JacobSamuelBrennerMD

PubMed

• Anaerobic Lactate Production Is Associated With Decreased Microcirculatory Blood Flow and Decreased Mitochondrial Respiration Following Cardiovascular Surgery With Car...
  Fatima M Talebi, Frances S Shofer, Vladimir R Muzykantov, Jan Bakker, John C Greenwood, David H Jang, Audrey E Spelde, Emily K Gordon, Jiri Horak, Michael A Acker, Tod...> ;Critical Care Medicine. 2024 Apr 5
• Controlling spatial distribution of functional lipids in a supported lipid bilayer prepared from vesicles.
  Hyun-Su Lee, Ye Chan Kim, Zhicheng Wang, Vladimir R Muzykantov, Jacob W Myerson, Russell J Composto, Jacob S Brenner> ;Journal of Colloid and Interface Science. 2024 Jun 15
• 1 citations
  Targeting lipid nanoparticles to the blood-brain barrier to ameliorate acute ischemic stroke.
  Jia Nong, Patrick M Glassman, Vladimir V Shuvaev, Sahily Reyes-Esteves, Helene C Descamps, Raisa Y Kiseleva, Tyler E Papp, Mohamad-Gabriel Alameh, Ying K Tam, Barbara ...> ;Molecular Therapy. 2024 Mar 7
• Automated measurement of distance-walked as a "sixth vital sign" for detecting infusion reactions during preclinical testing.
  Liam S Chase, Michael H Zaleski, Lianne J Morrell, Jacob S Brenner> ;International Journal of Pharmaceutics. 2023 Oct 15
• Low postoperative perfused vessel density is associated with increased soluble endothelial cell adhesion molecules during circulatory shock after cardiac surgery.
  John C Greenwood, Fatima M Talebi, David H Jang, Audrey E Spelde, Emily K Gordon, Jiri Horak, Michael A Acker, Todd J Kilbaugh, Frances S Shofer, John G T Augoustides,...> ;Microvascular Research. 2023 Nov 1
• 1 citations
  Meta-analysis of material properties influencing nanoparticle plasma pharmacokinetics.
  Briana Macedo, Manthan Patel, Michael H Zaleski, Parth Mody, Xiaonan Ma, Patrick Mei, Jacob W Myerson, Jacob S Brenner, Patrick M Glassman> ;International Journal of Pharmaceutics. 2023 May 25
• 7 citations
  Mechanisms by Which Liposomes Improve Inhaled Drug Delivery for Alveolar Diseases.
  Laura T Ferguson, Xiaonan Ma, Jacob W Myerson, Jichuan Wu, Patrick M Glassman, Marco E Zamora, Elizabeth D Hood, Michael Zaleski, Mengwen Shen, Eno-Obong Essien, Vladi...> ;Advanced Nanobiomed Research. 2023 Mar 1
• 4 citations
  Targeted drug delivery to the brain endothelium dominates over passive delivery via vascular leak in experimental intracerebral hemorrhage.
  Sahily Reyes-Esteves, Jia Nong, Patrick M Glassman, Serena Omo-Lamai, Sarah Ohashi, Jacob W Myerson, Marco E Zamora, Xiaonan Ma, Scott E Kasner, Lauren Sansing, Vladim...> ;Journal of Controlled Release. 2023 Apr 1
• 6 citations
  Topical nitroglycerin to detect reversible microcirculatory dysfunction in patients with circulatory shock after cardiovascular surgery: an observational study.
  John C Greenwood, Fatima M Talebi, David H Jang, Audrey E Spelde, Joseph E Tonna, Jacob T Gutsche, Jiri Horak, Michael A Acker, Todd J Kilbaugh, Frances S Shofer, John...> ;Scientific Reports. 2022 Sep 10
• 42 citations
  Added to pre-existing inflammation, mRNA-lipid nanoparticles induce inflammation exacerbation (IE).
  Hamideh Parhiz, Jacob S Brenner, Priyal N Patel, Tyler E Papp, Hamna Shahnawaz, Qin Li, Ruiqi Shi, Marco E Zamora, Amir Yadegari, Oscar A Marcos-Contreras, Ambika Nate...> ;Journal of Controlled Release. 2022 Apr 1
• 5 citations
  Protocol for the MicroRESUS study: The impact of circulatory shock and resuscitation on microcirculatory function and mitochondrial respiration after cardiovascular su...
  John C Greenwood, Fatima M Talebi, David H Jang, Audrey E Spelde, Todd J Kilbaugh, Frances S Shofer, Michael A Acker, John G T Augoustides, Jan Bakker, Nuala J Meyer, ...> ;Plos One. 2022 Jan 1
• 40 citations
  Supramolecular arrangement of protein in nanoparticle structures predicts nanoparticle tropism for neutrophils in acute lung inflammation.
  Jacob W. Myerson, Priyal Patel, Kathryn M Rubey, Marco E Zamora, Michael H Zaleski, Nahal Habibi, Landis R. Walsh, Yi-Wei Lee, David C. Luther, Laura T. Ferguson, Osca...> ;Nature Nanotechnology. 2021 Nov 18
• 10 citations
  Wearable biosensors have the potential to monitor physiological changes associated with opioid overdose among people who use drugs: A proof-of-concept study in a real-...
  Alexis M. Roth, Nguyen Khoi Tran, Ben Cocchiaro, Allison K. Mitchell, David G. Schwartz, Devon J. Hensel, Janna Ataiants, Jacob S. Brenner, Inbal Yahav, Stephen E. Lan...> ;Drug and Alcohol Dependence. 2021 Oct 28
• 19 citations
  Nanomedicine to fight infectious disease.
  Kathryn M. Rubey, Jacob S. Brenner> ;Advanced Drug Delivery Reviews. 2021 Oct 8
• 38 citations
  Red blood cells: The metamorphosis of a neglected carrier into the natural mothership for artificial nanocarriers.
  Patrick M. Glassman, Elizabeth D. Hood, Laura T. Ferguson, Zongmin Zhao, Don L. Siegel, Samir Mitragotri, Jacob S. Brenner, Vladimir R. Muzykantov> ;Advanced Drug Delivery Reviews. 2021 Nov 1
• 7 citations
  The Nano-War Against Complement Proteins
  Zhicheng Wang, Jacob S. Brenner> ;The AAPS Journal. 2021 Sep 10
• 49 citations
  Red Blood Cell Hitchhiking: A Novel Approach for Vascular Delivery of Nanocarriers
  Jacob S. Brenner, Samir Mitragotri, Vladimir R. Muzykantov> ;Annual Review of Biomedical Engineering. 2021 Jul 13
• 14 citations
  COVID-19 and the Early-Career Physician-Scientist. Fostering Resilience beyond the Pandemic
  Corrine R. Kliment, Ian J. Barbash, Jacob S. Brenner, Divay Chandra, Katherine R. Courtright, Marc Gauthier, Keven M. Robinson, Leslie P. Scheunemann, Faraaz Ali Shah,...> ;ATS Scholar. 2021 Mar 1
• 12 citations
  Willingness to use a wearable device capable of detecting and reversing overdose among people who use opioids in Philadelphia.
  Katie Kanter, Ryan Gallagher, Feyisope R. Eweje, Alexander Lee, David Gordon, Stephen Landy, Julia Gasior, Haideliza Soto-Calderon, Peter F. Cronholm, Ben Cocchiaro, J...> ;Harm Reduction Journal. 2021 Jul 23
• 6 citations
  Monoclonal antibody 2C5 specifically targets neutrophil extracellular traps.
  Lívia Palmerston Mendes, Kobra Rostamizadeh, Kandace Gollomp, Jacob W Myerson, Oscar A Marcos-Contreras, Marco Zamora, Ed Luther, Jacob S. Brenner, Nina Filipczak, Xia...> ;Mabs. 2020 Dec 15
• 51 citations
  Targeting drug delivery in the vascular system: Focus on endothelium.
  Patrick M. Glassman, Jacob W. Myerson, Laura T. Ferguson, Raisa Yu Kiseleva, Vladimir V. Shuvaev, Jacob S. Brenner, Vladimir R. Muzykantov> ;Advanced Drug Delivery Reviews. 2020 Jun 21
• 61 citations
  Vascular drug delivery using carrier red blood cells: Focus on RBC surface loading and pharmacokinetics
  Patrick M. Glassman, Carlos H. Villa, Anvay Ukidve, Zongmin Zhao, Paige N. Smith, Samir Mitragotri, Alan J. Russell, Jacob S. Brenner, Vladimir R. Muzykantov> ;Pharmaceutics. 2020 May 9
• 84 citations
  Selective targeting of nanomedicine to inflamed cerebral vasculature to enhance the blood–brain barrier
  Oscar A. Marcos-Contreras, Colin F. Greineder, Raisa Yu Kiseleva, Hamideh Parhiz, Landis R. Walsh, Viviana Zuluaga-Ramirez, Jacob W. Myerson, Elizabeth D. Hood, Carlos...> ;Proceedings of the National Academy of Sciences of the United States of America. 2020 Jan 31
• 30 citations
  Combining vascular targeting and the local first pass provides 100-fold higher uptake of ICAM-1-targeted vs untargeted nanocarriers in the inflamed brain.
  Oscar A. Marcos-Contreras, Jacob S. Brenner, Raisa Yu Kiseleva, Viviana Zuluaga-Ramirez, Colin F. Greineder, Carlos H. Villa, Elizabeth D. Hood, Jacob W. Myerson, Silv...> ;Journal of Controlled Release. 2019 May 10
• 5 citations
  Using selective lung injury to improve murine models of spatially heterogeneous lung diseases
  Andrew J. Paris, Lei Guo, Ning Dai, Jeremy Katzen, Priyal Patel, G. Scott Worthen, Jacob S. Brenner> ;Plos One. 2019 Apr 3
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