HowardYuan-HaoChangMD

PubMed

• Extrachromosomal DNA in cancer.
  Xiaowei Yan, Paul Mischel, Howard Chang> ;Nature Reviews. Cancer. 2024 Apr 1
• 6 citations
  Xist ribonucleoproteins promote female sex-biased autoimmunity.
  Diana R Dou, Yanding Zhao, Julia A Belk, Yang Zhao, Kerriann M Casey, Derek C Chen, Rui Li, Bingfei Yu, Suhas Srinivasan, Brian T Abe, Katerina Kraft, Ceke Hellström, ...> ;Cell. 2024 Feb 1
• 7 citations
  The AAV capsid can influence the epigenetic marking of rAAV delivered episomal genomes in a species dependent manner.
  Adriana Gonzalez-Sandoval, Katja Pekrun, Shinnosuke Tsuji, Feijie Zhang, King L Hung, Howard Y Chang, Mark A Kay> ;Nature Communications. 2023 Apr 28
• 7 citations
  First-in-Human Assessment of Feasibility and Safety of Multiplexed Genetic Engineering of Autologous T Cells Expressing NY-ESO -1 TCR and CRISPR/Cas9 Gene Edited to El...
  Edward A. Stadtmauer, Adam D. Cohen, Kristy L. Weber, Simon F. Lacey, Vanessa E. Gonzalez, J. Joseph Melenhorst, Joseph A. Fraietta, Gabriela Plesa, Joanne Shea, Tina ...> ;Blood. 2019 Nov 13
• Enhancer Connectome Nominates Target Genes of Inherited Risk Variants from Inflammatory Skin Disorders
  Mark Y Jeng, Howard Y Chang, Ansuman T Satpathy> ;The Journal of Investigative Dermatology. 2018 Oct 14
• HiChIRP reveals RNA-associated chromosome conformation.
  Mumbach, M. R.,Granja, J. M.,Flynn, R. A.,Roake, C. M.,Satpathy, A. T.,Rubin, A. J.,Qi, Y.,Jiang, Z.,Shams, S.,Louie, B. H.,Guo, J. K.,Gennert, D. G.,Corces, M. R.,Kha...> ;Nat. Methods. 2019 May 28
• RNA structure maps across mammalian cellular compartments.
  Sun, L.,Fazal, F. M.,Li, P.,Broughton, J. P.,Lee, B.,Tang, L.,Huang, W.,Kool, E. T.,Chang, H. Y.,Zhang, Q. C.> ;Nat. Struct. Mol. Biol.. 2019 Mar 20
• A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells.
  Van Gool, F.,Nguyen, MLT.,Mumbach, M. R.,Satpathy, A. T.,Rosenthal, W. L.,Giacometti, S.,Le, D. T.,Liu, W.,Brusko, T. M.,Anderson, M. S.,Rudensky, A. Y.,Marson, A.,Cha...> ;Immunity. 2019 Feb 03
• TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment.
  Li, L.,Wang, Y.,Torkelson, J. L.,Shankar, G.,Pattison, J. M.,Zhen, H. H.,Fang, F.,Duren, Z.,Xin, J.,Gaddam, S.,Melo, S. P.,Piekos, S. N.,Li, J.,Liaw, E. J.,Chen, L.,Li...> ;Cell Stem Cell. 2019 Jan 29
• The RNA Base-Pairing Problem and Base-Pairing Solutions.
  Lu, Z.,Chang, H. Y.> ;Cold Spring Harb Perspect Biol. 2018 Dec 05
• Coupled Single-Cell CRISPR Screening and Epigenomic Profiling Reveals Causal Gene Regulatory Networks.
  Rubin, A. J.,Parker, K. R.,Satpathy, A. T.,Qi, Y.,Wu, B.,Ong, A. J.,Mumbach, M. R.,Ji, A. L.,Kim, D. S.,Cho, S. W.,Zarnegar, B. J.,Greenleaf, W. J.,Chang, H. Y.,Khavar...> ;Cell. 1900 Jan 01
• Retinoic acid and BMP4 cooperate with p63 to alter chromatin dynamics during surface epithelial commitment.
  Pattison, J. M.,Melo, S. P.,Piekos, S. N.,Torkelson, J. L.,Bashkirova, E.,Mumbach, M. R.,Rajasingh, C.,Zhen, H. H.,Li, L.,Liaw, E.,Alber, D.,Rubin, A. J.,Shankar, G.,B...> ;Nat. Genet.. 2018 Nov 07
• Mechanoresponsive stem cells acquire neural crest fate in jaw regeneration.
  Ransom, R. C.,Carter, A. C.,Salhotra, A.,Leavitt, T.,Marecic, O.,Murphy, M. P.,Lopez, M. L.,Wei, Y.,Marshall, C. D.,Shen, E. Z.,Jones, R. E.,Sharir, A.,Klein, O. D.,Ch...> ;Nature. 2018 Oct 26
• Identification of the Human Skeletal Stem Cell
  Howard Y. Chang, Ravindra Majeti, Julius Bishop, Michael T. Longaker, Michael Gardner, Charles K.F. Chan> ;Cell Press. 2018 Sep 23
• ChIRP-MS: RNA-Directed Proteomic Discovery.
  Chu, C.,Chang, H. Y.> ;Methods Mol. Biol.. 2018 Sep 16
• A Chromatin Basis for Cell Lineage and Disease Risk in the Human Pancreas.
  Arda, H. E.,Tsai, J.,Rosli, Y. R.,Giresi, P.,Bottino, R.,Greenleaf, W. J.,Chang, H. Y.,Kim, S. K.> ;Cell Syst. 2018 Aug 27
• HASH(0x236d9a0)
  Huang, W.,Thomas, B.,Flynn, R. A.,Gavzy, S. J.,Wu, L.,Kim, S. V.,Hall, J. A.,Miraldi, E. R.,Ng, C. P.,Rigo, F.,Meadows, S.,Montoya, N. R.,Herrera, N. G.,Domingos, A. I...> ;Nature. 2018 Jul 06
• Expression of the Transcription Factor ZBTB46 Distinguishes Human Histiocytic Disorders of Classical Dendritic Cell Origin
  Zenggang Pan, Yasodha Natkunam, Howard Y Chang, Ansuman T Satpathy, Ryanne A Brown> ;Nature.
• ATAC Primer Tool for Targeted Analysis of Accessible Chromatin
  Howard Y Chang, Howard Y Chang> ;Nature.
• An Activity Switch in Human Telomerase Based on RNA Conformation and Shaped by TCAB1
  Steven E Artandi, Andrew S Venteicher, Howard Y Chang, Caitlin M Roake> ;Cell Press.
• Transcript-Indexed ATAC-Seq for Precision Immune Profiling
  Michael S Khodadoust, Paul A Khavari, Ansuman T Satpathy, Howard Y Chang> ;Nature.
• Rapid Chromatin Repression by Aire Provides Precise Control of Immune Tolerance
  Howard Y Chang, David M Moskowitz> ;Nature. 1900 Jan 01
• Tissue-selective effects of nucleolar stress and rDNA damage in developmental disorders.
  Calo, E.,Gu, B.,Bowen, M. E.,Aryan, F.,Zalc, A.,Liang, J.,Flynn, R. A.,Swigut, T.,Chang, H. Y.,Attardi, L. D.,Wysocka, J.> ;Nature. 2018 Jan 25
• m6A mRNA methylation sustains Treg suppressive functions.
  Tong, J.,Cao, G.,Zhang, T.,Sefik, E.,Amezcua Vesely, M. C.,Broughton, J. P.,Zhu, S.,Li, H.,Li, B.,Chen, L.,Chang, H. Y.,Su, B.,Flavell, R. A.,Li, H. B.> ;Cell Res.. 2018 Jan 06
• Challenges and recommendations for epigenomics in precision health.
  Carter, A. C.,Chang, H. Y.,Church, G.,Dombkowski, A.,Ecker, J. R.,Gil, E.,Giresi, P. G.,Greely, H.,Greenleaf, W. J.,Hacohen, N.,He, C.,Hill, D.,Ko, J.,Kohane, I.,Kunda...> ;Nat. Biotechnol.. 2017 Dec 09
• Join now to see all