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Office
15th Floor, South Tower, Perelman Center for Advanced Medicine
3400 Civic Center Boulevard
Philadelphia, PA 19104Phone+1 215-662-3487- Is this information wrong?
Summary
- I am a board-certified neurosurgeon whose clinical practice encompasses epilepsy surgery, deep brain stimulation, and the resection of brain tumors in and around eloquent brain. I also run a laboratory focused on rebuilding brain circuitry after injury and translating CNS-based gene therapies.
Education & Training
University of Pennsylvania Health SystemResidency, Neurological Surgery, 2007 - 2014
Perelman School of Medicine at the University of PennsylvaniaClass of 2007
Harvard UniversityAB, Biochemical Studies, Summa Cum Laude, 1998 - 2002
Certifications & Licensure
NJ State Medical License 2014 - 2025
PA State Medical License 2010 - 2024- American Board of Neurological Surgery Neurological Surgery
Publications & Presentations
PubMed
- 21 citationsStructural and functional integration of human forebrain organoids with the injured adult rat visual system.Dennis Jgamadze, James T Lim, Zhijian Zhang, Paul M Harary, James Germi, Kobina Mensah-Brown, Christopher D Adam, Ehsan Mirzakhalili, Shikha Singh, Jiahe Ben Gu, Rache...> ;Cell Stem Cell. 2023 Feb 2
- 6 citationsAxonal Tract Reconstruction Using a Tissue-Engineered Nigrostriatal Pathway in a Rat Model of Parkinson's Disease.Laura A Struzyna, Kevin D Browne, Justin C Burrell, Wisberty J Gordián Vélez, Kathryn L Wofford, Hilton M Kaplan, N Sanjeeva Murthy, H Isaac Chen, John E Duda, Rodrigo...> ;International Journal of Molecular Sciences. 2022 Nov 12
- 7 citationsTissue-engineered grafts exploit axon-facilitated axon regeneration and pathway protection to enable recovery after 5-cm nerve defects in pigs.Douglas H Smith, Justin C Burrell, Kevin D Browne, Kritika S Katiyar, Mindy I Ezra, John L Dutton, Joseph P Morand, Laura A Struzyna, Franco A Laimo, H Isaac Chen, Joh...> ;Science Advances. 2022 Nov 4
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Authored Content
- The Effect of Underlying Liver Disease on Perioperative Outcomes Following Craniotomy for Tumor: An ACS-NSQIP AnalysisApril 2018
Press Mentions
Human Brain Organoids Integrated into Rats to Repair Injuries in Their Visual Processing SystemsFebruary 3rd, 2023
Grant Support
- Chronic versus acute transplantation of neural tissue for TBI-induced cortical injuriesNINDS/NIH2021–2026
Professional Memberships
- Member
- American Epilepsy SocietyMember
- American Society of Stereotactic and Functional NeurosurgeryMember
- Congress of Neurological SurgeonsMember
- International Society for Stem Cell ResearchMember
- Society for NeuroscienceMember
Other Languages
- Chinese (Mandarin)
Hospital Affiliations
Philadelphia Veterans Affairs Medical CenterPhiladelphia, Pennsylvania
Hospital of the University of PennsylvaniaPhiladelphia, Pennsylvania- Penn Presbyterian Medical CenterPhiladelphia, Pennsylvania
Pennsylvania HospitalPhiladelphia, Pennsylvania
Children's Hospital of PhiladelphiaPhiladelphia, Pennsylvania
External Links
- Penn Neurosurgeryhttps://www.pennmedicine.org/departments-and-centers/neurosurgery
- Chen Labhttps://www.med.upenn.edu/chenlab/
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