JacobStuartBowersMD

PubMed

• 24 citations
  Identification of human CD4+ T cell populations with distinct antitumor activity.
  Michelle H. Nelson, Hannah M. Knochelmann, Stefanie R. Bailey, Logan W. Huff, Jacob S. Bowers, Kinga Majchrzak, Megan M. Wyatt, Mark P. Rubinstein, Shikhar Mehrotra, M...> ;Science Advances. 2020 Jul 1
• 15 citations
  IL6 Fuels Durable Memory for Th17 Cell-Mediated Responses to Tumors.
  Hannah M. Knochelmann, Connor J. Dwyer, Aubrey S. Smith, Jacob S. Bowers, Megan M. Wyatt, Michelle H. Nelson, Guillermo Rangel RIvera, Joshua D. Horton, Carsten Krieg,...> ;Cancer Research. 2020 Jun 19
• 8 citations
  Genomics meets immunity in pancreatic cancer: Current research and future directions for pancreatic adenocarcinoma immunotherapy.
  Jacob S. Bowers, Stefanie R. Bailey, Mark P. Rubinstein, Chrystal M. Paulos, E. Ramsay Camp> ;Oncology Reviews. 2019 Aug 1
• 63 citations
  Human CD26 high T cells elicit tumor immunity against multiple malignancies via enhanced migration and persistence
  Stefanie R. Bailey, Michelle H. Nelson, Kinga Majchrzak, Jacob S. Bowers, Megan M. Wyatt, Aubrey S. Smith, Lillian R. Neal, Keisuke Shirai, Carmine Carpenito, Carl H. ...> ;Nature Communications. 2017 Dec 6
• 23 citations
  Adoptive Transfer of Ceramide Synthase 6 Deficient Splenocytes Reduces the Development of Colitis
  Matthew J. Scheffel, Kristi L. Helke, Ping Lu, Jacob S. Bowers, Besim Ogretmen, Elizabeth Garrett-Mayer, Chrystal M. Paulos, Christina Voelkel-Johnson> ;Scientific Reports. 2017 Nov 14
• 40 citations
  PI3Kδ Inhibition Enhances the Antitumor Fitness of Adoptively Transferred CD8 + T Cells.
  Jacob S. Bowers, Kinga Majchrzak, Michelle H. Nelson, Bulent Arman Aksoy, Megan M. Wyatt, Aubrey S. Smith, Stefanie R. Bailey, Lillian R. Neal, Jeff Hammerbacher, Chry...> ;Frontiers in Immunology. 2017 Sep 29
• 29 citations
  β-catenin and PI3Kδ inhibition expands precursor Th17 cells with heightened stemness and antitumor activity.
  Kinga Majchrzak, Michelle H. Nelson, Jacob S. Bowers, Stefanie R. Bailey, Megan M. Wyatt, John Wrangle, Mark P. Rubinstein, Juan C. Varela, Zihai Li, Richard A. Himes,...> ;JCI Insight. 2017 Apr 20
• 185 citations
  Resident memory T cells in the skin mediate durable immunity to melanoma.
  Brian T. Malik, Katelyn T. Byrne, Jennifer L. Vella, Peisheng Zhang, Tamer B. Shabaneh, Shannon M. Steinberg, Aleksey K. Molodtsov, Jacob S. Bowers, Christina V. Angel...> ;Science Immunology. 2017 Apr 14
• 46 citations
  Th17 cells are refractory to senescence and retain robust antitumor activity after long-term ex vivo expansion
  Jacob S. Bowers, Michelle H. Nelson, Kinga Majchrzak, Stefanie R. Bailey, Baerbel Rohrer, Andrew Kaiser, Carl Atkinson, Luca Gattinoni, Chrystal M. Paulos> ;JCI Insight. 2017 Mar 9
• 4 citations
  Murine Th17 cells utilize IL-2 receptor gamma chain cytokines but are resistant to cytokine withdrawal-induced apoptosis
  Daniel J. Neitzke, Jacob S. Bowers, Kristina Andrijauskaite, Nathaniel O'Connell, Elizabeth Garrett-Mayer, John Wrangle, Zihai Li, Chrystal M. Paulos, David J. Cole, M...> ;Cancer Immunology, Immunotherapy. 2017 Mar 9
• 31 citations
  The Basics of Artificial Antigen Presenting Cells in T Cell-Based Cancer Immunotherapies.
  Lillian R. Neal, Bailey, Megan M. Wyatt, Jacob S. Bowers, Kinga Majchrzak, Michelle H. Nelson, Carl Haupt, Chrystal M. Paulos, Juan C. Varela> ;Journal of Immunology Research and Therapy. 2017 Jun 26
• 19 citations
  Toll-like receptor agonist therapy can profoundly augment the antitumor activity of adoptively transferred CD8(+) T cells without host preconditioning.
  Michelle H. Nelson, Jacob S. Bowers, Stefanie R. Bailey, Marshall A. Diven, Caroline W. Fugle, Andrew Kaiser, Claudia Wrzesinski, Bei Liu, Nicholas P. Restifo, Chrysta...> ;Journal for Immunotherapy of Cancer. 2016 Feb 16
• 31 citations
  Exploiting IL-17-producing CD4+ and CD8+ T cells to improve cancer immunotherapy in the clinic.
  Kinga Majchrzak, Michelle H. Nelson, Stefanie R. Bailey, Jacob S. Bowers, Xue-Zhong Yu, Mark P. Rubinstein, Richard A. Himes, Chrystal M. Paulos> ;Cancer Immunology, Immunotherapy. 2016 Jan 29
• 23 citations
  Dendritic Cells in Irradiated Mice Trigger the Functional Plasticity and Antitumor Activity of Adoptively Transferred Tc17 Cells via IL12 Signaling
  Jacob S. Bowers, Michelle H. Nelson, Sreenath Kundimi, Stefanie R. Bailey, Logan W. Huff, Kristina M. Schwartz, David J. Cole, Mark P. Rubinstein, Chrystal M. Paulos> ;Clinical Cancer Research. 2015 Jun 1
• 31 citations
  The Inducible Costimulator Augments Tc17 Cell Responses to Self and Tumor Tissue
  Michelle H. Nelson, Sreenath Kundimi, Jacob S. Bowers, Carolyn E. Rogers, Logan W. Huff, Kristina M. Schwartz, Krishnamurthy Thyagarajan, Elizabeth C. Little, Shikhar ...> ;Journal of Immunology. 2015 Feb 15
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