HidekiGarrenMD

PubMed

• Ocrelizumab efficacy in subgroups of patients with relapsing multiple sclerosis.
  Turner, B.,Cree, BAC.,Kappos, L.,Montalban, X.,Papeix, C.,Wolinsky, J. S.,Buffels, R.,Fiore, D.,Garren, H.,Han, J.,Hauser, S. L.> ;J. Neurol.. 2019 Mar 02
• Advanced imaging findings in progressive solitary sclerosis: a single lesion or a global disease?
  Lisa Eunyoung Lee, Jillian K Chan, Emilie Nevill, Adam Soares, Irene M. Vavasour, Erin L. MacMillan, Hideki Garren, David Clayton, B. Mark Keegan, Roger Tam, Anthony T...> ;Multiple sclerosis journal - experimental, translational and clinical. 2019 Jan 16
• Quantitative neuroimaging measures of myelin in the healthy brain and in multiple sclerosis.
  O'Muircheartaigh, J.,Vavasour, I.,Ljungberg, E.,Li, DKB.,Rauscher, A.,Levesque, V.,Garren, H.,Clayton, D.,Tam, R.,Traboulsee, A.,Kolind, S.> ;Hum Brain Mapp. 2019 Jan 17
• Ocrelizumab versus Placebo in Primary Progressive Multiple Sclerosis
  Xavier Montalban, Stephen L. Hauser, Ludwig Kappos, Douglas L. Arnold, Amit Bar-Or, Giancarlo Comi, Jérôme De Seze, Gavin Giovannoni, Hans-Peter Hartung, Bernhard Hemm...> ;The New England Journal of Medicine. 2017 Jan 19
• Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis.
  Hauser, S. L.,Bar-Or, A.,Comi, G.,Giovannoni, G.,Hartung, H. P.,Hemmer, B.,Lublin, F.,Montalban, X.,Rammohan, K. W.,Selmaj, K.,Traboulsee, A.,Wolinsky, J. S.,Arnold, D...> ;N. Engl. J. Med.. 2016 Dec 22
• Activity of secukinumab, an anti-IL-17A antibody, on brain lesions in RRMS: results from a randomized, proof-of-concept study.
  Havrdová E, Belova A, Goloborodko A, Tisserant A, Wright A, Wallstroem E, Garren H, Maguire RP, Johns DR> ;J. Neurol.. 2016-07-01
• Plasmid-encoded proinsulin preserves C-peptide while specifically reducing proinsulin-specific CD8⁺ T cells in type 1 diabetes.
  Roep BO, Solvason N, Gottlieb PA, Abreu JRF, Harrison LC, Eisenbarth GS, Yu L, Leviten M, Hagopian WA, Buse JB, von Herrath M, Quan J, King RS, Robinson WH, Utz PJ, Ga...> ;Sci Transl Med. 2013-06-26
• Transient B-Cell Depletion with Anti-CD20 in Combination with Proinsulin DNA Vaccine or Oral Insulin: Immunologic Effects and Efficacy in NOD Mice.
  Sarikonda, G.,Sachithanantham, S.,Manenkova, Y.,Kupfer, T.,Posgai, A.,Wasserfall, C.,Bernstein, P.,Straub, L.,Pagni, P. P.,Schneider, D.,Calvo, T. R.,Coulombe, M.,Hero...> ;PLoS ONE. 2013
• Evolution of MS lesions to black holes under DNA vaccine treatment.
  Papadopoulou A, von Felten S, Traud S, Rahman A, Quan J, King R, Garren H, Steinman L, Cutter G, Kappos L, Radue EW> ;J. Neurol.. 2012-07-01
• Multiple Sclerosis Therapies: Molecular Mechanisms and Future
  Paulo Fontoura, Hideki Garren> ;Results and problems in cell differentiation. 2010 Jan 1
• 2 citations
  A DNA vaccine for multiple sclerosis.
  Garren, H.> ;Expert opinion on biological therapy. 2008 Sep 9
• Late Pregnancy Suppresses Relapses in Experimental Autoimmune Encephalomyelitis: Evidence for a Suppressive Pregancy-Related Serum Factor
  Annette Langer-Gould, Hideki Garren, Amy Slansky, Pedro J. Ruiz, Lawrence Steinman> ;Journal of Immunology. 2002 Jul 15
• 16 citations
  DNA vaccination in the treatment of autoimmune disease.
  Garren, H., Steinman, L.> ;Current directions in autoimmunity. 2002 Jan 17
• Immunization with DNA encoding an immunodominant peptide of insulin prevents diabetes in NOD mice.
  Urbanek-Ruiz I, Ruiz PJ, Paragas V, Garren H, Steinman L, Fathman CG> ;Clin. Immunol.. 2001-08-01
• Combination of gene delivery and DNA vaccination to protect from and reverse Th1 autoimmune disease via deviation to the Th2 pathway.
  Garren H, Ruiz PJ, Watkins TA, Fontoura P, Nguyen LT, Estline ER, Hirschberg DL, Steinman L> ;Immunity. 2001-07-01
• Transglutaminase aggregates huntingtin into nonamyloidogenic polymers, and its enzymatic activity increases in Huntington's disease brain nuclei.
  Karpuj MV, Garren H, Slunt H, Price DL, Gusella J, Becher MW, Steinman L> ;Proc. Natl. Acad. Sci. U.S.A.. 1999-06-22
• Microbial epitopes act as altered peptide ligands to prevent experimental autoimmune encephalomyelitis.
  Ruiz PJ, Garren H, Hirschberg DL, Langer-Gould AM, Levite M, Karpuj MV, Southwood S, Sette A, Conlon P, Steinman L> ;J. Exp. Med.. 1999-04-19
• Suppressive immunization with DNA encoding a self-peptide prevents autoimmune disease: modulation of T cell costimulation.
  Ruiz PJ, Garren H, Ruiz IU, Hirschberg DL, Nguyen LV, Karpuj MV, Cooper MT, Mitchell DJ, Fathman CG, Steinman L> ;J. Immunol.. 1999-03-15
• Idiotypic immunization induces immunity to mutated p53 and tumor rejection.
  Ruiz PJ, Wolkowicz R, Waisman A, Hirschberg DL, Carmi P, Erez N, Garren H, Herkel J, Karpuj M, Steinman L, Rotter V, Cohen IR> ;Nat. Med.. 1998-06-01
• The specificity of the antibody response in multiple sclerosis.
  Garren H, Steinman L, Lock C> ;Ann. Neurol.. 1998-01-01
• Biological Therapeutics Research and Development--GTCbio''s Fifth Annual Conference. October 20-22, 2010, San Francisco, CA, USA.
  Garren, H.> ;IDrugs. 2010 Dec
• Gene Based Vaccines: Optimising Development and Delivery - A marcus evans Conference.
  Garren, H.> ;IDrugs. 2010 Nov
• DNA vaccines for autoimmune diseases.
  Garren, H.> ;Expert Rev Vaccines. 2009 Sep 01
• Improved efficacy of a tolerizing DNA vaccine for reversal of hyperglycemia through enhancement of gene expression and localization to intracellular sites.
  Solvason, N., Lou, Y. P., Peters, W., Evans, E., Martinez, J., Ramirez, U., Ocampo, A., Yun, R., Ahmad, S., Liu, E., Yu, L., Eisenbarth, G., Leviten, M., Steinman, L.,...> ;J Immunol. 2008 Dec 15
• Phase 2 trial of a DNA vaccine encoding myelin basic protein for multiple sclerosis.
  Garren, H., Robinson, W. H., Krasulová, E., Havrdová, E., Nadj, C., Selmaj, K., Losy, J., Nadj, I., Radue, E. W., Kidd, B. A., Gianettoni, J., Tersini, K., Utz, P. J.,...> ;Ann Neurol. 2008 May
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