HinrichStaeckerMD

PubMed

• Protection from cisplatin-induced hearing loss with lentiviral vector-mediated ectopic expression of the anti-apoptotic protein BCL-XL.
  Larissa Nassauer, Hinrich Staecker, Peixin Huang, Bryan Renslo, Madeleine Goblet, Jennifer Harre, Athanasia Warnecke, Juliane W Schott, Michael Morgan, Melanie Galla, ...> ;Molecular Therapy. Nucleic Acids. 2024 Mar 12
• Extracellular vesicles for developing targeted hearing loss therapy.
  Pan, X., Li, Y., Huang, P., He, M., Staecker, H.> ;Journal of Controlled Release. 2024 Feb 1
• CRISPR-Cas9 Engineered Extracellular Vesicles for the Treatment of Dominant Progressive Hearing Loss.
  Pan, X., Huang, P., Ali, S., Hutchinson, T., Erwin, N., Greenberg, Z., Ding, Z., Li, Y., Warnecke, A., Fernandez, N., He, M., Renslo, B., Staecker, H.> ;Biorxiv. 2023 Dec 15
• 2 citations
  Third-generation lentiviral gene therapy rescues function in a mouse model of Usher 1B.
  Juliane W Schott, Peixin Huang, Michael Morgan, Jennifer Nelson-Brantley, Ally Koehler, Bryan Renslo, Hildegard Büning, Athanasia Warnecke, Axel Schambach, Hinrich Sta...> ;Molecular Therapy. 2023 Dec 6
• QoL, CIs, QALYs, and Individualized Rehabilitation: The Clinical and Practical Benefits of Regularly Assessing the Quality of Life of Adult Cochlear Implant Recipients.
  Luis Lassaletta, Miryam Calvino, Isabel Sanchez-Cuadrado, Piotr Henryk Skarzynski, Katarzyna B Cywka, Natalia Czajka, Justyna Kutyba, Dayse Tavora-Vieira, Paul Van de ...> ;International Journal of Environmental Research and Public Health. 2023 Oct 10
• Genotype-Phenotype Correlations in TMPRSS3 (DFNB10/DFNB8) with Emphasis on Natural History.
  Eric Nisenbaum, Denise Yan, A Eliot Shearer, Evan de Joya, Torin Thielhelm, Nicole Russell, Hinrich Staecker, Zhengyi Chen, Jeffrey R Holt, Xuezhong Liu> ;Audiology & Neuro-Otology. 2023 Jan 1
• Rescue of auditory function by a single administration of AAV-TMPRSS3 gene therapy in aged mice of human recessive deafness DFNB8.
  Wan Du, Volkan Ergin, Corena Loeb, Mingqian Huang, Stewart Silver, Ariel Miura Armstrong, Zaohua Huang, Channabasavaiah B Gurumurthy, Hinrich Staecker, Xuezhong Liu, Z...> ;Molecular Therapy. 2023 Sep 6
• In Silico Localization of Perilymph Proteins Enriched in Meńier̀e Disease Using Mammalian Cochlear Single-cell Transcriptomics.
  Shoujun Gu, Athanasia Warnecke, Heike A Schmitt, Alexandra M Arambula, Hinrich Staecker, Michael Hoa> ;Otology & Neurotology Open. 2023 Mar 1
• 1 citations
  Analysis of Imaging Results for Semisitting Compared with Supine Positioning in the Retrosigmoid Approach for Resection of Cerebellopontine Angle Vestibular Schwannomas.
  Alexandra M Arambula, Helena Wichova, Jacob C Lucas, Natalie Schelbar, Nicholas Harn, Luke Ledbetter, Roukoz B Chamoun, Paul J Camarata, James Lin, Hinrich Staecker> ;Otology & Neurotology. 2023 Mar 1
• 3 citations
  Investigation of inner ear drug delivery with a cochlear catheter in piglets as a representative model for human cochlear pharmacokinetics.
  Erdem Yildiz, Anselm J Gadenstaetter, Matthias Gerlitz, Lukas D Landegger, Rudolfs Liepins, Michael Nieratschker, Rudolf Glueckert, Hinrich Staecker, Clemens Honeder, ...> ;Frontiers in Pharmacology. 2023 Jan 1
• 4 citations
  Extracellular Vesicles in Inner Ear Therapies-Pathophysiological, Manufacturing, and Clinical Considerations.
  Athanasia Warnecke, Hinrich Staecker, Eva Rohde, Mario Gimona, Anja Giesemann, Agnieszka J Szczepek, Arianna Di Stadio, Ingeborg Hochmair, Thomas Lenarz> ;Journal of Clinical Medicine. 2022 Dec 15
• 2 citations
  Evaluation of Portable Tablet-Based Audiometry in a South Indian Population.
  Sreeya Yalamanchali, Rita Ruby Albert, Hinrich Staecker, Rohit Nallani, P Naina, Kevin J Sykes> ;Indian Journal of Otolaryngology and Head and Neck Surgery. 2022 Dec 1
• 5 citations
  Single-incision cochlear implantation and hearing evaluation in piglets and minipigs.
  Erdem Yildiz, Matthias Gerlitz, Anselm Joseph Gadenstaetter, Lukas D Landegger, Michael Nieratschker, Dominic Schum, Martin Schmied, Astrid Haase, Fabian Kanz, Anne-Ma...> ;Hearing Research. 2022 Dec 1
• 2 citations
  Otopathologic and Computed Tomography Correlation of Internal Auditory Canal Diverticula in Otosclerosis.
  Dawson Wells, Renata M Knoll, Elliott Kozin, Jenny X Chen, Katherine L Reinshagen, Hinrich Staecker, Hugh D Curtin, Michael J McKenna, Joseph B Nadol Jr, Alicia M Quesnel> ;Otology & Neurotology. 2022 Oct 1
• 2 citations
  Minimally Traumatic Cochlear Implant Surgery: Expert Opinion in 2010 and 2020.
  Vedat Topsakal, Sumit Agrawal, Marcus Atlas, Wolf-Dieter Baumgartner, Kevin Brown, Iain A Bruce, Stefan Dazert, Rudolf Hagen, Luis Lassaletta, Robert Mlynski, Christop...> ;Journal of Personalized Medicine. 2022 Sep 21
• 7 citations
  Worldwide Variation in Cochlear Implant Candidacy.
  Paul Van de Heyning, Javier Gavilán, Benoît Godey, Rudolf Hagen, Abdulrahman Hagr, Mohan Kameswaran, Yongxin Li, Manikoth Manoj, Robert Mlynski, Martin O'Driscoll, Har...> ;The Journal of International Advanced Otology. 2022 May 1
• 4 citations
  Using Generic and Disease-Specific Measures to Assess Quality of Life before and after 12 Months of Hearing Implant Use: A Prospective, Longitudinal, Multicenter, Obse...
  Luis Lassaletta, Miryam Calvino, Isabel Sanchez-Cuadrado, Piotr Henryk Skarzynski, Katarzyna B Cywka, Natalia Czajka, Justyna Kutyba, Dayse Tavora-Vieira, Paul van de ...> ;International Journal of Environmental Research and Public Health. 2022 Feb 22
• 3 citations
  A Window of Opportunity: Perilymph Sampling from the Round Window Membrane Can Advance Inner Ear Diagnostics and Therapeutics.
  Madeleine St Peter, Athanasia Warnecke, Hinrich Staecker> ;Journal of Clinical Medicine. 2022 Jan 9
• 3 citations
  Olfactory, Auditory, and Vestibular Performance: Multisensory Impairment Is Significantly Associated With Incident Cognitive Impairment.
  Jacob C Lucas, Zack Arambula, Alexandra M Arambula, Katherine Yu, Nathan Farrokhian, Linda D'Silva, Hinrich Staecker, Jennifer A Villwock> ;Frontiers in Neurology. 2022 Jan 1
• 6 citations
  Suitable Electrode Choice for Robotic-Assisted Cochlear Implant Surgery: A Systematic Literature Review of Manual Electrode Insertion Adverse Events.
  Paul Van de Heyning, Peter Roland, Luis Lassaletta, Sumit Agrawal, Marcus Atlas, Wolf-Dieter Baumgartner, Kevin Brown, Marco Caversaccio, Stefan Dazert, Wolfgang Gstoe...> ;Frontiers in Surgery. 2022 Jan 1
• 3 citations
  Improving Control of Gene Therapy-Based Neurotrophin Delivery for Inner Ear Applications.
  Madeleine St Peter, Douglas E Brough, Anna Lawrence, Jennifer Nelson-Brantley, Peixin Huang, Jennifer Harre, Athanasia Warnecke, Hinrich Staecker> ;Frontiers in Bioengineering and Biotechnology. 2022 Jan 1
• 2 citations
  Bioinformatic Analysis of the Perilymph Proteome to Generate a Human Protein Atlas.
  Alina van Dieken, Hinrich Staecker, Heike Schmitt, Jennifer Harre, Andreas Pich, Willi Roßberg, Thomas Lenarz, Martin Durisin, Athanasia Warnecke> ;Frontiers in Cell and Developmental Biology. 2022 Jan 1
• 5 citations
  Successful Treatment of Noise-Induced Hearing Loss by Mesenchymal Stromal Cells: An RNAseq Analysis of Protective/Repair Pathways
  Athanasia Warnecke, Jennifer Harre, Matthew Shew, Adam J. Mellott, Igor Majewski, Martin Durisin, Hinrich Staecker> ;Frontiers in Cellular Neuroscience. 2021 Nov 23
• MicroRNA Profiling in the Perilymph of Cochlear Implant Patients: Identifying Markers that Correlate to Audiological Outcomes.
  Helena Wichova, Matthew Shew, Jennifer Nelson-Brantley, Athanasia Warnecke, Sandra Prentiss, Hinrich Staecker> ;Journal of the American Academy of Audiology. 2021 Nov 1
• 8 citations
  Isolation of sensory hair cell specific exosomes in human perilymph.
  Pei Zhuang, Suiching Phung, Athanasia Warnecke, Alexandra Arambula, Madeleine St. Peter, Mei He, Hinrich Staecker> ;Neuroscience Letters. 2021 Oct 4
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Journal Articles

• Magnetic Resonance Imaging with Cochlear Implants and Auditory Brainstem Implants: Are We Truly Practicing MRI Safety?  
  Helena Wichova, James Lin, Luke N Ledbetter, Hinrich Staecker, The Laryngoscope
• Tinnitus Perception in Patients After Vagal Nerve Stimulator Implantation for Epilepsy  
  Sameer A Alvi, Hinrich Staecker, American Journal of Otolaryngology
• Bone morphogenetic protein 4 mediates estrogen-regulated sensory axon plasticity in the adult female reproductive tract  
  Bhattacherjee A, Rumi MA, Staecker H, Smith PG, J Neurosci, 1/16/2013
• Expanding cochlear implantation to patients with residual mid and high frequency hearing  
  Rodgers, B., Prentiss, S. and Staecker, H., Otorinolaringologia, 12/1/2012
• Is hearing preservation cochlear implantation in the elderly different?  
  Staecker, H, Prentiss, S., Journal of Hearing Science, 1/1/2012
• Bcl-2 prevents hearing loss in a mouse model of sound trauma  
  Pfannenstiel, S., Praetorius M, Imig, T., Plinkert P, Brough D. E., Staecker H, Otorinolaringologia, 12/1/2011
• A Review of Gene Delivery and Stem Cell Based Therapies for Regenerating Inner Ear Hair Cells  
  Devarajan, K., Staecker, H., and Detamore, S., Journal of Functional Biomaterials, 9/1/2011
• Surgical technique in cochlear implantation  
  Praetorius M, Staecker H, Plinkert PK, HNO, 7/1/2009
• Bcl-2 gene therapy prevents aminoglycoside-induced degeneration of auditory and vestibular hair cells  
  Pfannenstiel, S., Praetorius M, Plinkert P, Brough D, Staecker H, Audiol Neurotol, 1/1/2009
• Expression patterns of non-viral transfection with GFP in the organ of Corti in vitro and in vivo Gene therapy of the inner ear with non-viral vectors] (German)  
  Praetorius M, Pfannenstiel S, Klingmann C, Baumann I, Plinkert P, Staecker H, HNO, 5/1/2008
• Topical steroid therapy using the Silverstein Microwick™ in sudden sensorineural hearing loss after failure of conventional treatment  
  Van Wijck F, Staecker H, Lefebvre PP, Acta Otolaryngol, 10/1/2007
• Pharmacodynamics of adenovector distribution within the inner ear tissues of the mouse  
  Praetorius M, Baker K, Brough D, Plinkert P, Staecker H, Hear Res, 5/1/2007
• Transynaptic delivery of nanoparticles to the central auditory nervous system  
  Praetorius M, Brunner C, Lehnert B, Klingmann C, Schmidt H, Staecker H, Schick B, Acta Otolaryngol, 5/1/2007
• Vestibular hair cell regeneration and restoration of balance function induced by math1 gene transfer  
  Staecker H, Praetorius M, Baker K, Brough D, Otol Neurotol, 2/1/2007
• Vector-mediated delivery of bcl-2 prevents degeneration of auditory hair cells and neuroma after injury  
  Staecker H, Liu W, Malgrange B, Lefebvre PP, Van De Water TR, ORL J Otorhinolaryngol Relat Spec, 1/1/2007
• An overview of animal models of tinnitus  
  Ursick J, Staecker H, B-ENT, 1/1/2007
• [ASA and the inner ear: An old acquaintance in a new light] (Review, German)  
  Praetorius M, Staecker H, HNO, 9/1/2006
• Local perfusion of necrosis factor alpha blocker infliximab to the inner ear improves autoimmune neurosensory hearing loss  
  Van Wijk F, Staecker H, Keithley E, Lefebvre PP, Audiol Neurooto, 1/1/2006
• The last myrmidon: The life, legacy, and fatal ear disorder of Heinrich Schliemann  
  Staecker H, Easton D, Mackowiak P, Pharos Alpha Omega Alpha Honor Med Soc, 1/1/2006
• Nonorganic hearing loss  
  Lin J. Staecker H., Semin Neurol, 1/1/2006
• Advances in inner ear gene therapy: exploring cochlear protection and regeneration  
  Maiorana C, Staecker H, Curr Opin Otolaryngol Head Neck Surg, 10/1/2005
• Broadening the spectrum of treatment options for SNHL (Review)  
  Staecker H, Arch Otolaryngol Head Neck Surg, 8/1/2005
• Drug delivery to the inner ear using gene therapy (Review)  
  Staecker H, Brough D, Praetorius M, Baker K, Otolaryngol Clin North Am, 10/1/2004
• Caspases, the enemy within, and their role in oxidative stress-induced apoptosis of inner ear sensory cells (Review)  
  Van De Water TR, Lallemend F, Eshraghi AA, Ahsan S, He J, Guzman J, Polak M, Malgrange B, Lefebvre, PP, Staecker H, Balkany, TJ, Otol Neurotol, 7/1/2004
• Extended pericranial flap and bone graft reconstruction in anterior skull base surgery  
  Rodrigues M, O'Malley B, Staecker H, Tamargo R, Otolaryngol Head Neck Surg, 7/1/2004
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Lectures

• Prevalence of Vestibular Pathology in People with Type 2 Diabetes 
  Kansas City, KS - 6/15/2014