Jack T Stapleton MD
Professor, Internal Medicine, Microbiology and Immunology, University of Iowa College of Medicine
Join to View Full Profile
200 Hawkins DrIowa City, IA 52242
Phone+1 319-356-3168
Fax+1 319-356-4600
Dr. Stapleton is on Doximity
As a Doximity member you'll join over two million verified healthcare professionals in a private, secure network.
- Gain access to free telehealth tools, such as our “call shielding” and one-way patient texting.
- Connect with colleagues in the same hospital or clinic.
- Read the latest clinical news, personalized to your specialty.
Education & Training
University of North Carolina HospitalsFellowship, Infectious Disease, 1983 - 1986- University of North Carolina HospitalsResidency, Internal Medicine, 1980 - 1983
University of Kansas School of MedicineClass of 1980
Certifications & Licensure
IA State Medical License 1986 - 2027
NC State Medical License 1982 - 1999
American Board of Internal Medicine Internal Medicine- American Board of Internal Medicine Infectious Disease
Awards, Honors, & Recognition
- Regional Top Doctor Castle Connolly, 2022
Clinical Trials
- TIV and High Dose TIV in Subjects With Rheumatoid Arthritis Start of enrollment: 2011 Oct 01
- Randomized, Open-label Phase II Trial to Assess the Safety and Immunogenicity of MVA-BN Smallpox Vaccine in Immunocompromised Subjects With HIV Infection Start of enrollment: 2014 Apr 28
Publications & Presentations
PubMed
- The hidden threat: HBV reactivation in the era of antiretroviral therapy optimization.Pere Domingo, Jack T Stapleton
AIDS. 2026-01-01 - Extracellular condensates (ECs) are endogenous modulators of HIV transcription and latency reactivation.Wasifa Naushad, Lakmini S Premadasa, Vyshnavi Tallapaneni, Bryson C Okeoma, Ashok Chaudhary
Molecular Psychiatry. 2025-11-29 - Characterization of Serotype-Specific Dengue Virus T-Cell Inhibition.Jinhua Xiang, James H McLinden, Qing Chang, Micaela Fosdick, Hillel Haim
The Journal of Infectious Diseases. 2025-11-14
Journal Articles
- Semen Exosomes Promote Transcriptional Silencing of HIV-1 by Disrupting NF-kB/Sp1/Tat CircuitryJack Stapleton, MD, mBio
Press Mentions
‘No One Believed That It Would Ever Come to This Place’: Fear and Hatred Clouded Efforts to Care for Iowa’s Early AIDS PatientsMay 16th, 2023- Modified Vaccinia Ankara Vaccine Efficacious for Smallpox Protection in Phase 3 StudyNovember 14th, 2019
Grant Support
- SARS CoV-2 Immune Evasion MechanismsIOWA CITY VA MEDICAL CENTER2009–2026
- Research Training in Infectious DiseasesUNIVERSITY OF IOWA1988–2025
- GBV-C Effects On CD4 Activation And ExpansionNational Institute Of Allergy And Infectious Diseases2009–2011
- GB Virus Type C Natural History, Epidemiology, HIV InteractionNational Institute Of Allergy And Infectious Diseases2007–2008
- Smallpox Vaccination On Endothelial Function And Human Gene ExpressionNational Center For Research Resources2005–2006
Viewing the full profile is available to verified healthcare professionals only.
Find your profile and take control of your online presence:
