HowardDavidsonMD

PubMed

• 5 citations
  Inherent Beta Cell Dysfunction Contributes to Autoimmune Susceptibility
  Yong Kyung Kim, Lori Sussel, Howard W. Davidson> ;Biomolecules. 2021 Mar 30
• 3 citations
  Immune therapies for autoimmune diabetes targeting pathogenic peptide-MHC complexes.
  Howard W. Davidson, Li Zhang> ;Journal of Molecular Cell Biology. 2020 Oct 1
• 5 citations
  A monoclonal antibody with broad specificity for the ligands of insulin B:9-23 reactive T cells prevents spontaneous type 1 diabetes in mice.
  Joseph Ray Cepeda, Nitin S Sekhar, Junying Han, Wei Xiong, Ningyan Zhang, Liping Yu, Shaodong Dai, Howard W. Davidson, John W. Kappler, Zhiqiang An, Li Zhang> ;Mabs. 2020 Jan 1
• 10 citations
  Autoantibodies Toward ATP4A and ATP4B Subunits of Gastric Proton Pump H+,K+-ATPase Are Reliable Serological Pre-endoscopic Markers of Corpus Atrophic Gastritis.
  Edith Lahner, Ilaria Marzinotto, Vito Lampasona, Ludovica Dottori, Elena Bazzigaluppi, Cristina Brigatti, Massimiliano Secchi, Lorenzo Piemonti, Laura Conti, Emanuela ...> ;Clinical and Translational Gastroenterology. 2020 Oct 1
• 24 citations
  ZIGIR, a Granule-Specific Zn2+ Indicator, Reveals Human Islet α Cell Heterogeneity
  Ebrahim H. Ghazvini Zadeh, Zhi Jiang Huang, Jing Xia, Daliang Li, Howard W. Davidson, Wen Hong Li> ;Cell Reports. 2020 Jul 14
• High-Efficiency Generation of Antigen-Specific Primary Mouse Cytotoxic T Cells for Functional Testing in an Autoimmune Diabetes Model
  Howard W. Davidson, Joseph Ray Cepeda, Nitin S Sekhar, Junying Han, Ling Gao, Tomasz Sosinowski, Li Zhang> ;Journal of Visualized Experiments. 2019 Aug 16
• 9 citations
  Autoantibodies Directed Toward a Novel IA-2 Variant Protein Enhance Prediction of Type 1 Diabetes
  Maria Acevedo-Calado, Susan L. Pietropaolo, Michael P. Morran, Santiago Schnell, Andrew D Vonberg, Charles F. Verge, Roberto Gianani, Dorothy J. Becker, Shuai Huang, C...> ;Diabetes. 2019 Jun 5
• How C-terminal additions to insulin B-chain fragments create superagonists for T cells in mouse and human type 1 diabetes.
  Wang, Y.,Sosinowski, T.,Novikov, A.,Crawford, F.,White, J.,Jin, N.,Liu, Z.,Zou, J.,Neau, D.,Davidson, H. W.,Nakayama, M.,Kwok, W. W.,Gapin, L.,Marrack, P.,Kappler, J. ...> ;Sci Immunol. 2019 Apr 07
• 49 citations
  Chimeric antigen receptor (CAR) T cells targeting a pathogenic MHC class II:peptide complex modulate the progression of autoimmune diabetes.
  Li Zhang, Tomasz Sosinowski, Aaron R. Cox, Joseph Ray Cepeda, Nitin S Sekhar, Sean M. Hartig, Dongmei Miao, Liping Yu, Massimo Pietropaolo, Howard W. Davidson> ;Journal of Autoimmunity. 2019 Jan 1
• 5 citations
  Measurement of Autoantibodies to Gastric H+,K+-ATPase (ATP4A/B) Using a Luciferase Immunoprecipitation System (LIPS).
  Edith Lahner, Ilaria Marzinotto, Cristina Brigatti, Howard W. Davidson, Janet M. Wenzlau, Lorenzo Piemonti, Bruno Annibale, Vito Lampasona> ;Methods in Molecular Biology. 2019 Jan 1
• 18 citations
  Development of T cell lines sensitive to antigen stimulation.
  Theodore Williams, Harsha Krovi, Laurie G. Landry, Frances Crawford, Niyun Jin, Anita Hohenstein, Megan E DeNicola, Aaron W. Michels, Howard W. Davidson, Sally C. Kent...> ;Journal of Immunological Methods. 2018 Aug 28
• 33 citations
  A quarter of patients with type 1 diabetes have co-existing non-islet autoimmunity: the findings of a UK population-based family study.
  Aizhan Kozhakhmetova, Rebecca Wyatt, Claire H Caygill, Claire L Williams, Anna E. Long, Kyla Chandler, Rachel J Aitken, Janet M. Wenzlau, Howard W. Davidson, Kathleen ...> ;Clinical and Experimental Immunology. 2018 Jun 1
• 185 citations
  Islet-reactive CD8+ T cell frequencies in the pancreas, but not in blood, distinguish type 1 diabetic patients from healthy donors
  Slobodan Culina, Ana Inés Lalanne, Georgia Afonso, Karen Cerosaletti, Sheena Pinto, Guido Sebastiani, Klaudia Kuranda, Laura Nigi, Anne Eugster, Thomas Osterbye, Alici...> ;Science Immunology. 2018 Feb 2
• 4 citations
  ATP4A autoimmunity in pediatric patients with type 1 diabetes and its relationship to blood count, iron metabolism, and vitamin B12.
  Agata Chobot, Ewa Rusak, Janet M. Wenzlau, Howard W. Davidson, Piotr Adamczyk, Agnieszka Krzywicka, Bogdan Mazur, Joanna Polanska, Marian Rewers> ;Pediatric Diabetes. 2018 Feb 1
• 17 citations
  Combinatorial detection of autoreactive CD8+ T cells with HLA-A2 multimers: a multi-centre study by the Immunology of Diabetes Society T Cell Workshop
  Eddie A. James, Joana R. F. Abreu, John W. McGinty, Jared M. Odegard, Yvonne E. Fillié, Claire N. Hocter, Slobodan Culina, Kristin Ladell, David Price, Aimon K. Alkana...> ;Diabetologia. 2018 Mar 1
• 17 citations
  Luminescent Immunoprecipitation System (LIPS) for Detection of Autoantibodies Against ATP4A and ATP4B Subunits of Gastric Proton Pump H+,K+-ATPase in Atrophic Body Gas...
  Edith Lahner, Cristina Brigatti, Ilaria Marzinotto, Marilia Carabotti, Giulia Scalese, Howard W. Davidson, Janet M. Wenzlau, Emanuele Bosi, Lorenzo Piemonti, Bruno Ann...> ;Clinical and Translational Gastroenterology. 2017 Jan 19
• 18 citations
  Characterization of immune response to novel HLA-A2-restricted epitopes from zinc transporter 8 in type 1 diabetes.
  Xinyu Xu, Yong Gu, Lingling Bian, Yun Shi, Yun Cai, Yang Chen, Heng Chen, Li Qian, Xiangmei Wu, Kuanfeng Xu, Roberto Mallone, Howard W. Davidson, Liping Yu, Jin-Xiong ...> ;Vaccine. 2016 Feb 3
• 20 citations
  Changes in Zinc Transporter 8 Autoantibodies Following Type 1 Diabetes Onset: The Type 1 Diabetes Genetics Consortium Autoantibody Workshop
  Janet M. Wenzlau, Lisa M. Frisch, John C. Hutton, Pamela R. Fain, Howard W. Davidson> ;Diabetes Care. 2015 Oct 1
• 53 citations
  Regulatory vs. inflammatory cytokine T-cell responses to mutated insulin peptides in healthy and type 1 diabetic subjects
  Maki Nakayama, Kristen McDaniel, Lisa Fitzgerald-Miller, Carol M. Kiekhaefer, Janet K. Snell-Bergeon, Howard W. Davidson, Marian Rewers, Liping Yu, Peter A. Gottlieb, ...> ;Proceedings of the National Academy of Sciences of the United States of America. 2015 Apr 7
• 19 citations
  Preexisting Insulin Autoantibodies Predict Efficacy of Otelixizumab in Preserving Residual β-Cell Function in Recent-Onset Type 1 Diabetes
  Simke Demeester, Bart Keymeulen, Leonard Kaufman, Annelien Van Dalem, Eric V. Balti, Ursule Van de Velde, Patrick Goubert, Katrijn Verhaeghen, Howard W. Davidson, Jane...> ;Diabetes Care. 2015 Jan 12
• 95 citations
  Autoreactive T cells specific for insulin B:11-23 recognize a low-affinity peptide register in human subjects with autoimmune diabetes.
  Junbao Yang, I-Ting Chow, Tomasz Sosinowski, Nadia Torres-Chinn, Carla J. Greenbaum, Eddie A. James, John W. Kappler, Howard W. Davidson, William W. Kwok> ;Proceedings of the National Academy of Sciences of the United States of America. 2014 Oct 14
• 96 citations
  Zinc transporter 8 (ZnT8) and β cell function.
  Howard W. Davidson, Janet M. Wenzlau, Richard M. O'Brien> ;Trends in Endocrinology and Metabolism. 2014 Aug 1
• 47 citations
  Monoclonal antibody blocking the recognition of an insulin peptide-MHC complex modulates type 1 diabetes.
  Li Zhang, Frances Crawford, Liping Yu, Aaron W. Michels, Maki Nakayama, Howard W. Davidson, John W. Kappler, George S. Eisenbarth> ;Proceedings of the National Academy of Sciences of the United States of America. 2014 Feb 18
• 3 citations
  Mapping I-A(g7) restricted epitopes in murine G6PC2.
  Tao Yang, Anita Hohenstein, Catherine E. Lee, John C. Hutton, Howard W. Davidson> ;Immunologic Research. 2013 Mar 1
• 35 citations
  Glycotoxin and Autoantibodies Are Additive Environmentally Determined Predictors of Type 1 Diabetes: A Twin and Population Study
  Huriya Beyan, Harriëtte Riese, Mohammed I. Hawa, G. Beretta, Howard W. Davidson, John C. Hutton, Huibert Burger, Michael Schlosser, Harold Snieder, Bernhard O. Boehm, ...> ;Diabetes. 2012 May 1
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