IsabelleGDe PlaenMD

PubMed

• 2 citations
  Feeding mode influences dynamic gut microbiota signatures and affects susceptibility to anti-CD3 mAb-induced intestinal injury in neonatal mice.
  Saravanan Subramanian, Hua Geng, Chao Du, Pauline M Chou, Heng-Fu Bu, Xiao Wang, Suchitra Swaminathan, Stephanie C Tan, Jason M Ridlon, Isabelle G De Plaen, Xiao-Di Tan> ;American Journal of Physiology. Gastrointestinal and Liver Physiology. 2022 Sep 1
• 7 citations
  Macrophage-derived IGF-1 protects the neonatal intestine against necrotizing enterocolitis by promoting microvascular development.
  Xiaocai Yan, Elizabeth Managlia, You-Yang Zhao, Xiao-Di Tan, Isabelle G De Plaen> ;Communications Biology. 2022 Apr 6
• 5 citations
  Intestinal Epithelial Barrier Function and Necrotizing Enterocolitis.
  Elizabeth Managlia, Xiaocai Yan, Isabelle G De Plaen> ;Newborn. 2022 Mar 31
• 5 citations
  Current Understanding of Transfusion-associated Necrotizing Enterocolitis: Review of Clinical and Experimental Studies and a Call for More Definitive Evidence.
  Minesh Khashu, Christof Dame, Pascal M Lavoie, Isabelle G De Plaen, Parvesh M Garg, Venkatesh Sampath, Atul Malhotra, Michael D Caplan, Praveen Kumar, Pankaj B Agrawal...> ;Newborn. 2022 Mar 31
• 9 citations
  Human Milk Growth Factors and Their Role in NEC Prevention: A Narrative Review.
  Daniel J York, Anne L Smazal, Daniel T. Robinson, Isabelle G. De Plaen> ;Nutrients. 2021 Oct 23
• 2 citations
  MFG-E8 Plays an Important Role in Attenuating Cerulein-Induced Acute Pancreatitis in Mice
  Heng-Fu Bu, Saravanan Subramanian, Hua Geng, Xiao Wang, Pauline M. Chou, Chao Du, Isabelle G. De Plaen, Xiao-Di Tan, Fangyi Liu> ;Cells. 2021 Mar 25
• 28 citations
  SARS-CoV-2 ORF8 Forms Intracellular Aggregates and Inhibits IFNγ-Induced Antiviral Gene Expression in Human Lung Epithelial Cells.
  Hua Geng, Saravanan Subramanian, Longtao Wu, Heng-Fu Bu, Xiao Wang, Chao Du, Isabelle G. De Plaen, Xiao-Di Tan> ;Frontiers in Immunology. 2021 Jan 1
• 8 citations
  Recent Advances in Necrotizing Enterocolitis Research: Strategies for Implementation in Clinical Practice.
  Mohan Pammi, Isabelle G. De Plaen, Akhil Maheshwari> ;Clinics in Perinatology. 2020 Jun 1
• 1 citations
  Interferon-γ inhibits sirtuin 6 gene expression in intestinal epithelial cells through a microRNA-92b-dependent mechanism
  Xiao Wang, Hua Geng, Heng-Fu Bu, Peng Wang, Isabelle G. De Plaen, Hong Yang, Jiaming Qian, Xiao-Di Tan, Fangyi Liu> ;American Journal of Physiology. Cell Physiology. 2020 Feb 12
• 26 citations
  Prenatal inflammation impairs intestinal microvascular development through a TNF-dependent mechanism and predisposes newborn mice to necrotizing enterocolitis
  Xiaocai Yan, Elizabeth Managlia, Xiao-Di Tan, Isabelle G. De Plaen> ;American Journal of Physiology. Gastrointestinal and Liver Physiology. 2019 Jul 1
• 26 citations
  Blocking NF-κB Activation in Ly6c+ Monocytes Attenuates Necrotizing Enterocolitis.
  Elizabeth Managlia, Shirley X.L. Liu, Xiaocai Yan, Xiao-Di Tan, Pauline M. Chou, Terrence A. Barrett, Isabelle G. De Plaen> ;The American Journal of Pathology. 2019 Mar 1
• 52 citations
  Intestinal microcirculation and necrotizing enterocolitis: The vascular endothelial growth factor system
  Rakhee M. Bowker, Xiaocai Yan, Isabelle G. De Plaen> ;Seminars in Fetal & Neonatal Medicine. 2018 Dec 1
• 121 citations
  In Inflamed Intestinal Tissues and Epithelial Cells, Interleukin 22 Signaling Increases Expression of H19 Long Noncoding RNA, Which Promotes Mucosal Regeneration
  Hua Geng, Heng-Fu Bu, Longtao Wu, Karl Pfeifer, Pauline M. Chou, Xiao Wang, Jiaren Sun, Lu Lu, Ashutosh K. Pandey, Marisa S. Bartolomei, Isabelle G. De Plaen, Peng Wan...> ;Gastroenterology. 2018 Jul 1
• 21 citations
  Dimethyloxalylglycine preserves the intestinal microvasculature and protects against intestinal injury in a neonatal mouse NEC model: role of VEGF signaling
  Rakhee M. Bowker, Xiaocai Yan, Elizabeth Managlia, Shirley X.L. Liu, Catherine Marek, Xiao-Di Tan, Isabelle G. De Plaen> ;Pediatric Research. 2018 Feb 1
• 90 citations
  Epithelial TNF Receptor Signaling Promotes Mucosal Repair in Inflammatory Bowel Disease.
  Emily M. Bradford, Stacy H. Ryu, Ajay Pal Singh, Goo Lee, Tatiana Goretsky, Preetika Sinh, David Williams, Amber L. Cloud, Elias Gounaris, Vihang Patel, Olivia F. Lamp...> ;Journal of Immunology. 2017 Sep 1
• 16 citations
  A Role for cAMP and Protein Kinase A in Experimental Necrotizing Enterocolitis
  Brian P. Blackwood, Douglas R. Wood, Carrie Yuan, Joseph D. Nicolas, Isabelle G. De Plaen, Kathryn N. Farrow, Pauline M. Chou, Jerrold R. Turner, Catherine J. Hunter> ;The American Journal of Pathology. 2017 Feb 1
• 14 citations
  Sirtuin-6 preserves R-spondin-1 expression and increases resistance of intestinal epithelium to injury in mice.
  Fangyi Liu, Heng-Fu Bu, Hua Geng, Isabelle G. De Plaen, Chao Gao, Peng Wang, Xiao Wang, Jacob Kurowski, Hong Yang, Jiaming Qian, Xiao-Di Tan> ;Molecular Medicine. 2017 Oct 23
• 22 citations
  Spherical nucleic acid targeting microRNA-99b enhances intestinal MFG-E8 gene expression and restores enterocyte migration in lipopolysaccharide-induced septic mice.
  Xiao Wang, Liangliang Hao, Heng-Fu Bu, Alexander W. Scott, Ke Tian, Isabelle G. De Plaen, Yulan Liu, Chad A. Mirkin, Xiao-Di Tan, Fangyi Liu> ;Scientific Reports. 2016 Aug 19
• 7 citations
  Epithelial PIK3R1 (p85) and TP53 Regulate Survivin Expression during Adaptation to Ileocecal Resection.
  Valeria C. Cohran, Elizabeth Managlia, Emily M. Bradford, Tatiana Goretsky, Ting Li, Rebecca B. Katzman, Paul Cheresh, Jeffrey B. Brown, Jennifer Hawkins, Shirley X.L....> ;The American Journal of Pathology. 2016 Jul 1
• 41 citations
  Lack of VEGFR2 signaling causes maldevelopment of the intestinal microvasculature and facilitates necrotizing enterocolitis in neonatal mice
  Xiaocai Yan, Elizabeth Managlia, Shirley X.L. Liu, Xiao-Di Tan, Xiao Wang, Catherine Marek, Isabelle G. De Plaen> ;American Journal of Physiology. Gastrointestinal and Liver Physiology. 2016 May 1
• 8 citations
  Molecular Mechanisms Underlying the Regulation of the MFG‐E8 Gene Promoter Activity in Physiological and Inflammatory Conditions
  Xiao Wang, Heng-Fu Bu, Shirley X.L. Liu, Isabelle G. De Plaen, Xiao-Di Tan> ;Journal of Cellular Biochemistry. 2015 Sep 1
• 31 citations
  Intestinal vascular endothelial growth factor is decreased in necrotizing enterocolitis.
  Animesh Sabnis, Rosa Carrasco, Shirley X.L. Liu, Xiaocai Yan, Elizabeth Managlia, Pauline M. Chou, Xiao-Di Tan, Isabelle G. De Plaen> ;Neonatology. 2015 Jan 30
• 63 citations
  Inflammatory signaling in NEC: Role of NF-κB, cytokines and other inflammatory mediators.
  Catherine J. Hunter, Isabelle G. De Plaen> ;Pathophysiology. 2014 Feb 1
• 163 citations
  Bifidobacteria Stabilize Claudins at Tight Junctions and Prevent Intestinal Barrier Dysfunction in Mouse Necrotizing Enterocolitis
  Kelly R. Bergmann, Shirley X.L. Liu, Runlan Tian, Anna Kushnir, Jerrold R. Turner, Hong Lin Li, Pauline M. Chou, Christopher R. Weber, Isabelle G. De Plaen> ;The American Journal of Pathology. 2013 May 1
• 52 citations
  Inflammatory Signaling in Necrotizing Enterocolitis
  Isabelle G. De Plaen> ;Clinics in Perinatology. 2013 Mar 1
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