GrantVincentBochicchioMD

General Surgery • Saint Louis, MO

Trauma Surgery & Surgical Critical Care

Professor, Surgery, Washington University School of Medicine

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Office
4921 Parkview Pl
Saint Louis, MO 63110
Phone+1 314-362-5298

Fax+1 314-362-5743
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Education & Training

University of MarylandFellowship, Surgical Critical Care, 1998 - 1999
Penn State Milton S Hershey Medical CenterResidency, Surgery, 1993 - 1998
Pennsylvania State University College of MedicineClass of 1993

Certifications & Licensure

IL State Medical License 2019 - 2026
MO State Medical License 2011 - 2025
MD State Medical License 1999 - 2024
PA State Medical License 1994 - 2024
American Board of Surgery Surgery
American Board of Surgery Surgical Critical Care

Awards, Honors, & Recognition

Fellow American College of Surgeons

Clinical Trials

Trial of Supplemental Parenteral Nutrition in Under and Over Weight Critically Ill Patients (TOP-UP) Start of enrollment: 2011 Jun 01
Terminated
Phase 3
Glyburide Healthy Volunteer Study Start of enrollment: 2013 Jan 01
Completed
Phase 1
Multi-Center Study To Examine The Use Of Flex HD® And Strattice In The Repair Of Large Abdominal Wall Hernias Start of enrollment: 2013 Jul 01
Completed
Phase 4
Hemodynamic Instability Index: The Impact to Care With a New Predictive Indicator Start of enrollment: 2016 Mar 01
Terminated
Not Applicable
MANAGE Automated Glucose Monitoring Start of enrollment: 2014 Apr 01
Unknown status
Not Applicable
ClotFoam as an Adjunct to Hemostasis in Abdominal Surgery - Liver Bleeding is Encountered Start of enrollment: 2014 Jul 01
Unknown status
Phase 1
Sigh Ventilation to Increase Ventilator-Free Days in Victims of Trauma at Risk for Acute Respiratory Distress Syndrome Start of enrollment: 2016 Apr 01
Completed
Not Applicable
A Prospective Case Series Evaluating Surgimend Mp® In Patients Undergoing Complex Abdominal Hernia Repair Start of enrollment: 2018 Jan 03
Completed
Not Applicable
Glucose Time-In-Range Development Evaluation Start of enrollment: 2018 Sep 06
Terminated
Not Applicable
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Publications & Presentations

PubMed

Negative Pressure Wound Therapy With and Without Instillation in Necrotizing Soft Tissue Infections.
Erin Dawson, Ricardo Fonseca, Melissa Canas, Leonardo Diaz, Alejandro De Filippis, John Mazuski, Kelly M Bochicchio, Grant V Bochicchio, Hussain Afzal> ;Surgical Infections. 2024 Apr 1
Does Negative Pressure Wound Therapy Impact the Outcome for Patients With Necrotizing Soft Tissue Infection Infected With Anaerobic Bacteria?
Erin Dawson, Ricardo Fonseca, Melissa Canas, Leonardo Diaz, Alejandro De Filippis, Kelly M Bochicchio, Grant V Bochicchio, Hussain Afzal> ;Surgical Infections. 2024 Apr 1
3 citations
Sigh Ventilation in Patients With Trauma: The SiVent Randomized Clinical Trial.
Richard K Albert, Gregory J Jurkovich, John Connett, Erika S Helgeson, Angela Keniston, Helen Voelker, Sarah Lindberg, Jennifer L Proper, Grant Bochicchio, Deborah M S...> ;JAMA. 2023 Nov 28
1 citations
Ludwig's Angina: Higher Incidence and Worse Outcomes Associated With the Onset of the Coronavirus Disease 2019 Pandemic.
Melissa Canas, Ricardo Fonseca, Alejandro De Filippis, Leonardo Diaz, Aaron Day, Jennifer Leonard, Kelly Bochicchio, Grant V Bochicchio, Mark Hoofnagle, Hussain Afzal> ;Surgical Infections. 2023 Nov 1
3 citations
Doing more with less: low-titer group O whole blood resulted in less total transfusions and an independent association with survival in adults with severe traumatic he...
Susan M Shea, Emily P Mihalko, Liling Lu, Kimberly A Thomas, Douglas Schuerer, Joshua B Brown, Grant V Bochicchio, Philip C Spinella> ;Journal of Thrombosis and Haemostasis. 2024 Jan 1
3 citations
Effect of P2Y12 Inhibitors on Organ Support-Free Survival in Critically Ill Patients Hospitalized for COVID-19: A Randomized Clinical Trial.
Jeffrey S Berger, Matthew D Neal, Lucy Z Kornblith, Michelle N Gong, Harmony R Reynolds, Mary Cushman, Andrew D Althouse, Patrick R Lawler, Bryan J McVerry, Keri S Kim...> ;JAMA Network Open. 2023 May 1
Defects in vein valve PROX1/FOXC2 antithrombotic pathway in endothelial cells drive the hypercoagulable state induced by trauma and critical illness.
Mark H Hoofnagle, Annie Hess, Margaret Nalugo, Sarbani Ghosh, Shin-Wen Hughes, Anja Fuchs, John D Welsh, Mark L Kahn, Grant V Bochicchio, Gwendalyn J Randolph, Jennife...> ;The Journal of Trauma and Acute Care Surgery. 2023 Aug 1
2 citations
Reduction of Surgical Site Infection After Trauma Laparotomy Through Use of a Specific Protocol for Antibiotic Prophylaxis.
John E Mazuski, William J Symons, Stephen Jarman, Bryan Sato, William Carroll, Grant V Bochicchio, John P Kirby, Douglas J Schuerer> ;Surgical Infections. 2023 Mar 1
Open Mandible and Maxillary Fractures Associated with Higher Risk of Infection in Victims of Assault.
Melissa Canas, Ricardo Fonseca, Leonardo Diaz, Alejandro De Filippis, Jose A Aldana, Chris Machica, Jennifer Leonard, Stephen Y Liang, Kelly Bochicchio, Grant V Bochic...> ;Surgical Infections. 2023 May 1
6 citations
The risk of thromboembolic events with early intravenous 2- and 4-g bolus dosing of tranexamic acid compared to placebo in patients with severe traumatic bleeding: A s...
Philip C Spinella, Kelly Bochicchio, Kimberly A Thomas, Amanda Staudt, Susan M Shea, Anthony E Pusateri, Douglas Schuerer, Jerrold H Levy, Andrew P Cap, Grant Bochicchio> ;Transfusion. 2022 Aug 1
2 citations
When REBOA grows wings: Resuscitative endovascular balloon occlusion of the aorta to facilitate aeromedical transport.
Jason A Snyder, Douglas J E Schuerer, Grant V Bochicchio, Mark H Hoofnagle> ;Trauma Case Reports. 2022 Apr 1
72 citations
Effect of P2Y12 Inhibitors on Survival Free of Organ Support Among Non-Critically Ill Hospitalized Patients With COVID-19: A Randomized Clinical Trial.
Jeffrey S Berger, Lucy Z Kornblith, Michelle N Gong, Harmony R Reynolds, Mary Cushman, Yu Cheng, Bryan J McVerry, Keri S Kim, Renato D Lopes, Bassel Atassi, Scott Berr...> ;JAMA. 2022 Jan 18
7 citations
Extrathoracic multiple trauma dysregulates neutrophil function and exacerbates pneumonia-induced lung injury.
Jennifer M. Leonard, Christina X. Zhang, Liang Lu, Mark H. Hoofnagle, Anja Fuchs, Regina A. Clemens, Sarbani Ghosh, Shin-Wen Hughes, Grant V. Bochicchio, Richard S. Ho...> ;The Journal of Trauma and Acute Care Surgery. 2021 Jun 1
1 citations
Pseudomonas aeruginosa Pneumonia Causes a Loss of Type-3 and an Increase in Type-1 Innate Lymphoid Cells in the Gut.
Anja Fuchs, Sarbani Ghosh, Shin-Wen Chang, Grant V. Bochicchio, Isaiah R. Turnbull> ;The Journal of Surgical Research. 2021 May 2
5 citations
Critical Ethics: How to Balance Patient Autonomy With Fairness When Patients Refuse Coronavirus Disease 2019 Testing
Piroska K. Kopar, Jessica B. Kramer, Douglas Brown, Grant V. Bochicchio> ;Critical Care Explorations. 2021 Jan 22
1 citations
COVER: A Curriculum in the Management of Soft Tissue Injury and Infection for Junior Surgery Residents
Emily J. Onufer, Erin G. Andrade, Angelia DeClue, Grant V. Bochicchio, Paul E. Wise, Mary E. Klingensmith, Stephen R. Eaton, John P. Kirby, Laurie J. Punch> ;Journal of Graduate Medical Education. 2021 Feb 1
3 citations
Stem cell and niche regulation in human short bowel syndrome
Vered Gazit, Elzbieta A. Swietlicki, Miranda U. Liang, Adam Surti, Raechel McDaniel, David M. Alvarado, Matthew A. Ciorba, Grant V. Bochicchio, Obeid N. Ilahi, John P....> ;JCI Insight. 2020 Dec 3
22 citations
The Immunologic Effect of Early Intravenous Two and Four Gram Bolus Dosing of Tranexamic Acid Compared to Placebo in Patients With Severe Traumatic Bleeding (TAMPITI):...
Philip C. Spinella, Kimberly A. Thomas, Isaiah R. Turnbull, Anja Fuchs, Kelly Bochicchio, Douglas J. E. Schuerer, Stacey Reese, Adrian A Coleoglou Centeno, Christopher...> ;Frontiers in Immunology. 2020 Sep 8
73 citations
The use of low-titer group O whole blood is independently associated with improved survival compared to component therapy in adults with severe traumatic hemorrhage
Susan M. Shea, Amanda M Staudt, Kimberly A. Thomas, Douglas J. E. Schuerer, James E Mielke, Danielle Folkerts, Ethan Lowder, Callista Martin, Grant V. Bochicchio, Phil...> ;Transfusion. 2020 Jun 1
1 citations
The Importance of Universal Preprocedural Testing for the Novel Coronavirus 2019
Felicia Zhang, William C. Chapman, Grant V. Bochicchio, Obeid N. Ilahi, Tiffany M. Osborn> ;Critical Care Explorations. 2020 May 22
1 citations
Acute Acalculous Cholecystitis-Associated Bacteremia Has Worse Outcome
Javier Enrique Rincon, Rohit K Rasane, Jose A. Aldana, Christina Xinyue Zhang, Ricardo A. Fonseca, Qiao Zhang, Kelly Bochicchio, Obeid N. Ilahi, Grant V. Bochicchio> ;Surgical Infections. 2021 Feb 11
Temporary Abdominal Closure Is Associated with Increased Risk for Fungal Intra-Abdominal Infections in Trauma Patients.
Christina Xinyue Zhang, Rohit R. Rasane, Qiao Zhang, Ricardo A. Fonseca, Jose A. Aldana, Javier Enrique Rincon, Maya J. Sorini, Kelly Bochicchio, Jennifer M. Leonard, ...> ;Surgical Infections. 2020 Oct 23
3 citations
Inadequate Antibiotic Therapy Results in Higher Recurrence Rate after Drainage of Complicated Peri-Rectal Abscess.
Rohit K Rasane, Adrian A Centeno Coleoglou, Christopher B Horn, Marlon Torres, Eden Nohra, Qiao Zhang, Kelly Bochicchio, Obeid N. Ilahi, John E. Mazuski, Grant V. Boch...> ;Surgical Infections. 2020 Nov 6
3 citations
Fifteen-minute Frequency of Glucose Measurements and the Use of Threshold Alarms: Impact on Mitigating Dysglycemia in Critically Ill Patients
Grant V. Bochicchio, Stanley A. Nasraway, Laura J. Moore, Anthony P. Furnary, Eden Nohra, Kelly Bochicchio, James C. Boyd, David I. Bruns, Irl B. Hirsch, Jean-Charles ...> ;Journal of Diabetes Science and Technology. 2021 Mar 1
3 citations
Are Patients with Perforated Peptic Ulcers Who are Negative for Helicobacter pylori at a Greater Risk
Rohit K Rasane, Christopher B Horn, Adrian A Coleoglou Centeno, Nicholas B Fiore, Marlon Torres Barboza, Qiao Zhang, Kelly Bochicchio, Laurie J. Punch, Grant V. Bochic...> ;Surgical Infections. 2019 Aug 14
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Press Mentions

Drug Has Minimal Effects in Stopping Excessive Bleeding in Trauma PatientsNovember 19th, 2021
National Clinical Trial to Settle Debate on Managing Airways in EmergenciesMarch 20th, 2020
Successful First Use of Gel-E in a Surgical ModelApril 3rd, 2019
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