Irene Wapnir MD FACS

General Surgery•Palo Alto, CA

Breast, Surgical Oncology (Other than Breast)

Professor of Surgery, Director of Breast Fellowship Program

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300 Pasteur DrPalo Alto, CA 94304
Phone+1 650-723-4000
Fax+1 650-736-1663

Education & Training

Rutgers Robert Wood Johnson Medical SchoolFellowship, Breast Surgical Oncology, 1988
Lincoln Medical and Mental Health CenterResidency, Surgery, 1980 - 1985
Autonomous Metropolitan University XochimilcoClass of 1980

Certifications & Licensure

CA State Medical License 2001 - 2026
NJ State Medical License 1987 - 2005
NY State Medical License 1984 - 2005
MD State Medical License 1982 - 1995
American Board of Surgery Surgery

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2012-2014, 2018
America's Top Doctors for Cancer Castle Connolly, 2011-2013
CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2011-2013
Fellow (FACS) American College of Surgeons
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Clinical Trials

Adjuvant Chemotherapy in Treating Women Who Have Undergone Resection for Relapsed Breast Cancer; Chemotherapy as Adjuvant for LOcally Recurrent Breast Cancer Start of enrollment: 2002 Jul 01
Completed
Phase 3
Scintigraphic Assessment of I- Transport in Metastatic Breast Cancer and Evaluation of I31I Ablative Therapy: (Part I) Radioiodide Imaging Study Start of enrollment: 2000 Nov 01
Completed
Immunohistochemical & Immunoblot Analysis of NIS (Na+/I-Symporter) in Archival & Frozen Tissue Sample Start of enrollment: 2000 Oct 01
Completed
Pilot Study to Determine Radioiodide Accumulation and Dosimetry in Breast Cancers Using 124I PET/CT Start of enrollment: 2008 Feb 01
Terminated
Early Phase 1
Radiation Therapy With or Without Trastuzumab in Treating Women With Ductal Carcinoma In Situ Who Have Undergone Lumpectomy Start of enrollment: 2008 Nov 10
ACTIVE_NOT_RECRUITING
PHASE3
Chemotherapy With or Without Trastuzumab After Surgery in Treating Women With Invasive Breast Cancer Start of enrollment: 2011 Jan 06
ACTIVE_NOT_RECRUITING
PHASE3
SPY Intra-Operative Angiography & Skin Perfusion in Immediate Breast Reconstruction w/ Implants Start of enrollment: 2011 Jun 01
Completed
Radioactive Iodide (131I) Treatment of 124I PET/CT Detected Breast Cancers Start of enrollment: 2010 Jul 01
Withdrawn
Not Applicable
Pilot Indocyanine Green Imaging for Mapping of Arm Draining Lymphatics & Nodes in Breast Cancer Start of enrollment: 2012 Jul 01
Completed
Phase 2
Doxorubicin Hydrochloride and Cyclophosphamide Followed by Paclitaxel With or Without Carboplatin in Treating Patients With Triple-Negative Breast Cancer Start of enrollment: 2015 Jul 26
Active, not recruiting
Phase 3
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Publications & Presentations

PubMed

Lumpectomy surgery for large ductal carcinoma in situ.
Daniela Bresciani Padilla, Jacqueline Tsai, Amanda Sutherland Beck, Irene L Wapnir
Breast Cancer Research and Treatment. 2025-05-01
5 citations
Survival with Trastuzumab Emtansine in Residual HER2-Positive Breast Cancer.
Charles E Geyer Jr, Michael Untch, Chiun-Sheng Huang, Max S Mano, Eleftherios P Mamounas
The New England Journal of Medicine. 2025-01-16
Residual cancer burden in two-stage nipple sparing mastectomy after first stage lumpectomy and devascularization of the nipple areolar complex.
Candice N Thompson, Julia Chandler, Tammy Ju, Jacqueline Tsai, Irene Wapnir
Breast Cancer Research and Treatment. 2024-08-01

Journal Articles

Matching for Fellowship Interviews
Marc L Melcher, Irene Wapnir, JAMA

Press Mentions

Stanford 1st in U.S. To Employ Fluorescent Imaging SystemMay 2nd, 2025
Stanford Medicine the First to Use Imaging System That Lights up Tumor Margins IntraoperativelyMay 1st, 2025
New Imaging Technology Helps Stanford Medicine Surgeons Reduce Repeat Breast SurgeriesApril 30th, 2025
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Professional Memberships

American Society of Clinical Oncology - ASCO
Member
American College of Surgeons - ACS
Member

Other Languages

Spanish