Hsiang-ChunChangMDPhD

PubMed

• 4 citations
  Iron drives anabolic metabolism through active histone demethylation and mTORC1.
  Jason S Shapiro, Hsiang-Chun Chang, Yuki Tatekoshi, Zibo Zhao, Zohra Sattar Waxali, Bong Jin Hong, Haimei Chen, Justin A Geier, Elizabeth T Bartom, Adam De Jesus, Farn...> ;Nature Cell Biology. 2023 Oct 1
• 1 citations
  SIRT2 inhibition protects against cardiac hypertrophy and ischemic injury.
  Xiaoyan Yang, Hsiang-Chun Chang, Yuki Tatekoshi, Amir Mahmoodzadeh, Maryam Balibegloo, Zeinab Najafi, Rongxue Wu, Chunlei Chen, Tatsuya Sato, Jason Shapiro, Hossein Ar...> ;Elife. 2023 Sep 20
• DNA Damage and Nuclear Morphological Changes in Cardiac Hypertrophy Are Mediated by SNRK Through Actin Depolymerization.
  Paulina J Stanczyk, Yuki Tatekoshi, Jason S Shapiro, Krithika Nayudu, Yihan Chen, Zachary Zilber, Matthew Schipma, Adam De Jesus, Amir Mahmoodzadeh, Ashley Akrami, Hsi...> ;Circulation. 2023 Nov 14
• DNA damage and nuclear morphological changes in cardiac hypertrophy are mediated by SNRK through actin depolymerization.
  Paulina Stanczyk, Yuki Tatekoshi, Jason S Shapiro, Krithika Nayudu, Yihan Chen, Zachary Zilber, Matthew Schipma, Adam De Jesus, Amir Mahmoodzadeh, Ashley Akrami, Hsian...> ;Biorxiv. 2023 Jul 14
• Optimized protocol for quantification of mitochondrial non-heme and heme iron content in mouse tissues and cultured cells.
  Tatsuya Sato, Hsiang-Chun Chang, Konrad T Sawicki, Hossein Ardehali> ;STAR Protocols. 2023 Mar 17
• 8 citations
  ZFP36L2 suppresses mTORc1 through a P53-dependent pathway to prevent peripartum cardiomyopathy in mice.
  Hidemichi Kouzu, Yuki Tatekoshi, Hsiang-Chun Chang, Jason S Shapiro, Warren A McGee, Adam De Jesus, Issam Ben-Sahra, Zoltan Arany, Jonathan Leor, Chunlei Chen, Perry J...> ;The Journal of Clinical Investigation. 2022 May 16
• 36 citations
  Hexokinase 1 cellular localization regulates the metabolic fate of glucose.
  De Jesus, A., Keyhani-Nejad, F., Pusec, C., Goodman, L., Geier, J., Stoolman, J., Stanczyk, P., Nguyen, T., Xu, K., Suresh, K., Chen, Y., Rodriguez, A., Shapiro, J., C...> ;Molecular Cell. 2022 Apr 7
• 24 citations
  Aging is associated with increased brain iron through cortex-derived hepcidin expression.
  Tatsuya Sato, Jason Solomon Shapiro, Hsiang-Chun Chang, Richard A Miller, Hossein Ardehali> ;Elife. 2022 Jan 11
• 7 citations
  Augmenter of liver regeneration regulates cellular iron homeostasis by modulating mitochondrial transport of ATP-binding cassette B8.
  Hsiang-Chun Chang, Jason S. Shapiro, Xinghang Jiang, Grant Senyei, Teruki Sato, Justin Geier, Konrad T Sawicki, Hossein Ardehali> ;Elife. 2021 Apr 9
• 10 citations
  Intravenous iron therapy in heart failure: a different perspective.
  Kambiz Ghafourian, Hsiang-Chun Chang, Hossein Ardehali> ;European Journal of Heart Failure. 2019 Jun 1
• 2 citations
  Metabolic Suppression of HIF-1α Contributes to Susceptibility of Ischemic Injury in Diabetic Hearts∗
  Adam De Jesus, Hsiang-Chun Chang, Hossein Ardehali> ;JACC. Basic to Translational Science. 2018 Aug 28
• 51 citations
  mRNA-binding protein tristetraprolin is essential for cardiac response to iron deficiency by regulating mitochondrial function
  Tatsuya Sato, Hsiang-Chun Chang, Marina Bayeva, Jason S. Shapiro, Lucía Ramos-Alonso, Hidemichi Kouzu, Xinghang Jiang, Ting Liu, Sumeyye Yar, Konrad T Sawicki, Chunlei...> ;Proceedings of the National Academy of Sciences of the United States of America. 2018 Jul 3
• 23 citations
  Hepatic tristetraprolin promotes insulin resistance through RNA destabilization of FGF21.
  Konrad T Sawicki, Hsiang-Chun Chang, Jason S. Shapiro, Marina Bayeva, Adam De Jesus, Brian N. Finck, Jason A. Wertheim, Perry J. Blackshear, Hossein Ardehali> ;JCI Insight. 2018 Jul 12
• 19 citations
  Snf1-related kinase improves cardiac mitochondrial efficiency and decreases mitochondrial uncoupling
  Amy K. Rines, Hsiang-Chun Chang, Rongxue Wu, Tatsuya Sato, Arineh Khechaduri, Hidemichi Kouzu, Jason S. Shapiro, Meng Shang, Michael A. Burke, Xinghang Jiang, Chunlei ...> ;Nature Communications. 2017 Jan 24
• 4 citations
  Iron and Sex Cross Paths in the Heart.
  Jason S. Shapiro, Hsiang-Chun Chang, Hossein Ardehali> ;Journal of the American Heart Association. 2017 Jan 23
• 28 citations
  Getting to the “Heart” of Cardiac Disease by Decreasing Mitochondrial Iron
  Hsiang-Chun Chang, Jason S. Shapiro, Hossein Ardehali> ;Circulation Research. 2016 Nov 11
• 4 citations
  The Good Neighbor: Coping With Insulin Resistance by Modulating Adipose Tissue Endothelial Cell Function.
  Sumeyye Yar, Hsiang-Chun Chang, Hossein Ardehali> ;Circulation Research. 2016 Mar 4
• 96 citations
  Reduction in mitochondrial iron alleviates cardiac damage during injury
  Hsiang-Chun Chang, Rongxue Wu, Meng Shang, Tatsuya Sato, Chunlei Chen, Jason S. Shapiro, Ting Liu, Anita Thakur, Konrad T Sawicki, Sathyamangla Vn Prasad, Hossein Arde...> ;EMBO Molecular Medicine. 2016 Mar 1
• 12 citations
  Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice.
  Yuzhi Jia, Hsiang-Chun Chang, Matthew J Schipma, Jing Liu, Varsha Shete, Ning Liu, Tatsuya Sato, Edward B Thorp, Philip M Barger, Yi-Jun Zhu, Navin Viswakarma, Yashpal...> ;Plos One. 2016 Jan 1
• 42 citations
  Increased Heme Levels in the Heart Lead to Exacerbated Ischemic Injury.
  Konrad T Sawicki, Meng Shang, Rongxue Wu, Hsiang-Chun Chang, Arineh Khechaduri, Tatsuya Sato, Christine Kamide, Ting Liu, Sathyamangla V. Naga Prasad, Hossein Ardehali> ;Journal of the American Heart Association. 2015 Aug 25
• 53 citations
  Role of Heme in Cardiovascular Physiology and Disease
  Konrad T Sawicki, Hsiang-Chun Chang, Hossein Ardehali> ;Journal of the American Heart Association. 2015 Jan 5
• 33 citations
  Short Communication: High Cellular Iron Levels Are Associated with Increased HIV Infection and Replication
  Hsiang-Chun Chang, Marina Bayeva, Babafemi Taiwo, Frank J. Palella, Thomas J. Hope, Hossein Ardehali> ;AIDS Research and Human Retroviruses. 2015 Mar 1
• 23 citations
  When less is more: novel mechanisms of iron conservation
  Marina Bayeva, Hsiang-Chun Chang, Rongxue Wu, Hossein Ardehali> ;Trends in Endocrinology and Metabolism. 2013 Nov 1
• 58 citations
  Heme levels are increased in human failing hearts.
  Arineh Khechaduri, Marina Bayeva, Hsiang-Chun Chang, Hossein Ardehali> ;Journal of the American College of Cardiology. 2013 May 7
• 128 citations
  mTOR Regulates Cellular Iron Homeostasis through Tristetraprolin
  Marina Bayeva, Arineh Khechaduri, Sergi Puig, Hsiang-Chun Chang, Sonika Patial, Perry J. Blackshear, Hossein Ardehali> ;Cell Metabolism. 2012 Nov 7
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