IrmaMSainzMD

PubMed

• 147 citations
  Napsin A, a new marker for lung adenocarcinoma, is complementary and more sensitive and specific than thyroid transcription factor 1 in the differential diagnosis of p...
  Bradley M. Turner, Philip T. Cagle, Irma M. Sainz, Junya Fukuoka, Steven S. Shen, Jaishree Jagirdar> ;Archives of Pathology & Laboratory Medicine. 2012 Jan 30
• 34 citations
  Association of the Plasminogen Activator Inhibitor-1 Gene 4G/5G Polymorphism With ST Elevation Acute Myocardial Infarction in Young Patients
  Irma Isordia-Salas, Alfredo Leaños-Miranda, Irma M. Sainz, Elba Reyes-Maldonado, Gabriela Borrayo-Sánchez> ;Revista Espanola De Cardiologia. 2009 Apr 1
• 19 citations
  The inhibitory effect of HKa in endothelial cell tube formation is mediated by disrupting the uPA-uPAR complex and inhibiting its signaling and internalization.
  Yuchuan Liu, Dian J. Cao, Irma M. Sainz, Yan Lin Guo, Robert W. Colman> ;American Journal of Physiology. Cell Physiology. 2008 Jul 1
• 18 citations
  THE INHIBITION OF TUBE FORMATION IN A COLLAGEN-FIBRINOGEN, THREE-DIMENSIONAL GEL BY CLEAVED KININOGEN (HKa) AND HK DOMAIN 5 (D5) IS DEPENDENT ON Src FAMILY KINASES
  Yuchuan Liu, Irma M. Sainz, Yi Wu, Robin A. Pixley, Ricardo G. Espinola, Sarmina Hassan, Mohammad M. Khan, Robert W. Colman> ;Experimental Cell Research. 2008 Feb 15
• 18 citations
  Kininostatin Associates With Membrane Rafts and Inhibits αvβ3 Integrin Activation in Human Umbilical Vein Endothelial Cells
  Yi Wu, Victor Rizzo, Yuchuan Liu, Irma M. Sainz, Noah G. Schmuckler, Robert W. Colman> ;Arteriosclerosis, Thrombosis, and Vascular Biology. 2007 Sep 1
• 107 citations
  Fifty years of research on the plasma kallikrein-kinin system: From protein structure and function to cell biology and in-vivo pathophysiology
  Irma M. Sainz, Robin A. Pixley, Robert W. Colman> ;Thrombosis and Haemostasis. 2007 Jul 1
• 9 citations
  Antithrombotic activity of kininogen is mediated by inhibitory effects of domain 3 during arterial injury in vivo
  Sarmina Hassan, Irma M. Sainz, Mohammad M. Khan, Harlan N. Bradford, Irma Isordia-Salas, Sakeen W. Kashem, R. Balfour Sartor, Robert W. Colman> ;American Journal of Physiology. Heart and Circulatory Physiology. 2007 Jun 1
• 25 citations
  Amelioration of inflammation, angiogenesis and CTGF expression in an arthritis model by a TSP1-derived peptide treatment.
  Mario C. Rico, Julian L. Castaneda, Joanne M. Manns, Audrey B. Uknis, Irma M. Sainz, Fayez F. Safadi, S.N. Popoff, Raul A. DeLa Cadena> ;Journal of Cellular Physiology. 2007 May 1
• 8 citations
  Multiple myeloma in a murine syngeneic model:modulation of growth and angiogenesis by a monoclonal antibody to kininogen
  Irma M. Sainz, Irma Isordia-Salas, Ricardo G. Espinola, Walter K. Long, Robin A. Pixley, Robert W. Colman> ;Cancer Immunology, Immunotherapy. 2006 Jul 1
• 5 citations
  [High molecular weight kininogen in inflammation and angiogenesis: a review of its properties and therapeutic applications].
  Irma Isordia-Salas, Irma M. Sainz, Robin A. Pixley, Carlos Martínez-Murillo, Robert W. Colman> ;Revista De Investigacion Clinica; Organo Del Hospital De Enfermedades De La Nutricion. 2005 Nov 1
• 20 citations
  Modulation of Inflammation by Kininogen Deficiency in a Rat Model of Inflammatory Arthritis
  Irma M. Sainz, Irma Isordia-Salas, Julian L. Castaneda, Alexis Agelan, Bo Liu, Raul A. DeLa Cadena, Robin A. Pixley, Albert Adam, R. Balfour Sartor, Robert W. Colman> ;Arthritis and Rheumatism. 2005 Aug 1
• 16 citations
  The role of plasma high molecular weight kininogen in experimental intestinal and systemic inflammation.
  Irma Isordia-Salas, Robin A Pixley, Irma M Sáinz, Carlos Martínez-Murillo, Robert W Colman> ;Archives of Medical Research. 2005 May 19
• 15 citations
  A monoclonal antibody against kininogen reduces inflammation in the HLA-B27 transgenic rat.
  James C. Keith, Irma M. Sainz, Irma Isordia-Salas, Robin A. Pixley, Yelena Leathurby, Leo M. Albert, Robert W. Colman> ;Arthritis Research & Therapy. 2005 Apr 4
• 7 citations
  Thromsbospondin-1 binds to the heavy chain of elastase activated coagulation factor V (FVaHNE) and enhances thrombin generation on the surface of a promyelocytic cell ...
  Irma Isordia-Salas, Joanne M. Manns, Irma M. Sainz, Hemant K. Parekh, Raul A. DeLa Cadena> ;Thrombosis Research. 2005 Jan 1
• 27 citations
  Inhibition of tumor angiogenesis in vivo by a monoclonal antibody targeted to domain 5 of high molecular weight kininogen
  James S. Song, Irma M. Sainz, Stephen C. Cosenza, Irma Isordia-Salas, Abdel Bior, Harlan N. Bradford, Yan-Lin Guo, Robin A. Pixley, E. Premkumar Reddy, Robert W. Colman> ;Blood. 2004 Oct 1
• 52 citations
  Different roles of ERK and p38 MAP kinases during tube formation from endothelial cells cultured in 3-dimensional collagen matrices
  Baohua Yang, Dian J. Cao, Irma M. Sainz, Robert W. Colman, Yan Lin Guo> ;Journal of Cellular Physiology. 2004 Sep 1
• 18 citations
  A Monoclonal Antibody to High-Molecular Weight Kininogen Is Therapeutic in a Rodent Model of Reactive Arthritis
  Ricardo G. Espinola, Audrey B. Uknis, Irma M. Sainz, Irma Isordia-Salas, Robin A. Pixley, Raul A. DeLa Cadena, Walter K. Long, Alexis Agelan, John P. Gaughan, Albert A...> ;The American Journal of Pathology. 2004 Sep 1
• The role of plasma high molecular weight kininogen in experimental intestinal and systemic inflammation.
  Isordia-Salas, I., Pixley, R. A., Sáinz, I. M., Martínez-Murillo, C., Colman, R. W.> ;Arch Med Res. 2004-09-01
• 26 citations
  Interactions between bradykinin (BK) and cell adhesion molecule (CAM) expression in peptidoglycan-polysaccharide (PG-PS)-induced arthritis
  Irma M. Sainz, Audrey B. Uknis, Irma Isordia-Salas, R A DeLa Cadena, Robin A. Pixley, Robert W. Colman> ;FASEB Journal. 2004 May 1
• 56 citations
  Inhibition of angiogenesis by antibody blocking the action of proangiogenic high-molecular-weight kininogen.
  Robert W. Colman, Robin A. Pixley, Irma M. Sainz, J. S. Song, Irma Isordia-Salas, S. N. Muhamed, J. A. J. Powell, Shaker A. Mousa> ;Journal of Thrombosis and Haemostasis. 2003 Jan 1
• 7 citations
  Chronic intestinal inflammation and angiogenesis in genetically susceptible rats is modulated by kininogen deficiency.
  Irma Isordia-Salas, Robin A. Pixley, Fengling Li, Irma M. Sainz, R. Balfour Sartor, Albert Adam, Robert W. Colman> ;International Immunopharmacology. 2002 Dec 1
• 22 citations
  Kininogen deficiency modulates chronic intestinal inflammation in genetically susceptible rats.
  Irma Isordia-Salas, Robin A. Pixley, Fengling Li, Irma M. Sainz, R. Balfour Sartor, Albert Adam, Robert W. Colman> ;American Journal of Physiology. Gastrointestinal and Liver Physiology. 2002 Jul 1
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