HenrySimpkinsMD

PubMed

• 24 citations
  The role of Nrf2 and ATF2 in resistance to platinum-based chemotherapy
  Jianli Chen, Charalambos C. Solomides, Fiona Simpkins, Henry Simpkins> ;Cancer Chemotherapy and Pharmacology. 2017 Jan 24
• 42 citations
  Cisplatin resistance in human cervical, ovarian and lung cancer cells
  Jianli Chen, Charalambos C. Solomides, Hemant K. Parekh, Fiona Simpkins, Henry Simpkins> ;Cancer Chemotherapy and Pharmacology. 2015 Apr 18
• 14 citations
  Sensitization of mesothelioma cells to platinum-based chemotherapy by GSTπ knockdown
  Jianli Chen, Charalambos C. Solomides, Henry Simpkins> ;Biochemical and Biophysical Research Communications. 2014 Apr 25
• 3 citations
  Downregulation of glutathione transferase π sensitizes lymphoma/leukaemia cells to platinum-based chemotherapy.
  Jianli Chen, Matthew Hurford, Sabeen Mekan, Henry Simpkins> ;British Journal of Haematology. 2013 Jul 1
• Is this pathological
  Jumoke Oladipo, Alex Racco, Henry Simpkins> ;Clinical Chemistry. 2013 Feb 1
• 28 citations
  Resistance to platinum-based chemotherapy in lung cancer cell lines
  Jianli Chen, Nashwa Emara, Charalambos C. Solomides, Hemant K. Parekh, Henry Simpkins> ;Cancer Chemotherapy and Pharmacology. 2010 Feb 21
• 22 citations
  The CCAAT box binding transcription factor, nuclear factor-Y (NF-Y) regulates transcription of human aldo-keto reductase 1C1 (AKR1C1) gene.
  Rajash Pallai, Henry Simpkins, Jianli Chen, Hemant K. Parekh> ;Gene. 2010 Jul 1
• 52 citations
  Dihydrodiol dehydrogenases regulate the generation of reactive oxygen species and the development of cisplatin resistance in human ovarian carcinoma cells
  Jianli Chen, Mahesha Adikari, Rajash Pallai, Hemant K. Parekh, Henry Simpkins> ;Cancer Chemotherapy and Pharmacology. 2008 May 1
• 60 citations
  Ubiquitous induction of resistance to platinum drugs in human ovarian, cervical, germ-cell and lung carcinoma tumor cells overexpressing isoforms 1 and 2 of dihydrodio...
  Hong Bing Deng, Mahesha Adikari, Hemant K. Parekh, Henry Simpkins> ;Cancer Chemotherapy and Pharmacology. 2004 May 11
• 41 citations
  Overexpression of sorcin, a calcium-binding protein, induces a low level of paclitaxel resistance in human ovarian and breast cancer cells.
  Hemant K. Parekh, Hong Bing Deng, Khuram Choudhary, Steven R. Houser, Henry Simpkins> ;Biochemical Pharmacology. 2002 Mar 15
• 75 citations
  Increased expression of dihydrodiol dehydrogenase induces resistance to cisplatin in human ovarian carcinoma cells.
  Hong B. Deng, Hemant K. Parekh, KuaChih Chow, Henry Simpkins> ;The Journal of Biological Chemistry. 2002 Apr 26
• 57 citations
  Lymphomas of the oral cavity: histology, immunologic type, and incidence of Epstein-Barr virus infection.
  Charalambos C. Solomides, Arthur S. Miller, Robert A Christman, Jotica Talwar, Henry Simpkins> ;Human Pathology. 2002 Feb 1
• 11 citations
  Cisplatin induced intermediate filament reorganization and altered mitochondrial function in 3T3 cells and drug-sensitive and -resistant Walker 256 cells.
  Robert M. Evans, Henry Simpkins> ;Experimental Cell Research. 1998 Nov 25
• 42 citations
  The transport and binding of taxol
  Hemant K. Parekh, Henry Simpkins> ;General Pharmacology. 1997 Aug 1
• 186 citations
  Arrest of spermatogenesis and defective breast development in mice lacking A-myb.
  A Toscani, R V Mettus, Coupland R, Simpkins H, Judith Litvin, Joanne M. Orth, Kimi S. Hatton, E P Reddy> ;Nature. 1997 Apr 17
• 3 citations
  Isolation of a hamster cDNA homologous to the mouse and human cyclin kinase inhibitory protein p27Kip1
  Hemant K. Parekh, Kodandaram Pillarisetti, Satya P. Kunapuli, Henry Simpkins> ;Somatic Cell and Molecular Genetics. 1997 Mar 1
• 76 citations
  Acquisition of taxol resistance via P-glycoprotein- and non-P-glycoprotein-mediated mechanisms in human ovarian carcinoma cells.
  Hemant K. Parekh, Kenneth Wiesen, Henry Simpkins> ;Biochemical Pharmacology. 1997 Feb 21
• 7 citations
  Expression of the Cisplatin Resistance Phenotype in a Human Ovarian Carcinoma Cell Line Segregates with Chromosomes 11 and 16
  Beloo Mirakhur, Hemant K. Parekh, Henry Simpkins> ;Cancer Research. 1996 May 15
• 21 citations
  Species-specific differences in taxol transport and cytotoxicity against human and rodent tumor cells : evidence for an alternate transport system ?
  Hemant K. Parekh, Henry Simpkins> ;Biochemical Pharmacology. 1996 Feb 9
• 23 citations
  Cross-resistance and collateral sensitivity to natural product drugs in cisplatin-sensitive and -resistant rat lymphoma and human ovarian carcinoma cells
  Hemant K. Parekh, Henry Simpkins> ;Cancer Chemotherapy and Pharmacology. 1996 Jan 1
• 30 citations
  The Differential Expression of Cytokeratin 18 in Cisplatin-sensitive and -resistant Human Ovarian Adenocarcinoma Cells and Its Association with Drug Sensitivity
  Hemant K. Parekh, Henry Simpkins> ;Cancer Research. 1995 Nov 15
• 12 citations
  Increase in the ATP signal after treatment with cisplatin in two different cell lines studied by 31P NMR spectroscopy.
  Kirsten Berghmans, Jesús Ruiz-Cabello, Henry Simpkins, Paul A. Andrews, Jack S. Cohen> ;Biochemical and Biophysical Research Communications. 1992 Feb 28
• 9 citations
  Pancreatic pathology in pentamidine-induced diabetes in acquired immunodeficiency syndrome patients
  Leana Hauser, Peter Sheehan, Henry Simpkins> ;Human Pathology. 1991 Sep 1
• 39 citations
  A Morphological and Phenotypic Analysis of Walker 256 Cells
  Henry Simpkins, John M. Lehman, Joseph E. Mazurkiewicz, Bruce H. Davis> ;Cancer Research. 1991 Feb 15
• Acute granular lymphoid leukemia.
  Ricardo E. Duque, Henry Simpkins> ;Human Pathology. 1987 Aug 1
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