IvanLieberburgMD

PubMed

• Amyloid-related imaging abnormalities in patients with Alzheimer's disease treated with bapineuzumab: a retrospective analysis.
  Sperling R Salloway S Brooks DJ Tampieri D Barakos J Fox NC Raskind M Sabbagh M Honig LS Porsteinsson AP Lieberburg I Arrighi HM Morris KA Lu Y Liu E Gr...> ;Lancet Neurol. 2012 Mar
• 65 citations
  Lethality of Alzheimer disease and its impact on nursing home placement.
  Henry Michael Arrighi, Peter J. Neumann, Ivan Lieberburg, Raymond J. Townsend> ;Alzheimer Disease and Associated Disorders. 2010 Jan 1
• A phase 2 multiple ascending dose trial of bapineuzumab in mild to moderate Alzheimer disease.
  Salloway S Sperling R Gilman S Fox NC Blennow K Raskind M Sabbagh M Honig LS Doody R van Dyck CH Mulnard R Barakos J Gregg KM Liu E Lieberburg I Schenk ...> ;Neurology. 2009 Dec 15
• 686 citations
  Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain
  H. F. Dovey, V. John, J. P. Anderson, L. Z. Chen, P. De Saint Andrieu, L. Y. Fang, S. B. Freedman, B. Folmer, E. Goldbach, E. J. Holsztynska, K. L. Hu, K. L. Johnson-W...> ;Journal of Neurochemistry. 2009 Apr 22
• 1542 citations
  Peripherally administered antibodies against amyloid beta-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease.
  Frederique Bard, Catherine Cannon, Robin Barbour, Rae Lyn Burke, Dora Games, Henry Grajeda, Teresa Guido, Kang Hu, Jiping Huang, Kelly Johnson-Wood, Karen Khan, Dora K...> ;Nature Medicine. 2000 Aug 1
• 53 citations
  β-Peptide Immunization: A Possible New Treatment for Alzheimer Disease
  Dale Schenk, Peter Seubert, Ivan Lieberburg, Jan Wallace> ;Archives of Neurology. 2000 Jul 1
• 1289 citations
  Purification and cloning of amyloid precursor protein beta-secretase from human brain.
  Sukanto Sinha, John P. Anderson, Robin Barbour, Guriqbal S. Basi, Russell J. Caccavello, David Davis, Minhtam Doan, Harry F. Dovey, Normand Frigon, Jin Hong, Kirsten L...> ;Nature. 1999 Dec 2
• Cellular mechanisms of beta-amyloid production and secretion.
  Sinha S Lieberburg I> ;Proc Natl Acad Sci U S A. 1999 Sep 28
• 2355 citations
  Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse.
  Dale Schenk, Robin Barbour, Whitney Dunn, Grace Gordon, Henry Grajeda, Teresa Guido, Kang Hu, Jiping Huang, Kelly Johnson-Wood, Karen Khan, Dora Kholodenko, Michael K....> ;Nature. 1999 Jul 8
• High cerebrospinal fluid tau and low amyloid beta42 levels in the clinical diagnosis of Alzheimer disease and relation to apolipoprotein E genotype.
  Galasko D Chang L Motter R Clark CM Kaye J Knopman D Thomas R Kholodenko D Schenk D Lieberburg I Miller B Green R Basherad R Kertiles L Boss MA Seubert P> ;Arch Neurol. 1998 Jul
• 663 citations
  Estrogen Therapy in Postmenopausal Women: Effects on Cognitive Function and Dementia
  Kristine Yaffe, George F. Sawaya, Ivan Lieberburg, Deborah Grady> ;JAMA. 1998 Mar 4
• Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease.
  Johnson-Wood K Lee M Motter R Hu K Gordon G Barbour R Khan K Gordon M Tan H Games D Lieberburg I Schenk D Seubert P McConlogue L> ;Proc Natl Acad Sci U S A. 1997 Feb 18
• The regulatory Ser262 of microtubule-associated protein tau is phosphorylated by phosphorylase kinase.
  Paudel HK> ;J Biol Chem. 1997 Jan 17
• 1003 citations
  Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid β-protein in both transfected cells and transgenic mice
  Martin Citron, David Westaway, Weiming Xia, George A. Carlson, Thekla S. Diehl, G. Levesque, Kelly Johnson-Wood, Michael K. Lee, Peter Seubert, Angela Davis, Dora Khol...> ;Nature Medicine. 1997 Jan 1
• 73 citations
  Beta-secretase processing of the beta-amyloid precursor protein in transgenic mice is efficient in neurons but inefficient in astrocytes
  Jun Zhao, Lisa Paganini, Lennart Mucke, Marissa Gordon, Larry Refolo, Mark D. Carman, Sukanto Sinha, Tilman Oltersdorf, Ivan Lieberburg, Lisa McConlogue> ;The Journal of Biological Chemistry. 1996 Dec 6
• 1 citations
  The Effect of Apolipoprotein E Genotype on Biochemical Markers of Alzheimer's Disease
  Dale Schenk, Ivan Lieberburg, Ruth Motter, Peter Seubert> ;Annals of the New York Academy of Sciences. 1996 Dec 1
• Levels and alternative splicing of amyloid beta protein precursor (APP) transcripts in brains of APP transgenic mice and humans with Alzheimer's disease.
  Rockenstein EM McConlogue L Tan H Power M Masliah E Mucke L> ;J Biol Chem. 1995 Nov 24
• 103 citations
  Production and increased detection of amyloid β protein and amyloidogenic fragments in brain microvessels, meningeal vessels and choroid plexus in Alzheimer's disease
  Rajesh N. Kalaria, D. R. D. Premkumar, Andrea B. Pax, D. L. Cohen, Ivan Lieberburg> ;Brain Research. Molecular Brain Research. 1996 Jan 1
• 30 citations
  Amyloid β-peptide in cerebrospinal fluid in individuals with the Swedish Alzheimer amyloid precursor protein mutation
  Lars Lannfelt, Hans Basun, Carmen Vigo-Pelfrey, Lars-Olof Wahlund, Bengt Winblad, Ivan Lieberburg, Dale Schenk> ;Neuroscience Letters. 1995 Oct 27
• 59 citations
  Therapeutic approaches related to amyloid-beta peptide and Alzheimer's disease.
  Dale Schenk, Russell E. Rydel, Patrick J. C. May, Sheila P. Little, Jill Ann Panetta, Ivan Lieberburg, Sukanto Sinha> ;Journal of Medicinal Chemistry. 1995 Oct 1
• 508 citations
  Reduction of beta-amyloid peptide42 in the cerebrospinal fluid of patients with Alzheimer's disease.
  R. Motter, Carmen Vigo-Pelfrey, Dora Kholodenko, Robin Barbour, Kelly Johnson-Wood, Doug R. Galasko, Linda Chang, Bruce L. Miller, C. Clark, Robert C. Green, D. Olson,...> ;Annals of Neurology. 1995 Oct 1
• Chronic elevation of secreted amyloid precursor protein in subcortically lesioned rats, and its exacerbation in aged rats.
  Wallace WC Lieberburg I Schenk D Vigo-Pelfrey C Davis KL Haroutunian V> ;J Neurosci. 1995 Jul
• 297 citations
  Detection of phosphorylated Ser262 in fetal tau, adult tau, and paired helical filament tau.
  Peter Seubert, Madhumalti Mawal-Dewan, Robin Barbour, Ross Jakes, Michel Goedert, Gail V.W. Johnson, Joel M. Litersky, Dale Schenk, Ivan Lieberburg, John Q. Trojanowsk...> ;The Journal of Biological Chemistry. 1995 Aug 11
• 92 citations
  Cerebrospinal fluid levels of amyloid β‐protein in alzheimer's disease: Inverse correlation with severity of dementia and effect of apolipoprotein e genotype
  Roger Nitsch, G. William Rebeck, Meihua Deng, U. Ingrid Richardson, Marsha Tennis, Dale Schenk, Carmen Vigo-Pelfrey, Ivan Lieberburg, Richard J. Wurtman, Bradley T. Hy...> ;Annals of Neurology. 1995 Apr 1
• 164 citations
  Elevation of microtubule-associated protein tau in the cerebrospinal fluid of patients with Alzheimer's disease.
  Carmen Vigo-Pelfrey, P.PhD Seubert, Robin Barbour, C. Blomquist, Michael K. Lee, D. Lee, F. Coria, Linda Chang, Bruce L. Miller, Ivan Lieberburg, Dale Schenk> ;Neurology. 1995 Apr 1
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