Hui-ZiChenMD

PubMed

• Manzamine A reduces androgen receptor transcription and synthesis by blocking E2F8-DNA interactions and effectively inhibits prostate tumor growth in mice.
  Dev Karan, Seema Dubey, Sumedha Gunewardena, Manohar Singh, Pengyuan Liu, Angelo Poletti, Yeun-Mun Choo, Mark T Hamann, Kenneth A Iczkowski, Hui-Zi Chen> ;Molecular Oncology. 2024 Apr 11
• 6 citations
  ALK fusions in the pan-cancer setting: another tumor-agnostic target?
  Aditya Shreenivas, Filip Janku, Mohamed A Gouda, Hui-Zi Chen, Ben George, Shumei Kato, Razelle Kurzrock> ;NPJ Precision Oncology. 2023 Sep 29
• 6 citations
  Mainstreaming germline genetic testing for patients with pancreatic cancer increases uptake.
  Mitchell L Ramsey, Jewel Tomlinson, Rachel Pearlman, Laith Abushahin, Amber Aeilts, Hui-Zi Chen, Yan Chen, Ashley Compton, Rifat Elkhatib, Levi Geiger, John Hays, Joan...> ;Familial Cancer. 2023 Jan 1
• 3 citations
  Disparate Use of Chemoradiation in Elderly Patients With Localized Anal Cancer.
  Eric D. Miller, Ansel P. Nalin, Dayssy Alexandra Diaz Pardo, Emily Huang, Alessandra Gasior, Pannaga Malalur, Hui-Zi Chen, Terence M. Williams, Jose G. Bazan> ;Journal of the National Comprehensive Cancer Network. 2021 Jun 10
• 7 citations
  Genomic and Transcriptomic Characterization of Relapsed SCLC Through Rapid Research Autopsy.
  Hui-Zi Chen, Russell Bonneville, Anoosha Paruchuri, Julie W. Reeser, Michele R. Wing, Eric Samorodnitsky, Melanie A. Krook, Amy M. Smith, Thuy Dao, Jharna Miya, Walter...> ;JTO Clinical and Research Reports. 2021 Apr 1
• 127 citations
  Fibroblast growth factor receptors in cancer: genetic alterations, diagnostics, therapeutic targets and mechanisms of resistance
  Melanie A. Krook, Julie W. Reeser, Gabrielle Ernst, Hannah Barker, Max Wilberding, Gary Li, Hui-Zi Chen, Sameek Roychowdhury> ;British Journal of Cancer. 2021 Mar 2
• 2 citations
  Characterization of Clonal Evolution in Microsatellite Unstable Metastatic Cancers through Multiregional Tumor Sequencing
  Russell Bonneville, Anoosha Paruchuri, Michele R. Wing, Melanie A. Krook, Julie W. Reeser, Hui-Zi Chen, Thuy Dao, Eric Samorodnitsky, Amy M. Smith, Lianbo Yu, Nicholas...> ;Molecular Cancer Research. 2021 Mar 1
• 2 citations
  Research Autopsy Demonstrates Polyclonal Acquired Resistance in a Patient With Metastatic GI Stromal Tumor
  Anoosha Paruchuri, Hui-Zi Chen, Russell Bonneville, Julie W. Reeser, Michele R. Wing, Melanie A. Krook, Eric Samorodnitsky, Jharna Miya, Thuy Dao, Amy Smith, Aharon G....> ;JCO Precision Oncology. 2020 Mar 3
• 72 citations
  Efficacy of FGFR Inhibitors and Combination Therapies for Acquired Resistance in FGFR2-Fusion Cholangiocarcinoma
  Melanie A. Krook, Alexandria M. Lenyo, Max Wilberding, Hannah Barker, Mikayla Dantuono, Kelly M. Bailey, Hui-Zi Chen, Julie W. Reeser, Michele R. Wing, Jharna Miya, Er...> ;Molecular Cancer Therapeutics. 2020 Mar 1
• 35 citations
  Detection of Microsatellite Instability Biomarkers via Next-Generation Sequencing.
  Russell Bonneville, Melanie A. Krook, Hui-Zi Chen, Amy Smith, Eric Samorodnitsky, Michele R. Wing, Julie W. Reeser, Sameek Roychowdhury> ;Methods in Molecular Biology. 2020 Jan 1
• 53 citations
  Tumor heterogeneity and acquired drug resistance in FGFR2-fusion-positive cholangiocarcinoma through rapid research autopsy.
  Melanie A. Krook, Russell Bonneville, Hui-Zi Chen, Julie W. Reeser, Michele R. Wing, Dorrelyn M. Martin, Amy M. Smith, Thuy Dao, Eric Samorodnitsky, Anoosha Paruchuri,...> ;Cold Spring Harbor Molecular Case Studies. 2019 Aug 1
• 5 citations
  Characterization of a KLK2-FGFR2 fusion gene in two cases of metastatic prostate cancer.
  Melanie A. Krook, Hannah Barker, Hui-Zi Chen, Julie W. Reeser, Michele R. Wing, Dorrelyn Martin, Amy M. Smith, Thuy Dao, Russell Bonneville, Eric Samorodnitsky, Jharna...> ;Prostate Cancer and Prostatic Diseases. 2019 May 1
• 18 citations
  Implementing precision cancer medicine in the genomic era.
  Hui-Zi Chen, Russell Bonneville, Sameek Roychowdhury> ;Seminars in Cancer Biology. 2019 Apr 1
• 6 citations
  Genomic characterization of metastatic ultra-hypermutated interdigitating dendritic cell sarcoma through rapid research autopsy
  Hui-Zi Chen, Russell Bonneville, Lianbo Yu, Michele R. Wing, Julie W. Reeser, Melanie A. Krook, Jharna Miya, Eric Samorodnitsky, Amy Smith, Dorrelyn Martin, Thuy Dao, ...> ;Oncotarget. 2019 Jan 8
• 10 citations
  Rapid Research Autopsy: Piecing the Puzzle of Tumor Heterogeneity.
  Melanie A. Krook, Hui-Zi Chen, Russell Bonneville, Patricia Allenby, Sameek Roychowdhury> ;Trends in Cancer. 2019 Jan 1
• 13 citations
  Metastatic Calcinosis Cutis Associated With a Selective FGFR Inhibitor.
  David R. Carr, Llana Pootrakul, Hui-Zi Chen, Catherine Chung> ;JAMA Dermatology. 2019 Jan 1
• 805 citations
  Landscape of Microsatellite Instability Across 39 Cancer Types.
  Russell Bonneville, Melanie A. Krook, Esko A. Kautto, Jharna Miya, Michele R. Wing, Hui-Zi Chen, Julie W. Reeser, Lianbo Yu, Sameek Roychowdhury> ;JCO Precision Oncology. 2017 Oct 3
• 3 citations
  Tumor spread through air space (STAS) is an important predictor of clinical outcome in stage IA lung adenocarcinoma.
  Hui-Zi Chen, Erin M. Bertino, Kai He> ;Journal of Thoracic Disease. 2017 Aug 1
• 63 citations
  E2f8 mediates tumor suppression in postnatal liver development
  Lindsey N. Kent, Jessica B. Rakijas, Shusil K. Pandit, Bart Westendorp, Hui-Zi Chen, Justin T. Huntington, Xing Tang, Sooin Bae, Arunima Srivastava, Shantibhusan Senap...> ;The Journal of Clinical Investigation. 2016 Aug 1
• 113 citations
  Canonical and Atypical E2Fs Regulate the Mammalian Endocycle
  Hui-Zi Chen, Madhu M. Ouseph, Jing Li, Thierry Pécot, Veda Chokshi, Lindsey N. Kent, Sooin Bae, Morgan Byrne, Camille L. Duran, Grant Comstock, Prashant Trikha, Markus...> ;Nature Cell Biology. 2012 Nov 1
• 70 citations
  Atypical E2F Repressors and Activators Coordinate Placental Development
  Madhu M. Ouseph, Jing Li, Hui-Zi Chen, Thierry Pécot, Pamela L. Wenzel, John C. Thompson, Grant Comstock, Veda Chokshi, Morgan Byrne, Braxton Forde, Jean Leon Chong, K...> ;Developmental Cell. 2012 Apr 17
• 53 citations
  Cell proliferation in the absence of E2F1-3.
  Pamela L. Wenzel, Jean Leon Chong, M. Teresa Sáenz-Robles, Antoney Ferrey, John P. Hagan, Yorman M. Gomez, Ravi Rajmohan, Nidhi Sharma, Hui-Zi Chen, James M. Pipas, Mi...> ;Developmental Biology. 2011 Mar 1
• 56 citations
  Allele-specific tumor spectrum in pten knockin mice.
  Hui Wang, Matt Karikomi, Shan Naidu, Ravi Rajmohan, Enrico Caserta, Hui-Zi Chen, Maysoon Rawahneh, Julie Moffitt, Julie A. Stephens, Soledad Fernandez, Michael Weinste...> ;Proceedings of the National Academy of Sciences of the United States of America. 2010 Mar 16
• 60 citations
  E2F3 is a mediator of DNA damage-induced apoptosis.
  Luis A. Martinez, Elzbieta Goluszko, Hui-Zi Chen, Gustavo Leone, Sean M. Post, Guillermina Lozano, Zhenping Chen, Anne Chauchereau> ;Molecular and Cellular Biology. 2010 Jan 15
• 188 citations
  E2f1-3 switch from activators in progenitor cells to repressors in differentiating cells.
  Jean Leon Chong, Pamela L. Wenzel, M. Teresa Sáenz-Robles, Vivek Nair, Antoney Ferrey, John P. Hagan, Yorman M. Gomez, Nidhi Sharma, Hui-Zi Chen, Madhu M. Ouseph, Shu ...> ;Nature. 2009 Dec 17
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