HirotoInabaMD

PubMed

• Single-cell systems pharmacology identifies development-driven drug response and combination therapy in B cell acute lymphoblastic leukemia.
  Xin Huang, Yizhen Li, Jingliao Zhang, Lei Yan, Huanbin Zhao, Liang Ding, Sheetal Bhatara, Xu Yang, Satoshi Yoshimura, Wenjian Yang, Seth E Karol, Hiroto Inaba, Charles...> ;Cancer Cell. 2024 Apr 8
• Quantitative computed tomography analysis of body composition changes in paediatric patients with acute lymphoblastic leukaemia.
  Zhuang, T., Kunanya Suwannaying, Adrian A Ong, Rikeenkumar Dhaduk, Deqing Pei, Mayuko Iijima, Eric Merkle, Tony Z Zhuang, Chelsea G Goodenough, Joren Brown, Emily K Br...> ;British Journal of Haematology. 2024 Apr 1
• Germline Genetic NBN Variation and Predisposition to B-cell Acute Lymphoblastic Leukemia in Children.
  Carolin S Escherich, Wenan Chen, Yizhen Li, Wenjian Yang, Rina Nishii, Zhenhua Li, Elizabeth A Raetz, Meenakshi Devidas, Gang Wu, Kim E Nichols, Hiroto Inaba, Ching-Ho...> ;Blood. 2024 Mar 6
• Genomic and global gene expression profiling in pediatric and young adult acute leukemia with PICALM::MLLT10 Fusion.
  Jingqun Ma, Yen-Chun Liu, Rebecca K Voss, Jing Ma, Ajay Palagani, Elizabeth Caldwell, Wojciech Rosikiewicz, Maria Cardenas, Scott Foy, Masayuki Umeda, Mark R Wilkinson...> ;Leukemia. 2024 Mar 1
• Ommaya reservoir use in pediatric ALL and NHL: a review at St. Jude Children's Research Hospital.
  Alyssa Gaietto, John C Panetta, Jennifer L Pauley, Mary V Relling, Raul Ribeiro, Matthew J Ehrhardt, Ching-Hon Pui, Hiroto Inaba, Hope D Swanson> ;Cancer Chemotherapy and Pharmacology. 2024 Feb 28
• 1 citations
  COVID-19 in Pediatric Patients With Acute Lymphoblastic Leukemia or Lymphoma.
  Bodea, J., Patni, T., Angel, S., Wolf, J., Li, Y., Hashmi, S., Bhakta, N., Jeha, S., Karol, S., Ribeiro, R., Rubnitz, J., Pui, C., Hijano, D., Inaba, H.> ;JAMA Network Open. 2024 Feb 5
• Additive effects of TPMT and NUDT15 on thiopurine toxicity in children with acute lymphoblastic leukemia across multiethnic populations.
  Maillard, M., Nishii, R., Yang, W., Hoshitsuki, K., Chepyala, D., Lee, S., Nguyen, J., Relling, M., Crews, K., Leggas, M., Singh, M., Suang, J., Yeoh, A., Jeha, S., In...> ;Journal of the National Cancer Institute. 2024 Jan 16
• Cough, Neck Pain, and Right Facial Paralysis in a 14-year-old with Autism.
  Zhongbo Hu, Bradley Muller, Jeremy S Slone, Hiroto Inaba> ;Pediatrics in Review. 2024 Jan 1
• 1 citations
  Epigenomic mapping reveals distinct B cell acute lymphoblastic leukemia chromatin architectures and regulators.
  Kelly R Barnett, Robert J Mobley, Jonathan D Diedrich, Brennan P Bergeron, Kashi Raj Bhattarai, Alexander C Monovich, Shilpa Narina, Wenjian Yang, Kristine R Crews, Ch...> ;Cell Genomics. 2023 Dec 13
• Chimeric antigen receptor T-cells in B-acute lymphoblastic leukemia: history, current situation, and future.
  Bradley J Muller, Hiroto Inaba> ;Translational Pediatrics. 2023 Oct 30
• Prognostic and Pharmacotypic Heterogeneity of Hyperdiploidy in Childhood ALL.
  Shawn H R Lee, Emily Ashcraft, Wenjian Yang, Kathryn G Roberts, Yoshihiro Gocho, Lauren Rowland, Hiroto Inaba, Seth E Karol, Sima Jeha, Kristine R Crews, Charles G Mul...> ;Journal of Clinical Oncology. 2023 Dec 10
• CD19 CAR T-cell therapy demonstrates activity against extramedullary disease in pediatric patients with B-ALL.
  Rebecca Epperly, Barry L Shulkin, Asim K Bag, Cheng Cheng, Hiroto Inaba, John T Lucas, Swati Naik, Brandon M Triplett, Stephen Gottschalk, Aimee C Talleur> ;Blood Advances. 2023 Oct 24
• 2 citations
  Rituximab administration in pediatric patients with newly diagnosed acute lymphoblastic leukemia.
  Keito Hoshitsuki, Yinmei Zhou, April M Miller, John K Choi, Hope D Swanson, Nickhill H Bhakta, Sima Jeha, Seth E Karol, Raul C Ribeiro, Jeffrey E Rubnitz, Charles G Mu...> ;Leukemia. 2023 Sep 1
• Ex vivo Drug Sensitivity Imaging-based Platform for Primary Acute Lymphoblastic Leukemia Cells.
  Lauren Rowland, Brandon Smart, Anthony Brown, Gino M Dettorre, Yoshihiro Gocho, Jeremy Hunt, Wenjian Yang, Satoshi Yoshimura, Noemi Reyes, Guoqing Du, August John, Dyl...> ;Bio-Protocol. 2023 Aug 5
• 1 citations
  Acute Lymphoblastic Leukemia with Central Nervous System Involvement-Challenges in Management.
  Shruthi Suryaprakash, Hiroto Inaba> ;Indian Journal of Pediatrics. 2024 Jan 1
• Germline GeneticVariation and Predisposition to B-cell Acute Lymphoblastic Leukemia in Children.
  Carolin Escherich, Wenan Chen, Yizhen Li, Wenjian Yang, Rina Nishii, Zhenhua Li, Elizabeth A Raetz, Meenakshi Devidas, Gang Wu, Kim E Nichols, Hiroto Inaba, Ching-Hon ...> ;Research Square. 2023 Jul 21
• 1 citations
  Epigenomic mapping in B-cell acute lymphoblastic leukemia identifies transcriptional regulators and noncoding variants promoting distinct chromatin architectures.
  Kelly R Barnett, Robert J Mobley, Jonathan D Diedrich, Brennan P Bergeron, Kashi Raj Bhattarai, Wenjian Yang, Kristine R Crews, Christopher S Manring, Elias Jabbour, E...> ;Biorxiv. 2023 Jul 13
• Genomic analysis of venous thrombosis in children with acute lymphoblastic leukemia from diverse ancestries.
  Yan Zheng, Wenjian Yang, Jeremie Estepp, Deqing Pei, Cheng Cheng, Clifford M Takemoto, Hiroto Inaba, Sima Jeha, Ching-Hon Pui, Mary V Relling, Seth E Karol> ;Haematologica. 2024 Jan 1
• 1 citations
  Clinical impact of minimal residual disease in blood and bone marrow of children with acute myeloid leukemia.
  Seth E Karol, Elaine Coustan-Smith, Stanley Pounds, Lei Wang, Hiroto Inaba, Raul C Ribeiro, Ching-Hon Pui, Jeffery M Klco, Jeffrey E Rubnitz> ;Blood Advances. 2023 Jul 25
• Clinical characteristics and outcomes of children with newly diagnosed acute myeloid leukemia and hyperleukocytosis managed with different cytoreductive methods.
  Georgios E Christakopoulos, Kendra N Walker, Jesse Smith, Clifford M Takemoto, Yan Zheng, Ching-Hon Pui, Raul C Ribeiro, Lei Wang, Stanley B Pounds, Jeffrey E Rubnitz,...> ;Cancer. 2023 Jun 15
• Author Correction: Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia.
  Jennifer L Kamens, Stephanie Nance, Cary Koss, Beisi Xu, Anitria Cotton, Jeannie W Lam, Elizabeth A R Garfinkle, Pratima Nallagatla, Amelia M R Smith, Sharnise Mitchel...> ;Nature Communications. 2023 Mar 9
• 6 citations
  Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia.
  Jennifer L Kamens, Stephanie Nance, Cary Koss, Beisi Xu, Anitria Cotton, Jeannie W Lam, Elizabeth A R Garfinkle, Pratima Nallagatla, Amelia M R Smith, Sharnise Mitchel...> ;Nature Communications. 2023 Feb 13
• 18 citations
  Pharmacotypes across the genomic landscape of pediatric acute lymphoblastic leukemia and impact on treatment response.
  Shawn H R Lee, Wenjian Yang, Yoshihiro Gocho, August John, Lauren Rowland, Brandon Smart, Hannah Williams, Dylan Maxwell, Jeremy Hunt, Wentao Yang, Kristine R Crews, K...> ;Nature Medicine. 2023 Jan 1
• 21 citations
  Engineering naturally occurring CD7- T cells for the immunotherapy of hematological malignancies.
  Velasquez, P., Velasquez, P., Abdullah Freiwan, Jaquelyn T Zoine, Jeremy Chase Crawford, Abishek Vaidya, Stefan A Schattgen, Jacquelyn A Myers, Sagar L Patil, Mahsa Kh...> ;Blood. 2022 Dec 22
• 7 citations
  PAX5 epigenetically orchestrates CD58 transcription and modulates blinatumomab response in acute lymphoblastic leukemia.
  Yizhen Li, Takaya Moriyama, Satoshi Yoshimura, Xujie Zhao, Zhenhua Li, Xu Yang, Elisabeth Paietta, Mark R Litzow, Marina Konopleva, Jiyang Yu, Hiroto Inaba, Raul C Rib...> ;Science Advances. 2022 Dec 14
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Journal Articles

• Association of Bacteremic Sepsis with Long-Term Neurocognitive Dysfunction in Pediatric Patients with Acute Lymphoblastic Leukemia  
  Hiroto Inaba, Joshua Wolf, Kevin R Krull, Melissa M Hudson, JAMA

Abstracts/Posters

• Acute Lymphoblastic Leukemia with Zinc-Finger Protein 384 (ZNF384)-Related Rearrangements: A Retrospective Analysis from the Ponte Di Legno Childhood ALL Working Group
  Hiroto Inaba, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019

Lectures

• Traumatic and Bloody Lumbar Puncture at Diagnosis in Children with Acute Lymphoblastic Leukemia: A St. Jude Total XV and Total Xvi Cohort Study 
  2018 ASH Annual Meeting - San Diego, CA - 12/1/2018