IanJ.SarembockMDMB,ChB

Cardiology • Cincinnati, OH

Adult Congenital Heart Disease, Interventional Cardiology, Cardiac Critical Care

Ohio Heart & Vascular Center

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Office
Retired
Montgomery, OHIO
Cincinnati, OH 45237
Phone+1 513-206-1167
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Education & Training

Yale-New Haven Medical CenterFellowship, Cardiovascular Disease, 1986 - 1988
University of Cape Town Faculty of MedicineClass of 1975

Certifications & Licensure

OH State Medical License 2007 - 2024
VA State Medical License 1988 - 2008
TN State Medical License 2002 - 2003

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2013
Fellow (FACC) American College of Cardiology
Whos Who in Medicine and Healthcare Marquis Whos Who

Clinical Trials

IK-5001 for the Prevention of Remodeling of the Ventricle and Congestive Heart Failure After Acute Myocardial Infarction Start of enrollment: 2012 Apr 01
Completed
Not Applicable
Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation (The COAPT Trial) and COAPT CAS Start of enrollment: 2012 Aug 01
Active, not recruiting
Not Applicable

Publications & Presentations

PubMed

43 citations
Five-Year Follow-up after Transcatheter Repair of Secondary Mitral Regurgitation.
Gregg W Stone, William T Abraham, JoAnn Lindenfeld, Saibal Kar, Paul A Grayburn, D Scott Lim, Jacob M Mishell, Brian Whisenant, Michael Rinaldi, Samir R Kapadia, Vivek...> ;The New England Journal of Medicine. 2023 Jun 1
14 citations
Sex-Specific Outcomes of Transcatheter Mitral-Valve Repair and Medical Therapy for Mitral Regurgitation in Heart Failure.
Ioanna Kosmidou, JoAnn Lindenfeld, William T. Abraham, Michael Rinaldi, Samir R. Kapadia, Vivek Rajagopal, Ian J. Sarembock, Andreas Brieke, Prakriti Gaba, Jason H. Ro...> ;JACC. Heart Failure. 2021 Sep 1
95 citations
3-Year Outcomes of Transcatheter Mitral Valve Repair in Patients With Heart Failure
Michael J. Mack, JoAnn Lindenfeld, William T. Abraham, Saibal Kar, D. Scott Lim, Jacob M. Mishell, Brian Whisenant, Paul A. Grayburn, Michael Rinaldi, Samir R. Kapadia...> ;Journal of the American College of Cardiology. 2021 Mar 2
11 citations
Outcomes of transcatheter mitral valve repair for secondary mitral regurgitation by severity of left ventricular dysfunction
Stamatios Lerakis, Annapoorna Kini, Federico M. Asch, Saibal Kar, D. Scott Lim, Jacob M. Mishell, Brian Whisenant, Paul A. Grayburn, Neil J. Weissman, Michael Rinaldi,...> ;Eurointervention. 2021 Jul 20
4 citations
Transcatheter Aortic Valve Replacement and Left Ventricular Geometry: Survival and Gender Differences
Vien T. Truong, Wojciech Mazur, John Broderick, Gregory F. Egnaczyk, Dean J. Kereiakes, Ian J. Sarembock, Joseph K. Choo, Satya Shreenivas, Sherif F. Nagueh, Cheryl Ba...> ;Journal of the American Society of Echocardiography. 2020 Aug 20
2 citations
TAVR During the COVID-19 Pandemic: The ACC/SCAI Consensus Statement.
Satya Shreenivas, Joseph K. Choo, Geoffrey A. Answini, Ian J. Sarembock, Jeffrey Griffin, J. Michael Smith, Dean J. Kereiakes> ;JACC. Cardiovascular Interventions. 2020 Jul 13
37 citations
Clinical Outcomes Following Implantation of Thin-Strut, Bioabsorbable Polymer-Coated, Everolimus-Eluting SYNERGY Stents
Dean J. Kereiakes, Stephan Windecker, R. Lee Jobe, Shamir R. Mehta, Ian J. Sarembock, Robert L. Feldman, Bernardo Stein, Christophe Dubois, Timothy Grady, Shigeru Sait...> ;Circulation. Cardiovascular Interventions. 2019 Aug 27
1 citations
Impact of High Baseline Left Ventricular Filling Pressure on Transcatheter Aortic Valve Replacement Outcomes in Patients with Significant Mitral Annular Calcification.
Vien T. Truong, Wojciech Mazur, Cassady Palmer, Gregory F. Egnaczyk, Dean J. Kereiakes, Ian J. Sarembock, Joseph K. Choo, Satya Shreenivas, Sherif F. Nagueh, Chung, E.> ;Journal of the American Society of Echocardiography. 2019 Sep 1
3 citations
Transcatheter aortic valve replacement and cardiac conduction
Satya Shreenivas, Edward J. Schloss, Joseph K. Choo, Ian J. Sarembock, Scott Lilly, Dean J. Kereiakes> ;Expert Review of Cardiovascular Therapy. 2019 Apr 19
427 citations
Transcatheter Mitral-Valve Repair in Patients with Heart Failure.
Gregg W Stone, JoAnn Lindenfeld, William T Abraham, Saibal Kar, D Scott Lim, Jacob M Mishell, Brian Whisenant, Paul A Grayburn, Michael Rinaldi, Samir R Kapadia, Vivek...> ;The New England Journal of Medicine. 2018 Dec 13
29 citations
ACIST-FFR Study (Assessment of Catheter-Based Interrogation and Standard Techniques for Fractional Flow Reserve Measurement).
William F. Fearon, Jeffrey W. Chambers, Arnold H. Seto, Ian J. Sarembock, Ganesh Raveendran, Charlotte Sakarovitch, Lingyao Yang, Manisha Desai, Allen Jeremias, Matthe...> ;Circulation. Cardiovascular Interventions. 2017 Dec 1
3 citations
Low-Volume Contrast CT Angiography Via Pulmonary Artery Injection for Measurement of Aortic Annulus in Patients Undergoing Transcatheter Aortic Valve Replacement.
Vien T. Truong, Joseph K. Choo, Luke McCoy, Adam Mussman, Stephanie Ambach, Dean J. Kereiakes, Ian J. Sarembock, Wojciech Mazur> ;The Journal of Invasive Cardiology. 2017 May 1
46 citations
SYNTAX Score and Long-Term Outcomes: The BARI-2D Trial
Fumiaki Ikeno, Maria M. Brooks, Kaori Nakagawa, Min Kyu Kim, Hideaki Kaneda, Yoshiaki Mitsutake, Helen Vlachos, Leonard Schwartz, Robert L. Frye, Sheryl F. Kelsey, Kat...> ;Journal of the American College of Cardiology. 2017 Jan 31
183 citations
Efficacy and Safety of a Novel Bioabsorbable Polymer-Coated, Everolimus-Eluting Coronary Stent The EVOLVE II Randomized Trial
Dean J. Kereiakes, Ian T Meredith, Stephan Windecker, R. Lee Jobe, Shamir R. Mehta, Ian J. Sarembock, Robert L. Feldman, Bernardo Stein, Christophe Dubois, Timothy Gra...> ;Circulation. Cardiovascular Interventions. 2015 Apr 1
8 citations
Sex, Prescribing Practices and Guideline Recommended, Blood Pressure, and LDL Cholesterol Targets at Baseline in the BARI 2D Trial
Michelle F. Magee, Jacqueline E. Tamis-Holland, Jiang Lu, Vera Bittner, Maria M. Brooks, Neuza Lopes, Alice K. Jacobs, Katherine M. Detre, Sheryl F. Kelsey, Trevor J. ...> ;International Journal of Endocrinology. 2015 Mar 19
19 citations
Use of the REG1 anticoagulation system in patients with acute coronary syndromes undergoing percutaneous coronary intervention: results from the phase II RADAR-PCI study.
Thomas J. Povsic, John P. Vavalle, John H. Alexander, Laura H. Aberle, Steven L. Zelenkofske, Richard C. Becker, Christopher E. Buller, Mauricio G. Cohen, Jan H. Corne...> ;Eurointervention. 2014 Aug 1
2 citations
Risk Stratification and Timing of Revascularization: Which Patients Benefit from Early Versus Later Revascularization?
Ian J. Sarembock, Dean J. Kereiakes> ;Current Cardiology Reports. 2012 May 13
33 citations
Accelerated Atherosclerosis in Apoe−/− Mice Heterozygous for the Insulin Receptor and the Insulin Receptor Substrate-1
Elena V. Galkina, Matthew J. Butcher, Susanna R. Keller, Matthew Goff, Anthony C. Bruce, Hong Pei, Ian J. Sarembock, John M. Sanders, Melissa H. Nagelin, Suseela Srini...> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2012 Feb 1
7 citations
From systemic shotgun to site-specific nanoparticle-targeted delivery: a new paradigm for drug delivery.
Ian J. Sarembock> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2008 Nov 1
88 citations
CD40 Ligand Promotes Mac-1 Expression, Leukocyte Recruitment, and Neointima Formation after Vascular Injury
Guohong Li, John M. Sanders, Melissa Bevard, Zhi Qi Sun, James W. Chumley, Elena V. Galkina, Klaus Ley, Ian J. Sarembock> ;The American Journal of Pathology. 2008 Apr 1
83 citations
The Truth and Consequences of the COURAGE Trial
Dean J. Kereiakes, Paul S. Teirstein, Ian J. Sarembock, David R. Holmes, Mitchell W. Krucoff, William W. O'Neill, Ron Waksman, David O. Williams, Jeffrey J. Popma, Mau...> ;Journal of the American College of Cardiology. 2007 Oct 16
268 citations
Molecular Imaging of Inflammation in Atherosclerosis With Targeted Ultrasound Detection of Vascular Cell Adhesion Molecule-1
Beat A. Kaufmann, John M. Sanders, Christopher K. Davis, Aris Xie, Patrick Aldred, Ian J. Sarembock, Jonathan R. Lindner> ;Circulation. 2007 Jul 17
189 citations
Expression of Heme Oxygenase-1 in Human Vascular Cells Is Regulated by Peroxisome Proliferator-Activated Receptors
Gerhard Krönke, Alexandra Kadl, Elena Ikonomu, Stefan Bluml, Alexander Furnkranz, Ian J. Sarembock, Valery N. Bochkov, Markus Exner, Bernd R. Binder, Norbert Leitinger> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2007 Jun 1
99 citations
Comparison between angiography and fractional flow reserve versus single-photon emission computed tomographic myocardial perfusion imaging for determining lesion signi...
Michael Ragosta, Andrew H. Bishop, Lewis C. Lipson, Denny D. Watson, Lawrence W. Gimple, Ian J. Sarembock, Eric R. Powers> ;The American Journal of Cardiology. 2007 Apr 1
111 citations
Matrix-specific p21-activated kinase activation regulates vascular permeability in atherogenesis
A. Wayne Orr, Rebecca A. Stockton, Michael B. Simmers, John M. Sanders, Ian J. Sarembock, Brett R. Blackman, Martin A. Schwartz> ;The Journal of Cell Biology. 2007 Feb 26
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Journal Articles

Transcatheter Mitral-Valve Repair in Patients with Heart Failure
JoAnn Lindenfeld, Saibal Kar, Michael J Mack, Samir R Kapadia, Gregg W Stone, Ian J Sarembock, William T Abraham, Andreas Brieke, David J Cohen, Steven O Marx, Brian W..., The New England Journal of Medicine

Grant Support

Selectins Role In Vascular Injury In Gene-TargetedNational Heart, Lung, And Blood Institute2003–2004
Selectins Role In Vascular Injury In Gene-Targeted MiceNational Heart, Lung, And Blood Institute2001–2002
Novel Adenosine A2A Agonists In Vascular ProtectionNational Heart, Lung, And Blood Institute2000
Effect Of Thrombin Inhibition By Hirudin On AngioplastyNational Heart, Lung, And Blood Institute1991–1993

Professional Memberships

American College of Cardiology - ACC
Member