IsaiahRichardTurnbullMD

General Surgery • Saint Louis, MO

Trauma Surgery & Surgical Critical Care

Physician

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Office
1 Barnes Jewish Hospital Plz
Saint Louis, MO 63110
Phone+1 314-286-1050

Fax+1 314-286-1051
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Education & Training

Washington University/B-JH/SLCH ConsortiumFellowship, Surgical Critical Care, 2013 - 2014
Washington University/B-JH/SLCH ConsortiumResidency, Surgery, 2008 - 2013
Washington University in St. Louis School of MedicineClass of 2008

Certifications & Licensure

IL State Medical License 2019 - 2026
MO State Medical License 2013 - 2025
American Board of Surgery Surgery
American Board of Surgery Surgical Critical Care

Awards, Honors, & Recognition

Fellow (FACS) American College of Surgeons

Publications & Presentations

PubMed

Defects in vein valve PROX1/FOXC2 antithrombotic pathway in endothelial cells drive the hypercoagulable state induced by trauma and critical illness.
Mark H Hoofnagle, Annie Hess, Margaret Nalugo, Sarbani Ghosh, Shin-Wen Hughes, Anja Fuchs, John D Welsh, Mark L Kahn, Grant V Bochicchio, Gwendalyn J Randolph, Jennife...> ;The Journal of Trauma and Acute Care Surgery. 2023 Aug 1
3 citations
IL-1β expression in bone marrow dendritic cells is induced by TLR2 agonists and regulates HSC function.
Sidan Li, Juo-Chin Yao, Karolyn A Oetjen, Joseph R Krambs, Jun Xia, Jingzhu Zhang, Amy P Schmidt, Nichole M Helton, Robert S Fulton, Sharon E Heath, Isaiah R Turnbull,...> ;Blood. 2022 Oct 6
2 citations
Cellular immunophenotype of major spine surgery in adults.
Isaiah R Turnbull, Annie Hess, Anja Fuchs, Elfaridah P Frazier, Sarbani Ghosh, Shin-Wen Hughes, Michael P Kelly> ;Spine Deformity. 2022 Nov 1
3 citations
Dysregulation of the leukocyte signaling landscape during acute COVID-19.
Isaiah R Turnbull, Anja Fuchs, Kenneth E Remy, Michael P Kelly, Elfaridah P Frazier, Sarbani Ghosh, Shin-Wen Chang, Monty B Mazer, Annie Hess, Jennifer M Leonard, Mark...> ;Plos One. 2022 Jan 1
11 citations
Interleukin-7 Reverses Lymphopenia and Improves T-Cell Function in Coronavirus Disease 2019 Patient With Inborn Error of Toll-Like Receptor 3: A Case Report
Monty Mazer, Isaiah R. Turnbull, S. Miles, Teresa M. Blood, Brooke Sadler, A. Hess, M. D. Botney, R. S. Martin, James P. Bosanquet, David A. Striker, N. S. Anand, M. M...> ;Critical Care Explorations. 2021 Jul 14
7 citations
Extrathoracic multiple trauma dysregulates neutrophil function and exacerbates pneumonia-induced lung injury.
Jennifer M. Leonard, Christina X. Zhang, Liang Lu, Mark H. Hoofnagle, Anja Fuchs, Regina A. Clemens, Sarbani Ghosh, Shin-Wen Hughes, Grant V. Bochicchio, Richard S. Ho...> ;The Journal of Trauma and Acute Care Surgery. 2021 Jun 1
10 citations
IL-7 Immunotherapy in a Nonimmunocompromised Patient With Intractable Fungal Wound Sepsis.
Isaiah R. Turnbull, Monty Mazer, Mark H. Hoofnagle, John P. Kirby, Jennifer M. Leonard, Carlos Mejia-Chew, Andrej Spec, Jane Blood, Sydney M Miles, Eric M. Ransom, Rob...> ;Open Forum Infectious Diseases. 2021 May 23
1 citations
Pseudomonas aeruginosa Pneumonia Causes a Loss of Type-3 and an Increase in Type-1 Innate Lymphoid Cells in the Gut.
Anja Fuchs, Sarbani Ghosh, Shin-Wen Chang, Grant V. Bochicchio, Isaiah R. Turnbull> ;The Journal of Surgical Research. 2021 May 2
4 citations
In Vitro-Administered Dexamethasone Suppresses T Cell Function With Reversal by Interleukin-7 in Coronavirus Disease 2019
Monty Mazer, Ethan Davitt, Isaiah R. Turnbull, Charles C. Caldwell, Scott C. Brakenridge, Kenneth E. Remy, Richard S. Hotchkiss> ;Critical Care Explorations. 2021 Apr 2
What's New in Shock, March 2021?
Steven J. Schwulst, Isaiah R. Turnbull> ;Shock. 2021 Mar 1
2 citations
Dysregulation of the Leukocyte Signaling Landscape during Acute COVID-19
Isaiah R. Turnbull, Anja Fuchs, Kenneth E. Remy, Michael Kelly, Elfaridah Frazier, Sarbani Ghosh, Shin-Wen Chang, Monty Mazer, Annie Hess, Jennifer M. Leonard, Mark H....> ;Research Square. 2021 Feb 16
2 citations
SAVE 2.0: Identifying and strengthening resident leadership skills through simulation based team training.
Emily J. Onufer, Erin G. Andrade, Katharine E. Caldwell, Darren R. Cullinan, Kelly Vallar, Isaiah R. Turnbull, Douglas J. E. Schuerer, Paul E. Wise, Mary E. Klingensmi...> ;The Journal of Trauma and Acute Care Surgery. 2021 Mar 1
16 citations
A Whole Blood Enzyme-Linked Immunospot Assay for Functional Immune Endotyping of Septic Patients.
Monty Mazer, Charles C. Caldwell, Jodi Hanson, Daniel A. Mannion, Isaiah R. Turnbull, Anne M. Drewry, Dale F. Osborne, Andrew H. Walton, Tessa Blood, Lyle L. Moldawer,...> ;Journal of Immunology. 2021 Jan 1
2 citations
Ethics of Codes and Codes of Ethics: When Is It Ethical to Provide Cardiopulmonary Resuscitation During the COVID-19 Pandemic?
Piroska K. Kopar, Douglas Brown, Isaiah R. Turnbull> ;Annals of Surgery. 2020 Dec 1
20 citations
Macrophage-Derived Vascular Endothelial Growth Factor-A Is Integral to Neuromuscular Junction Reinnervation after Nerve Injury.
Chuieng-Yi Lu, Katherine B. Santosa, Albina Jablonka-Shariff, Bianca Vannucci, Anja Fuchs, Isaiah R. Turnbull, Deng Pan, Matthew D. Wood, Alison K. Snyder-Warwick> ;The Journal of Neuroscience. 2020 Nov 6
22 citations
The Immunologic Effect of Early Intravenous Two and Four Gram Bolus Dosing of Tranexamic Acid Compared to Placebo in Patients With Severe Traumatic Bleeding (TAMPITI):...
Philip C. Spinella, Kimberly A. Thomas, Isaiah R. Turnbull, Anja Fuchs, Kelly Bochicchio, Douglas J. E. Schuerer, Stacey Reese, Adrian A Coleoglou Centeno, Christopher...> ;Frontiers in Immunology. 2020 Sep 8
216 citations
Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections.
Kenneth E. Remy, Monty Mazer, David A. Striker, Ali H. Ellebedy, Andrew H. Walton, Jacqueline Unsinger, Teresa M. Blood, Philip A. Mudd, Daehan J. Yi, Daniel A. Mannio...> ;JCI Insight. 2020 Sep 3
20 citations
IL-22 is required for the induction of bronchus-associated lymphoid tissue in tolerant lung allografts.
Satona Tanaka, Jason M. Gauthier, Anja Fuchs, Wenjun Li, Alice Y. Tong, Margaret S. Harrison, Ryuji Higashikubo, Yuriko Terada, Ramsey R. Hachem, Daniel Ruiz-Pérez, Jo...> ;American Journal of Transplantation. 2020 May 1
What's New in Shock, October 2019?
Steven J. Schwulst, Isaiah R. Turnbull> ;Shock. 2019 Oct 1
22 citations
Trauma Induces Emergency Hematopoiesis through IL-1/MyD88-Dependent Production of G-CSF.
Anja Fuchs, Darlene Monlish, Sarbani Ghosh, Shin-Wen Chang, Grant V. Bochicchio, Laura G. Schuettpelz, Isaiah R. Turnbull> ;Journal of Immunology. 2019 Apr 15
An Aspirin a Day Keeps the Intensivist Away
Isaiah R. Turnbull, Richard S. Hotchkiss> ;Critical Care Medicine. 2019 Apr 1
6 citations
Drain Failure in Intra-Abdominal Abscesses Associated with Appendicitis.
Christopher B Horn, Adrian A Coleoglou Centeno, Jarot Guerra, John E. Mazuski, Grant V. Bochicchio, Isaiah R. Turnbull> ;Surgical Infections. 2018 Apr 1
23 citations
Empiric Antibiotics for Sepsis.
Sara Buckman, Isaiah R. Turnbull, John E. Mazuski> ;Surgical Infections. 2018 Feb 1
5 citations
Antibiotic-Impregnated Central Venous Catheters Do Not Change Antibiotic Resistance Patterns
Isaiah R. Turnbull, Sara Buckman, Christopher B Horn, Grant V. Bochicchio, John E. Mazuski> ;Surgical Infections. 2018 Jan 1
17 citations
Incidence, demographics, and outcomes of nonoperative management of appendicitis in the United States
Christopher B Horn, Dajun Tian, Grant V. Bochicchio, Isaiah R. Turnbull> ;The Journal of Surgical Research. 2017 Dec 1
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