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Office
9000 Rockville Pike
Bethesda, MD 20892Phone+1 301-480-6916Fax+1 301-402-0789- Is this information wrong?
Education & Training
- University of Pennsylvania Health SystemResidency, Internal Medicine, 1972 - 1974
- Yale School of MedicineClass of 1972
Certifications & Licensure
- MD State Medical License 1986 - 2025
- PA State Medical License 1973 - 1976
- American Board of Internal Medicine Internal Medicine
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 1988
Clinical Trials
- Recruitment and Apheresis Collection of Peripheral Blood Hematopoietic Stem Cells, Mononuclear Cells and Granulocytes Start of enrollment: 1994 Feb 27
- Evaluation of Patients With Immune Function Abnormalities Start of enrollment: 2005 Sep 19
- Patients Treated for Chronic Granulomatous Disease (CGD) Since 1995 Start of enrollment: 2014 Jun 01
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Publications & Presentations
PubMed
- Allogeneic hematopoietic cell transplantation is effective for p47phox chronic granulomatous disease: A Primary Immune Deficiency Treatment Consortium study.Grunebaum, E., Arnold, D., Logan, B., Parikh, S., Marsh, R., Griffith, L., Mallhi, K., Chellapandian, D., Lim, S., Deal, C., Kapoor, N., Murguía-Favela, L., Falcone, E...> ;The Journal of Allergy and Clinical Immunology. 2024 Jan 28
- Posttransplantation late complications increase over time for patients with SCID: A Primary Immune Deficiency Treatment Consortium (PIDTC) landmark study.Eissa, H., Thakar, M., Shah, A., Logan, B., Griffith, L., Dong, H., Parrott, R., O'Reilly, R., Dara, J., Kapoor, N., Forbes Satter, L., Chandra, S., Kapadia, M., Chand...> ;The Journal of Allergy and Clinical Immunology. 2024 Jan 1
- Genetically Corrected RAG2-SCID Human Hematopoietic Stem Cells Restore V(D)J-Recombinase and Rescue Lymphoid Deficiency.Pavel-Dinu, M., Gardner, C., Nakauchi, Y., Kawai, T., Delmonte, O., Palterer, B., Bosticardo, M., Pala, F., Viel, S., Malech, H., Ghanim, H., Bode, N., Kurgan, G., Det...> ;Blood Advances. 2023 Dec 14
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Journal Articles
- A Novel Method for Screening Adenosine Receptor Specific Agonists for Use in Adenosine Drug DevelopmentHarry Malech, MD, Nature
Abstracts/Posters
- Preclinical Evaluation for Engraftment of Gene-Edited CD34+ Cells with a Sickle Cell Disease Mutation in a Rhesus Transplantation ModelHarry L. Malech, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
- Gene Editing and mRNA-Based Therapy: Two Complementary Therapeutic Approaches for the Treatment of Patients with Xmen DiseaseHarry L. Malech, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
- Enhanced Transduction Lentivector Gene Therapy for Treatment of Older Patients with X-Linked Severe Combined ImmunodeficiencyHarry L. Malech, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
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Press Mentions
- Waning Treatment for Immune Deficiency Is a Warning for All ‘One-and-Done’ TherapiesDecember 19th, 2019
- SIRION Biotech Licenses Technology to National Institute of Allergy and Infectious Diseases to Boost Clinical Efficacy of Lentivector Gene Therapy for X-linked SCIDJune 11th, 2019
- Gene Therapy Cures Babies with “Bubble Boy” DiseaseApril 19th, 2019
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Grant Support
- Gene Therapy Basic Research To Treat Inherited Primary Immune DeficienciesNational Institute Of Allergy And Infectious Diseases2009–2011
- Basic Research On Hematopoietic Human Stem CellsNational Institute Of Allergy And Infectious Diseases2009–2011
- Gene Therapy Basic Research To Treat Inherited Immune DeficienciesNational Institute Of Allergy And Infectious Diseases2007–2008
- Clinical Treatment Of Patients With Chronic Graft Versus Host DiseaseNational Institute Of Allergy And Infectious Diseases2007–2008
- Basic Research On Hematopoietic Adult Human Stem CellsNational Institute Of Allergy And Infectious Diseases2007–2008
- Gene Therapy Clinical Trials For X-Linked Severe Combined ImmunodeficiencyNational Institute Of Allergy And Infectious Diseases2007
- Clinical Diagnostic Studies And Treatment Of Patients With Immune DeficienciesNational Institute Of Allergy And Infectious Diseases2007
- Gene Therapy And Allogeneic Transplantation For Immune DNational Institute Of Allergy And Infectious Diseases2006
- Biology Of Peripheral Blood Progenitors--A Target For GENational Institute Of Allergy And Infectious Diseases2002–2006
- Biology Of Peripheral Blood ProgenitorsNational Institute Of Allergy And Infectious Diseases2005
- Gene Therapy For Immune DeficienciesNational Institute Of Allergy And Infectious Diseases1992–2005
- Peripheral Blood Progenitors--Target For Gene TransferNational Institute Of Allergy And Infectious Diseases2004
- Biology Of Peripheral Blood Progenitors In Gene TransferNational Institute Of Allergy And Infectious Diseases2003
- Peripheral Blood Progenitors--A Target For Gene TransferNational Institute Of Allergy And Infectious Diseases2001
- Biology Of Peripheral Blood Progenitors--A Target For Gene TransferNational Institute Of Allergy And Infectious Diseases1992–2000
- Peripheral Blood Progenitors-Target For Gene TransferNational Institute Of Allergy And Infectious Diseases1998
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