IssaF.KhouriMD

Oncology • Houston, TX

Hematologic Oncology

Physician

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Office
1515 Holcombe Blvd
Houston, TX 77030
Phone+1 713-792-6161
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Education & Training

University of Texas Health Science Center at HoustonFellowship, Hematology and Medical Oncology, 1990 - 1993
St Elizabeth Youngstown Hospital/NEOMEDResidency, Internal Medicine, 1987 - 1989
St Elizabeth Youngstown HospitalInternship, Transitional Year, 1986 - 1987
Sapienza University of RomeClass of 1983

Certifications & Licensure

FL State Medical License 2021 - Present
TX State Medical License 1990 - 2024
OK State Medical License 2020 - 2021
OH State Medical License 1988 - 2000
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Hematology
American Board of Internal Medicine Medical Oncology

Clinical Trials

Combination Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Refractory Chronic Lymphocytic Leukemia Start of enrollment: 1995 Dec 01
Completed
Phase 1, Phase 2
Safety and Efficacy of Campath in Nonmyeloablative Transplantation Start of enrollment: 2001 Jun 01
Completed
Not Applicable
Campath-1H and Allogeneic Blood Stem Cell Transplantation for Lymphoid Malignancies Start of enrollment: 2001 Apr 09
Terminated
Not Applicable
Safety and Efficacy of 90Y Zevalin in Nonmyeloablative Transplantation for Lymphoid Malignancies Start of enrollment: 2002 Oct 01
Completed
Phase 1, Phase 2
Immunotherapy With NK Cell, Rituximab and Rhu-GMCSF in Non-Myeloablative Allogeneic Stem Cell Transplantation Start of enrollment: 2006 Sep 01
Completed
Phase 1
Bortezomib and Chemotherapy in Treating Participants With Lymphoid Malignancies Undergoing Stem Cell Transplant Start of enrollment: 2007 Feb 13
Completed
Phase 2
Autologous and Allogenic Transplantation With Campath-1H for T-Cell Lymphoma Start of enrollment: 2003 Mar 01
Terminated
Phase 2
Non-Myeloablative Allogeneic Stem Cell Transplantation Start of enrollment: 2005 Jan 01
Completed
Not Applicable
Natural Killer (NK) Cell Adback After Allogeneic Stem Cell Transplant With Campath-IH Plus Chemorx for Patients With Lymphoid Malignancies Start of enrollment: 2007 Sep 01
Completed
Phase 2
Zevalin/BEAM/Rituximab vs BEAM/Rituximab With or Without Rituximab in Autologous Stem Cell Transplantation Start of enrollment: 2007 Nov 14
Completed
Phase 2
Fludarabine, Bendamustine, and Rituximab in Treating Participants With Lymphoid Cancers Undergoing Stem Cell Transplant Start of enrollment: 2009 Feb 17
Completed
Phase 1
Nonmyeloablative Stem Cell Transplantation for Chronic Lymphocytic Leukemia (CLL) Start of enrollment: 2009 May 06
Terminated
Phase 2
Chemotherapy Plus Ofatumumab Followed by G-CSF for Mobilization of Peripheral Blood Stem Cells in Patients With Non-Hodgkin's Lymphomas Start of enrollment: 2011 Aug 22
Completed
Phase 2
Zevalin-Containing Nonmyeloablative Conditioning for Stem Cell Transplantation (SCT) Start of enrollment: 2013 Jan 01
Completed
Phase 2
Lenalidomide and Ipilimumab After Stem Cell Transplant in Treating Patients With Hematologic or Lymphoid Malignancies Start of enrollment: 2013 Nov 04
Active, not recruiting
Phase 2
Carfilzomib Consolidation Therapy After Autologous Stem Cell Transplantation (ASCT) for Mantle Cell Lymphoma (MCL), T-cell Lymphoma (TCL), and Diffuse Large B-Cell Lymphoma (DLBCL) Start of enrollment: 2014 Jun 17
Completed
Phase 1
Inotuzumab Ozogamicin and Chemotherapy in Treating Patients With Leukemia or Lymphoma Undergoing Stem Cell Transplantation Start of enrollment: 2019 Oct 28
Recruiting
Phase 2
Bendamustine With or Without Cyclophosphamide in Preventing GVHD in Patients Undergoing Stem Cell Transplant Start of enrollment: 2020 Mar 13
Recruiting
Phase 1, Phase 2
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Publications & Presentations

PubMed

Incidence and risk factors of early onset VOD/SOS differ in younger vs older adults after stem cell transplantation.
Curtis Marcoux, Rima M Saliba, Whitney Wallis, Sajad Khazal, Dristhi Ragoonanan, Gabriela Rondon, Priti Tewari, Uday Popat, Betul Oran, Amanda Olson, Qaiser Bashir, Mu...> ;Blood Advances. 2024 Mar 12
Safety and long-term survival results of the addition of inotuzumab ozogamicin to the conditioning regimen of allogeneic stem cell transplantation: A single-center pha...
Issa F Khouri, Kamal Alzahrani, Hagop Kantarjian, Denái R Milton, Alison M Gulbis, Koji Sasaki, Nitin Jain, Nicholas J Short, Tapan Kadia, May Daher, Hind Rafei, Jin S...> ;American Journal of Hematology. 2024 May 1
Outcomes of toxoplasmosis after allogeneic hematopoietic stem cell transplantation and the role of antimicrobial prophylaxis.
Malek, A., Al-Juhaishi, T., Milton, D., Ramdial, J., Daher, M., Olson, A., Srour, S., Alatrash, G., Oran, B., Mehta, R., Khouri, I., Bashir, Q., Shah, N., Ciurea, S., ...> ;Bone Marrow Transplantation. 2024 Feb 14
1 citations
Myeloablative fractionated busulfan for allogeneic stem cell transplant in older patients or patients with comorbidities.
Uday R Popat, Oren Pasvolsky, Roland Bassett Jr, Rohtesh S Mehta, Amanda Olson, Julianne Chen, Amin M Alousi, Gheath Al-Atrash, Qaiser Bashir, Alison M Gulbis, Chitra ...> ;Blood Advances. 2023 Oct 24
Clinical relevance of MYC/BCL2 expression and cell of origin in patients with diffuse large b-cell lymphoma treated with autologous transplant.
Taha Al-Juhaishi, Yingjun Wang, Denái R Milton, Zijun Y Xu-Monette, Elias Jabbour, May Daher, Jin S Im, Qaiser Bashir, Swaminathan P Iyer, David Marin, Amanda L Olson,...> ;Bone Marrow Transplantation. 2023 Sep 1
7 citations
The outcomes of patients with chronic myeloid leukemia treated with third-line BCR::ABL1 tyrosine kinase inhibitors.
Elias J Jabbour, Koji Sasaki, Fadi G Haddad, Ghayas C Issa, Guillermo Garcia-Manero, Tapan M Kadia, Nitin Jain, Musa Yilmaz, Courtney D DiNardo, Keyur P Patel, Rashmi ...> ;American Journal of Hematology. 2023 Apr 1
15 citations
Frontline combination of ponatinib and hyper-CVAD in Philadelphia chromosome-positive acute lymphoblastic leukemia: 80-months follow-up results.
Hagop Kantarjian, Nicholas J Short, Nitin Jain, Koji Sasaki, Xuelin Huang, Fadi G Haddad, Issa Khouri, Courtney D DiNardo, Naveen Pemmaraju, William Wierda, Guillermo ...> ;American Journal of Hematology. 2023 Mar 1
2 citations
HLA Factors versus Non-HLA Factors for Haploidentical Donor Selection.
Rohtesh S Mehta, Kai Cao, Rima M Saliba, Gheath Al-Atrash, Amin M Alousi, Konstantinos Lontos, Curtis Marcoux, Yudith Carmazzi, Gabriela Rondon, Qaiser Bashir, Chitra ...> ;Transplantation and Cellular Therapy. 2023 Mar 1
18 citations
Post-Transplantation Cyclophosphamide Versus Tacrolimus and Methotrexate Graft-Versus-Host Disease Prophylaxis for HLA-Matched Donor Transplantation.
Rohtesh S Mehta, Rima M Saliba, Gabriela Rondon, Gheath Al-Atrash, Qaiser Bashir, Chitra M Hosing, Partow Kebriaei, Issa Khouri, Yago Nieto, Betul Oran, Uday R Popat, ...> ;Transplantation and Cellular Therapy. 2022 Oct 1
4 citations
Mycophenolate Mofetil: A Friend or a Foe with Post-Transplantation Cyclophosphamide and Tacrolimus Prophylaxis in HLA-Matched Donors?
Rohtesh S Mehta, Rima M Saliba, Eiko Hayase, Robert R Jenq, Susan Abraham, Asif Rashid, Gabriela Rondon, Gheath Al-Atrash, Qaiser Bashir, Chitra M Hosing, Partow Kebri...> ;Transplantation and Cellular Therapy. 2022 Aug 1
3 citations
Haploidentical versus Matched Unrelated versus Matched Sibling Donor Hematopoietic Cell Transplantation with Post-Transplantation Cyclophosphamide.
Rohtesh S Mehta, Rima M Saliba, Sassine Ghanem, Amin M Alousi, Gabriela Rondon, Paolo Anderlini, Gheath Al-Atrash, Qaiser Bashir, Chitra M Hosing, Jin S Im, Partow Keb...> ;Transplantation and Cellular Therapy. 2022 Jul 1
4 citations
Autologous stem cell transplantation for large B-cell lymphoma with secondary central nervous system involvement.
Serkan Akin, Chitra Hosing, Issa Khouri, Sairah Ahmed, Amin Alousi, Nathan Fowler, Jacinth Joseph, Jonathan Truxillo, Jeremy L Ramdial, Farzaneh Maadani, Gabriela Rond...> ;Blood Advances. 2022 Apr 12
1 citations
Clinical outcome of allogeneic stem cell transplantation in patients with B-cell lymphoid malignancies following treatment with targeted small molecule inhibitors.
Akash Mukherjee, Denái R Milton, Elias J Jabbour, Alison M Gulbis, Tapan Kadia, Nitin Jain, Celina Ledesma, Jan Burger, Alessandra Ferrajoli, William Wierda, L Jeffrey...> ;Leukemia & Lymphoma. 2022 Apr 1
26 citations
Blinatumomab maintenance after allogeneic hematopoietic cell transplantation for B-lineage acute lymphoblastic leukemia.
Mahmoud R Gaballa, Pinaki Banerjee, Denái R Milton, Xianli Jiang, Christina Ganesh, Sajad Khazal, Vandana Nandivada, Sanjida Islam, Mecit Kaplan, May Daher, Rafet Basa...> ;Blood. 2022 Mar 24
6 citations
Sleeping beauty generated CD19 CAR T-Cell therapy for advanced B-Cell hematological malignancies.
Harjeet Singh, Samer A Srour, Denái R Milton, Jessica McCarty, Cuiping Dai, Mahmoud R Gaballa, Mariam Ammari, Simon Olivares, Helen Huls, Eleanor De Groot, David Marin...> ;Frontiers in Immunology. 2022 Jan 1
17 citations
Allogeneic hematopoietic cell transplantation for patients with blastic plasmacytoid dendritic cell neoplasm (BPDCN).
Qaiser Bashir, Denái R. Milton, Uday R. Popat, Partow Kebriaei, Chitra Hosing, Issa F. Khouri, Katayoun Rezvani, Yago Nieto, Betul Oran, Samer A. Srour, Neeraj Saini, ...> ;Bone Marrow Transplantation. 2021 Oct 11
12 citations
Bone Marrow versus Peripheral Blood Grafts for Haploidentical Hematopoietic Cell Transplantation with Post-Transplantation Cyclophosphamide.
Rohtesh S. Mehta, Rima M. Saliba, Leonard C. Alsfeld, Jeffrey L. Jorgensen, Sa A. Wang, Paolo Anderlini, Gheath Alatrash, Qaiser Bashir, Stefan O. Ciurea, Chitra Hosin...> ;Transplantation and Cellular Therapy. 2021 Sep 16
2 citations
Nine-Year Follow-up of Patients with Relapsed Follicular Lymphoma after Nonmyeloablative Allogeneic Stem Cell Transplant and Autologous Transplant.
Issa F. Khouri, Denái R. Milton, Alison M. Gulbis, Elias Jabbour, Loretta J. Nastoupil, Celina Ledesma, Paolo Anderlini, Qaiser Bashir, May Daher, Jin S. Im, Swaminath...> ;Clinical Cancer Research. 2021 Aug 11
6 citations
Myeloablative Fractionated Busulfan With Fludarabine in Older Patients: Long Term Disease-Specific Outcomes of a Prospective Phase II Clinical Trial.
Rohtesh S. Mehta, Roland L. Bassett, Julianne Chen, Benigno C. Valdez, Jitesh D. Kawedia, Amin M. Alousi, Paolo Anderlini, Gheath Alatrash, Qaiser Bashir, Stefan O. Ci...> ;Transplantation and Cellular Therapy. 2021 Nov 1
9 citations
Hyper-CVAD plus ofatumumab versus hyper-CVAD plus rituximab as frontline therapy in adults with Philadelphia chromosome-negative acute lymphoblastic leukemia: A propen...
Koji Sasaki, Hagop M. Kantarjian, Kiyomi Morita, Nicholas J. Short, Marina Konopleva, Nitin Jain, Farhad Ravandi, Guillermo Garcia-Manero, Sa Wang, Joseph D. Khoury, J...> ;Cancer. 2021 Sep 15
14 citations
Eltrombopag for Post-Transplantation Thrombocytopenia: Results of Phase II Randomized, Double-Blind, Placebo-Controlled Trial.
Sairah Ahmed, Qaiser Bashir, Roland L. Bassett, Man Yin C. Poon, Ben C. Valdez, Sergej Konoplev, Amin M. Alousi, Borje S. Andersson, Stefan O. Ciurea, Chitra Hosing, R...> ;Transplantation and Cellular Therapy. 2021 May 1
19 citations
Third-Party BK Virus-Specific Cytotoxic T Lymphocyte Therapy for Hemorrhagic Cystitis Following Allotransplantation.
Amanda Olson, Ruitao Lin, David Marin, Hind Rafei, Mustafa Bdaiwi, Peter F. Thall, Rafet Basar, Ala Abudayyeh, Pinaki P. Banerjee, Fleur M. Aung, Indresh Kaur, Glorett...> ;Journal of Clinical Oncology. 2021 Apr 30
29 citations
Prognostic factors for progression in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia in complete molecular response within 3 months of the...
Koji Sasaki, Hagop M. Kantarjian, Nicholas J. Short, Bachar Samra, Joseph D. Khoury, Rashmi Kanagal Shamanna, Marina Konopleva, Nitin Jain, Courtney D. DiNardo, Rita K...> ;Cancer. 2021 Aug 1
4 citations
Outcomes in patients with CRLF2 overexpressed acute lymphoblastic leukemia after allogeneic hematopoietic cell transplantation.
Paul Koller, Rima M. Saliba, Celina Ledesma, Gabriela Rondon, Uday R. Popat, Amin M. Alousi, Rohtesh S. Mehta, Betul Oran, Amanda Olson, Chitra Hosing, Muzaffar H. Qaz...> ;Bone Marrow Transplantation. 2021 Mar 25
22 citations
Long-term follow-up of salvage therapy using a combination of inotuzumab ozogamicin and mini-hyper-CVD with or without blinatumomab in relapsed/refractory Philadelphia...
Elias Jabbour, Koji Sasaki, Nicholas J. Short, Farhad Ravandi, Xuelin Huang, Joseph D. Khoury, Rashmi Kanagal-Shamanna, Jeffrey L. Jorgensen, Issa F. Khouri, Partow Ke...> ;Cancer. 2021 Jun 15
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Journal Articles

Pilot Study Using Post-Transplant Cyclophosphamide (PTCy), Tacrolimus and Mycophenolate GVHD Prophylaxis for Older Patients Receiving 10/10 HLA-Matched Unrelated Donor...
Uday R Popat, Amin Alousi, Issa F Khouri, Muzaffar Qazilbash, Richard E Champlin, Partow Kebriaei, Simrit Parmar, Chitra Hosing, Nature
Impact of a Novel Prognostic Model, Hematopoietic Cell Transplant-Composite Risk (HCT-CR), on Allogeneic Transplant Outcomes in Patients with Acute Myeloid Leukemia an...
Uday Popat, Chitra M Hosing, Issa Khouri, Richard Champlin, Simrit Parmar, Partow Kebriaei, Borje S Andersson, Qaiser Bashir, Amin Alousi, Nature

Abstracts/Posters

Clinical Relevance of MYC/BCL2 and Cell of Origin in Patients with Relapsed Diffuse Large B-Cell Lymphoma Treated with Autologous Stem Cell Transplantation
Issa F. Khouri, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
Post-Transplant Cyclophosphamide (PT-Cy) Based Haploidentical Cell Transplantation (Haplo) Versus Rabbit Anti-Thymocyte Globulin (r-ATG) Based HLA Matched Unrelated Do...
Issa F. Khouri, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Comparative Review of 30 Day Non-Relapse Mortality (NRM) in B-Cell Lymphomas Associated with Anti-CD19 Chimeric Antigen Receptor T-Cells (CAR-T) from FDA Database, Cli...
Issa F. Khouri, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Allogeneic Hematopoietic Cell Transplantation May Improve Long-Term Outcomes in Patients with Ph-like Acute Lymphoblastic Leukemia with CRLF2 Overexpression
Issa F. Khouri, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Myeloablative Fractionated Busulfan Conditioning Regimen in Older Patients: Results of a Phase II Study
Issa F. Khouri, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
Reduced Severe aGVHD and Improved Survival Using Post Transplant Cyclophosphamide/Tacrolimus/Methotrexate Graft Versus Host Disease Prophylaxis in AML Patients Receivi...
Issa F. Khouri, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
A Randomized Study of Fludarabine-Clofarabine Vs Fludarabine Alone Combined with Busulfan and Allogeneic Hematopoietic Transplantation for AML and MDS
Issa F. Khouri, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
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Professional Memberships

American Society of Clinical Oncology - ASCO
Member

Hospital Affiliations

University of Texas M.D. Anderson Cancer CenterHouston, Texas

IssaF.KhouriMD

Dr. Khouri is on Doximity

Education & Training

Certifications & Licensure

Clinical Trials

Publications & Presentations

Professional Memberships

Hospital Affiliations

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