Ik-KyungJangMD

Cardiology • Boston, MA

Interventional Cardiology

Professor of Medicine, Harvard Medical School Michael and Kathryn Park Endowed Chair in Cardiology

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Office
55 Fruit St
Grb 843
Boston, MA 02114
Phone+1 617-726-9226

Fax+1 617-726-7419
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Education & Training

Massachusetts General HospitalResidency, Internal Medicine, 1988 - 1989
Kyung Hee University College of MedicineClass of 1980

Certifications & Licensure

MA State Medical License 1991 - 2024
American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

Fellow (FACC) American College of Cardiology

Clinical Trials

Comparison of DSCT With IB-IVUS and Angiography in the Assessment of Coronary Artery Disease Start of enrollment: 2008 Jan 01
Terminated
Not Applicable
The Massachusetts General Hospital Optical Coherence Tomography Registry Start of enrollment: 2010 Aug 01
Completed
Significance of Antibodies to Heparin/Platelet Factor 4 Complex in Vein Graft Patency and Potential Role of Argatroban for Prevention of Vein Graft Occlusion Start of enrollment: 2010 Nov 01
Terminated
Phase 4
Evaluation of a Combined Near Infrared Spectroscopy (NIRS) and Intravascular Ultrasound (IVUS) Catheter for Detection of Lipid Rich Plaque Start of enrollment: 2012 Jan 01
Terminated
Phase 4
Combined Use of Angiography, Optical Coherence Tomography and Intravascular Ultrasound in Evaluation of Pulmonary Vascular Structure and Function in Patients With Pulmonary Arterial Hypertension Treated With Oral Bosentan Start of enrollment: 2012 May 01
Withdrawn
Phase 4
Comparison of Ticagrelor Versus Clopidogrel on Residual Thrombus Burden During PCI: an OCT Study Start of enrollment: 2013 May 01
Withdrawn
Phase 4
Effect of Pretreatment With Ticagrelor on Residual Thrombus After PCI in Patients Presenting With ACS in Comparison With Delayed Treatment at the Time of PCI: an OCT Study Start of enrollment: 2014 Feb 01
Withdrawn
Phase 4
Identification of Predictors for Coronary Plaque Erosion in Patients With Acute Coronary Syndrome Start of enrollment: 2017 Dec 01
Recruiting
Massachusetts General Hospital and Tsuchiura Kyodo General Hospital Coronary Imaging Collaboration Start of enrollment: 2020 Nov 09
Recruiting
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Publications & Presentations

PubMed

Layered plaque is associated with high levels of vascular inflammation and vulnerability in patients with stable angina pectoris.
Takayuki Niida, Daisuke Kinoshita, Keishi Suzuki, Haruhito Yuki, Daichi Fujimoto, Damini Dey, Hang Lee, Iris McNulty, Taishi Yonetsu, Tsunekazu Kakuta, Maros Ferencik,...> ;Journal of Thrombosis and Thrombolysis. 2024 Apr 22
Sex-Specific Association Between Perivascular Inflammation and Plaque Vulnerability.
Daisuke Kinoshita, Keishi Suzuki, Haruhito Yuki, Takayuki Niida, Daichi Fujimoto, Yoshiyasu Minami, Damini Dey, Hang Lee, Iris McNulty, Junya Ako, Maros Ferencik, Tsun...> ;Circulation. Cardiovascular Imaging. 2024 Feb 1
Cardiac Optical Coherence Tomography: History, Current Status, and Perspective.
Taishi Yonetsu, Ik-Kyung Jang> ;JACC. Asia. 2024 Feb 1
Proteomics associated with coronary high-risk plaques by optical coherence tomography.
Takayuki Niida, Haruhito Yuki, Keishi Suzuki, Daisuke Kinoshita, Daichi Fujimoto, Akihiro Nakajima, Iris McNulty, Hang Lee, Kahraman Tanriverdi, Sunao Nakamura, Ik-Kyu...> ;Journal of Thrombosis and Thrombolysis. 2024 Feb 1
Higher Noncalcified Plaque Volume Is Associated With Increased Plaque Vulnerability and Vascular Inflammation.
Keishi Suzuki, Daisuke Kinoshita, Haruhito Yuki, Takayuki Niida, Tomoyo Sugiyama, Taishi Yonetsu, Makoto Araki, Akihiro Nakajima, Lena Marie Seegers, Damini Dey, Hang ...> ;Circulation. Cardiovascular Imaging. 2024 Jan 1
1 citations
Protruding Aortic Plaque and Coronary Plaque Vulnerability.
Yuki, H., Niida, T., Suzuki, K., Kinoshita, D., Fujimoto, D., Lee, H., McNulty, I., Nakamura, S., Kakuta, T., Isselbacher, E., Jang, I.> ;Journal of the American Heart Association. 2024 Jan 16
A novel deep learning model for a computed tomography diagnosis of coronary plaque erosion.
Park, S., Yuki, H., Niida, T., Suzuki, K., Kinoshita, D., McNulty, I., Broersen, A., Dijkstra, J., Lee, H., Kakuta, T., Ye, J., Jang, I.> ;Scientific Reports. 2023 Dec 27
Author Correction: Optical coherence tomography in coronary atherosclerosis assessment and intervention.
Makoto Araki, Seung-Jung Park, Harold L Dauerman, Shiro Uemura, Jung-Sun Kim, Carlo Di Mario, Thomas W Johnson, Giulio Guagliumi, Adnan Kastrati, Michael Joner, Niels ...> ;Nature Reviews. Cardiology. 2024 May 1
Coronary Plaque Characteristics and Underlying Mechanism of Acute Coronary Syndromes in Different Age Groups of Patients With Diabetes.
Keishi Suzuki, Takayuki Niida, Haruhito Yuki, Daisuke Kinoshita, Daichi Fujimoto, Hang Lee, Iris McNulty, Masamichi Takano, Sunao Nakamura, Tsunekazu Kakuta, Kyoichi M...> ;Journal of the American Heart Association. 2023 Dec 5
Coronary artery disease reporting and data system (CAD-RADS), vascular inflammation and plaque vulnerability.
Daisuke Kinoshita, Keishi Suzuki, Haruhito Yuki, Takayuki Niida, Daichi Fujimoto, Yoshiyasu Minami, Damini Dey, Hang Lee, Iris McNulty, Junya Ako, Brian Ghoshhajra, Ma...> ;Journal of Cardiovascular Computed Tomography. 2023 Oct 8
Cardiovascular Risk Factors and Culprit Plaque Characteristics in Women With Acute Coronary Syndromes.
Lena Marie Seegers, Doreen DeFaria Yeh, Malissa J Wood, Taishi Yonetsu, Yoshiyasu Minami, Makoto Araki, Akihiro Nakajima, Haruhito Yuki, Junya Ako, Tsunenari Soeda, Os...> ;The American Journal of Cardiology. 2023 Nov 15
2 citations
High-Risk Plaques on Coronary Computed Tomography Angiography: Correlation With Optical Coherence Tomography.
Daisuke Kinoshita, Keishi Suzuki, Eisuke Usui, Masahiro Hada, Haruhito Yuki, Takayuki Niida, Yoshiyasu Minami, Hang Lee, Iris McNulty, Junya Ako, Maros Ferencik, Tsune...> ;JACC. Cardiovascular Imaging. 2024 Apr 1
1 citations
Coronary Computed Tomography Angiography Findings of Plaque Erosion.
Keishi Suzuki, Daisuke Kinoshita, Tomoyo Sugiyama, Haruhito Yuki, Takayuki Niida, Damini Dey, Hang Lee, Iris McNulty, Maros Ferencik, Tsunekazu Kakuta, Ik-Kyung Jang> ;The American Journal of Cardiology. 2023 Jun 1
1 citations
Impact of acute and persistent stent malapposition after percutaneous coronary intervention on adverse cardiovascular outcomes.
Marco Lombardi, Juan G Chiabrando, Enrico Romagnoli, Domenico D'Amario, Antonio M Leone, Cristina Aurigemma, Rocco A Montone, Alfredo Ricchiuto, Giuseppe Biondi-Zoccai...> ;Minerva Cardiology and Angiology. 2023 Oct 1
2 citations
Layered plaque and plaque volume in patients with acute coronary syndromes.
Haruhito Yuki, Daisuke Kinoshita, Keishi Suzuki, Takayuki Niida, Akihiro Nakajima, Lena Marie Seegers, Rocco Vergallo, Francesco Fracassi, Michele Russo, Luca Di Vito,...> ;Journal of Thrombosis and Thrombolysis. 2023 Apr 1
5 citations
Coronary Inflammation and Plaque Vulnerability: A Coronary Computed Tomography and Optical Coherence Tomography Study.
Haruhito Yuki, Tomoyo Sugiyama, Keishi Suzuki, Daisuke Kinoshita, Takayuki Niida, Akihiro Nakajima, Makoto Araki, Damini Dey, Hang Lee, Iris McNulty, Sunao Nakamura, T...> ;Circulation. Cardiovascular Imaging. 2023 Mar 1
1 citations
Diagnosis of coronary layered plaque by deep learning.
Makoto Araki, Sangjoon Park, Akihiro Nakajima, Hang Lee, Jong Chul Ye, Ik-Kyung Jang> ;Scientific Reports. 2023 Feb 10
3 citations
Intracoronary Imaging of Vulnerable Plaque-From Clinical Research to Everyday Practice.
Jacek Legutko, Krzysztof L Bryniarski, Grzegorz L Kaluza, Tomasz Roleder, Elzbieta Pociask, Elvin Kedhi, Wojciech Wojakowski, Ik-Kyung Jang, Pawel Kleczynski> ;Journal of Clinical Medicine. 2022 Nov 9
4 citations
Level of Vascular Inflammation Is Higher in Acute Coronary Syndromes Compared with Chronic Coronary Disease.
Makoto Araki, Tomoyo Sugiyama, Akihiro Nakajima, Taishi Yonetsu, Lena Marie Seegers, Damini Dey, Hang Lee, Iris McNulty, Yumi Yasui, Yun Teng, Tatsuhiro Nagamine, Tsun...> ;Circulation. Cardiovascular Imaging. 2022 Nov 1
5 citations
Biomarkers associated with coronary high-risk plaques.
Akihiro Nakajima, Peter Libby, Satoru Mitomo, Haruhito Yuki, Makoto Araki, Lena Marie Seegers, Iris McNulty, Hang Lee, Midori Ishibashi, Kazuna Kobayashi, Jouke Dijkst...> ;Journal of Thrombosis and Thrombolysis. 2022 Nov 1
5 citations
Enhanced Diagnosis of Plaque Erosion by Deep Learning in Patients With Acute Coronary Syndromes.
Sangjoon Park, Makoto Araki, Akihiro Nakajima, Hang Lee, Valentin Fuster, Jong Chul Ye, Ik-Kyung Jang> ;JACC. Cardiovascular Interventions. 2022 Oct 24
91 citations
Optical coherence tomography in coronary atherosclerosis assessment and intervention.
Makoto Araki, Seung-Jung Park, Harold L Dauerman, Shiro Uemura, Jung-Sun Kim, Carlo Di Mario, Thomas W Johnson, Giulio Guagliumi, Adnan Kastrati, Michael Joner, Niels ...> ;Nature Reviews. Cardiology. 2022 Oct 1
15 citations
Gut Microbiota and Coronary Plaque Characteristics.
Akihiro Nakajima, Satoru Mitomo, Haruhito Yuki, Makoto Araki, Lena Marie Seegers, Iris McNulty, Hang Lee, David Kuter, Midori Ishibashi, Kazuna Kobayashi, Jouke Dijkst...> ;Journal of the American Heart Association. 2022 Sep 6
1 citations
High endothelial shear stress and stress gradient at plaque erosion persist up to 12 months.
Hyung Oh Kim, Bo Jiang, Eric K W Poon, Vikas Thondapu, Chong-Jin Kim, Osamu Kurihara, Makoto Araki, Akihiro Nakajima, Chris Mamon, Jouke Dijkstra, Hang Lee, Andrew Ooi...> ;International Journal of Cardiology. 2022 Jun 15
16 citations
Sex Differences in Culprit Plaque Characteristics Among Different Age Groups in Patients With Acute Coronary Syndromes.
Lena Marie Seegers, Makoto Araki, Akihiro Nakajima, Taishi Yonetsu, Yoshiyasu Minami, Junya Ako, Tsunenari Soeda, Osamu Kurihara, Takumi Higuma, Shigeki Kimura, Tom Ad...> ;Circulation. Cardiovascular Interventions. 2022 Jun 1
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