JaakkoLappalainenMD

PubMed

• Effect of fasedienol (PH94B) pherine nasal spray and steroidal hormones on electrogram responses and autonomic nervous system activity in healthy adult volunteers.
  Monti, L., Hanover, R., Salmán, E., Baker, R., Smith, M., Lappalainen, J.> ;Human Psychopharmacology. 2024 Mar 1
• 18 citations
  GABAA receptor occupancy by subtype selective GABAAα2,3 modulators: PET studies in humans
  Aurelija Jucaite, Zsolt Cselényi, Jaakko Lappalainen, Dennis J. McCarthy, Chi-Ming Lee, Svante Nyberg, Katarina Varnäs, Per Stenkrona, Christer Halldin, Alan J. Cross,...> ;Psychopharmacology. 2017 Feb 1
• 36 citations
  Alcohol and mortality after moderate to severe traumatic brain injury: a meta-analysis of observational studies
  Rahul Raj, Era D. Mikkonen, Jari Siironen, Juha Hernesniemi, Jaakko Lappalainen, Markus B. Skrifvars> ;Journal of Neurosurgery. 2016 Jun 1
• 39 citations
  Acute alcohol intoxication and long-term outcome in patients with traumatic brain injury.
  Rahul Raj, Markus B. Skrifvars, Riku Kivisaari, Juha Hernesniemi, Jaakko Lappalainen, Jari Siironen> ;Journal of Neurotrauma. 2015 Jan 13
• 21 citations
  Randomized clinical trial of disulfiram for cocaine dependence or abuse during buprenorphine treatment.
  Richard S. Schottenfeld, Marek C. Chawarski, Joseph F. Cubells, Tony P. George, Jaakko Lappalainen, Thomas R. Kosten> ;Drug and Alcohol Dependence. 2014 Mar 1
• 36 citations
  Factors correlating with delayed trauma center admission following traumatic brain injury
  Rahul Raj, Jari Siironen, Riku Kivisaari, Markku Kuisma, Tuomas Brinck, Jaakko Lappalainen, Markus B. Skrifvars> ;Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine. 2013 Sep 10
• 12 citations
  Health-related quality of life and cost-effectiveness of treatment in subarachnoid haemorrhage.
  Kirsi Malmivaara, Seppo Juvela, Juha Hernesniemi, Jaakko Lappalainen, Jari Siironen> ;European Journal of Neurology. 2012 Nov 1
• 76 citations
  Pharmacogenetic randomized trial for cocaine abuse: disulfiram and dopamine β-hydroxylase.
  Thomas R. Kosten, Guiying Wu, Wen Huang, Mark J. Harding, Sara C. Hamon, Jaakko Lappalainen, David A. Nielsen> ;Biological Psychiatry. 2013 Feb 1
• A sequencing‐based survey of functional APAF1 alleles in a large sample of individuals with affective illness and population controls
  Zenab Amin, Katarzyna Kanarek, Evgeny Krupitsky, Espen Walderhaug, Risto Ilomäki, Hilary P. Blumberg, Lawrence H. Price, Zubin Bhagwagar, Linda L. Carpenter, Audrey R....> ;American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics. 2009 May 19
• 28 citations
  Apolipoprotein E genotype and outcome after aneurysmal subarachnoid hemorrhage: Clinical article
  Seppo Juvela, Jari Siironen, Jaakko Lappalainen> ;Journal of Neurosurgery. 2009 May 1
• 7 citations
  Population admixture modulates risk for alcohol dependence.
  Lingjun Zuo, Xingguang Luo, Jennifer B. Listman, Henry R. Kranzler, Shuang Wang, Raymond F. Anton, Hilary P. Blumberg, Murray B. Stein, Godfrey D. Pearlson, Jonathan C...> ;Human Genetics. 2009 Mar 22
• 22 citations
  Twenty-one-base-pair insertion polymorphism creates an enhancer element and potentiates SLC6A1 GABA transporter promoter activity.
  Rungnapa Hirunsatit, Elizabeth D. George, Barbara K. Lipska, Hani M. Elwafi, Lisa C. Sander, Carolyn M. Yrigollen, Joel Gelernter, Elena L. Grigorenko, Jaakko Lappalai...> ;Pharmacogenetics and Genomics. 2009 Jan 1
• 28 citations
  RELATIONSHIP OF THE MET ALLELE OF THE BRAIN-DERIVED NEUROTROPHIC FACTOR VAL66MET POLYMORPHISM TO MEMORY AFTER ANEURYSMAL SUBARACHNOID HEMORRHAGE
  Juhani Vilkki, Jaakko Lappalainen, Seppo Juvela, Katarzyna Kanarek, Juha Hernesniemi, Jari Siironen> ;Neurosurgery. 2008 Aug 1
• 20 citations
  Temporal association of onset of daily smoking with adolescent substance use and psychiatric morbidity
  Risto Ilomäki, Kaisa Riala, Helinä Hakko, Jaakko Lappalainen, Taru Ollinen, Pirkko Räsänen, Markku Timonen> ;European Psychiatry. 2008 Mar 1
• 4 citations
  Sequence variation and linkage disequilibrium in the GABA transporter-1 gene (SLC6A1) in five populations: implications for pharmacogenetic research
  Rungnapa Hirunsatit, Risto Ilomäki, Robert T. Malison, Pirkko Räsänen, Essi Ilomäki, Henry R. Kranzler, Thomas R. Kosten, Atapol Sughondhabirom, Nuntika Thavichachart,...> ;BMC Genetics. 2007 Oct 17
• 94 citations
  The Met Allele of the BDNF Val66Met Polymorphism Predicts Poor Outcome Among Survivors of Aneurysmal Subarachnoid Hemorrhage
  Jari Siironen, Seppo Juvela, Katarzyna Kanarek, Juhani Vilkki, Juha Hernesniemi, Jaakko Lappalainen> ;Stroke. 2007 Oct 1
• 96 citations
  Interactive effects of sex and 5-HTTLPR on mood and impulsivity during tryptophan depletion in healthy people.
  Espen Walderhaug, Andres Magnusson, Alexander Neumeister, Jaakko Lappalainen, Hilde Lunde, Helge Refsum, Nils Inge Landrø> ;Biological Psychiatry. 2007 Sep 15
• 41 citations
  Dopamine β-Hydroxylase Gene (DβH) -1021C→T Influences Self-Reported Paranoia during Cocaine Self-Administration
  Rasmon Kalayasiri, Atapol Sughondhabirom, Ralitza Gueorguieva, Vladimir Coric, Wendy J. Lynch, Jaakko Lappalainen, Joel Gelernter, Joseph F. Cubells, Robert T. Malison> ;Biological Psychiatry. 2007 Jun 1
• 21 citations
  Mutation screen of the GAD2 gene and association study of alcoholism in three populations
  Jaakko Lappalainen, Evgeny Krupitsky, Henry R. Kranzler, Xingguang Luo, Mikhail Remizov, Sofia Pchelina, A E Taraskina, Edwin Zvartau, Pirkko Räsänen, Taru Mäkikyrö, L...> ;American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics. 2007 Mar 5
• 128 citations
  γ-Aminobutyric acid type A receptors and alcoholism: Intoxication, dependence, vulnerability, and treatment
  John H. Krystal, Julie K. Staley, Graeme F. Mason, Ismene L. Petrakis, Joan Kaufman, R. Adron Harris, Joel Gelernter, Jaakko Lappalainen> ;Archives of General Psychiatry. 2006 Sep 1
• 226 citations
  Brain derived neurotrophic factor (BDNF) gene variants and Alzheimer's disease, affective disorders, posttraumatic stress disorder, schizophrenia, and substance depend...
  Huiping Zhang, Fatih Ozbay, Jaakko Lappalainen, Henry R. Kranzler, Christopher H. van Dyck, Dennis S. Charney, Lawrence H. Price, Steven M. Southwick, Bao-Zhu Yang, An...> ;American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics. 2006 Jun 5
• 128 citations
  Association between two μ-opioid receptor gene (OPRM1) haplotype blocks and drug or alcohol dependence
  Huiping Zhang, Xingguang Luo, Henry R. Kranzler, Jaakko Lappalainen, Bao-Zhu Yang, Evgeny Krupitsky, Edwin Zvartau, Joel Gelernter> ;Human Molecular Genetics. 2006 Mar 15
• 8 citations
  Nicotine use and dependence and their association to psychiatric disorders in a large sample of adolescent psychiatric inpatients
  Helinä Hakko, Janne Lintunen, Jaakko Lappalainen, Taru Mäkikyrö, Pirkko Räsänen, Markku Timonen> ;Addictive Behaviors. 2006 Oct 1
• 76 citations
  ADH4 gene variation is associated with alcohol and drug dependence: results from family controlled and population-structured association studies.
  Xingguang Luo, Henry R. Kranzler, Lingjun Zuo, Bao-Zhu Yang, Jaakko Lappalainen, Joel Gelernter> ;Pharmacogenetics and Genomics. 2005 Nov 1
• 87 citations
  ADH4 Gene Variation is Associated with Alcohol Dependence and Drug Dependence in European Americans: Results from HWD Tests and Case–Control Association Studies
  Xingguang Luo, Henry R. Kranzler, Lingjun Zuo, Jaakko Lappalainen, Bao-Zhu Yang, Joel Gelernter> ;Neuropsychopharmacology. 2006 May 1
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