Robert U. Wright, Mary M. Hulihan, Waleed O. Twal, Christine E. McLaren, Vanessa A. Diaz, Gordon D. McLaren, W. Scott Argraves, Althea M. Grant> ;American Journal of Hematology. 2013 Jun 1
• 15 citations
  New mechanistic explanation for the localization of ulcers in the rat duodenum: Role of iron and selective uptake of cysteamine
  Tetyana Khomenko, Joanna Kolodney, John T. Pinto, Gordon D. McLaren, Xiaoming Deng, Longchuan Chen, Ganna Tolstanova, Brankica Paunovic, Boris F. Krasnikov, Neil Hoa, ...> ;Archives of Biochemistry and Biophysics. 2012 Sep 1
• 41 citations
  Associations between single nucleotide polymorphisms in iron-related genes and iron status in multiethnic populations.
  Christine E. McLaren, Stela McLachlan, Chad Garner, Chris D. Vulpe, Victor R. Gordeuk, John H. Eckfeldt, Paul C. Adams, Ronald T. Acton, Joseph A. Murray, Catherine Le...> ;Plos One. 2012 Jun 22
• 33 citations
  Stimulated erythropoiesis with secondary iron loading leads to a decrease in hepcidin despite an increase in bone morphogenetic protein 6 expression.
  David M. Frazer, Sarah J. Wilkins, Deepak Darshan, Alison C. Badrick, Gordon D. McLaren, Gregory J. Anderson> ;British Journal of Haematology. 2012 Jun 1
• 23 citations
  Dietary iron intake and serum ferritin concentration in 213 patients homozygous for the HFEC282Y hemochromatosis mutation
  Victor R. Gordeuk, Laura C. Lovato, James C. Barton, Mara Z. Vitolins, Gordon D. McLaren, Ronald T. Acton, Christine E. McLaren, Emily L. Harris, Mark Speechley, John ...> ;Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie. 2012 Jun 1
• 10 citations
  Probability of C282Y homozygosity decreases as liver transaminase activities increase in participants with hyperferritinemia in the hemochromatosis and iron overload s...
  Paul C. Adams, Mark Speechley, James C. Barton, Christine E. McLaren, Gordon D. McLaren, John H. Eckfeldt> ;Hepatology. 2012 Jun 1
• 6 citations
  IRon overload screeNing tool (IRON): Development of a tool to guide screening in primary care
  Arch G. Mainous, Vanessa A. Diaz, Charles J. Everett, Michele E. Knoll, Mary M. Hulihan, Althea M. Grant, Christine E. McLaren, Gordon D. McLaren> ;American Journal of Hematology. 2011 Sep 1
• 46 citations
  Genome-Wide Association Study Identifies Genetic Loci Associated with Iron Deficiency
  Christine E. McLaren, Chad Garner, C.C. Constantine, Stela McLachlan, Chris D. Vulpe, Beverly M. Snively, Victor R. Gordeuk, Deborah A. Nickerson, James D. Cook, Cathe...> ;Plos One. 2011 Mar 31
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