HarrisonMichaelPenroseMDPhD

PubMed

• 1 citations
  The ClC-2 Chloride Channel Activator, Lubiprostone, Improves Intestinal Barrier Function in Biopsies from Crohn's Disease but Not Ulcerative Colitis Patients.
  Young Su Park, Sang Bum Kang, Ronald R Marchelletta, Harrison M Penrose, Roos Ruiter-Visser, Barbara Jung, Michael J Docherty, Brigid S Boland, William J Sandborn, Dec...> ;Pharmaceutics. 2023 Mar 2
• 5 citations
  Trends in the Incidence of Early-Onset Colorectal Adenocarcinoma Among Black and White US Residents Aged 40 to 49 Years, 2000-2017.
  Eric M. Montminy, Meijiao Zhou, Lauren Maniscalco, Harrison M. Penrose, Timothy Yen, Swati G. Patel, Xiao-Cheng Wu, Jordan J Karlitz> ;JAMA Network Open. 2021 Nov 1
• 14 citations
  Ulcerative colitis immune cell landscapes and differentially expressed gene signatures determine novel regulators and predict clinical response to biologic therapy.
  Harrison M. Penrose, Rida Iftikhar, Morgan E. Collins, Eman A. Toraih, Emmanuelle Ruiz, Nathan Ungerleider, Hani Nakhoul, Erik F. Flemington, Emad Kandil, Shamita B. S...> ;Scientific Reports. 2021 Apr 27
• 1 citations
  STAT1 regulates interferon-γ-induced angiotensinogen and MCP-1 expression in a bidirectional manner in primary cultured mesangial cells.
  Harrison M. Penrose, Akemi Katsurada, Kayoko Miyata, Maki Urushihara, Ryousuke Satou> ;Journal of the Renin-Angiotensin-Aldosterone System. 2020 Jul 1
• 13 citations
  Bacterial TLR4 and NOD2 signaling linked to reduced mitochondrial energy function in active inflammatory bowel disease.
  Emmanuelle Ruiz, Harrison M. Penrose, Sandra Heller, Hani Nakhoul, Melody Baddoo, Erik F. Flemington, Emad Kandil, Suzana D. Savkovic> ;Gut Microbes. 2020 May 3
• 27 citations
  Loss of Forkhead Box O3 Facilitates Inflammatory Colon Cancer: Transcriptome Profiling of the Immune Landscape and Novel Targets.
  Harrison M. Penrose, Chloe Cable, Sandra Heller, Nathan Ungerleider, Hani Nakhoul, Melody Baddoo, Alifiani B. Hartono, Sean B. Lee, Matthew E. Burow, Erik F. Flemingto...> ;Cellular and Molecular Gastroenterology and Hepatology. 2019 Jan 1
• 101 citations
  Inflammation as a Regulator of the Renin-Angiotensin System and Blood Pressure
  Ryousuke Satou, Harrison M. Penrose, L. Gabriel Navar> ;Current Hypertension Reports. 2018 Oct 5
• 8 citations
  In colonic ρ0 (rho0) cells reduced mitochondrial function mediates transcriptomic alterations associated with cancer
  Harrison M. Penrose, Sandra Heller, Chloe Cable, Hani Nakhoul, Nate Ungerleider, Melody Baddoo, Zachary F. Pursell, Erik K. Flemington, Susan E. Crawford, Suzana D. Sa...> ;Oncoscience. 2017 Nov 1
• 20 citations
  Reduced mitochondrial activity in colonocytes facilitates AMPKα2-dependent inflammation.
  Sandra Heller, Harrison M. Penrose, Chloe Cable, Debjani Biswas, Hani Nakhoul, Melody Baddoo, Erik K. Flemington, Susan E. Crawford, Suzana D. Savkovic> ;FASEB Journal. 2017 Feb 9
• 28 citations
  High-fat diet induced leptin and Wnt expression: RNA-sequencing and pathway analysis of mouse colonic tissue and tumors.
  Harrison M. Penrose, Sandra Heller, Chloe Cable, Hani Nakhoul, Melody Baddoo, Erik K. Flemington, Susan E. Crawford, Suzana D. Savkovic> ;Carcinogenesis. 2017 Mar 1
• 26 citations
  VSL#3 Probiotic Stimulates T-cell Protein Tyrosine Phosphatase-mediated Recovery of IFN-γ-induced Intestinal Epithelial Barrier Defects.
  Moorthy Krishnan, Harrison M. Penrose, Nilay N. Shah, Ronald R. Marchelletta, Declan F. McCole> ;Inflammatory Bowel Diseases. 2016 Dec 1
• 22 citations
  Macrophage-derived IL-6 contributes to ANG II-mediated angiotensinogen stimulation in renal proximal tubular cells
  Ryan O'Leary, Harrison M. Penrose, Kayoko Miyata, Ryousuke Satou> ;American Journal of Physiology. Renal Physiology. 2016 Mar 23
• 18 citations
  Intestinal inflammation requires FOXO3 and prostaglandin E2-dependent lipogenesis and elevated lipid droplets.
  Sandra Heller, Chloe Cable, Harrison M. Penrose, Rania Makboul, Debjani Biswas, Maleen Cabe, Susan E. Crawford, Suzana D. Savkovic> ;American Journal of Physiology. Gastrointestinal and Liver Physiology. 2016 Mar 11
• 34 citations
  Epidermal growth factor receptor mediated proliferation depends on increased lipid droplet density regulated via a negative regulatory loop with FOXO3/Sirtuin6.
  Harrison M. Penrose, Sandra Heller, Chloe Cable, Rania Makboul, Gita Chadalawada, Ying Chen, Susan E. Crawford, Suzana D. Savkovic> ;Biochemical and Biophysical Research Communications. 2016 Jan 15
• 6 citations
  A comparison of linaclotide and lubiprostone dosing regimens on ion transport responses in human colonic mucosa
  Sang Bum Kang, Ronald R. Marchelletta, Harrison M. Penrose, Michael J. Docherty, Declan F. McCole> ;Pharmacology Research & Perspectives. 2015 Mar 1
• 23 citations
  Spermidine Stimulates T Cell Protein-tyrosine Phosphatase-mediated Protection of Intestinal Epithelial Barrier Function
  Harrison M. Penrose, Ronald R. Marchelletta, Moorthy Krishnan, Declan F. McCole> ;The Journal of Biological Chemistry. 2013 Nov 8
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