GregoryAEwaldMD

Cardiology • Saint Louis, MO

Heart Failure & Transplantation

Professor of Medicine, Interim Chief Cardiovascular Division, Washington University St Louis

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Office
4921 Parkview Pl
Ste 8A
Saint Louis, MO 63110
Phone+1 314-454-7687

Fax+1 314-454-8855
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Education & Training

Washington University/B-JH/SLCH ConsortiumFellowship, Cardiovascular Disease, 1992 - 1997
Washington University/B-JH/SLCH ConsortiumResidency, Internal Medicine, 1989 - 1992
Northwestern University The Feinberg School of MedicineClass of 1989

Certifications & Licensure

IL State Medical License 2020 - 2026
MO State Medical License 1991 - 2025
American Board of Internal Medicine Advanced Heart Failure and Transplant Cardiology
American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

Regional Top Doctor Castle Connolly, 2014
CMS Meaningful Use Stage 1 Certification Allscripts Enterprise EHR, Allscripts, 2012
Fellow (FACC) American College of Cardiology

Clinical Trials

IMAGE: A Comparison of AlloMap Molecular Testing and Traditional Biopsy-based Surveillance for Heart Transplant Rejection Start of enrollment: 2005 Jan 01
Completed
Not Applicable
A Study of Ularitide in the Treatment of Subjects With Acute Decompensated Heart Failure
Withdrawn
Phase 1
Concentrated Saline Infusions and Increased Dietary Sodium With Diuretics for Heart Failure With Kidney Dysfunction Start of enrollment: 2007 Nov 01
Terminated
Phase 2
Decompensation Detection Study Start of enrollment: 2006 Mar 01
Completed
INcrease Of VAgal TonE in CHF Start of enrollment: 2011 Feb 01
Terminated
Phase 3
REGISTRY EVALUATION OF VITAL INFORMATION FOR VADs IN AMBULATORY LIFE Start of enrollment: 2015 Jul 01
Completed
Guiding Evidence Based Therapy Using Biomarker Intensified Treatment Start of enrollment: 2012 Dec 01
Terminated
Not Applicable
Functional Impact of GLP-1 for Heart Failure Treatment (FIGHT) Start of enrollment: 2013 Apr 01
Completed
Phase 2
Cardiovascular Improvements With MV ASV Therapy in Heart Failure Start of enrollment: 2013 Dec 01
Terminated
Not Applicable
Gas Exchange for Predicting Hospital Heart Failure Readmissions Start of enrollment: 2013 Oct 01
Unknown status
Utility of Donor-Derived Cell Free DNA in Association With Gene Expression Profiling Start of enrollment: 2014 Jun 01
Recruiting
Study of High-dose Spironolactone vs. Placebo Therapy in Acute Heart Failure Start of enrollment: 2014 Dec 30
Completed
Phase 2
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Publications & Presentations

PubMed

Characterization of de novo malignancy after orthotopic heart transplantation: single-centre outcomes over 20 years.
Nadia H Bakir, Ioana B Florea, Jordan Phillipps, Joel D Schilling, Marci S Damiano, Gregory A Ewald, Kunal D Kotkar, Akinobu Itoh, Ralph J Damiano Jr, Marc R Moon, Muh...> ;European Journal of Cardio-Thoracic Surgery. 2023 Oct 4
2 citations
The Novel Data Collection and Analytics Tools for Remote Patient Monitoring in Heart Failure (Nov-RPM-HF) Trial: Protocol for a Single-Center Prospective Trial.
Ankit Bhatia, Gregory Ewald, Thomas Maddox> ;JMIR Research Protocols. 2022 Jun 30
1 citations
The bleeding risk treatment paradox at the physician and hospital level: Implications for reducing bleeding in patients undergoing percutaneous coronary intervention.
Amit P. Amin, Nathan Frogge, Hemant Kulkarni, Gene Ridolfi, Gregory A. Ewald, Rachel Miller, Bruce L. Hall, Susan Rogers, Ty J. Gluckman, Jeptha P. Curtis, Frederick A...> ;American Heart Journal. 2022 Jan 1
3 citations
Competing Risks to Transplant in Bridging with Continuous Flow Left Ventricular Assist Devices
Nadia H. Bakir, Michael J. Finnan, Akinobu Itoh, Michael K. Pasque, Gregory A. Ewald, Kunal D. Kotkar, Ralph J. Damiano, Marc R. Moon, Justin Hartupee, Joel D. Schilli...> ;The Annals of Thoracic Surgery. 2021 Nov 19
3 citations
Proinflammatory TH17 cytokine activation, disease severity and outcomes in peripartum cardiomyopathy
Agnes Koczo, Amy Marino, Joseph M Rocco, Gregory A. Ewald, Michael M. Givertz, Navin Rajagopalan, Biykem Bozkurt, Uri Elkayam, Leslie T. Cooper, James D. Fett, Charles...> ;International Journal of Cardiology. 2021 Sep 15
3 citations
A pilot clinical trial of a self-management intervention in patients with a left ventricular assist device
Jesus M. Casida, Marykay A. Pavol, Chakra Budhathoki, Heidi Craddock, Sarah E. Schroeder, Danyelle Hoff, Millie Tiburcio, Gregory A. Ewald> ;Journal of Artificial Organs. 2021 Aug 3
5 citations
Variability in Blood Pressure Assessment in Patients Supported with the HeartMate 3TM.
Jennifer A Cowger, Jerry D. Estep, D. Rinde-Hoffman, Michael M. Givertz, Allen S. Anderson, Daniel Jacoby, Leway Chen, Andreas Brieke, Claudius Mahr, Shelley A. Hall, ...> ;ASAIO Journal. 2021 Jun 25
6 citations
Acute kidney injury post-heart transplant: An analysis of peri-operative risk factors.
Brandon M. Jocher, Joel D. Schilling, Irene Fischer, T. Nakajima, Fei Wan, Y. Tanaka, Gregory A. Ewald, Kunal Kutkar, Muhammad F. Masood, Akinobu Itoh> ;Clinical Transplantation. 2021 Apr 8
3 citations
30 Years of Heart Transplant: Outcomes After Mechanical Circulatory Support From a Single Center.
Michael J. Finnan, Nadia H. Bakir, Akinobu Itoh, Kunal D. Kotkar, Michael K. Pasque, Ralph J. Damiano, Marc R. Moon, Gregory A. Ewald, Joel D. Schilling, Muhammad F. M...> ;The Annals of Thoracic Surgery. 2021 Mar 3
6 citations
Machine Learning Outcome Prediction in Dilated Cardiomyopathy Using Regional Left Ventricular Multiparametric Strain.
Robert M. MacGregor, Aixia Guo, Muhammad F. Masood, Brian P. Cupps, Gregory A. Ewald, Michael K. Pasque, Randi E. Foraker> ;Annals of Biomedical Engineering. 2021 Feb 1
5 citations
Cardiac allograft rejection in the current era of continuous flow left ventricular assist devices
Nadia H. Bakir, Michael J. Finnan, Robert M. MacGregor, Joel D. Schilling, Gregory A. Ewald, Kunal D. Kotkar, Akinobu Itoh, Ralph J. Damiano, Marc R. Moon, Muhammad F....> ;The Journal of Thoracic and Cardiovascular Surgery. 2020 Jul 22
19 citations
Discovery of non-HLA antibodies associated with cardiac allograft rejection and development and validation of a non-HLA antigen multiplex panel: From bench to bedside
Carrie Butler, Michelle J. Hickey, Ning Jiang, Ying Zheng, David W. Gjertson, Qiuheng Zhang, Ping Rao, Gregory A. Fishbein, Martin Cadeiras, Mario C. Deng, Hector L. B...> ;American Journal of Transplantation. 2020 Oct 1
4 citations
Outcomes of Severely Obese Patients Supported by a Centrifugal-Flow Left Ventricular Assist Device
Michael S. Kiernan, Samer S. Najjar, Amanda R. Vest, Emma J. Birks, Nir Uriel, Gregory A. Ewald, Katrin Leadley, Chetan B. Patel> ;Journal of Cardiac Failure. 2020 Feb 1
6 citations
Comorbid Conditions and Health-Related Quality of Life in Ambulatory Heart Failure Patients: REVIVAL (Registry Evaluation of Vital Information for VADs in Ambulatory L...
Thomas Cascino, Michelle M. Kittleson, Anuradha Lala, Josef Stehlik, Maryse Palardy, Salpy V. Pamboukian, Gregory A. Ewald, Maria Mountis, Douglas A. Horstmanshof, Sha...> ;Circulation. Heart Failure. 2020 Jan 1
11 citations
Quality of life and treatment preference for ventricular assist device therapy in ambulatory advanced heart failure: A report from the REVIVAL study.
Josef Stehlik, Maria Mountis, Donald C. Haas, Maryse Palardy, Amrut V. Ambardekar, Jerry D. Estep, Gregory A. Ewald, Stuart D. Russell, Shawn W. Robinson, Ulrich P. Jo...> ;The Journal of Heart and Lung Transplantation. 2020 Jan 1
118 citations
Noninvasive detection of graft injury after heart transplant using donor‐derived cell‐free DNA: A prospective multicenter study
Kiran K. Khush, Jignesh Patel, Sean Pinney, Andrew Kao, R.A. Alharethi, Eugene C. DePasquale, Gregory A. Ewald, Peter Berman, Manreet Kanwar, D. Hiller, J. Yee, Robert...> ;American Journal of Transplantation. 2019 Oct 1
5 citations
Heartland virus infection in a heart transplant recipient from the Heartland
Matthew A. Hevey, Jane A. O’Halloran, Brett W. Jagger, Jennifer E. Staples, Amy J. Lambert, Amanda J. Panella, Olga I. Kosoy, George Turabelidze, David S. Raymer, Greg...> ;Transplant Infectious Disease. 2019 Aug 1
10 citations
Relationship between device acceptance and patient-reported outcomes in Left Ventricular Assist Device (LVAD) recipients
Crispino Tosto, Luigi Adamo, Heidi Craddock, Maria Di Blasi, Rosario Girgenti, Francesco Clemenza, Robert M. Carney, Gregory A. Ewald> ;Scientific Reports. 2019 Jul 25
631 citations
A fully magnetically levitated left ventricular assist device - Final report
, , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , > ;The New England Journal of Medicine. 2019 Mar 17
11 citations
Maternal Obesity Affects Cardiac Remodeling and Recovery in Women with Peripartum Cardiomyopathy.
Esa M. Davis, Gregory A. Ewald, Michael M. Givertz, Navin Rajagopalan, Leslie T. Cooper, Joan Briller, G. Michael Felker, Biykem Bozkurt, Mark H. Drazner, Karen Hanley...> ;American Journal of Perinatology. 2019 Apr 1
10 citations
Advancing the Science of Self-Management in Adults With Long-Term Left Ventricular Assist Devices.
Jesus M. Casida, James E. Aikens, Francis D. Pagani, Gregory A. Ewald, Heidi Craddock, Marykay A. Pavol, Sarah E. Schroeder, James J. Yang> ;Artificial Organs. 2018 Nov 1
55 citations
Remote Monitoring of Patients With Heart Failure: A White Paper From the Heart Failure Society of America Scientific Statements Committee.
Michael G. Dickinson, Larry A. Allen, Nancy A. Albert, Thomas G. DiSalvo, Gregory A. Ewald, Amanda R. Vest, David J. Whellan, Michael R. Zile, Michael M. Givertz> ;Journal of Cardiac Failure. 2018 Oct 1
7 citations
Cerebrovascular Events After Continuous-Flow Left Ventricular Assist Devices.
Pouya Tahsili-Fahadan, David Curfman, Albert A. Davis, Noushin Yahyavi-Firouz-Abadi, Lucia Rivera-Lara, Michael E. Nassif, Shane J. LaRue, Gregory A. Ewald, Allyson R....> ;Neurocritical Care. 2018 Oct 1
450 citations
Two-Year Outcomes with a Magnetically Levitated Cardiac Pump in Heart Failure
Mandeep R. Mehra, Daniel J. Goldstein, Nir Uriel, Joseph C. Cleveland, Melana Yuzefpolskaya, Christopher T. Salerno, Mary Norine Walsh, Carmelo A. Milano, Chetan B. Pa...> ;The New England Journal of Medicine. 2018 Mar 11
4 citations
Internal driveline damage under the costal margin several years after HeartMate II implant: a series of three cases.
Mitsugu Ogawa, Muhammad F. Masood, Gregory A. Ewald, Justin M. Vader, Shane J. LaRue, Allen Cheng, Keki R. Balsara, Akinobu Itoh> ;Journal of Artificial Organs. 2018 Mar 3
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Journal Articles

Non‐Invasive Detection of Graft Injury After Heart Transplantation Using Donor‐Derived Cell‐Free DNA: A Prospective Multi‐Center Study
Gregory Ewald, Jon Kobashigawa, Kiran K Khush, Jignesh Patel, Eugene DePasquale, Sean Pinney, American journal of transplantation
Remote Monitoring of Patients with Heart Failure: A White Paper from the Heart Failure Society of America Scientific Statements Committee
Gregory A Ewald, Amanda R Vest, David J Whellan, Michael R Zile, Michael M Givertz, Journal of Cardiac Failure
Increased Prevalence of Cardiac Allograft Donors with Improved LV Systolic Function Utilizing an Out-of-Hospital Treatment and Recovery Center
Justin Hartupee, Shane Larue, Justin Vader, Gregory Ewald, Journal of Cardiac Failure

Lectures

Cardiology Update
Washington University School of Medicine, Saint Louis, Missouri - 6/9/2012

Authored Content

Remote Monitoring of Patients with Heart Failure: A White Paper from the Heart Failure Society of America Scientific Statements CommitteeOctober 2018
Increased Prevalence of Cardiac Allograft Donors with Improved LV Systolic Function Utilizing an Out-of-Hospital Treatment and Recovery CenterSeptember 2018