HaobinChenMD(He/Him)

PubMed

• Proteomics: A new dimension to decode small cell lung cancer.
  Chen, H., Drapkin, B., Minna, J.> ;Cell. 2024 Jan 4
• 1 citations
  Health Insurance Coverage and Survival Outcomes among Nasopharyngeal Carcinoma Patients: A SEER Retrospective Analysis.
  Ashley Diaz, Daniel Bujnowski, Haobin Chen, Keaton Pendergrast, Peleg Horowitz, Paramita Das, Christopher Roxbury> ;Journal of Neurological Surgery. Part B, Skull Base. 2023 Jun 1
• Cigarette Smoke Enhances the Malignant Phenotype of Esophageal Adenocarcinoma Cells by Disrupting a Repressive Regulatory Interaction Between miR-145 and LOXL2.
  Sichuan Xi, Shakirat Oyetunji, Haitao Wang, Said Azoury, Yi Liu, Shih-Hsin Hsiao, Mary Zhang, Shamus R Carr, Chuong D Hoang, Haobin Chen, David S Schrump> ;Laboratory Investigation; a Journal of Technical Methods and Pathology. 2023 Apr 1
• 8 citations
  BET Inhibitors Target the SCLC-N Subtype of Small-Cell Lung Cancer by Blocking NEUROD1 Transactivation.
  Haobin Chen, Lisa Gesumaria, Young-Kwon Park, Trudy G Oliver, Dinah S Singer, Kai Ge, David S Schrump> ;Molecular Cancer Research. 2023 Feb 1
• Joint-Predominant Rheumatic Complications of Immune Checkpoint Inhibitor Therapy in Patients with Thymic Epithelial Tumors.
  Cristina Mullenix, Madison Ballman, Haobin Chen, Shannon Swift, Meredith J McAdams, Yo-Ting Tsai, Renee N Donahue, Trina Poretta, Sarthak Gupta, Patrick J Loehrer, Jef...> ;The Oncologist. 2022 Apr 5
• 33 citations
  Molecular Subtypes of Primary SCLC Tumors and Their Associations With Neuroendocrine and Therapeutic Markers.
  Song Qu, Patricia Fetsch, Anish Thomas, Yves Pommier, David S. Schrump, Markku Miettinen, Haobin Chen> ;Journal of Thoracic Oncology. 2021 Sep 15
• 2 citations
  Hookah Smoke Mediates Cancer-Associated Epigenomic and Transcriptomic Signatures in Human Respiratory Epithelial Cells
  Yin Xiong, Sichuan Xi, Sudheer Kumar Gara, Jigui Shan, James Gao, Mary Zhang, Vivek Shukla, Rui-Hong Wang, Chuong D. Hoang, Haobin Chen, David S. Schrump> ;JTO Clinical and Research Reports. 2021 May 8
• 15 citations
  Long, Noncoding RNA Dysregulation in Glioblastoma.
  Patrick A. DeSouza, Xuan Qu, Hao Chen, Bhuvic Patel, Christopher G. Maher, Albert H. Kim> ;Cancers. 2021 Mar 31
• 16 citations
  UHRF1 is a Novel Druggable Epigenetic Target in Malignant Pleural Mesothelioma
  Emily S. Reardon, Vivek Shukla, Sichuan Xi, Sudheer Kumar Gara, Yi Liu, David M. Straughan, Mary Zhang, Julie A. Hong, Eden C. Payabyab, Anju Kumari, William G. Richar...> ;Journal of Thoracic Oncology. 2021 Jan 1
• 15 citations
  Genotype of CDC73 germline mutation determines risk of parathyroid cancer.
  Yulong Li, Jian-Hua Zhang, Poorni R. Adikaram, James Welch, Bin Guan, Lee S. Weinstein, Haobin Chen, William F. Simonds> ;Endocrine-Related Cancer. 2020 Sep 1
• 80 citations
  Clonal Evolution and Heterogeneity of Osimertinib Acquired Resistance Mechanisms in EGFR Mutant Lung Cancer.
  Nitin Roper, Anna-Leigh Brown, Jun Wei, Svetlana Pack, Christopher Trindade, Chul Kim, Olivia Restifo, Shaojian Gao, Sivasish Sindiri, Farid Rashidi Mehrabadi, Rajaa E...> ;Cell Reports. Medicine. 2020 Apr 21
• 94 citations
  Phase I Study of ATR Inhibitor M6620 in Combination With Topotecan in Patients With Advanced Solid Tumors.
  Anish Thomas, Christophe E. Redon, Linda Sciuto, Emerson Padiernos, Jiuping Ji, Min-Jung Lee, Akira Yuno, Sunmin Lee, Yiping Zhang, Lan Tran, William H. Yutzy, Arun Ra...> ;Journal of Clinical Oncology. 2017 Dec 18
• Nickel ions inhibit histone demethylase JMJD1A and DNA repair enzyme ABH2 by replacing the ferrous iron in the catalytic centers.
  Haobin Chen, Nitai Charan Giri, Ronghe Zhang, Kenichi Yamane, Yi Zhang, Michael Maroney, Max Costa> ;The Journal of Biological Chemistry. 2017 Jun 23
• 16 citations
  X-ray absorption spectroscopy structural investigation of early intermediates in the mechanism of DNA repair by human ABH2
  Nitai Charan Giri, Hong Sun, Haobin Chen, Max Costa, Michael J. Maroney> ;Biochemistry. 2011 Jun 7
• 66 citations
  Hypoxia and nickel inhibit histone demethylase JMJD1A and repress Spry2 expression in human bronchial epithelial BEAS-2B cells
  Haobin Chen, Thomas Kluz, Ronghe Zhang, Max Costa> ;Carcinogenesis. 2010 Dec 1
• 21 citations
  Roles of MAPK pathway activation during cytokine induction in BEAS-2B cells exposed to fine World Trade Center (WTC) dust.
  Shang Wang, Colette Prophete, Joleen M. Soukup, Lung Chi Chen, Max Costa, Andrew J. Ghio, Qingshan Qu, Mitchell D. Cohen, Haobin Chen> ;Journal of Immunotoxicology. 2010 Nov 17
• 33 citations
  Phase II study of darinaparsin in patients with advanced hepatocellular carcinoma
  Jennifer Wu, Charles A. Henderson, Lynn G. Feun, Peter J. Van Veldhuizen, Philip J. Gold, Hui Zheng, Theresa Ryan, Lawrence S. Blaszkowsky, Haobin Chen, Max Costa, Bar...> ;Investigational New Drugs. 2010 Oct 1
• 34 citations
  Effects of cellular iron deficiency on the formation of vascular endothelial growth factor and angiogenesis.
  Jonathan Eckard, Jisen Dai, Jing Wu, Jinlong Jian, Qing Yang, Haobin Chen, Max Costa, Krystyna Frenkel, Xi Huang> ;Cancer Cell International. 2010 Aug 19
• 97 citations
  Hypoxia induces trimethylated H3 lysine 4 by inhibition of JARID1A demethylase.
  Xue Zhou, Hong Sun, Haobin Chen, Jiri Zavadil, Thomas Kluz, Adriana Arita, Max Costa> ;Cancer Research. 2010 May 15
• 18 citations
  Nickel ions inhibit histone demethylase JMJD1A and DNA repair enzyme ABH2 by replacing the ferrous iron in the catalytic centers.
  Haobin Chen, Nitai Charan Giri, Ronghe Zhang, Kenichi Yamane, Yi Zhang, Michael Maroney, Max Costa> ;The Journal of Biological Chemistry. 2010 Mar 5
• 97 citations
  Modulation of histone methylation and MLH1 gene silencing by hexavalent chromium.
  Hong Sun, Xue Zhou, Haobin Chen, Qin Li, Max Costa> ;Toxicology and Applied Pharmacology. 2009 Jun 15
• 56 citations
  Iron- and 2-oxoglutarate-dependent dioxygenases: an emerging group of molecular targets for nickel toxicity and carcinogenicity.
  Haobin Chen, Max Costa> ;Biometals. 2009 Feb 1
• 65 citations
  Phosphorylation of H3S10 blocks the access of H3K9 by specific antibodies and histone methyltransferase. Implication in regulating chromatin dynamics and epigenetic in...
  Qing Duan, Haobin Chen, Max Costa, Wei Dai> ;The Journal of Biological Chemistry. 2008 Nov 28
• 149 citations
  Arsenite alters global histone H3 methylation.
  Xue Zhou, Hong Sun, Thomas P. Ellen, Haobin Chen, Max Costa> ;Carcinogenesis. 2008 Sep 1
• 48 citations
  Dietary chromium and nickel enhance UV-carcinogenesis in skin of hairless mice
  Ahmed N. Uddin, Fredric J. Burns, Toby G. Rossman, Haobin Chen, Thomas Kluz, Max Costa> ;Toxicology and Applied Pharmacology. 2007 Jun 15
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