Herbert Markley, MD

Herbert Markley, MD, FAAN, FAHS

Neurology Worcester, MA

President and Director, New England Regional Headache Center, Inc.

Office Address

  • 85 Prescott St
    Worcester, MA 01605
    Phone: (508) 890-5633

Herbert Markley, MD, FAAN, FAHS

Neurology Worcester, MA

President and Director, New England Regional Headache Center, Inc.

Clinical Specialties & Interests

  • Neurology: Headache

Education & Training

  • Johns Hopkins Bayview Medical CenterJohns Hopkins Bayview Medical Center
  • University of Maryland School of MedicineUniversity of Maryland School of Medicine
  • The Johns Hopkins UniversityThe Johns Hopkins University

Certifications & Licensure

  • MA State Medical LicenseMA State Medical License1983 - 2017
  • American Board of Psychiatry and NeurologyNeurology

    Awards, Honors, & Recognition

    • Regional Top DoctorCastle Connolly, 2014
    • Best Doctors in AmericaWoodward & White, 1999, 2000, 2006
    • Migraine Pioneer AwardGlaxo Pharmaceutical, 1990

    Clinical Trials

    Publications & Presentations


    Journal Articles

    • Cluster Headache: Myths and the Evidence  Markley, HG, Buse DC, Curr Pain Headache Rep, 1/1/2006
    • A randomized trial of divalproex sodium extended-release tablets in migraine prophylaxis.  Freitag FG, Collins SD, Carlson HA, Goldstein J, Saper J, Silberstein S, Mathew N, Winner PK, Deaton R, Sommerville K; Depakote ER Migraine Study Group., Neurology, 6/1/2002
    • Multiple-attack efficacy and tolerability of sumatriptan nasal spray in the treatment of migraine.  Diamond S, Elkind A, Jackson RT, Ryan R, DeBussey S, Asgharnejad M, Arch Fam Med, 5/1/1998

    Books/Book Chapters

    • Comprehensive Review of Headache Medicine Chapter: Classification and Diagnosis of Chronic Daily Headache and Tension-Type Headache 
      Levin, M, Markley, HG
      Editors: .Oxford University Press, NY
    • Office Practice of Neurology Chapter: High- and Low-Pressure Headache 
      Samuels MA, Feske S, Markley, HG
      Editors: .Churchill Livingstone, NY


    • Naratriptan is effective for the treatment of migraine headache in sumatriptan non-responders. Stark S, S O'Quinn, S McNeal , G Putnam, C Watson, Headache, 5/1/1999
    • Efficacy and tolerability of sumatriptan nasal spray: a review of Unites States' studies. Diamond S, DeBussey S, Asghanejad M, Headache, 5/1/1997
    • Efficacy and tolerability of naratriptan tablets in the treatment of migraine: results of a double-blind, placebo-controlled, parallel-group trial. Elkind A, Webster C, Laurenza A, Austin R, Asghanejad M., Headache, 5/1/1997


    • "A Spotlight on New and Emerging Headache Treatments". The Fifth Annual HCNE Boston Headache Symposium, Headache Cooperative of New England, Boston, MA - 11/12/2005
    • Acute Treatments for Migraine The 15th Annual Headache Symposium: Headache Update 2005: Headache Cooperative of New England. Stowe - 3/4/2005
    • All Headaches Are Not Migraine The Fourth Annual HCNE Boston Headache Symposium, A Practical Approaches to Headache Diagnosis and T - 11/6/2004


    • Trigeminal Autonomic Cephalalgias Markley, HG, HCNE Newsletter

    Professional Memberships

    Hospital Affiliations

    Insurance Accepted

    • Aetna Choice POS II
    • Aetna HMO
    • BCBS Blue Card PPO
    • BCBS Massachusetts Blue Care Elect PPO
    • CIGNA Open Access
    • First Health PPO
    • Great West PPO
    • Harvard Pilgrim HMO
    • Multiplan PHCS PPO
    • Multiplan PPO
    • Tufts Health Plan PPO
    • UniCare PPO
    • United Healthcare - Direct Choice Plus POS
    • United Healthcare - Direct Options PPO
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