IanWelsbyMD

Cardiothoracic Anesthesiology, Critical Care Medicine

Professor of Anesthesiology with Tenure, Professor of Medicine (Division of Hematology), Duke University School of Medicine

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Office
2301 Erwin Rd
Durham, NC 27705
Phone+1 919-684-8111

Fax+1 919-620-4921
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Education & Training

University of London Faculty of MedicineClass of 1990

Certifications & Licensure

NC State Medical License 2000 - 2024

Clinical Trials

Open Label Use Of RiaStap During Aortic Reconstruction Start of enrollment: 2010 Dec 01
Completed
Phase 4
LIPS-A: Lung Injury Prevention Study With Aspirin Start of enrollment: 2012 Jan 01
Completed
Phase 2
High Yield Intraoperative, Autologous Platelet Apheresis Start of enrollment: 2013 Jan 01
Completed
Not Applicable
Rejuvesol® Washed RBC in Sickle Cell Patients Requiring Frequent Transfusions Start of enrollment: 2016 Dec 01
Completed
Phase 4
Rejuvenated RBC and VO2 Max in Healthy Subjects Start of enrollment: 2017 Sep 29
Terminated
Phase 4
Evaluation of the Clinical Performance of the Quantra System With the Quantra Surgical Cartridge Start of enrollment: 2017 May 23
Completed
Voxelotor for Improving Oxygen Saturation in Adults Start of enrollment: 2022 May 03
Terminated
Phase 2
Roles: Principal Investigator, Contact
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Publications & Presentations

PubMed

Oxidative Stress and Cerebral Vascular Tone: The Role of Reactive Oxygen and Nitrogen Species.
Michele Salvagno, Elda Diletta Sterchele, Mario Zaccarelli, Simona Mrakic-Sposta, Ian James Welsby, Costantino Balestra, Fabio Silvio Taccone> ;International Journal of Molecular Sciences. 2024 Mar 5
Thoracic Epidural Analgesia for Hepatic Arterial Infusion Pump Implantation.
Maher, J., Record, S., Ganesh, A., Welsby, I., Lidsky, M.> ;Anesthesia and Analgesia. 2024 Mar 1
Evaluation of the efficacy and safety of amustaline/glutathione pathogen-reduced RBCs in complex cardiac surgery: the Red Cell Pathogen Inactivation (ReCePI) study-pro...
McNeil, J. S., Edward L Snyder, Michael E Sekela, Ian J Welsby, Yoshiya Toyoda, Mohamed Alsammak, Neel R Sodha, Thomas M Beaver, J Peter R Pelletier, James D Gorham, J...> ;Trials. 2023 Dec 11
Anemia after cardiac surgery: what is its link to outcomes?
Sharon L McCartney, Nadia B Hensley, Ian Welsby> ;Canadian Journal of Anaesthesia = Journal Canadien D'anesthesie. 2024 Mar 1
Characterization of an andexanet alfa administration protocol guided by drug-specific quantitative anti-Xa assays.
Holly T Lanham, Wassamon Viriyakitja, Mark Vestal, Ian Welsby, Bridgette Kram> ;Journal of Thrombosis and Thrombolysis. 2024 Feb 1
Voxelotor as a Treatment of Persistent Hypoxia in the ICU.
Omar Al-Qudsi, John M Reynolds, John C Haney, Ian J Welsby> ;Chest. 2023 Jul 1
1 citations
Clinical Relevance of Preclinical and Clinical Studies of Four-Factor Prothrombin Complex Concentrate for Treatment of Bleeding Related to Direct Oral Anticoagulants.
Ravi Sarode, Ian J Welsby, Maureane Hoffman> ;Annals of Emergency Medicine. 2023 Sep 1
1 citations
Development of New Donor-Specific and Human Leukocyte Antigen Antibodies After Transfusion in Adult Lung Transplantation.
Alexander Stoker, Anne Hicks, Mary Cooter Wright, Azfar Ali, Jacob Klapper, Jessica Poisson, Lorenzo Zaffiri, Dongfeng Chen, Matthew Hartwig, Kamrouz Ghadimi, Ian Wels...> ;Journal of Cardiothoracic and Vascular Anesthesia. 2023 Sep 1
Targeting Chemoprophylaxis in Venous Thromboembolism Using Biomarker Guidance.
Michael H Cutrone, Ian J Welsby, Kamrouz Ghadimi> ;JAMA Surgery. 2023 Feb 1
20 citations
Prothrombin Complex Concentrate vs Plasma for Post-Cardiopulmonary Bypass Coagulopathy and Bleeding: A Randomized Clinical Trial.
Mark M Smith, Darrell R Schroeder, James A Nelson, William J Mauermann, Ian J Welsby, Alberto Pochettino, Beth L Montonye, Chalailak Assawakawintip, Gregory A Nuttall> ;JAMA Surgery. 2022 Sep 1
2 citations
Optimizing management of sickle cell disease in patients undergoing surgery.
Charity I Oyedeji, Ian J Welsby> ;Hematology. American Society of Hematology. Education Program. 2021 Dec 10
A Step toward Combined Platelet and Erythrocyte Recovery.
David Faraoni, Ian J. Welsby> ;Anesthesiology. 2021 Aug 1
4 citations
Blood product transfusion and lung transplant outcomes: A systematic review.
Jacob A. Klapper, Anne C Hicks, Leila Ledbetter, Jessica Poisson, Matthew G. Hartwig, Nazish Hashmi, Ian J. Welsby, Brandi A. Bottiger> ;Clinical Transplantation. 2021 Jun 27
Heated Humidified Breathing Circuit Rewarming in Hypothermic Patients Post-Cardiopulmonary Bypass-Pilot Study.
Benjamin Brockbank, Mary Cooter Wright, Jhaymie L Cappiello, Brittany A. Zwischenberger, Ian J. Welsby, Jerrold H. Levy, Negmeldeen F. Mamoun> ;Journal of Cardiothoracic and Vascular Anesthesia. 2021 Jun 20
19 citations
Andexanet alfa and four-factor prothrombin complex concentrate for reversal of apixaban and rivaroxaban in patients diagnosed with intracranial hemorrhage
Mark L Vestal, Kimberly L. Hodulik, Jennifer Mando-Vandrick, Michael L. James, Thomas L. Ortel, Matthew Fuller, Maria Notini, Mark D Friedland, Ian J. Welsby> ;Journal of Thrombosis and Thrombolysis. 2021 Jun 8
21 citations
Fatty acid desaturase activity in mature red blood cells and implications for blood storage quality.
Tiffany Thomas, Francesca Cendali, Xiaoyun Fu, Fabia Gamboni, Evan J Morrison, Jonathan Beirne, Travis Nemkov, Marianna H. Antonelou, Anastasios G. Kriebardis, Ian J. ...> ;Transfusion. 2021 Apr 26
3 citations
Modulation of red blood cell oxygen affinity with a novel allosteric modifier of hemoglobin is additive to the Bohr effect.
Brooke A Evans, Andrea Ansari, Reed W. Kamyszek, Michele Salvagno, John Welsby, Matthew Fuller, Ian J. Welsby> ;Blood Cells, Molecules & Diseases. 2021 Mar 1
4 citations
Bedside Allogeneic Erythrocyte Washing with a Cell Saver to Remove Cytokines, Chemokines, and Cell-derived Microvesicles.
Ian J. Welsby, Philip J. Norris, William J. Mauermann, Mihai V. Podgoreanu, Chelsea M. Conn, Laurie Meade, Tamara Cannon, Sheila M. Keating, Christopher C. Silliman, M...> ;Anesthesiology. 2021 Mar 1
6 citations
Management of Perioperative Iron Deficiency in Cardiac Surgery: A Modified RAND Delphi Study.
Howard L. Corwin, Aryeh Shander, Bruce Speiss, Manuel Muñoz, David Faraoni, Domenico Calcaterra, Ian J. Welsby, Sherri Ozawa, Adam Arnofsky, Richard S. Goldweit, Pierr...> ;The Annals of Thoracic Surgery. 2020 Dec 17
8 citations
Conventional Ultrafiltration During Elective Cardiac Surgery and Postoperative Acute Kidney Injury.
Michael W. Manning, Yi-Ju Li, Dean Linder, John C. Haney, Yi-Hung Wu, Mihai V. Podgoreanu, Madhav Swaminathan, Jacob N. Schroder, Carmelo A. Milano, Ian J. Welsby, Mar...> ;Journal of Cardiothoracic and Vascular Anesthesia. 2021 May 1
2 citations
Global sources of cryoprecipitate demonstrate variability in coagulant factor levels and functional hemostasis.
Brooke A Evans, Reed W. Kamyszek, Mark Piegore, Keaton Stoner, Matthew Fuller, Ian J. Welsby, Micah J. Mooberry> ;Blood Coagulation & Fibrinolysis. 2021 Mar 1
27 citations
COVID-19 associated coagulopathy: Thrombosis, hemorrhage and mortality rates with an escalated-dose thromboprophylaxis strategy.
Molly M Daughety, Andrew Morgan, Erin Frost, Chester Kao, Joyce K. Hwang, Rachel Tobin, Bhavik N. Patel, Matthew Fuller, Ian J. Welsby, Thomas L. Ortel> ;Thrombosis Research. 2020 Oct 15
13 citations
Clinical outcomes of cardiac surgery patients undergoing therapeutic plasma exchange for heparin-induced thrombocytopenia.
Ingrid Moreno-Duarte, Mary Cooter, Oluwatoyosi A. Onwuemene, Kamrouz Ghadimi, Ian J. Welsby> ;Vox Sanguinis. 2021 Feb 1
3 citations
Activated Coagulation Time and Hepcon Protamine Titration Device to Manage Unfractionated Heparin During Cardiopulmonary Bypass in a Hemophilia A Patient on Emicizumab
James Isaacs, Ian J. Welsby, Jacob N. Schroder, Oluwatoyosi A. Onwuemene> ;Journal of Cardiothoracic and Vascular Anesthesia. 2021 Nov 1
8 citations
The effect of pathogen inactivation on cryoprecipitate: a functional and quantitative evaluation.
Reed W. Kamyszek, Matthew W. Foster, Brooke A Evans, Keaton Stoner, Jessica Poisson, Amudan J Srinivasan, J. Will Thompson, M. Arthur Moseley, Micah J. Mooberry, Ian J...> ;Blood Transfusion = Trasfusione Del Sangue. 2020 Aug 6
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Journal Articles

Effects of Red Blood Cell (RBC) Transfusion on Sickle Cell Disease Recipient Plasma and RBC Metabolism
Nirmish Shah, Ian Welsby, Reed Kamyszek, Andrea Ansari, Transfusion