Howard P Safran MD

Clinical Trials

• Liposomal Doxorubicin in Treating Patients With Liver or Bile Duct Cancer Start of enrollment: 1998 Jan 01

  Unknown status

  Phase 2

• Gemcitabine and Monoclonal Antibody Therapy in Treating Patients With Metastatic Cancer of the Pancreas Start of enrollment: 1999 Mar 01

  Unknown status

  Phase 2

• A Trial of GW572016, Gemcitabine and Oxaliplatin for Metastatic Pancreaticobiliary Cancer Schema Start of enrollment: 2006 Jul 01

  Completed

  Phase 1

• Cetuximab, Paclitaxel, Carboplatin & Radiation for Esoph, Gastroesoph & Gastric Cancer Start of enrollment: 2004 Oct 01

  Completed

  Phase 2

• BrUOG-PA-209: Lapatinib and Gemcitabine for Metastatic Pancreaticobiliary Cancer Start of enrollment: 2007 Mar 01

  Terminated

  Phase 1

• Neoadjuvant Paclitaxel Poliglumex, Cisplatin and Radiation for Esophageal Cancer: A Phase II Trial (CTI#X64001) Start of enrollment: 2007 Aug 01

  Completed

  Phase 2

• Lenalidomide for Advanced Hepatocellular Cancer:A Phase II Trial Start of enrollment: 2009 Jan 01

  Completed

  Phase 2

• A Study of Dasatinib With Concurrent Chemoradiation for Stage III Non-Small Cell Lung Cancer (NSCLC) Start of enrollment: 2009 Mar 01

  Terminated

  Phase 1

• Gemcitabine Hydrochloride With or Without Erlotinib Hydrochloride Followed by the Same Chemotherapy Regimen With or Without Radiation Therapy and Capecitabine or Fluorouracil in Treating Patients With Pancreatic Cancer That Has Been Removed by Surgery Start of enrollment: 2010 Apr 05

  ACTIVE_NOT_RECRUITING

  PHASE3

• RAD001, Cisplatin and Concurrent Radiation for Locally Advanced, Inoperable Head and Neck Cancer Start of enrollment: 2009 Dec 01

  Terminated

  Phase 1

• Ofatumumab and Bortezomib for Patients With Low-grade B-cell Non-hodgkin Lymphoma That Relapse After Rituximab Start of enrollment: 2010 Jul 01

  Terminated

  Phase 2

• Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer Start of enrollment: 2011 Feb 14

  Completed

  Phase 3

• Ridaforolimus With Cetuximab: Adv Non-Small Cell Lung, Colorectal, Head & Neck Cancer Start of enrollment: 2010 Sep 01

  Terminated

  Phase 1

• Chemotherapy for Patients With Gastroesophageal Cancers Who Have Progressed After One Prior Chemo Regimen Start of enrollment: 2011 Jun 01

  Terminated

  Phase 2

• Cabazitaxel and Radiation For Patients With Prostate Cancer Start of enrollment: 2013 Jan 01

  Terminated

  Phase 2

• Low Dose Naltrexone for Metastatic Melanoma, Castrate Resistant Prostate Cancer and Renal Cancer Start of enrollment: 2012 Nov 01

  Terminated

  Phase 2

• Stereotactic Body Radiation for Consolidation After Standard Chemoradiation for Stage 3 Lung Cancer Start of enrollment: 2012 Apr 01

  Completed

  Not Applicable

• Adjuvant Aflibercept for Metastatic Colorectal Cancer Start of enrollment: 2012 Dec 01

  Terminated

  Phase 2

• A Phase I/II Evaluation of ADXS11-001, Mitomycin, 5-fluorouracil (5-FU) and IMRT for Anal Cancer Start of enrollment: 2013 Feb 01

  Terminated

  Phase 1, Phase 2

• Study of Infusion of Blood Cells (Lymphocytes) to Stimulate the Immune System to Fight Leukemia/Lymphoma Start of enrollment: 2013 Mar 01

  Terminated

  Phase 2

• A Dose Finding Study of Eribulin Mesylate and Cetuximab For Patients With Advanced Head and Neck and Colon Cancer Start of enrollment: 2012 May 01

  Completed

  Phase 1, Phase 2

• BrUOG 278: FOLFOX-A For Pancreatic Cancer A Brown University Oncology Research Group Study Start of enrollment: 2012 Nov 01

  Completed

  Phase 1

• Rectal Cancer Consortium Start of enrollment: 2013 Jul 01

  Completed

• BrUOG 263: Prostate Specific Membrane Antigen (PSMA) Glioblastoma Multiforme (GBM) Start of enrollment: 2013 May 01

  Completed

  Phase 2

• BrUOG 295: Adjuvant FOLFOX-A For Resected Pancreatic Cancer: A Phase II Brown University Oncology Research Group Trial Start of enrollment: 2014 Feb 01

  Completed

  Phase 2

• Neoadjuvant Gemcitabine and Fractionated, Weekly Cisplatin For Muscle Invasive Bladder Cancer and Patients Not Candidates For High Dose Cisplatin Start of enrollment: 2014 Jul 01

  Terminated

  Phase 2

• BrUOG 292: FOLFOX-A For Metastatic Pancreatic Cancer: A Phase II Brown University Oncology Research Group Trial Start of enrollment: 2014 Aug 01

  Completed

  Phase 2

• BGJ398 for Patients With Tumors With FGFR Genetic Alterations Start of enrollment: 2014 Jul 24

  Terminated

  Phase 2

• Ceritinib (LDK378) for Patients Whose Tumors Have Aberrations in ALK or ROS1 (SIGNATURE) Start of enrollment: 2014 Sep 17

  Terminated

  Phase 2

• LEE011 for Patients With CDK4/6 Pathway Activated Tumors (SIGNATURE) Start of enrollment: 2014 Aug 25

  Completed

  Phase 2

• Molecular Testing of Cancer by Integrated Genomic, Transcriptomic, and Proteomic Analysis Start of enrollment: 2013 May 01

  Unknown status

• A Study of Ramucirumab (LY3009806) Plus MEDI4736 in Participants With Advanced Gastrointestinal or Thoracic Malignancies Start of enrollment: 2016 Feb 19

  Completed

  Phase 1

• Improving Cancer Screening and Prevention During the COVID-19 Pandemic in Underserved Populations of Rhode Island Start of enrollment: 2020 Aug 28

  Recruiting

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