HansellStedmanMD

PubMed

• Confronting complexity in the design and conduct of high-risk rare disease clinical trials.
  Hansell H Stedman> ;Molecular Therapy. 2023 May 3
• 4 citations
  Challenges at the Crossroads: Myopathy Trials in 2020 Hindsight.
  Christopher D. Greer, Benjamin W. Kozyak, Hansell H. Stedman> ;Molecular Therapy. 2021 Jan 14
• 48 citations
  Broader Implications of Progressive Liver Dysfunction and Lethal Sepsis in Two Boys following Systemic High-Dose AAV.
  Leon Morales, Yuva Gambhir, Jean Bennett, Hansell H. Stedman> ;Molecular Therapy. 2020 Jul 16
• 44 citations
  Non-immunogenic utrophin gene therapy for the treatment of muscular dystrophy animal models.
  Yafeng Song, Leon Morales, Alock Malik, Andrew F. Mead, Christopher D. Greer, Marilyn A. Mitchell, Mihail Petrov, Leonard T. Su, Margaret E Choi, Shira T. Rosenblum, X...> ;Nature Medicine. 2019 Oct 7
• 5 citations
  Mechanism of Deletion Removing All Dystrophin Exons in a Canine Model for DMD Implicates Concerted Evolution of X Chromosome Pseudogenes
  D. Jake VanBelzen, Alock Malik, Paula S. Henthorn, Joe N. Kornegay, Hansell H. Stedman> ;Molecular Therapy. Methods & Clinical Development. 2017 Mar 17
• 3 citations
  Suite of Clinically Relevant Functional Assays to Address Therapeutic Efficacy and Disease Mechanism in the Dystrophic mdx Mouse
  Yafeng Song, Shira T. Rosenblum, Leon Morales, Mihail Petrov, Christopher D. Greer, Samantha Globerman, Hansell H. Stedman> ;Journal of Applied Physiology. 2017 Mar 1
• 10 citations
  Perspectives on best practices for gene therapy programs.
  Thomas R. Cheever, Dale Berkley, Serge Braun, Robert H. Brown, Barry J. Byrne, Jeffrey S. Chamberlain, Valerie Cwik, Dongsheng Duan, Howard J. Federoff, Katherine A. H...> ;Human Gene Therapy. 2015 Feb 5
• 23 citations
  Diaphragm remodeling and compensatory respiratory mechanics in a canine model of Duchenne muscular dystrophy.
  Andrew F. Mead, Mihail Petrov, Alock Malik, Marilyn A. Mitchell, Martin K. Childers, Janet R. Bogan, G. Seidner, Joe N. Kornegay, Hansell H. Stedman> ;Journal of Applied Physiology. 2014 Apr 1
• 23 citations
  Cardiac surgical delivery of the sarcoplasmic reticulum calcium ATPase rescues myocytes in ischemic heart failure.
  Anthony S. Fargnoli, Michael G. Katz, Charles Yarnall, Alice Isidro, Michael Petrov, Nury Steuerwald, Sriparna Ghosh, Kyle C. Richardville, Richard Hillesheim, Richard...> ;The Annals of Thoracic Surgery. 2013 Aug 1
• 1 citations
  Signs of Progress in Gene Therapy for Muscular Dystrophy Also Warrant Caution
  Hansell H. Stedman, Barry J. Byrne> ;Molecular Therapy. 2012 Feb 1
• 6 citations
  A Pharmacokinetic Analysis of Molecular Cardiac Surgery With Recirculation Mediated Delivery of βARKct Gene Therapy: Developing a Quantitative Definition of the Therap...
  Anthony S. Fargnoli, Michael G. Katz, Charles Yarnall, Marina Sumaroka, Hansell H. Stedman, Joseph J. Rabinowitz, Walter J. Koch, Charles R. Bridges> ;Journal of Cardiac Failure. 2011 Aug 1
• 52 citations
  Myocardial gene delivery using molecular cardiac surgery with recombinant adeno-associated virus vectors in vivo.
  Jennifer D. White, Danielle M. Thesier, JaBaris D. Swain, Michael G. Katz, Catherine E. Tomasulo, A Henderson, Lili Wang, Charles Yarnall, Anthony S. Fargnoli, Marina ...> ;Gene Therapy. 2011 Jan 13
• 5 citations
  A Translatable, Closed Recirculation System for AAV6 Vector-Mediated Myocardial Gene Delivery in the Large Animal
  JaBaris D. Swain, Michael G. Katz, Jennifer D. White, Danielle M. Thesier, Armen Henderson, Hansell H. Stedman, Charles R. Bridges> ;Methods in Molecular Biology. 2011 Jan 1
• 4 citations
  Gene transfer to muscle from the isolated regional circulation.
  Mihail Petrov, Alock Malik, Andrew F. Mead, Charles R. Bridges, Hansell H. Stedman> ;Methods in Molecular Biology. 2011 Jan 1
• 56 citations
  Safety of AAV Factor IX Peripheral Transvenular Gene Delivery to Muscle in Hemophilia B Dogs
  Virginia Haurigot, Federico Mingozzi, George Buchlis, Daniel J. Hui, Yifeng Chen, Etiena Basner-Tschakarjan, Valder R. Arruda, Antoneta Radu, Helen W. G. Franck, J. Fr...> ;Molecular Therapy. 2010 Jul 1
• 86 citations
  Peripheral transvenular delivery of adeno-associated viral vectors to skeletal muscle as a novel therapy for hemophilia B
  Valder R. Arruda, Hansell H. Stedman, Virginia Haurigot, George Buchlis, Stefano Baila, Patricia Favaro, Yifeng Chen, Helen W. G. Franck, Shangzhen Zhou, J. Fraser Wri...> ;Blood. 2010 Jun 10
• 30 citations
  Cardiac gene therapy: optimization of gene delivery techniques in vivo.
  Michael G. Katz, JaBaris D. Swain, Jennifer D. White, David W. Low, Hansell H. Stedman, Charles R. Bridges> ;Human Gene Therapy. 2010 Mar 15
• Room for thought: of mutations, muscle, "fitness," and the human condition.
  Hansell H. Stedman> ;Proceedings of the American Philosophical Society. 2009 Sep 1
• 113 citations
  Limb-girdle muscular dystrophy in the United States.
  Steven A. Moore, Christopher Shilling, Steven Westra, Cheryl Wall, Matthew Wicklund, Catherine A. Stolle, Charlotte A. Brown, Daniel E. Michele, F. Piccolo, Thomas L. ...> ;Journal of Neuropathology and Experimental Neurology. 2006 Oct 1
• 37 citations
  Efficient myocyte gene delivery with complete cardiac surgical isolation in situ.
  Charles R. Bridges, Kapil Gopal, David E. Holt, Charles Yarnall, Steven G. Cole, Rochelle B. Anderson, Xiaoqing Yin, Anthony J. Nelson, Benjamin W. Kozyak, Zhonglin Wa...> ;The Journal of Thoracic and Cardiovascular Surgery. 2005 Nov 1
• 60 citations
  Uniform Scale-Independent Gene Transfer to Striated Muscle After Transvenular Extravasation of Vector
  Leonard T. Su, Kapil Gopal, Zhonglin Wang, Xiaoqing Yin, Anthony J. Nelson, Benjamin W. Kozyak, James M. Burkman, Marilyn A. Mitchell, David W. Low, Charles R. Bridges...> ;Circulation. 2005 Sep 20
• 119 citations
  Regional intravascular delivery of AAV-2-F.IX to skeletal muscle achieves long-term correction of hemophilia B in a large animal model.
  Valder R. Arruda, Hansell H. Stedman, Timothy C. Nichols, Mark E. Haskins, Matthew Nicholson, Roland W. Herzog, Linda B. Couto, Katherine A. High> ;Blood. 2005 May 1
• 209 citations
  Myosin gene mutation correlates with anatomical changes in the human lineage
  Hansell H. Stedman, Benjamin W. Kozyak, Anthony J. Nelson, Danielle M. Thesier, Leonard T. Su, David W. Low, Charles R. Bridges, Joseph B. Shrager, Nancy Minugh-Purvis...> ;Nature. 2004 Mar 25
• 37 citations
  Myosin heavy chain and physiological adaptation of the rat diaphragm in elastase-induced emphysema
  Dong Kwan Kim, Jianliang Zhu, Benjamin W. Kozyak, James M. Burkman, Neal A. Rubinstein, Edward B. Lankford, Hansell H. Stedman, Taitan Nguyen, Sanford Levine, Joseph B...> ;Respiratory Research. 2003 Feb 17
• 9 citations
  Inspiratory loading does not accelerate dystrophy in mdx mouse diaphragm: implications for regenerative therapy.
  Alexander S. Krupnick, Jianliang Zhu, Taitan Nguyen, Daniel Kreisel, Keki R. Balsara, Edward B. Lankford, Charles C. Clark, Sanford Levine, Hansell H. Stedman, Joseph ...> ;Journal of Applied Physiology. 2003 Feb 1
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