GregoryJayMD

PubMed

• Recombinant human proteoglycan 4 lowers inflammation and atherosclerosis susceptibility in female low-density lipoprotein receptor knockout mice.
  Menno Hoekstra, Olga S C Snip, Philip Janusz, Mireia N A Bernabé Kleijn, Edward R Truitt 3rd, Benjamin D Sullivan, Tannin A Schmidt, Miranda Van Eck, Gregory D Jay> ;The Journal of Physiology. 2024 May 1
• Dissolvable Immunomodulatory Microneedles for Treatment of Skin Wounds.
  Pejman Ghelich, Mohamadmahdi Samandari, Alireza Hassani Najafabadi, Adam Tanguay, Jacob Quint, Nikhil Menon, Delaram Ghanbariamin, Farnoosh Saeedinejad, Fatemeh Alipan...> ;Advanced Healthcare Materials. 2024 Feb 1
• Scale-Dependent Rheology of Synovial Fluid Lubricating Macromolecules.
  Martin-Alarcon, L., Govedarica, A., Ewoldt, R., Bryant, S., Schmidt, T., Trifkovic, M., Jay, G.> ;Small. 2023 Dec 31
• Plasma proteoglycan 4: a novel biomarker for acute lung injury after pediatric cardiac surgery.
  Ahmed Asfari, Erica A Doyle, Gregory D Jay, Natalia Aristizabal, Ananya Manchikalapati, A K M Fazlur Rahman, Kristal M Hock, Santiago Borasino, Namasivayam Ambalavanan...> ;Translational Pediatrics. 2023 Sep 18
• 1 citations
  A structural and functional comparison between two recombinant human lubricin proteins: Recombinant human proteoglycan-4 (rhPRG4) vs ECF843.
  Nikhil G Menon, Adam P Tanguay, Libo Zhou, Ling X Zhang, Cedric E Bobst, Mingyu Han, Mallika Ghosh, George W Greene, Alix Deymier, Benjamin D Sullivan, Yupeng Chen, Gr...> ;Experimental Eye Research. 2023 Oct 1
• Evaluation of microMend wound closure device in repairing skin lacerations.
  Tarek Nizami, Francesca Beaudoin, Selim Suner, Adam Aluisio, Reena A Bhatt, Gregory D Jay> ;Emergency Medicine Journal. 2023 Aug 1
• 8 citations
  Tryptase β regulation of joint lubrication and inflammation via proteoglycan-4 in osteoarthritis.
  Nabangshu Das, Luiz G N de Almeida, Afshin Derakhshani, Daniel Young, Kobra Mehdinejadiani, Paul Salo, Alexander Rezansoff, Gregory D Jay, Christian P Sommerhoff, Tann...> ;Nature Communications. 2023 Apr 6
• 4 citations
  Recombinant Human Proteoglycan 4 (rhPRG4) Downregulates TNFα-Stimulated NFκB Activity and FAT10 Expression in Human Corneal Epithelial Cells.
  Nikhil G Menon, Yasir Suhail, Ruchi Goyal, Wenqiang Du, Adam P Tanguay, Gregory D Jay, Mallika Ghosh, Kshitiz, Tannin A Schmidt> ;International Journal of Molecular Sciences. 2022 Oct 22
• 1 citations
  Noncovalent hyaluronan crosslinking by TSG-6: Modulation by heparin, heparan sulfate, and PRG4.
  Yun Jin Ashley Sin, Rebecca MacLeod, Adam P Tanguay, Andrew Wang, Olivia Braender-Carr, Teraesa M Vitelli, Gregory D Jay, Tannin A Schmidt, Mary K Cowman> ;Frontiers in Molecular Biosciences. 2022 Jan 1
• 4 citations
  Truncated lubricin glycans in osteoarthritis stimulate the synoviocyte secretion of VEGFA, IL-8, and MIP-1: Interplay between-linked glycosylation and inflammatory cyt...
  Shan Huang, Kristina A Thomsson, Chunsheng Jin, Henrik Ryberg, Nabangshu Das, André Struglics, Ola Rolfson, Lena I Björkman, Thomas Eisler, Tannin A Schmidt, Gregory D...> ;Frontiers in Molecular Biosciences. 2022 Jan 1
• 5 citations
  Efficient Detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) from Exhaled Breath.
  Chaorui Duan, Luke Buerer, Jing Wang, Samuel Kaplan, Gavin Sabalewski, Gregory D. Jay, Sean F. Monaghan, Andrea E. Arena, William G. Fairbrother> ;The Journal of Molecular Diagnostics. 2021 Sep 29
• 17 citations
  Proteoglycan-4 is an essential regulator of synovial macrophage polarization and inflammatory macrophage joint infiltration.
  Marwa Qadri, Gregory D. Jay, Ling X. Zhang, Tannin A. Schmidt, Jennifer Totonchy, Khaled A. Elsaid> ;Arthritis Research & Therapy. 2021 Sep 14
• 11 citations
  Prediction of anemia and estimation of hemoglobin concentration using a smartphone camera.
  Selim Suner, James Rayner, İbrahim Ulaş Özturan, Geoffrey Hogan, Caroline P. Meehan, Alison B. Chambers, Janette Baird, Gregory D. Jay> ;Plos One. 2021 Jul 14
• 15 citations
  Proteoglycan 4 (PRG4) expression and function in dry eye associated inflammation.
  Nikhil G. Menon, Ruchi Goyal, Carolina Lema, Paige S. Woods, Adam P. Tanguay, Alyssa A. Morin, Nabangshu Das, Gregory D. Jay, Roman Krawetz, Antoine Dufour, Linda H. S...> ;Experimental Eye Research. 2021 May 25
• 2 citations
  The role of synovial fluid constituents in the lubrication of collagen-glycosaminoglycan scaffolds for cartilage repair.
  Austyn Matheson, Eamon J. Sheehy, Gregory D. Jay, W Michael Scott, Fergal J. O'Brien, Tannin A. Schmidt> ;Journal of the Mechanical Behavior of Biomedical Materials. 2021 Mar 12
• Author Correction: Cathepsin g Degrades Both Glycosylated and Unglycosylated Regions of Lubricin, a Synovial Mucin
  Shan Huang, Kristina A. Thomsson, Chunsheng Jin, Sally Alweddi, André Struglics, Ola Rolfson, Lena Björkman, Sebastian Kalamajski, Tannin A. Schmidt, Gregory D. Jay, R...> ;Scientific Reports. 2021 Feb 15
• 1 citations
  Correction to: Proteoglycan-4 is an essential regulator of synovial macrophage polarization and inflammatory macrophage joint infiltration.
  Marwa Qadri, Gregory D. Jay, Ling X. Zhang, Tannin A. Schmidt, Jennifer Totonchy, Khaled A. Elsaid> ;Arthritis Research & Therapy. 2021 Jan 1
• 22 citations
  Proteomics Analysis of Tears and Saliva From Sjogren's Syndrome Patients.
  Nabangshu Das, Nikhil G Menon, Luiz G N de Almeida, Paige S Woods, Miriam L Heynen, Gregory D Jay, Barbara Caffery, Lyndon Jones, Roman Krawetz, Tannin A Schmidt, Anto...> ;Frontiers in Pharmacology. 2021 Jan 1
• 9 citations
  Recombinant Human Proteoglycan 4 Regulates Phagocytic Activation of Monocytes and Reduces IL-1β Secretion by Urate Crystal Stimulated Gout PBMCs.
  Sandy ElSayed, Gregory D Jay, Ralph Cabezas, Marwa Qadri, Tannin A Schmidt, Khaled A Elsaid> ;Frontiers in Immunology. 2021 Jan 1
• 1 citations
  The Effect of Intense Exercise on Equine Serum Proteoglycan-4/Lubricin.
  Austyn Matheson, Suresh C. Regmi, Gregory D. Jay, Tannin A. Schmidt, W Michael Scott> ;Frontiers in Veterinary Science. 2020 Dec 16
• 2 citations
  Titration of Parameters in Shared Ventilation With a Portable Ventilator.
  Sakina H. Sojar, William Bortcosh, Paul C Decerbo, Esther H. Chung, Carolyn Lavita, Gregory D. Jay> ;Respiratory Care. 2021 Mar 23
• 9 citations
  Proteoglycan 4 Reduces Neuroinflammation and Protects the Blood-Brain Barrier after Traumatic Brain Injury.
  Marissa Bennett, Andrea T. Chin, Hyung Jin Lee, Emma Morales Cestero, Nathalie Strazielle, Jean-François Ghersi-Egea, Steven W. Threlkeld, Tannin A. Schmidt, Holly A. ...> ;Journal of Neurotrauma. 2021 Jan 29
• 2 citations
  Decrease of core 2 O- glycans on synovial lubricin in osteoarthritis reduces galectin-3 mediated crosslinking
  Sarah A. Flowers, Kristina A. Thomsson, Liaqat Ali, Shan Huang, Yolanda H Mthembu, Suresh C. Regmi, Jan Holgersson, Tannin A. Schmidt, Ola Rolfson, Lena Björkman, Mart...> ;The Journal of Biological Chemistry. 2020 Nov 20
• 3 citations
  Recombinant Human Proteoglycan-4 Mediates Interleukin-6 Response in Both Human and Mouse Endothelial Cells Induced Into a Sepsis Phenotype.
  Holly A. Richendrfer, Mitchell M. Levy, Khaled A. Elsaid, Tannin A. Schmidt, Ling Zhang, Ralph Cabezas, Gregory D. Jay> ;Critical Care Explorations. 2020 Jun 10
• 25 citations
  Proteoglycan-4 regulates fibroblast to myofibroblast transition and expression of fibrotic genes in the synovium.
  Marwa Qadri, Gregory D. Jay, Ling X. Zhang, Holly Richendrfer, Tannin A. Schmidt, Khaled A. Elsaid> ;Arthritis Research & Therapy. 2020 May 13
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Journal Articles

• Recombinant Human Proteoglycan-4 Reduces Phagocytosis of Urate Crystals and Downstream Nuclear Factor Kappa B and Inflammasome Activation and Production of Cytokines a...  
  Gregory D Jay, Anthony M Reginato, BioMed Central