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15th Floor, South Tower, Perelman Center for Advanced Medicine3400 Civic Center BoulevardPhiladelphia, PA 19104
Phone+1 215-662-3487
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Summary
- I am a board-certified neurosurgeon whose clinical practice encompasses epilepsy surgery, deep brain stimulation, and the resection of brain tumors in and around eloquent brain. I also run a laboratory focused on rebuilding brain circuitry after injury and translating CNS-based gene therapies.
Education & Training
University of Pennsylvania Health SystemResidency, Neurological Surgery, 2007 - 2014
Perelman School of Medicine at the University of PennsylvaniaClass of 2007
Harvard UniversityAB, Biochemical Studies, Summa Cum Laude, 1998 - 2002
Certifications & Licensure
NJ State Medical License 2014 - 2027
PA State Medical License 2010 - 2026
American Board of Neurological Surgery Neurological Surgery
Awards, Honors, & Recognition
- CMS Meaningful Use Stage 1 Certification Beacon Oncology 2014 Certified Module, Epic Systems Corporation, 2016
- CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory 2014 Certified EHR Suite, Epic Systems Corporation, 2016
Publications & Presentations
PubMed
- Arousal state modulates human hippocampal ripples.Elizabeth M Siefert, Yvonne Y Chen, Kathryn A Davis, Han-Chiao I Chen, Anna C Schapiro
Biorxiv. 2026-06-28 - Thalamus: a real-time system for synchronized, closed-loop multimodal behavioral and electrophysiological data capture.Jarl Haggerty, Qasim Qureshi, Ellie D Gabriel, Pedro Glb Borges, Pierce Davis
Communications Engineering. 2026-03-26 - Reducing artifacts during human intracranial electrical stimulation by separating current return from recording ground.Denise Oswalt, Michael S Beauchamp, Han-Chiao Isaac Chen, Daniel Yoshor
Brain Stimulation. 2025-10-30
Authored Content
- The Effect of Underlying Liver Disease on Perioperative Outcomes Following Craniotomy for Tumor: An ACS-NSQIP AnalysisApril 2018
Press Mentions
Human Brain Organoids Integrated into Rats to Repair Injuries in Their Visual Processing SystemsFebruary 3rd, 2023
Grant Support
- Research Training Program in Disease-Oriented Neuroscience (R25)UNIVERSITY OF PENNSYLVANIA2009–2029
- Chronic Versus Acute Transplantation of Neural Tissues for TBI-Induced Cortical InjuriesUNIVERSITY OF PENNSYLVANIA2021–2026
- Chronic versus acute transplantation of neural tissue for TBI-induced cortical injuriesNINDS/NIH2021–2026
Professional Memberships
- Member
- American Epilepsy SocietyMember
- American Society of Stereotactic and Functional NeurosurgeryMember
- Congress of Neurological SurgeonsMember
- International Society for Stem Cell ResearchMember
Other Languages
- Chinese (Mandarin)
External Links
- Penn Neurosurgeryhttps://www.pennmedicine.org/departments-and-centers/neurosurgery
- Chen Labhttps://www.med.upenn.edu/chenlab/
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