GregoryJohnAuneMDPhD

PubMed

• A cohort study on blood coagulation in childhood cancer survivors.
  Andrew D Meyer, Tyler B Hughes, Anjana R Rishmawi, Patty Heard, Shafqat Shah, Gregory J Aune> ;Thrombosis Research. 2023 Jun 1
• 23 citations
  SARS-CoV-2 infection enhances mitochondrial PTP complex activity to perturb cardiac energetics.
  Karthik Ramachandran, Soumya Maity, Alagar R Muthukumar, Soundarya Kandala, Dhanendra Tomar, Tarek Mohamed Abd El-Aziz, Cristel Allen, Yuyang Sun, Manigandan Venkatesa...> ;Iscience. 2022 Jan 21
• 22 citations
  Coronary artery disease surveillance among childhood, adolescent and young adult cancer survivors: A systematic review and recommendations from the International Late ...
  Elvira C. van Dalen, Renée L. Mulder, Eugene Suh, Matthew J. Ehrhardt, Gregory J. Aune, Edit Bardi, Bradley Benson, Jutta Bergler-Klein, Ming H. Chen, Eva Frey, Ulrike...> ;European Journal of Cancer. 2021 Oct 1
• 29 citations
  Doxorubicin-Induced p53 Interferes with Mitophagy in Cardiac Fibroblasts
  Trevi R. Mancilla, Leyla R. Davis, Gregory J. Aune> ;Plos One. 2020 Sep 22
• 43 citations
  IL‐1 receptor antagonist, anakinra, prevents myocardial dysfunction in a mouse model of Kawasaki disease vasculitis and myocarditis
  M Gorelik, Youngho Lee, Masanori Abe, Thomas Andrews, Leyla R. Davis, Jean L. Patterson, Shuang Chen, Timothy R. Crother, Gregory J. Aune, M. Noval Rivas, Moshe Arditi> ;Clinical and Experimental Immunology. 2019 Oct 1
• 50 citations
  Doxorubicin-induced cardiomyopathy in children
  Trevi R. Mancilla, Brian S. Iskra, Gregory J. Aune> ;Comprehensive Physiology. 2019 Jun 12
• 121 citations
  Derivation of Anthracycline and Anthraquinone Equivalence Ratios to Doxorubicin for Late-Onset Cardiotoxicity
  Elizabeth A.M. Feijen, Wendy M. Leisenring, Kayla Stratton, Kirsten K. Ness, Helena J H van der Pal, Elvira C. van Dalen, Gregory T. Armstrong, Gregory J. Aune, Daniel...> ;JAMA Oncology. 2019 Jun 1
• 117 citations
  Cardiovascular Disease in Survivors of Childhood Cancer: Insights Into Epidemiology, Pathophysiology, and Prevention
  Saro H. Armenian, Gregory T. Armstrong, Gregory J. Aune, Eric J. Chow, Matthew J. Ehrhardt, Bonnie Ky, Javid Moslehi, Daniel A. Mulrooney, Paul C. Nathan, Thomas J. Ry...> ;Journal of Clinical Oncology. 2018 Jun 6
• 25 citations
  Aerobic Exercise During Early Murine Doxorubicin Exposure Mitigates Cardiac Toxicity.
  Fei Wang, Brian S. Iskra, Eugenie S. Kleinerman, Claudia Alvarez-Florez, Thomas Andrews, Angela Shaw, Joya Chandra, Keri Schadler, Gregory J. Aune> ;Journal of Pediatric Hematology/oncology. 2018 Jan 1
• Health-care delivery for long-term survivors of childhood cancer.
  Gregory J. Aune> ;Lancet. 2017 Dec 9
• 16 citations
  The tell-tale heart: molecular and cellular responses to childhood anthracycline exposure
  Merry L. Lindsey, Richard A. Lange, Helen Parsons, Thomas Andrews, Gregory J. Aune> ;American Journal of Physiology. Heart and Circulatory Physiology. 2014 Nov 15
• 21 citations
  Negative Elongation Factor Controls Energy Homeostasis in Cardiomyocytes
  Haihui Pan, Kunhua Qin, Zhanyong Guo, Yonggang Ma, Craig April, Xiaoli Gao, Thomas Andrews, Alex Bokov, Jianhua Zhang, Yi Chen, Susan T. Weintraub, Jian-Bing Fan, Dege...> ;Cell Reports. 2014 Apr 10
• 9 citations
  Cardiac assessment in pediatric mice: strain analysis as a diagnostic measurement.
  Thomas Andrews, Merry L. Lindsey, M.B.A Richard A. Lange M.D., Gregory J. Aune> ;Echocardiography. 2014 Mar 1
• 20 citations
  Using proteomics to uncover extracellular matrix interactions during cardiac remodeling
  Nicolle L. Patterson, Rugmani Padmanabhan Iyer, Lisandra E. de Castro Brás, Yaojun Li, Thomas Andrews, Gregory J. Aune, Richard A. Lange, Merry L. Lindsey> ;Proteomics. Clinical Applications. 2013 Aug 1
• 10 citations
  Isolated vaginal myeloid sarcoma in a 16-year-old girl.
  Maria Luisa C. Policarpio-Nicolas, Philip T. Valente, Gregory J. Aune, Russell A. Higgins> ;Annals of Diagnostic Pathology. 2012 Oct 1
• 35 citations
  Von Hippel-Lindau-coupled and transcription-coupled nucleotide excision repair-dependent degradation of RNA polymerase II in response to trabectedin.
  Gregory J. Aune, Kazutaka Takagi, Olivier Sordet, Josée Guirouilh-Barbat, Smitha Antony, Vilhelm A. Bohr, Yves Pommier> ;Clinical Cancer Research. 2008 Oct 15
• 36 citations
  p21CDKN1A allows the repair of replication-mediated DNA double-strand breaks induced by topoisomerase I and is inactivated by the checkpoint kinase inhibitor 7-hydroxy...
  Takahisa Furuta, R. L. Hayward, Linghua Meng, H. Takemura, Gregory J. Aune, William M. Bonner, Mirit I. Aladjem, Kurt W. Kohn, Yves Pommier> ;Oncogene. 2006 May 11
• 377 citations
  Phosphorylation of Histone H2AX and Activation of Mre11, Rad50, and Nbs1 in Response to Replication-dependent DNA Double-strand Breaks Induced by Mammalian DNA Topoiso...
  Takahisa Furuta, H. Takemura, Zhi Yong Liao, Gregory J. Aune, Christophe E. Redon, Olga A. Sedelnikova, Duane R. Pilch, Emmy P. Rogakou, Arkady Celeste, Hua Tang Chen,...> ;The Journal of Biological Chemistry. 2003 May 30
• 282 citations
  Transcription-coupled Nucleotide Excision Repair as a Determinant of Cisplatin Sensitivity of Human Cells
  Takahisa Furuta, Takahiro Ueda, Gregory J. Aune, Alain Sarasin, Kenneth H. Kraemer, Yves Pommier> ;Cancer Research. 2002 Sep 1
• 80 citations
  Ecteinascidin 743: a novel anticancer drug with a unique mechanism of action.
  Gregory J. Aune, Takahisa Furuta, Yves Pommier> ;Anti-Cancer Drugs. 2002 Jul 1
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Journal Articles

• RNA Polymerase II Pausing Factor NELF Controls Energy Homeostasis in Cardiomyocytes  
  Pan, H, Qin, K, Guo, Z, Ma, Y, April C, Gao, X, Andrews, TG, Bokov, A, Zhang, J, Chen, Y, Weintraub, S, Fan, J, Wang, D, Hu, Y, Aune, GJ, Lindsey, ML, and Li R, Cell Reports, 1/10/2014
• The Tell-Tale Heart: Molecular and Cellular Responses to Childhood Anthracycline Exposure  
  Lindsey, ML, Lange, RA, Parsons H, Andrews, TG, and Aune GJ, American Journal of Physiology: Heart and Circulatory Physiology, 1/1/2014
• Using Proteomics to Uncover Matrix Metalloproteinase Roles in Extracellular Matrix Remodeling  
  Patterson NL, Rugmani PI, Li Y, Andrews TG, Aune GJ, Lange RA, and Lindsey ML, Proteomics Clinical Applications, 1/1/2013
• Von Hippel-Lindau and Transcription-coupled Nucleotide Excision Repair Dependent Degradation of RNA Polymerase II in Response to Trabectedin  
  Aune GJ, Kazutaka T, Sordet O, Guirouilh-Barbat J, Antony S, Bohr W, and Pommier Y, Clinical Cancer Research, 1/15/2008
• Wilms Tumor  
  Aune, GJ, Pediatrics in Review, 1/1/2008
• p21CKDN1A Allows the Repair of Replication-mediated DNA Double-strand Breaks Induced by Topoisomerase I and Inactivated by the Checkpoint Kinase Inhibitor 7-hydroxysta...  
  Furuta T, Hayward RL, Meng LH, Takemura H, Aune GJ, Bommer WM, Aladjem, Kohn KW, and Pommier Y, Oncogene, 1/11/2006
• Phosphorylation of Histone H2AX and Activation of Mre11, Rad50, and Nbs1 in Response to Replication-Dependent DNA-Double-strand Breaks Induced by Mammalian DNA Topoiso...  
  Furuta T, Takemura H, Liao Z, Aune GJ, Redon C, Sedelnikova O, Pilch D, Rogaku E, Celeste A, Tang Chen H, Nussenzweig A, Aladjem M, Bonner W, and Pommier Y, J Biol Chem, 1/30/2003
• Ecteinascidin 743: A Novel Anticancer Drug with a Unique Mechanism of Action  
  Aune GJ, Furuta T, and Pommier Y, Anti-Cancer Drugs, 1/1/2002
• Transcription Coupled-Nucleotide Excision Repair as a Determinant of Cisplatin Sensitivity of Human Cells  
  Furuta T, Ueda T, Aune GJ, Sarasin A, Kraemer KH, and Pommier Y, Cancer Res, 1/1/2002
• Fluids and Electrolytes  
  Aune, GJ, Harriet Lane Handbook
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Abstracts/Posters

• Pediatric Mouse Model of Anthracycline-induced Cardiac Toxicity
  Lindsey, ML, Lange, RA, Andrews, TG, and Aune GJ, Keystone Symposia- Fibrosis: From Bench to Bedside, 1/1/2014
• Pediatric Mouse Model of Anthracycline-Induced Cardiotoxicity
  Andrews TG, Lindsey ML, Lange RA, and Aune GJ, National Translational Sciences Meeting, 1/1/2014
• A Pediatric Mouse Model of Anthracycline-induced Cardiac Toxicity
  Lindsey, ML, Lange, RA, Andrews, TG, and Aune GJ, Keystone Symposia- Fibrosis: From Bench to Bedside, 1/1/2014
• A Pediatric Mouse Model of Anthracycline-induced Cardiac Toxicity
  Lindsey, ML, Lange, RA, Andrews, TG, and Aune GJ, Frontiers in Translational Science, 1/1/2014
• Greehey Shared Resource for Cardiac Function Assessment
  Andrews TG and Aune GJ, Frontiers in Translational Science, 1/1/2014
• A Pediatric Mouse Model of Anthracycline-induced Cardiac Toxicity
  Lindsey, ML, Lange, RA, Andrews, TG, and Aune GJ, Department of Pediatrics Research Day, 1/1/2014
• Greehey Shared Resource for Cardiac Function Assessment
  Aune GJ, Department of Pediatrics Research Day, 1/1/2014
• Analysis of Cardiac Function in a Pediatric Mouse Model of Doxorubicin-Induced Cardiotoxicity Using Echocardiographic Strain Imaging
  Andrews T, Lindsey ML, and Aune GJ, National Translational Sciences Meeting, 1/1/2013
• Pediatric Mouse Model of Anthracycline-Induced Cardiotoxicity
  Andrews TG, Lindsey ML, Lange RA, and Aune GJ, 13th International Conference on Long-Term Complications of Treatment of Children and Adolescents for Cancer, 1/1/2013
• Cardiac Assessment in Pediatric Mice by Strain Analysis
  Lam JP, Frausto-Garcia E, Assanasen C, and Aune GJ, Frontiers in Translational Science, 1/1/2013
• Analysis of Cardiac Function in a Pediatric Mouse Model of Doxorubicin-Induced Cardiotoxicity Using Echocardiographic Strain Imaging
  Aune GJ, Andrews T, and Lindsey ML, Department of Pediatrics Research Day, 1/1/2013
• Cardiac Assessment in Pediatric Mice by Strain Analysis
  Andrews T, Lindsey ML, and Aune GJ, Department of Pediatrics Research Day, 1/1/2013
• Retrospective Chart Review of Antimetabolite Toxicities in Pediatric Cancer Patients
  Lam JP, Frausto-Garcia E, Assanasen C, and Aune GJ, Department of Pediatrics Research Day, 1/1/2013
• Pediatric Mouse Model of Anthracycline-Induced Cardiotoxicity
  Andrews TG, Lindsey ML, Lange RA, and Aune GJ, 13th International Conference on Long-Term Complications of Treatment of Children and Adolescents for Cancer, Texas Regional CTSA Consortium Annual Meeting, 1/1/2013
• Retrospective Review of Cardiovascular Health in Pediatric Cancer Survivors in South Texas
  Aune GJ, Dickson, F, and Tomlinson, GE, Cancer Prevention Research Institute of Texas Annual Meeting, 12th International Conference on Long-Term Complications of Treatment of Children and Adolescents for Cancer, 1/1/2012
• Analysis of Cardiac Function in a Pediatric Mouse Model of Doxorubicin-Induced Cardiotoxicity Using Echocardiographic Strain Imaging
  Aune GJ, Andrews T, and Lindsey ML, Cancer and the Heart, 1/1/2012
• Retrospective Review of Cardiovascular Health in Pediatric Cancer Survivors in South Texas
  Aune GJ, Dickson, F, and Tomlinson, GE, Multiple presentations, 1/1/2012
• Analysis of Cardiac Function in a Pediatric Mouse Model of Doxorubicin-Induced Cardiotoxicity Using Echocardiographic Strain Imaging
  Aune GJ, Andrews T, and Lindsey ML, Cancer Prevention Research Institute of Texas Annual Meeting, 1/1/2012
• Retrospective Chart Review of Antimetabolite Toxicities in Pediatric Cancer Patients
  Lam JP, Frausto-Garcia E, Assanasen C, and Aune GJ, Medical Student Research Day, 1/1/2012
• EWS-Fli1 Fusion Protein Expression in Ewing's Sarcoma Tumors is Inhibited by Ecteinascidin 743
  Aune GJ, Rao VA, AchiriMofor ND, Merchant MD, Merino ME, Mackall CL, and Pommier YG, Pediatric Academic Societies' Annual Meeting, 1/1/2005
• Sensitivity to the Novel Anticancer Agent Ecteinascidin 743 Requires VHL-dependent Degradation of RNA Polymerase II Large Subunit
  Aune G, Vasselli J, Linehan W, and Pommier Y, Proceedings of the American Association for Cancer Research, 1/1/2004
• RNA Polymerase II Degradation Induced by Ecteinascidin 743 is Dependent on Transcription-coupled Nucleotide Excision Repair and Predicts Drug Sensitivity
  Aune G, Sordet O, Bohr V, and Pommier Y, Proceedings of the American Association for Cancer Research, 1/1/2004
• VHL-dependent Degradation of RNA Polymerase II Large Subunit Enhances Sensitivity to the Novel Anticancer Agent Ecteinascidin 743
  Aune GJ, Vasselli JR, Linehan WM, Pommier YG, NIH Young Investigators Retreat, 1/1/2004
• The Cell Cycle Checkpoint Abrogator 7-hydroxystaurosporin (UCN-01), Enhances Phosphorylation of Histone H2AX and Abrogates P21 Induction in Response to Camptothecin
  Furuta F, Takemura H, Hayward L, Aune G, Liao Z, Aladjem M, Bonner W, and Pommier Y, Proceedings of the American Association for Cancer Research, 1/1/2003
• The Topoisomerase I Inhibitor Camptothecin Induces the Phosphorylation of RNA Polymerase II Subunit
  Sordet O, Aune G, and Pommier Y, Proceedings of the American Association for Cancer Research, 1/1/2003
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Lectures

• Preclinical Models to Study Anthracycline-Induced Cardiotoxicity 
  1/1/2014
• Modeling Anthracycline-induced Cardiac Injury in Young Mice 
  University of Texas Health Science Center at San Antonio - 1/1/2014
• Careers in Biomedical Science 
  1/1/2014
• Deviant Chromosome Engineering by miRNAs 
  University of Texas Health Science Center at San Antonio - 1/1/2014
• Preclinical Evaluation of Chemotherapy-induced Cardiotoxicity 
  Institute for Drug Development. University of Texas Health Science Center at San Antonio - 1/1/2014
• Pediatric Mouse Model of Anthracycline Cardiac Toxicity 
  University of Texas Health Science Center at San Antonio - 1/1/2013
• Pediatric Cancer Survivorship in the 21st Century 
  University of Texas Health Science Center at San Antonio - 1/1/2013
• Pediatric Mouse Model of Anthracycline-Induced Cardiac Toxicity 
  1/1/2013
• Creating and Implementing a Junior Faculty Career Plan 
  San Antonio Cardiovascular Proteomics Center - 1/1/2012
• Analysis of Cardiac Function in a Pediatric Mouse Model of Doxorubicin-Induced Cardiotoxicity Using Echocardiographic Strain Imaging 
  San Antonio Cardiovascular Proteomics Center - 1/1/2012
• The Tell-Tale Heart: Late Effects in Pediatric Cancer Survivors 
  University of Texas Health Science Center at San Antonio - 1/1/2012
• Cancer Therapy in the 21st Century: The Tell-Tale Heart 
  Cancer Therapy and Research Center. University of Texas Health Science Center at San Antonio - 1/1/2012
• Retrospective Review of Cardiovascular Health in Pediatric Cancer Survivors in South Texas 
  1/1/2011
• Invited Commencement Speaker 
  University Texas San Antonio Center for Professional Excellence - 1/1/2010
• Post Transplant Lymphoproliferative Disorder 
  1/1/2010
• AFLAC-Macy's Holiday Fund Raising Check Presentation 
  Greehey Children's Cancer Research Institute - 1/1/2010
• Hyundai Hope on Wheels Check Presentation. Recipient and Invited Speaker 
  Greehey Children's Cancer Research Institute - 1/1/2010
• Dance Marathon Keynote Speaker for FTK Family Hour 
  University of Texas San Antonio - 1/1/2010
• Pediatric Cancer Therapy: The Gift that Keeps on Giving 
  1/1/2006
• Sensitivity to the Novel Anticancer Agent Ecteinascidin 743 Requires VHL-dependent Degradation of RNA Polymerase II Large Subunit 
  1/1/2004
• RNA Polymerase II Degradation Induced by Ecteinascidin 743 is Dependent on Transcription-coupled Nucleotide Excision Repair and Predicts Drug Sensitivity 
  1/1/2004
• Careers in Biomedical Sciences 
  1/1/2002
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Other

• Working with Heart: St. Baldrick's Researcher Survived Childhood Cancer as a Teen 
  Feature Story. St. Baldrick's Foundation Blog
  http://www.stbaldricks.org/blog/post/working-with-heart-st-baldricks-researcher-survived-childhood-cancer-as-a-teen/
  1/28/2014
• 7 Steps to Building a St. Baldrick's Event from a Veteran VEO 
  Feature Story. St. Baldrick's Foundation Blog
  http://www.stbaldricks.org/blog/post/7-steps-to-building-a-st-baldricks-event-from-a-veteran-veo/
  1/24/2014
• UTHSC Researchers Study Pediatric Cancer Treatment Consequences in Adult Survivors 
  Feature Story. BioNews Texas
  http://bionews-tx.com/news/2014/07/21/uthsc-researchers-study-pediatric-cancer-treatment-consequences-in-adult-survivors/
  1/21/2014
• These Pediatric Oncologists Weren't Expecting This Great News 
  Featured Investigator. St. Baldrick's 2014 Summer Grants Announcement Video
  http://www.stbaldricks.org/blog/post/these-pediatric-oncologists-werent-expecting-this-great-news-video
  1/16/2014
• UT Health Science Center Researcher Receives St. Baldrick's Foundation Grant to Study Long-Term Effects of Chemotherapy on Children 
  Feature Story. BioNews Texas
  http://bionews-tx.com/news/2014/08/13/ut-health-science-center-researcher-receives-st-baldricks-foundation-grant-to-study-long-term-effects-of-chemotherapy-on-children/
  1/13/2014
• Hyundai Gives $250,000 to Cardiac Disease Study in Childhood Cancer Survivors 
  Feature Story. BioNews Texas
  http://bionews-tx.com/news/2014/09/10/hyundai-gives-250000-to-cardiac-disease-study-in-childhood-cancer-survivors/
  1/10/2014
• UT Health Science Center to Benefit from Cancer Research Funding 
  Feature Story. San Antonio Business Journal
  http://www.bizjournals.com/sanantonio/news/2014/09/05/ut-health-science-center-to-benefit-from-cancer.html
  1/5/2014
• Taking It to Heart: Researcher Felt Cancer Firsthand 
  Feature Article. Mission Magazine
  http://uthscsa.edu/mission/article.asp?id=874
  University of Texas Health Science Center at San Antonio - 1/1/2013
• THON Sets the Tone for 2012 FTK Dance Marathon at UTSA 
  The FTK Blog
  http://ftkdmatutsa.wordpress.com/tag/greg-aune/
  1/29/2012
• HSC Receives $50,000 from St. Baldrick's Foundation 
  News Brief. Health Science Center News
  1/1/2012
• Adult Stem Cell Regulations Approved by the Texas Medical Board 
  Interview. Texas Public Radio. For the Report
  1/1/2012
• Focus on South Texas: Cancer Survivorship 
  Panel Participant.  KABB Fox 29 San Antonio
  1/1/2012
• Late-night Lesson Leads to Career Studying Chemotherapy 
  Feature Article. Pacific Lutheran University Scene Magazine
  http://issuu.com/plu-archives/docs/2011-2012_v.42_no.1-3/122
  1/1/2012
• Saving Pediatric Cancer Survivors 
  Feature Story: University of Texas Health Science Center at San Antonio, "Our Stories"
  http://www.uthscsa.edu/stories/cardiac-research-pediatric
  1/1/2012
• PhD Dissertation: RNA Polymerase II Large Subunit Degradation Induced by Ecteinascidin 743: Molecular Characterization and Subsequent Rational Investigation of Antit... 
  University of Texas-Houston Graduate School of Biomedical Sciences
  1/1/2005
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