HerbertLyerlyMDFACS

PubMed

• Vaccines targetingactivating mutations elicit anti-tumor immune responses and suppress estrogen signaling in therapy resistant ER+ breast cancer.
  Dailey, G., Rabiola, C., Lei, G., Wei, J., Yang, X., Wang, T., Liu, C., Gajda, M., Hobeika, A., Summers, A., Marek, R., Morse, M., Crosby, E., Hartman, Z., Lyerly, H.> ;Human Vaccines & Immunotherapeutics. 2024 Dec 31
• Overcoming Xenoantigen Immunity to Enable Cellular Tracking and Gene Regulation with Immune-competent "NoGlow" Mice.
  Timothy N Trotter, Andrea Wilson, Jason McBane, Carina E Dagotto, Xiao-Yi Yang, Jun-Ping Wei, Gangjun Lei, Hannah Thrash, Joshua C Snyder, Zachary C Hartman, Herbert K...> ;Cancer Research Communications. 2024 Apr 9
• CEA vaccines.
  Bhagat, A., Morse, M., Hartman, Z., Lyerly, H.> ;Human Vaccines & Immunotherapeutics. 2023 Dec 15
• 3 citations
  Dormant tumors circumvent tumor-specific adaptive immunity by establishing a Treg-dominated niche via DKK3.
  Timothy N Trotter, Carina E Dagotto, Delila Serra, Tao Wang, Xiao Yang, Chaitanya R Acharya, Junping Wei, Gangjun Lei, H Kim Lyerly, Zachary C Hartman> ;JCI Insight. 2023 Nov 22
• 1 citations
  Beyond Neoantigens: Antigens Derived from Tumor Drivers as Cancer Vaccine Targets.
  Erika J Crosby, Zachary C Hartman, H Kim Lyerly> ;Clinical Cancer Research. 2023 Sep 1
• 2 citations
  Self-replicating messenger RNA based cancer immunotherapy.
  Herbert Kim Lyerly> ;Cancer Gene Therapy. 2023 Jun 1
• 15 citations
  Clinical trials of self-replicating RNA-based cancer vaccines.
  Michael A Morse, Erika J Crosby, Jeremy Force, Takuya Osada, Amy C Hobeika, Zachary C Hartman, Peter Berglund, Jonathan Smith, H Kim Lyerly> ;Cancer Gene Therapy. 2023 Jun 1
• A Non-Invasive Deep Photoablation Technique to Inhibit DCIS Progression and Induce Antitumor Immunity.
  Kensuke Kaneko, Hiroshi Nagata, Xiao-Yi Yang, Joshua Ginzel, Zachary Hartman, Jeffrey Everitt, Philip Hughes, Timothy Haystead, Michael Morse, Herbert Kim Lyerly, Taku...> ;Cancers. 2022 Nov 23
• 9 citations
  Combination of a novel heat shock protein 90-targeted photodynamic therapy with PD-1/PD-L1 blockade induces potent systemic antitumor efficacy and abscopal effect agai...
  Kensuke Kaneko, Chaitanya R Acharya, Hiroshi Nagata, Xiao Yang, Zachary Conrad Hartman, Amy Hobeika, Philip F Hughes, Timothy A J Haystead, Michael A Morse, Herbert Ki...> ;Journal for Immunotherapy of Cancer. 2022 Sep 1
• 3 citations
  Epidemiology of geographic disparities in heart failure among US older adults: a Medicare-based analysis.
  Bin Yu, Igor Akushevich, Arseniy P Yashkin, Anatoliy I Yashin, H Kim Lyerly, Julia Kravchenko> ;BMC Public Health. 2022 Jul 1
• 10 citations
  Gene expression signatures of individual ductal carcinoma in situ lesions identify processes and biomarkers associated with progression towards invasive ductal carcinoma.
  Clare A Rebbeck, Jian Xian, Susanne Bornelöv, Joseph Geradts, Amy Hobeika, Heather Geiger, Jose Franco Alvarez, Elena Rozhkova, Ashley Nicholls, Nicolas Robine, Herber...> ;Nature Communications. 2022 Jun 13
• 3 citations
  Action for Increasing Diversity, Market Access, and Capacity in Oncology Registration Trials-Is Africa the Answer? Report From a Satellite Session of the Accelerating ...
  Darya Kizub, Cathyryne K Manner, Katy Graef, Bello Abubakar, Jackson Orem, Folakemi Odedina, Mojisola Christianah Adeyeye, Gertrude Nakigudde, Kassa Ayalew, Chitkala K...> ;JCO Global Oncology. 2022 Jun 1
• 12 citations
  Trastuzumab/pertuzumab combination therapy stimulates antitumor responses through complement-dependent cytotoxicity and phagocytosis.
  Li-Chung Tsao, Erika J Crosby, Timothy N Trotter, Junping Wei, Tao Wang, Xiao Yang, Amanda N Summers, Gangjun Lei, Christopher A Rabiola, Lewis A Chodosh, William J Mu...> ;JCI Insight. 2022 Mar 22
• 4 citations
  Sensitizing immune unresponsive colorectal cancers to immune checkpoint inhibitors through MAVS overexpression.
  Bin-Jin Hwang, Li-Chung Tsao, Chaitanya R Acharya, Timothy Trotter, Pankaj Agarwal, Junping Wei, Tao Wang, Xiao-Yi Yang, Gangjun Lei, Takuya Osada, Herbert Kim Lyerly,...> ;Journal for Immunotherapy of Cancer. 2022 Mar 1
• 27 citations
  Combination of ultrasound-based mechanical disruption of tumor with immune checkpoint blockade modifies tumor microenvironment and augments systemic antitumor immunity.
  Shinya Abe, Hiroshi Nagata, Erika J Crosby, Yoshiyuki Inoue, Kensuke Kaneko, Cong-Xiao Liu, Xiao Yang, Tao Wang, Chaitanya R Acharya, Pankaj Agarwal, Joshua Snyder, Wi...> ;Journal for Immunotherapy of Cancer. 2022 Jan 1
• 3 citations
  HSP90-Specific nIR Probe Identifies Aggressive Prostate Cancers: Translation from Preclinical Models to a Human Phase I Study.
  Takuya Osada, Erika J. Crosby, Kensuke Kaneko, Joshua C. Snyder, Joshua D. Ginzel, Chaitanya R. Acharya, Xiao Yi Yang, Thomas J. Polascik, Ivan Spasojevic, Rendon C. N...> ;Molecular Cancer Therapeutics. 2021 Oct 21
• 12 citations
  Blood microbiota diversity determines response of advanced colorectal cancer to chemotherapy combined with adoptive T cell immunotherapy.
  Duo Yang, Xiaoli Wang, Xinna Zhou, Jing Zhao, Huabing Yang, Shuo Wang, Michael A. Morse, Jiangping Wu, Yanhua Yuan, Sha Li, Amy Hobeika, Herbert Kim Lyerly, Jun Ren> ;Oncoimmunology. 2021 Sep 27
• 2 citations
  A Grant-Based Experiment to Train Clinical Investigators: The AACR/ASCO Methods in Clinical Cancer Research Workshop.
  Daniel D. Von Hoff, Gary M. Clark, Charles A. Coltman, Mary L. Disis, S.G. Eckhardt, Lee M. Ellis, Margaret Foti, Elizabeth Garrett-Mayer, Mithat Gonen, Manuel Hidalgo...> ;Clinical Cancer Research. 2021 Jul 26
• 29 citations
  Exposure to low-dose ambient fine particulate matter PM2.5 and Alzheimer's disease, non-Alzheimer's dementia, and Parkinson's disease in North Carolina.
  Sung Han Rhew, Julia Kravchenko, H. Kim Lyerly> ;Plos One. 2021 Jul 9
• 4 citations
  HER2 Isoforms Uniquely Program Intratumor Heterogeneity and Predetermine Breast Cancer Trajectories During the Occult Tumorigenic Phase
  Joshua D. Ginzel, Chaitanya R. Acharya, Veronica Lubkov, Hidetoshi Mori, Peter G. Boone, Lauren K. Rochelle, Wendy Roberts, Jeffrey I. Everitt, Zachary C. Hartman, Eri...> ;Molecular Cancer Research. 2021 Jun 15
• 3 citations
  Changes in Peripheral Blood Regulatory T Cells and IL-6 and IL-10 Levels Predict Response of Pediatric Medulloblastoma and Germ Cell Tumors With Residual or Disseminat...
  Linan Song, Shuo Wang, Tong Fang, Xiaoguang Qiu, Xiaoli Wang, Xinna Zhou, Michael A. Morse, Amy Hobeika, Wanshui Wu, Huabing Yang, Jun Ren, Herbert Kim Lyerly> ;International Journal of Radiation Oncology, Biology, Physics. 2021 May 8
• 27 citations
  Intratumoral Plasmid IL12 Expands CD8+ T Cells and Induces a CXCR3 Gene Signature in Triple-negative Breast Tumors that Sensitizes Patients to Anti-PD-1 Therapy.
  Melinda L. Telli, Hiroshi Nagata, Irene Wapnir, Chaitanya R. Acharya, Kaitlin Zablotsky, Bernard A. Fox, Carlo Bifulco, Shawn M. Jensen, Carmen Ballesteros-Merino, Mai...> ;Clinical Cancer Research. 2021 May 1
• Targeting the glucagon receptor signaling pathway as a novel strategy to counteract PI3K inhibitor induced hyperglycemia while sustaining tumor PI3K inhibition.
  Jie Wang, Takuya Osada, Michael A. Morse, Frank Calzone, Hai Yan, Dung Thai, H. Kim Lyerly> ;Leukemia & Lymphoma. 2021 Feb 12
• 3 citations
  Cancer vaccines: the importance of targeting oncogenic drivers and the utility of combinations with immune checkpoint inhibitors
  Erika J. Crosby, H. Kim Lyerly, Zachary C. Hartman> ;Oncotarget. 2021 Jan 5
• 2 citations
  Serial assessment of circulating T lymphocyte phenotype and receptor repertoire during treatment of non-muscle invasive bladder cancer with adoptive T cell immunotherapy.
  Xiaoli Wang, Guoliang Qiao, Ni Jiang, Michael A. Morse, Xinna Zhou, Shuo Wang, Jiangping Wu, Yuguang Song, Yanjie Zhao, Lei Zhou, Yanhua Yuan, Amy Hobeika, Jun Ren, He...> ;American Journal of Cancer Research. 2021 Apr 15
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Journal Articles

• Improved Tumor Targeting of Anti-HER2 Nanobody Through N-Succinimidyl 4-Guanidinomethyl-3-Iodobenzoate Radiolabeling  
  Pruszynski M, Koumarianou E, Vaidyanathan G, Revets H, Devoogdt N, Lahoutte T, Lyerly HK, Zalutsky MR, J Nucl Med, 4/1/2014
• Modulation of Immune System Inhibitory Checkpoints in Colorectal Cancer  
  Sandip P. Patel, Takuya Osada, Koya Osada, Herbert Hurwitz, H. Kim Lyerly & Michael A. Morse, Curr Colorectal Cancer Rep, 8/13/2013
• A Randomized Phase II Study of Immunization With Dendritic Cells Modified With Poxvectors Encoding CEA and MUC1 Compared With the Same Poxvectors Plus GM-CSF for Resec...  
  Morse MA, Niedzwiecki D, Marshall JL, Garrett C, Chang DZ, Aklilu M, Crocenzi TS, Cole DJ, Dessureault S, Hobeika AC, Osada T, Onaitis M, Clary BM, Hsu D, Devi GR, Bul..., Ann Surg, 5/1/2013
• Elevated level of peripheral CD8+CD28 - T lymphocytes are an independent predictor of progression-free survival in patients with metastatic breast cancer during the co...  
  Song G, Wang X, Jia J, Yuan Y, Wan F, Zhou X, Yang H, Ren J, Gu J, Lyerly HK, Cancer Immunol Immunother, 4/21/2013
• Constitutive Internalization of the Leucine-rich G protein-coupled Receptor-5 (LGR5) to the trans-Golgi Network  
  Snyder JC, Rochelle LK, Lyerly HK, Caron MG, Barak LS, J Biol Chem, 4/1/2013
• Specific Genetic polymorphisms of IL10-592 AA and IL10-819 TT genotype lead key role for inducing docetaxel-induced liver injury in breast cancer patients  
  Cao B, Jia J, Ma L, Di L, Song G, Yuan Y, Ma B, Zhu Y, Yu J, Wang X, Zhou X, Lyerly HK, Ren J, Clin Transl Oncol, 11/1/2012
• Identification of a novel Smoothened antagonist that potently suppresses Hedgehog signaling  
  Wang J, Mook RA Jr, Lu J, Gooden DM, Ribeiro A, Guo A, Barak LS, Lyerly HK, Chen W, Bioorg Med Chem, 11/1/2012
• Recombinant human endostatin could eliminate the pro-angiogenesis priority of SP cells sorted from non-small cell lung cancer cells  
  Cao B, Jia J, Ma L, Di L, Song G, Yuan Y, Ma B, Zhu Y, Yu J, Wang X, Zhou X, Lyerly HK, Ren J, Clin Transl Oncol, 8/1/2012
• Novel recombinant alphaviral and adenoviral vectors for cancer immunotherapy  
  Osada T, Morse MA, Hobeika A, Lyerly HK, Semin Oncol, 6/1/2012
• Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer  
  Cheng Q, Chang JT, Geradts J, Neckers LM, Haystead T, Spector N, Lyerly HK, Breast Cancer Res, 4/1/2012
• Phase I clinical trial of HER2-specific immunotherapy with concomitant HER2 kinase inhibtion  
  Hamilton E, Blackwell K, Hobeika AC, Clay TM, Broadwater G, Ren XR, Chen W, Castro H, Lehmann F, Spector N, Wei J, Osada T, Lyerly HK, Morse MA, J Transl Med, 2/1/2012
• MHC class I-presented lung cancer-associated tumor antigens identified by immunoproteomics analysis are targets for cancer-specific T cell response  
  Shetty V, Sinnathamby G, Nickens Z, Shah P, Hafner J, Mariello L, Kamal S, Vlahovic' G, Lyerly HK, Morse MA, Philip R, J Proteomics, 5/1/2011
• HER2 overexpression elicits a pro-inflammatory IL-6 autocrine signaling loop that is critical for tumorigenesis  
  Zachary C. Hartman, Xiao-Yi Yang, Oliver Glass, Gangjun Lei, Takuya Osada, Sandeep Dave, Michael Morse, Timothy M. Clay, H. Kim Lyerly, Cancer Res, 4/25/2011
• Polyclonal immune responses to antigens associated with cancer signaling pathways and new strategies to enhance cancer vaccines  
  Clay TM, Osada T, Hartman ZC, Hobeika A, Devi G, Morse MA, Kim Lyerly H, Immunol Res, 4/1/2011
• CSPG4 as a new target for antibody – based immunotherapy of triple negative breast cancer  
  Wang X, Osada T, Wang Y, Yu L, Sakakura K, Katayama A, McCarthy JB, Brufsky A, Chivukula M, Khoury T, Hsu DS, Barry WT, Lyerly HK, Clay TM, Ferrone S, J Natl Cancer Inst, 10/1/2010
• Immune signatures predict prognosis in localized cancer  
  Hsu DS, Kim MK, Balakumaran BS, Acharya CR, Anders CK, Clay T, Lyerly HK, Drake CG, Morse MA, Febbo PG, Cancer Invest, 8/1/2010
• Identification of select glucocorticoids as Smoothened agonists: Potential utility for regenerative medicine  
  Wang J, Lu J, Bond MC, Chen M, Ren XR, Lyerly HK, Barak LS, Chen W, Proc Natl Acad Sci U S A, 5/3/2010
• Anti-tumor immunotherapy despite immunity to adenovirus using a novel adenoviral vector Ad5 [E1-, E2b-]-CEA  
  Gabitzsch ES, Xu Y, Balint JP Jr, Hartman ZC, Lyerly HK, Jones FR, Cancer Immunol Immunother, 4/2/2010
• An adenoviral vaccine encoding full-length inactivated human HER2 exhibits potent immunogenicity and enhanced therapeutic efficacy without oncogenicity  
  Hartman Z, Osada T, Hobeika AC, Morse MA, Amalfitano A, Lyerly HK, Clay TM, Clin Cancer Res, 3/1/2010
• The Anti-Helminthic Niclosamide Inhibits Wnt/Frizzled1 Signaling  
  Chen M, Wang J, Lu J, Bond MC, Ren XR, Lyerly HK, Barak LS, Chen W, Biochemistry, 9/22/2009
• Use of tablet personal computers for sensitive patient-reported information  
  Dupont A, Wheeler J, Herndon JE 2nd, Coan A, Zafar SY, Hood L, Patwardhan M, Shaw HS, Lyerly HK, Abernethy AP, J Support Oncol, 5/1/2009
• Induction of Wilms' tumor protein (WT1)-specific antitumor immunity using a truncated WT1-expressing adenovirus vaccine  
  Osada T, Woo CY, McKinney M, Yang XY, Lei G, Labreche HG, Hartman ZC, Niedzwiecki D, Chao N, Amalfitano A, Morse MA, Lyerly HK, Clay TM, Clin Cancer Res, 4/1/2009
• The effect of anti-VEGF therapy on immature myeloid cell and dendritic cells in cancer patients  
  Osada T, Chong G, Tansik R, Hong T, Spector N, Kumar R, Hurwitz HI, Dev I, Nixon AB, Lyerly HK, Clay T, Morse MA, Cancer Immunol Immunother, 8/1/2008
• Depletion of human regulatory T cells specifically enhances antigen-specific immune responses to cancer vaccines  
  Morse MA, Hobeika AC, Osada T, Serra D, Niedzwiecki D, Lyerly HK, Clay TM, Blood, 8/1/2008
• Current immunotherapeutic strategies in colon cancer  
  Morse M, Langer L, Starodub A, Hobeika A, Clay T, Lyerly HK, Surg Oncol Clin N Am, 10/1/2007
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Books/Book Chapters

• Primary and Secondary Liver Tumors: Current and Emerging Therapies 
  Lyerly HKEditors: Clavien PA, Fong Y, Lyerly HK, Morse MM, Venook A, Crawford J.Blackwell Science, Inc., Malden, MAEdition 2nd,2004
• Cancer Vaccines 
  Lyerly HKEditors: Morse MM, Lyerly HK, Clay TA.Human Press2004
• Pocket Surgery 
  Lyerly HKEditors: Mosca PJ, Clark LA, Pappas TN, Lyerly HK.Wilkins Publishers2002
• Surgical Oncology: Contemporary Principles and Practice 
  Chapter: Overview of Clinical Oncology, Gene Therapy of Cancer 
  Morse MM, Clary BM, Lyerly HKEditors: Bland KI, Daly JM, and Karakousis CP.McGraw-Hill, New York2001
• Surgical Research 
  Lyerly HKEditors: Souba WW and Willmore DW.Academic Press, San Diego2001
• Primary and Secondary Liver Tumors: Current and Emerging Therapies 
  Chapter: Overview: Molecular, Genetic, Immunology and Neovascularization of Liver Tumors 
  Morse MM, Lyerly HKEditors: Clavien PA, Fong Y, Lyerly HK, Morse MM, Venook A, Crawford J.Blackwell Science, Inc., Malden, MA1999
• Primary and Secondary Liver Tumors: Current and Emerging Therapies 
  Chapter: Prodrug Converting Enzyme Therapy For Hepatic Tumors 
  Clary BM, Lyerly HKEditors: Clavien PA, Fong Y, Lyerly HK, Morse MM, Venook A, Crawford J.Blackwell Science, Inc., Malden, MA1999
• Primary and Secondary Liver Tumors: Current and Emerging Therapies 
  Lyerly HKEditors: Clavien PA, Fong Y, Lyerly HK, Morse MM, Venook A, Crawford J.Blackwell Science, Inc., Malden, MA1999
• Textbook of Surgery: The Biological Basis of Modern Surgical Practice 
  Chapter: Molecular Biology in Surgery 
  Lyerly, HK, Sullenger BAEditors: Sabiston DC Jr.W.B. Saunders Co, PhiladelphiaEdition 15th,1997
• Textbook of Surgery: The Biological Basis of Modern Surgical Practice 
  Chapter: Immunology and Immunotherapy of Neoplastic Disease 
  Lyerly HK, Gelber CEditors: Sabiston DC Jr.W.B. Saunders Co, PhiladelphiaEdition 15th,1997
• Textbook of Surgery: The Biological Basis of Modern Surgical Practice 
  Chapter: Meckel's Diverticulum 
  Clary BM, Lyerly HKEditors: Sabiston DC Jr.W.B. Saunders Co, PhiladelphiaEdition 15th,1997
• Textbook of Surgery: The Biological Basis of Modern Surgical Practice 
  Chapter: Carcinoma of the Colon and Rectum 
  Lyerly HKEditors: Sabiston DC Jr.W.B. Saunders Co, PhiladelphiaEdition 15th,1997
• Textbook of Surgery Pocket Companion 
  Chapter: Molecular Biology in Surgery 
  Lyerly, HK, Sullenger BAEditors: Sabiston DC Jr and Lyerly HK.W.B. Saunders Co, Philadelphia1997
• Textbook of Surgery Pocket Companion 
  Chapter: Immunology and Immunotherapy of Neoplastic Disease 
  Lyerly HK, Gelber CEditors: Sabiston DC Jr and Lyerly HK.W.B. Saunders Co, Philadelphia1997
• Textbook of Surgery Pocket Companion 
  Chapter: The Thyroid Gland: Thyroiditis 
  Lyerly HKEditors: Sabiston DC Jr and Lyerly HK.W.B. Saunders Co, Philadelphia1997
• Textbook of Surgery Pocket Companion 
  Chapter: Meckel's Diverticulum 
  Clary BM, Lyerly HKEditors: Sabiston DC Jr and Lyerly HK.W.B. Saunders Co, Philadelphia1997
• Textbook of Surgery Pocket Companion 
  Chapter: Carcinoma of the Colon and Rectum 
  Lyerly HKEditors: Sabiston DC Jr and Lyerly HK.W.B. Saunders Co, Philadelphia1997
• Textbook of Surgery Pocket Companion 
  Lyerly HKEditors: Sabiston DC Jr and Lyerly HK.W.B. Saunders Co, Philadelphia1997
• Current Practice of Surgery 
  Chapter: Oncogenes in the Clinical Practice of Surgery 
  Clary BM, Winer E, Lyerly HKEditors: Warshaw A.Churchill Livingstone1995
• Essentials of Surgery 
  Chapter: Surgical Aspects of the Acquired Immunodeficiency Syndrome 
  DiMaio JM, Lyerly HKEditors: Sabiston DC Jr and Lyerly HK.W.B. Saunders Co, PhiladelphiaEdition 2nd,1994
• Essentials of Surgery 
  Chapter: Principles of Surgical Oncology 
  Lyerly HKEditors: Sabiston DC Jr and Lyerly HK.W.B. Saunders Co, PhiladelphiaEdition 2nd,1994
• Essentials of Surgery 
  Chapter: Tumor Markers 
  Lyerly HKEditors: Sabiston DC Jr and Lyerly HK.W.B. Saunders Co, PhiladelphiaEdition 2nd,1994
• Essentials of Surgery 
  Chapter: The Breast 
  Lyerly HKEditors: Sabiston DC Jr and Lyerly HK.W.B. Saunders Co, PhiladelphiaEdition 2nd,1994
• Essentials of Surgery 
  Chapter: The Colon and Rectum 
  Lyerly HK, Clary BMEditors: Sabiston DC Jr and Lyerly HK.W.B. Saunders Co, PhiladelphiaEdition 2nd,1994
• Biologic Therapy of Cancer Updates 
  Chapter: Specific Active Immunotherapy With Cytokine Gene Modified Tumor 
  Gilboa, E, Lyerly, HKJ.B. Lippincott Company, Philadelphia1994
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Abstracts/Posters

• Increased disease-free survival following adoptive transfer of tumor-specific T lymphocytes to mice with breast cancer
  Coveney E, Clary BM, Philip R, Lyerly HK, 82nd Clinical Congress of the American College of Surgeons, 10/1/1996
• Active immunotherapy of pancreatic cancer with IFN and IL2 secreting tumor cell vaccinations
  Clary BM, Coveney EC, Blazer DG III, Philip R, Gilboa E, Lyerly HK, The North Carolina Chapter of the American College of Surgeons, Resident’s Forum, 7/1/1996
• Generation of IL-2 gene transduced breast cancer cells for use in active specific immunotherapy
  Clary BM, Philip R, Coveney EC, Philip M, Gilboa E, and Lyerly HK, 18th Annual Breast Cancer Symposium, 12/1/1995
• Interleukin-7 enhances the generation of human cytotoxic T lymphocytes against Epstein-Barr Virus Transformed Cell Lines; Implications for Adoptive Immunotherapy
  Coveney E, Clary B, Iacobucci M, Philip R, Gilboa E., Lyerly HK, 81st Clinical Congress of the American College of Surgeons, 10/25/1995
• Gene Modification of Primary Tumor Cells for Active Immunotherapy of Human Breast and Ovarian Cancer
  Philip R, Clary B, Brunette E, Kilinski L, Murugesh D, Sorich M, Lebkowski J, Lyerly HK, Philip M, Biological Therapy of Cancer, 4/1/1995
• High level cytokine expression in irradiated primary human melanoma tumor cells following adeno-associated virus plasmid: cationic liposome-mediated gene transfer
  Clary BM, Coveney EC, Philip R, Blazer DG III, Seigler H, Gilboa E, Lyerly HK, The Society of University Surgeons, 37th Annual Surgical Residents’ Conference, 2/1/1995
• Inhibition of established pancreatic cancers following vaccination with interleukin-2 gene transduced tumor cells
  Clary BM, Coveney EC, Philip R, Blazer DG III, Morse M, Gilboa E, Lyerly HK, Association for Academic Surgery Annual Meeting, 1/1/1995
• CD83 is a marker for mature dendritic cells (DC) generated from peripheral blood mononuclear cells (PBMC)
  Morse, MA, LJ Zhou, TF Tedder, HK Lyerly, and C Smith, Blood, 1/1/1995
• Anti-Melanoma Cytotoxic T Lymphocytes Maintain Their Function and Phenotype Following Transformation With Herpesvirus Saimiri
  DiMaio JM, Clary BM, Coveney EC, Darrow T, Seigler H, Lyerly HK, Association for Academic Surgery, 11/1/1994
• Inhibition of Breast Cancer Metastasis by Cytokine Gene-Modified Tumor Vaccination in Tumor-Bearing Mice
  Coveney EC, Clary BM, DiMaio JM, Vieweg J, Gilboa E, Lyerly HK, American College of Surgeons 80th Annual Clinical Congress, 10/1/1994
• Gene Modification of Primary Tumor and Effector T Cells Using Adeno-Associated Viral Plasmid DNA: Liposome Complexes for Human Cancer Gene Therapy
  Philip R, Philip M, Kilinski L, Brunette E, Murugesh D, Clary B, Lyerly HK, Lebkowski J, Cold Spring Harbor Laboratory Meeting on Gene Therapy, 9/21/1994
• Directed enzyme pro-drug gene therapy for pancreatic cancer in vivo
  DiMaio JM, Via DF, Berend KR, Jordan PB, Isenberg AV, Clary BM, Lyerly HK, The Society of University Surgeons, 55th Annual Meeting, 2/1/1994
• Human B-cell lymphoma in SCID mice following active infection with EBV
  Boyle TJ, Tamburini M, Berend K, Kizilbash AM, Lyerly, HK, 53d Annual Meeting of the Society of University Surgeons, 1/1/1992
• Interleukin-6 levels are elevated in SCID mice developing human B-cell lymphoma
  Boyle TJ, Coles RE, Kizilbash AM, Lyerly HK, Annual Meeting of the Society of Surgical Oncology, 1/1/1992
• Biologic Containment of HIV-1: a Tat and Rev deficient virus
  Chen H, Malim MH, Boyle TJ, Berend KR, Cullen BR, Lyerly HK, Keystone Symposium: Prevention and Treatment of AIDS, 1/1/1992
• Transdominant Rev protein inhibits HIV replication without affecting T-cell function
  Malim MH, Freimuth WW, Liu J, Boyle TJ, Lyerly HK, Cullen BR, Nabel GJ, Annual Meeting of the American Federation for Clinical Research, 1/1/1992
• Interleukin-6 expression is not regulated by HIV-1 protein Tat
  Chen H, Boyle TJ, Lyerly HK, Proceedings of the 8th International Conference on AIDS, 1/1/1992
• ACTG augmentation of non-MHC restricted cellular cytotoxicities in patients receiving Zidovudine plus Interleukin-2
  Weinhold KJ, Tyler DS, Austin AA, Lyerly HK, Bolognesi DP, Bartlett JA, Proceedings of the 5th International Conference on AIDS, 1/1/1989
• HIV specific killer cells armed in situ with cytophilic antibodies
  Tyler DS, Nastala CL, Lyerly HK, Stanley SD, Matthews TJ, Bolognesi DP, Weinhold KJ, Fourth International Conference on AIDS, 6/12/1988
• Ontogeny and specificity of ADCC following HIV-1 infection
  Lyerly HK, Redfield R, Arthur L, Matthews TJ, Blattner W, Tyler DS, Bolognesi DP, Weinhold KJ, Fourth International Conference on AIDS, 6/12/1988
• Analysis of the immune response in a laboratory worker infected with the HTLV-IIIB strain of HIV
  Matthews TJ, Langlois AJ, Weinhold KJ, Skinner MA, Lyerly HK, Blattner WA, Bolognesi DP, Fourth International Conference on AIDS, 6/12/1988
• Cytophilic anti-HIV antibodies: The role of anti-GP120 arming antibodies in therapeutic and vaccine strategies
  Tyler DS, Nastala CL, Lyerly HK, Matthews TJ, Bolognesi DP, Weinhold KJ, Modern Approaches to New Vaccines, 1/1/1988
• Combined Zidovudine plus Interleukin-2 therapy of asymptomatic HIV-1 seropositive patients. development of cytokines for the treatment of AIDS
  Weinhold KJ, Bartlett JA, Lyerly HK, Tyler DS, Depamphilis J, Lehrman S, Bolognesi DP, Joint Meeting of the National Institute of Allergy and Infectious Diseases, National Cancer Institute and National Institute of Environmental Health Sciences, 1/1/1988
• Non-MHC restricted cellular anti-HIV cytotoxicity: a manifestation of direct ADCC: retroviruses of human AIDS and related diseases
  Weinhold KJ, Tyler DS, Lyerly HK, Foundation Macel Merieux, 1/1/1988
• Type specific binding of surface expressed GP120 by anti-GP120 serum
  Lyerly HK, Weinhold KJ, Matthews TJ, Putney S, Rusche J, Langlois AJ, Bolognesi DP, J Cellular Biochem, 1/1/1987
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