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35 Park StreetSmilow Cancer Hospital at Yale-New HavenNew Haven, CT 06511
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Summary
- Ian Krop, MD, PhD is the Chief Clinical Research Officer and Associate Cancer Center Director for Clinical Research at the Yale Cancer Center. He also serves as the Chief Scientific Officer for the Translational Breast Cancer Research Consortium (TBCRC).
Dr. Krop received his undergraduate, medical and PhD degrees from Johns Hopkins University. He subsequently completed his residency in Internal Medicine at Johns Hopkins Hospital, and fellowship in hematology and medical oncology at Dana-Farber.
Dr. Krop is a translational investigator focused on the development of novel molecularly targeted therapies and immunotherapies for breast cancer, and elucidating the mechanisms of resistance to these treatments. The majority of his effort is concentrated in the area of HER2+ breast cancer. He was a leader in the development of the antibody-drug conjugates trastuzumab emtansine (T-DM1) and trastuzumab deruxtecan
Education & Training
- Johns Hopkins University School of MedicinePhD, 1996
- Mass General Brigham/Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer InstituteFellowship, Hematology and Medical Oncology, 1999 - 2002
- Johns Hopkins University School of MedicineResidency, 1996 - 1999
- Johns Hopkins University School of MedicineClass of 1996
Certifications & Licensure
- FL State Medical License 2023 - Present
- CT State Medical License 2022 - 2026
- MA State Medical License 2002 - 2023
- American Board of Internal Medicine Medical Oncology
Publications & Presentations
PubMed
- Detection of heterogeneous resistance mechanisms to tyrosine kinase inhibitors from cell-free DNA.Heather A Parsons, Conor Messer, Katheryn Santos, Jakob Weiss, David Merrell
Cell Genomics. 2025-09-09 - Outcomes of subsequent treatment regimens after trastuzumab deruxtecan in patients with metastatic breast cancer.Paolo Tarantino, Do Lee, Julia Foldi, Pamela R Soulos, Cary P Gross
Journal of the National Cancer Institute. 2025-08-14 - Predicting ovarian function loss after chemotherapy and anti-HER2 therapy in young breast cancer patients.Matteo Lambertini, Deirdre Allegranza, Ruediger P Laubender, Nadia Harbeck, Sandra M Swain
Journal of the National Cancer Institute. 2025-08-12
Press Mentions
- Researchers Aim to Adapt Metastatic Breast Cancer Therapy as Tumors ChangeJuly 2nd, 2025
- Early Breast Cancer Highlights from ASCO 2025June 24th, 2025
- Beverly Levy Walk and Block PartyMay 6th, 2025
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