HristelinaS.IlievaMD

PubMed

• 3 citations
  Advances in molecular pathology, diagnosis, and treatment of amyotrophic lateral sclerosis.
  Hristelina Ilieva, Mithila Vullaganti, Justin Kwan> ;BMJ. 2023 Oct 27
• 6 citations
  Targeting TNFα produced by astrocytes expressing amyotrophic lateral sclerosis-linked mutant fused in sarcoma prevents neurodegeneration and motor dysfunction in mice.
  Brigid K Jensen, Kevin J McAvoy, Nicolette M Heinsinger, Angelo C Lepore, Hristelina Ilieva, Aaron R Haeusler, Davide Trotti, Piera Pasinelli> ;Glia. 2022 Jul 1
• 11 citations
  Increased synthesis of pro-inflammatory cytokines in C9ORF72 patients
  Gabriel Pinilla, Anupama Kumar, Mary Kay Floaters, Carlos A. Pardo, Jeffrey D. Rothstein, Hristelina Ilieva> ;Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 2021 Apr 30
• 3 citations
  Valproic acid and zonisamide induced hyperammonemic encephalopathy.
  Hristelina Ilieva, Joseph W. Newman, Ronald K. Fields, John E. Croom> ;Clinical Neurology and Neurosurgery. 2020 May 15
• 47 citations
  Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis.
  Shuo-Chien Ling, Somasish Ghosh Dastidar, Seiya Tokunaga, Wan Yun Ho, Kenneth Lim, Hristelina Ilieva, Philippe A. Parone, Sheue Houy Tyan, Tsemay M. Tse, Jer Cherng Ch...> ;Elife. 2019 Feb 12
• Motoneuron Disease: Clinical.
  Hristelina Ilieva, Nicholas J. Maragakis> ;Advances in Neurobiology. 2017 Jan 1
• 3 citations
  Motoneuron disease: Basic science
  Hristelina Ilieva, Nicholas J. Maragakis> ;Advances in Neurobiology. 2017 Jan 1
• 166 citations
  Mitochondria‐associated membrane collapse is a common pathomechanism in SIGMAR1‐ and SOD1‐linked ALS
  Seiji Watanabe, Hristelina Ilieva, Hiromi Tamada, Hanae Nomura, Okiru Komine, Fumito Endo, Shijie Jin, Pedro Mancias, Hiroshi Kiyama, Koji Yamanaka> ;EMBO Molecular Medicine. 2016 Dec 1
• 148 citations
  Therapeutic AAV9-mediated Suppression of Mutant SOD1 Slows Disease Progression and Extends Survival in Models of Inherited ALS
  Kevin D. Foust, Desirée L. Salazar, Shibi Likhite, Laura Ferraiuolo, Dara Ditsworth, Hristelina Ilieva, Kathrin Meyer, Leah Schmelzer, Lyndsey Braun, Don W. Cleveland,...> ;Molecular Therapy. 2013 Dec 1
• 232 citations
  Misfolded Mutant SOD1 Directly Inhibits VDAC1 Conductance in a Mouse Model of Inherited ALS
  Adrian Israelson, Nir Arbel, Sandrine Da Cruz, Hristelina Ilieva, Koji Yamanaka, Varda Shoshan-Barmatz, Don W. Cleveland> ;Neuron. 2010 Aug 26
• 782 citations
  Non–cell autonomous toxicity in neurodegenerative disorders: ALS and beyond
  Hristelina Ilieva, Magdalini Polymenidou, Don W. Cleveland> ;The Journal of Cell Biology. 2009 Dec 14
• 145 citations
  Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells
  Zhihui Zhong, Hristelina Ilieva, Lee Hallagan, Robert D. Bell, Itender Singh, Nicole Paquette, Meenakshisundaram Thiyagarajan, Rashid Deane, José A. Fernández, Steven ...> ;The Journal of Clinical Investigation. 2009 Nov 2
• 79 citations
  Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death
  Hristelina Ilieva, Koji Yamanaka, Shelle Malkmus, Osamu Kakinohana, Tony L. Yaksh, Martin Marsala, Don W. Cleveland> ;Proceedings of the National Academy of Sciences of the United States of America. 2008 Aug 26
• 155 citations
  Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALS.
  Yueming Chang, Qiongman Kong, Xiu Shan, Guilian Tian, Hristelina Ilieva, Don W. Cleveland, Jeffrey D. Rothstein, David R. Borchelt, Philip C. Wong, Chien Liang Glenn Lin> ;Plos One. 2008 Aug 6
• 56 citations
  Increased ER stress during motor neuron degeneration in a transgenic mouse model of amyotrophic lateral sclerosis.
  Tetsuya Nagata, Hristelina Ilieva, Tetsuro Murakami, Mito Shiote, Hisashi Narai, Yasuyuki Ohta, Takeshi Hayashi, Mikio Shoji, Koji Abe> ;Neurological Research. 2007 Dec 1
• 79 citations
  Therapeutic benefit of intrathecal injection of insulin-like growth factor-1 in a mouse model of Amyotrophic Lateral Sclerosis.
  Isao Nagano, Hristelina Ilieva, Mito Shiote, Tetsuro Murakami, Masataka Yokoyama, Mikio Shoji, Koji Abe> ;Journal of the Neurological Sciences. 2005 Aug 15
• 25 citations
  Reduction of a vascular endothelial growth factor receptor, fetal liver kinase-1, by antisense oligonucleotides induces motor neuron death in rat spinal cord exposed t...
  Mito Shiote, Isao Nagano, Hristelina Ilieva, Tetsuro Murakami, Hisashi Narai, Yasuyuki Ohta, Tetsuya Nagata, Mikio Shoji, Koji Abe> ;Neuroscience. 2005 Jan 1
• 18 citations
  Sustained induction of survival p-AKT and p-ERK signals after transient hypoxia in mice spinal cord with G93A mutant human SOD1 protein
  Hristelina Ilieva, Isao Nagano, Tetsuro Murakami, Mito Shiote, Mikio Shoji, Koji Abe> ;Journal of the Neurological Sciences. 2003 Nov 15
• 42 citations
  Hypoxic induction of vascular endothelial growth factor is selectively impaired in mice carrying the mutant SOD1 gene.
  Tetsuro Murakami, Hristelina Ilieva, Mito Shiote, Tetsuya Nagata, Isao Nagano, Mikio Shoji, Koji Abe> ;Brain Research. 2003 Nov 7
• 4 citations
  Age-related changes in peroxisomal membrane protein 70 and superoxide dismutase 1 in transgenic G93A mice
  Hristelina Ilieva, Isao Nagano, Tetsuro Murakami, Mito Shiote, Yasuhiro Manabe, Koji Abe> ;Neurological Research. 2003 Jun 1
• 3 citations
  Change in superoxide dismutase1 protein localization towards mitochondria: an immunohistochemical study in transgenic G93A mice
  Hristelina Ilieva, Isao Nagano, Tetsuro Murakami, Mito Shiote, Yasuhiro Manabe, Koji Abe> ;Neuroscience Letters. 2002 Oct 25
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