IvanOrlandoRosasMD

PubMed

• Proteomic Biomarkers of Quantitative Interstitial Abnormalities in COPDGene and CARDIA Lung Study.
  Choi, B., Liu, G., Sheng, Q., Amancherla, K., Perry, A., Huang, X., San José Estépar, R., Ash, S., Guan, W., Jacobs, D., Martinez, F., Rosas, I., Bowler, R., Kropski, ...> ;American Journal of Respiratory and Critical Care Medicine. 2024 Jan 29
• Spatial Transcriptomics Resolve an Emphysema-Specific Lymphoid Follicle B Cell Signature in Chronic Obstructive Pulmonary Disease.
  Joselyn Rojas-Quintero, Scott A Ochsner, Felicia New, Prajan Divakar, Chen Xi Yang, Tianshi David Wu, Jerid Robinson, Darshan Shimoga Chandrashekar, Nicholas E Banovic...> ;American Journal of Respiratory and Critical Care Medicine. 2024 Jan 1
• TRIOBP modulates β-catenin signaling by regulation of miR-29b in idiopathic pulmonary fibrosis.
  Wang, L., Zhao, W., Xia, C., Ma, S., Li, Z., Wang, N., Ding, L., Wang, Y., Cheng, L., Liu, H., Yang, J., Li, Y., Yu, G., Rosas, I.> ;Cellular and Molecular Life Sciences. 2023 Dec 29
• Unagi: Deep Generative Model for Deciphering Cellular Dynamics and In-Silico Drug Discovery in Complex Diseases.
  Zheng, Y., Schupp, J., Adams, T., Clair, G., Justet, A., Ahangari, F., Yan, X., Hansen, P., Carlon, M., Cortesi, E., Vermant, M., Vos, R., De Sadeleer, L., Rosas, I., ...> ;Research Square. 2023 Dec 18
• Tuftelin1 drives experimental pulmonary fibrosis progression by facilitating stress fiber assembly.
  Niu, C., Xu, K., Hu, Y., Jia, Y., Yang, Y., Pan, X., Wan, R., Lian, H., Wang, Q., Yang, J., Li, Y., Wang, L., Yu, G., Rosas, I.> ;Respiratory Research. 2023 Dec 17
• 1 citations
  Spatial Transcriptomics Resolve an Emphysema-specific Lymphoid Follicle B Cell Signature in COPD.
  Rojas-Quintero, J., Ochsner, S., New, F., Divakar, P., Yang, C., Wu, T., Robinson, J., Shimoga Chandrashekar, D., Banovich, N., Rosas, I., Sauler, M., Kheradmand, F., ...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Dec 8
• Short peripheral blood leukocyte telomere length in rheumatoid arthritis-interstitial lung disease.
  Doyle, T., Juge, P., Peljto, A., Lee, S., Walts, A., Esposito, A., Poli, S., Gill, R., Hatabu, H., Nishino, M., Dellaripa, P., Weinblatt, M., Shadick, N., Demoruelle, ...> ;Thorax. 2024 Jan 18
• 1 citations
  ACSS3 regulates the metabolic homeostasis of epithelial cells and alleviates pulmonary fibrosis.
  Lan Wang, Hongmei Yuan, Wenwen Li, Peishuo Yan, Mengxia Zhao, Zhongzheng Li, Huabin Zhao, Shenghui Wang, Ruyan Wan, Yajun Li, Juntang Yang, Xin Pan, Ivan Rosas, Guoyin...> ;Biochimica Et Biophysica Acta. Molecular Basis of Disease. 2024 Feb 1
• 3 citations
  Single-Cell RNA Sequencing Provides New Insights into Therapeutic Roles of Thyroid Hormone in Idiopathic Pulmonary Fibrosis.
  Lan Wang, Zhongzheng Li, Ruyan Wan, Xin Pan, Bin Li, Huabin Zhao, Juntang Yang, Weiming Zhao, Shenghui Wang, Qiwen Wang, Peishuo Yan, Chi Ma, Hongmei Yuan, Mengxia Zha...> ;American Journal of Respiratory Cell and Molecular Biology. 2023 Oct 1
• 6 citations
  Serum Proteomics Identifies Biomarkers Associated With the Pathogenesis of Idiopathic Pulmonary Fibrosis.
  Lan Wang, Minghui Zhu, Yan Li, Peishuo Yan, Zhongzheng Li, Xiuping Chen, Juntang Yang, Xin Pan, Huabin Zhao, Shenghui Wang, Hongmei Yuan, Mengxia Zhao, Xiaogang Sun, R...> ;Molecular & Cellular Proteomics. 2023 Apr 1
• Peptidylarginine deiminase 2 citrullinates MZB1 and promotes the secretion of IgM and IgA.
  Benjamin Geary, Bo Sun, Ronak R Tilvawala, Leonard Barasa, Konstantin Tsoyi, Ivan O Rosas, Paul R Thompson, I-Cheng Ho> ;Frontiers in Immunology. 2023 Jan 1
• 1 citations
  Lymphangioleiomyomatosis: circulating levels of FGF23 and pulmonary diffusion.
  Anthony J Esposito, Jewel Imani, Shikshya Shrestha, Shefali Bagwe, Anthony M Lamattina, Marina Vivero, Hilary J Goldberg, Ivan O Rosas, Elizabeth P Henske, Souheil Y E...> ;Jornal Brasileiro De Pneumologia. 2023 Jan 1
• 4 citations
  TRIB3 Mediates Fibroblast Activation and Fibrosis though Interaction with ATF4 in IPF.
  Lan Wang, Wenyu Zhao, Cong Xia, Zhongzheng Li, Weiming Zhao, Kai Xu, Ningdan Wang, Hui Lian, Ivan O Rosas, Guoying Yu> ;International Journal of Molecular Sciences. 2022 Dec 11
• 8 citations
  Fulminant lung fibrosis in non-resolvable COVID-19 requiring transplantation.
  Soma S K Jyothula, Andrew Peters, Yafen Liang, Weizhen Bi, Pooja Shivshankar, Simon Yau, Puneet S Garcha, Xiaoyi Yuan, Bindu Akkanti, Scott Collum, Nancy Wareing, Raja...> ;Ebiomedicine. 2022 Dec 1
• 4 citations
  Serum proteomic profiling of rheumatoid arthritis-interstitial lung disease with a comparison to idiopathic pulmonary fibrosis.
  Kim, E. Y., Xiaoping Wu, Yunju Jeong, Sergio Poli de Frías, Imaani Easthausen, Katherine Hoffman, Clara Oromendia, Shahrad Taheri, Anthony J Esposito, Luisa Quesada Ar...> ;Thorax. 2022 Oct 1
• 11 citations
  Vasculopathy and Increased Vascular Congestion in Fatal COVID-19 and Acute Respiratory Distress Syndrome.
  Julian A Villalba, Caroline F Hilburn, Michelle A Garlin, Grant A Elliott, Yijia Li, Keiko Kunitoki, Sergio Poli, George A Alba, Emilio Madrigal, Manuel Taso, Melissa ...> ;American Journal of Respiratory and Critical Care Medicine. 2022 Oct 1
• 6 citations
  Systemic sclerosis associated interstitial lung disease: a conceptual framework for subclinical, clinical and progressive disease.
  David Roofeh, Kevin K Brown, Ella A Kazerooni, Donald Tashkin, Shervin Assassi, Fernando Martinez, Athol U Wells, Ganesh Raghu, Christopher P Denton, Lorinda Chung, An...> ;Rheumatology. 2023 May 2
• 2 citations
  Progressive Interstitial Lung Disease in Relatives of Patients with Pulmonary Fibrosis.
  Jonathan A Rose, Maria A Planchart Ferretto, Anthony H Maeda, Maria F Perez Garcia, Nikkola E Carmichael, Swati Gulati, Mary B Rice, Hilary J Goldberg, Rachel K Putman...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Jan 15
• 16 citations
  Understanding post-COVID-19 interstitial lung disease (ILD): a new fibroinflammatory disease entity.
  Puja Mehta, Ivan O Rosas, Mervyn Singer> ;Intensive Care Medicine. 2022 Dec 1
• 40 citations
  Safety, tolerability, and efficacy of pirfenidone in patients with rheumatoid arthritis-associated interstitial lung disease: a randomised, double-blind, placebo-contr...
  Joshua J Solomon, Sonye K Danoff, Felix A Woodhead, Shelley Hurwitz, Rie Maurer, Ian Glaspole, Paul F Dellaripa, Bibek Gooptu, Robert Vassallo, P Gerard Cox, Kevin R F...> ;The Lancet. Respiratory Medicine. 2023 Jan 1
• 18 citations
  Saracatinib, a Selective Src Kinase Inhibitor, Blocks Fibrotic Responses in Preclinical Models of Pulmonary Fibrosis.
  Farida Ahangari, Christine Becker, Daniel G Foster, Maurizio Chioccioli, Meghan Nelson, Keriann Beke, Xing Wang, Aurelien Justet, Taylor Adams, Benjamin Readhead, Carl...> ;American Journal of Respiratory and Critical Care Medicine. 2022 Dec 15
• 5 citations
  Suspected Interstitial Lung Disease in COPDGene Study.
  Jonathan A Rose, Aravind A Menon, Takuya Hino, Akinori Hata, Mizuki Nishino, David A Lynch, Ivan O Rosas, Souheil El-Chemaly, Benjamin A Raby, Samuel Y Ash, Bina Choi,...> ;American Journal of Respiratory and Critical Care Medicine. 2023 Jan 1
• 2 citations
  Screening for preclinical parenchymal lung disease in rheumatoid arthritis.
  Anthony J Esposito, Jeffrey A Sparks, Ritu R Gill, Hiroto Hatabu, Eric J Schmidlin, Partha V Hota, Sergio Poli, Elaine A Fletcher, Wesley Xiong, Michelle L Frits, Chri...> ;Rheumatology. 2022 Aug 3
• 3 citations
  Quantitative Interstitial Abnormality Progression and Outcomes in the Genetic Epidemiology of COPD and Pittsburgh Lung Screening Study Cohorts.
  Bina Choi, Najma Adan, Tracy J Doyle, Ruben San José Estépar, Rola Harmouche, Stephen M Humphries, Matthew Moll, Michael H Cho, Rachel K Putman, Gary M Hunninghake, Ra...> ;Chest. 2023 Jan 1
• 12 citations
  A Phase IIb Randomized Clinical Study of an Anti-αβMonoclonal Antibody in Idiopathic Pulmonary Fibrosis.
  Ganesh Raghu, Majd Mouded, Daniel C Chambers, Fernando J Martinez, Luca Richeldi, Lisa H Lancaster, Mark J Hamblin, Kevin F Gibson, Ivan O Rosas, Antje Prasse, Guolin ...> ;American Journal of Respiratory and Critical Care Medicine. 2022 Nov 1
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Journal Articles

• Tocilizumab in Hospitalized Patients with Severe Covid-19 Pneumonia  
  Ivan O Rosas, Ronaldo C Go, Ivor S Douglas, Larry Tsai, Atul Malhotra, The New England Journal of Medicine
• MUC5B Promoter Variant and Rheumatoid Arthritis with Interstitial Lung Disease  
  Jay H Ryu, Deborah Assayag, Marvin I Schwarz, Paul Wolters, Andrew Gross, Ivan O Rosas, The New England Journal of Medicine