GregoryADemopulosMD

PubMed

• 1 citations
  Inhibition of the Lectin Pathway of Complement Activation Reduces Acute Respiratory Distress Syndrome Severity in a Mouse Model of SARS-CoV-2 Infection.
  Youssif M Ali, George W Carnell, Stefano Fumagalli, Domenico Mercurio, Serena Seminara, Nicholas J Lynch, Priyanka Khatri, Chanuka H Arachchilage, Luca Mascheroni, Cle...> ;The Journal of Infectious Diseases. 2024 Mar 14
• 3 citations
  Inhibition of the lectin pathway of complement activation reduces LPS-induced acute respiratory distress syndrome in mice.
  Youssif M Ali, Nicholas J Lynch, Ahmed A Shaaban, Dina E Rizk, Shaymaa H Abdel-Rahman, Priyanka Khatri, Munehisa Yabuki, Sadam Yaseen, Thomas Dudler, Gregory Demopulos...> ;Frontiers in Immunology. 2023 Jan 1
• 6 citations
  Inhibition of the lectin pathway of complement ameliorates hypocomplementemia and restores serum bactericidal activity in patients with severe COVID-19.
  Nicholas J Lynch, Andrew C Y Chan, Youssif M Ali, Priyanka Khatri, Ifeoluwa E Bamigbola, Gregory Demopulos, Muriel Paganessi, Alessandro Rambaldi, Wilhelm J Schwaeble> ;Clinical and Translational Medicine. 2022 Jul 1
• 5 citations
  Secondary Complement Deficiency Impairs Anti-Microbial Immunity toandDuring Severe Acute COVID-19.
  Youssif M Ali, Nicholas J Lynch, Priyanka Khatri, Ifeoluwa E Bamigbola, Andrew C Y Chan, Munehisa Yabuki, Gregory A Demopulos, Jonathan L Heeney, Sumita Pai, Helen Bax...> ;Frontiers in Immunology. 2022 Jan 1
• 3 citations
  Selective inhibition of phosphodiesterase 7 enzymes reduces motivation for nicotine use through modulation of mesolimbic dopaminergic transmission.
  Roberto Ciccocioppo, Giordano de Guglielmo, Hong Wu Li, Miriam Melis, Lucia Caffino, Quienwei Shen, Ana Domi, Fabio Fumagalli, Gregory Demopulos, George Gaitanaris> ;The Journal of Neuroscience. 2021 Jun 1
• 93 citations
  Lectin Pathway Mediates Complement Activation by SARS-CoV-2 Proteins.
  Youssif M. Ali, Matteo Ferrari, Nicholas J. Lynch, Sadam Yaseen, Thomas Dudler, Sasha Gragerov, Gregory A. Demopulos, Jonathan L. Heeney, Wilhelm Schwaeble> ;Frontiers in Immunology. 2021 Jan 1
• 11 citations
  Activation of peroxisome proliferator-activated receptor γ reduces alcohol drinking and seeking by modulating multiple mesocorticolimbic regions in rats.
  Yannick Fotio, Anna Maria Borruto, Federica Benvenuti, Gregory Demopulos, George Gaitanaris, Marisa Roberto, Roberto Ciccocioppo> ;Neuropsychopharmacology. 2021 Jan 1
• 102 citations
  Endothelial injury and thrombotic microangiopathy in COVID-19: Treatment with the lectin-pathway inhibitor narsoplimab.
  Alessandro Rambaldi, Giuseppe Gritti, Maria Caterina Mico, Marco Frigeni, Gianmaria Borleri, Anna Salvi, Francesco Landi, Chiara Pavoni, Aurelio Sonzogni, Andrea Giana...> ;Immunobiology. 2020 Aug 9
• 5 citations
  Further evidence for the involvement of the PPARγ system on alcohol intake and sensitivity in rodents
  Esi Domi, Ana Domi, Massimo Ubaldi, Lorenzo Somaini, Gregory Demopulos, George Gaitanaris, Roberto Ciccocioppo> ;Psychopharmacology. 2020 Jul 16
• 23 citations
  Activation of PPARγ Attenuates the Expression of Physical and Affective Nicotine Withdrawal Symptoms through Mechanisms Involving Amygdala and Hippocampus Neurotransmi...
  Esi Domi, Francesca Felicia Caputi, Patrizia Romualdi, Ana Domi, Giulia Scuppa, Sanzio Candeletti, Alison Lynn Atkins, Markus Heilig, Gregory Demopulos, George Gaitana...> ;The Journal of Neuroscience. 2019 Nov 4
• 30 citations
  Protection against alcohol-induced neuronal and cognitive damage by the PPARγ receptor agonist pioglitazone
  Andrea Cippitelli, Esi Domi, Massimo Ubaldi, James C. Douglas, Hong Wu Li, Gregory Demopulos, George Gaitanaris, Marisa Roberto, Paul D. Drew, Cynthia J.M. Kane, Rober...> ;Brain, Behavior, and Immunity. 2017 Aug 1
• 41 citations
  Lectin pathway effector enzyme mannan‐binding lectin‐associated serine protease‐2 can activate native complement C3 in absence of C4 and/or C2
  Sadam Yaseen, Gregory A. Demopulos, Thomas Dudler, Munehisa Yabuki, Christi L. Wood, W. Jason Cummings, Larry W. Tjoelker, Teizo Fujita, Steven H. Sacks, Peter Garred,...> ;FASEB Journal. 2017 Feb 10
• 35 citations
  Pioglitazone attenuates the opioid withdrawal and vulnerability to relapse to heroin seeking in rodents.
  Giordano de Guglielmo, Marsida Kallupi, Giulia Scuppa, Gregory Demopulos, George Gaitanaris, Roberto Ciccocioppo> ;Psychopharmacology. 2017 Jan 1
• 44 citations
  Mannan binding lectin-associated serine protease-2 (MASP-2) critically contributes to post-ischemic brain injury independent of MASP-1.
  Franca Orsini, Elvina Chrysanthou, Thomas Dudler, W. Jason Cummings, Minoru Takahashi, Teizo Fujita, Gregory A. Demopulos, Maria Grazia De Simoni, Wilhelm J. Schwaeble> ;Journal of Neuroinflammation. 2016 Aug 30
• 11 citations
  PPARγ activation attenuates opioid consumption and modulates mesolimbic dopamine transmission.
  Giordano de Guglielmo, Miriam Melis, Maria Antonietta De Luca, Marsida Kallupi, Hong Wu Li, Kevin Niswender, Antonio Giordano, Martina Senzacqua, Lorenzo Somaini, Andr...> ;Neuropsychopharmacology. 2015 Mar 1
• 15 citations
  Intracameral phenylephrine and ketorolac injection (OMS302) for maintenance of intraoperative pupil diameter and reduction of postoperative pain in intraocular lens re...
  Richard L. Lindstrom, James C Loden, Thomas R Walters, Steven H Dunn, J. Steven Whitaker, Terry Kim, Demopulos Gregory A, Khiun Tjia> ;Clinical Ophthalmology. 2014 Sep 5
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