HongYuMD

PubMed

• 1 citations
  The natural history of ALS: Baseline characteristics from a multicenter clinical cohort.
  Alex Berger, Matteo Locatelli, Ximena Arcila-Londono, Ghazala Hayat, Nicholas Olney, James Wymer, Kelly Gwathmey, Christian Lunetta, Terry Heiman-Patterson, Senda Ajro...> ;Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 2023 Jul 17
• 2 citations
  Design and Statistical Innovations in a Platform Trial for Amyotrophic Lateral Sclerosis.
  Melanie Quintana, Benjamin R Saville, Matteo Vestrucci, Michelle A Detry, Lori Chibnik, Jeremy Shefner, James D Berry, Marianne Chase, Jinsy Andrews, Alexander V Sherm...> ;Annals of Neurology. 2023 Sep 1
• 1 citations
  Expanded access protocol (EAP) program for access to investigational products for amyotrophic lateral sclerosis (ALS).
  Megan Yerton, Allison Winter, Dario Gelevski, Grace Addy, Anthony Kostov, Cassandra Lieberman, Harli Weber, Michael Doyle, Geli Kane, Caroline Cohen, Neil Parikh, Kath...> ;Muscle & Nerve. 2023 Jun 1
• 4 citations
  Randomized trial of inosine for urate elevation in amyotrophic lateral sclerosis.
  David Walk, Katharine Nicholson, Eduardo Locatelli, James Chan, Eric A Macklin, Valerie Ferment, Georgios Manousakis, Marianne Chase, Mariah Connolly, Derek Dagostino,...> ;Muscle & Nerve. 2023 May 1
• 1 citations
  Safety and activity of anti-CD14 antibody IC14 (atibuclimab) in ALS: Experience with expanded access protocol.
  Dario Gelevski, Grace Addy, Margot Rohrer, Caroline Cohen, Aimee Roderick, Allison Winter, Judith Carey, Jennifer Scalia, Megan Yerton, Harli Weber, Michael Doyle, Nei...> ;Muscle & Nerve. 2023 May 1
• 5 citations
  An expanded access protocol of RT001 in amyotrophic lateral sclerosis-Initial experience with a lipid peroxidation inhibitor.
  Megan Yerton, Allison Winter, Anthony Kostov, Cassandra Lieberman, Dario Gelevski, Harli Weber, Michael Doyle, Geli Kane, Neil Parikh, Katherine M Burke, Margot Rohrer...> ;Muscle & Nerve. 2022 Oct 1
• 45 citations
  Transplantation of human neural progenitor cells secreting GDNF into the spinal cord of patients with ALS: a phase 1/2a trial.
  Robert H Baloh, J Patrick Johnson, Pablo Avalos, Peggy Allred, Soshana Svendsen, Genevieve Gowing, Kristina Roxas, Amanda Wu, Becky Donahue, Sheryl Osborne, George Law...> ;Nature Medicine. 2022 Sep 1
• 30 citations
  Effect of sodium phenylbutyrate/taurursodiol on tracheostomy/ventilation-free survival and hospitalisation in amyotrophic lateral sclerosis: long-term results from the...
  Sabrina Paganoni, Suzanne Hendrix, Samuel P Dickson, Newman Knowlton, James D Berry, Michael A Elliott, Samuel Maiser, Chafic Karam, James B Caress, Margaret Ayo Owegi...> ;Journal of Neurology, Neurosurgery, and Psychiatry. 2022 May 16
• 35 citations
  Adaptive Platform Trials to Transform Amyotrophic Lateral Sclerosis Therapy Development.
  Sabrina Paganoni, James D Berry, Melanie Quintana, Eric Macklin, Benjamin R Saville, Michelle A Detry, Marianne Chase, Alexander V Sherman, Hong Yu, Kristin Drake, Jin...> ;Annals of Neurology. 2022 Feb 1
• 50 citations
  Answer ALS, a large-scale resource for sporadic and familial ALS combining clinical and multi-omics data from induced pluripotent cell lines.
  Emily G Baxi, Terri Thompson, Jonathan Li, Julia A Kaye, Ryan G Lim, Jie Wu, Divya Ramamoorthy, Leandro Lima, Vineet Vaibhav, Andrea Matlock, Aaron Frank, Alyssa N Coy...> ;Nature Neuroscience. 2022 Feb 1
• 89 citations
  Long-term survival of participants in the CENTAUR trial of sodium phenylbutyrate-taurursodiol in amyotrophic lateral sclerosis
  Sabrina Paganoni, Suzanne Hendrix, Samuel P. Dickson, Newman Knowlton, Eric A. Macklin, James D. Berry, Michael A. Elliott, Samuel Maiser, Chafic Karam, James B. Cares...> ;Muscle & Nerve. 2021 Jan 1
• 208 citations
  Trial of Sodium Phenylbutyrate–Taurursodiol for Amyotrophic Lateral Sclerosis
  Sabrina Paganoni, Eric A. Macklin, Suzanne Hendrix, James D. Berry, Michael A. Elliott, Samuel Maiser, Chafic Karam, James B. Caress, Margaret A. Owegi, Adam Quick, Ja...> ;The New England Journal of Medicine. 2020 Sep 2
• 12 citations
  NACHO Engages N-Glycosylation ER Chaperone Pathways for α7 Nicotinic Receptor Assembly.
  Hae-Jin Kweon, Shenyan Gu, Emily Witham, Madhurima Dhara, Hong Yu, Elodie Desuzinges Mandon, Anass Jawhari, David S. Bredt> ;Cell Reports. 2020 Aug 11
• 27 citations
  Polyamine regulation of ion channel assembly and implications for nicotinic acetylcholine receptor pharmacology.
  Madhurima Dhara, Jose A. Matta, Min Lei, Daniel Knowland, Hong Yu, Shenyan Gu, David S. Bredt> ;Nature Communications. 2020 Jun 3
• 10 citations
  Selection design phase II trial of high dosages of tamoxifen and creatine in amyotrophic lateral sclerosis.
  Suma Babu, Eric A. Macklin, Katherine E. Jackson, Elizabeth Simpson, Katy Mahoney, Hong Yu, Jason Walker, Zachary Simmons, William S. David, Paul E. Barkhaus, Laura Si...> ;Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 2020 Jan 2
• 21 citations
  α7 nicotinic acetylcholine receptor upregulation by anti-apoptotic Bcl-2 proteins
  G. Brent Dawe, Hong Yu, Shenyan Gu, Alissa N. Blackler, Jose A. Matta, Edward R. Siuda, Elizabeth B. Rex, David S. Bredt> ;Nature Communications. 2019 Jun 21
• Towards Drug Safety Surveillance and Pharmacovigilance: Current Progress in Detecting Medication and Adverse Drug Events from Electronic Health Records.
  Liu, F.,Jagannatha, A.,Yu, H.> ;Drug Saf. 2019 Jan 17
• 38 citations
  A randomized controlled trial of resistance and endurance exercise in amyotrophic lateral sclerosis
  Lora Clawson, Merit Cudkowicz, Lisa S. Krivickas, Benjamin Rix Brooks, Mohammed Sanjak, Peggy Allred, Nazem Atassi, Amy Swartz, Gabrielle Steinhorn, Alpa Uchil, Kriste...> ;Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 2018 Apr 3
• Anti-mitotic chemotherapeutics promote apoptosis through TL1A-activated death receptor 3 in cancer cells.
  Qi, C.,Wang, X.,Shen, Z.,Chen, S.,Yu, H.,Williams, N.,Wang, G.> ;Cell Res.. 2018 Mar 03
• 13 citations
  Vitamin D levels are associated with gross motor function in amyotrophic lateral sclerosis.
  Sabrina Paganoni, Eric A. Macklin, Chafic Karam, Hong Yu, Fernando Gonterman, K. Ashley Fetterman, Merit Cudkowicz, James D. Berry, Anne-Marie Wills> ;Muscle & Nerve. 2017 Oct 1
• 59 citations
  Enhanced Bulbar Function in Amyotrophic Lateral Sclerosis: The Nuedexta Treatment Trial.
  Richard Smith, Erik P. Pioro, Kathleen Myers, Michael Sirdofsky, Kimberly Goslin, Gregg Meekins, Hong Yu, James Wymer, Merit Cudkowicz, Eric A. Macklin, David A. Schoe...> ;Neurotherapeutics. 2017 Jul 1
• 1 citations
  Erratum to: Enhanced Bulbar Function in Amyotrophic Lateral Sclerosis: The Nuedexta Treatment Trial.
  Richard Smith, Erik P. Pioro, Kathleen Myers, Michael Sirdofsky, Kimberly Goslin, Gregg Meekins, Hong Yu, James Wymer, Merit Cudkowicz, Eric A. Macklin, David A. Schoe...> ;Neurotherapeutics. 2017 Jul 1
• 64 citations
  Forebrain-selective AMPA-receptor antagonism guided by TARP γ-8 as an antiepileptic mechanism
  Akihiko Kato, Kevin D. Burris, Kevin Matthew Gardinier, Douglas Linn Gernert, Warren J. Porter, Jon K. Reel, Chunjin Ding, Yuan Tu, Douglas A. Schober, Matthew Lee, Be...> ;Nature Medicine. 2016 Dec 1
• 40 citations
  Discovery of the First α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (T...
  Kevin Matthew Gardinier, Douglas Linn Gernert, Warren J. Porter, Jon K. Reel, Paul L. Ornstein, Patrick Gianpietro Spinazze, F. Craig Stevens, Patric James Hahn, Sean ...> ;Journal of Medicinal Chemistry. 2016 Apr 29
• 37 citations
  Porcupine Controls Hippocampal AMPAR Levels, Composition, and Synaptic Transmission
  Nadine Erlenhardt, Hong Yu, Kavitha Abiraman, Tokiwa Yamasaki, Jacques I. Wadiche, Susumu Tomita, David S. Bredt> ;Cell Reports. 2016 Feb 2
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