JacobM.MishellMD

Adult Congenital Heart Disease, Interventional Cardiology

Interventional Cardiologist Medical Director, Kaiser Permanente Northern California Transcatheter Valve and Structural Heart Program Assistant Clinical Professor of Medicine, University of California, San Francisco

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Office
2238 Geary Blvd
San Francisco, CA 94115
Phone+1 415-833-2000
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Education & Training

University of California (San Francisco)Fellowship, Interventional Cardiology, 2004 - 2005
University of California (San Francisco)Fellowship, Cardiovascular Disease, 2000 - 2004
Johns Hopkins UniversityResidency, Internal Medicine, 1997 - 2000
University of Rochester School of Medicine and DentistryClass of 1997

Certifications & Licensure

CA State Medical License 2000 - 2025
MD State Medical License 2001 - 2003
American Board of Internal Medicine Cardiovascular Disease
American Board of Internal Medicine Interventional Cardiology

Clinical Trials

Cardiovascular Outcomes Assessment of the MitraClip Percutaneous Therapy for Heart Failure Patients With Functional Mitral Regurgitation (The COAPT Trial) and COAPT CAS Start of enrollment: 2012 Aug 01
Active, not recruiting
Not Applicable

Publications & Presentations

PubMed

1 citations
Eligibility and Potential Benefit of Transcatheter Edge-to-Edge Repair in a Contemporary Cohort With Heart Failure: Evidence From a Large Integrated Health Care Delive...
Andrew P Ambrosy, Jingrong Yang, Andrew S Tai, Sadia J Dimbil, Elisha A Garcia, Sue Hee Sung, Ankeet S Bhatt, Matthew D Solomon, Ivy A Ku, Jacob M Mishell, Edward J Mc...> ;Structural Heart. 2024 Mar 1
1 citations
Physician assessment of aortic stenosis severity, quantitative parameters, and long-term outcomes: Results from the KP-VALVE project.
Matthew D Solomon, Grace Tabada, Sue Hee Sung, Amanda Allen, Jacob M Mishell, Andrew N Rassi, Edward McNulty, Femi Philip, David C Lange, Andrew P Ambrosy, Jonathan G ...> ;American Heart Journal. 2023 Dec 1
1 citations
Incidence, Predictors, and Outcomes Associated With Worsening Renal Function in Patients With Heart Failure and Secondary Mitral Regurgitation: The COAPT Trial.
Jeremy Kong, Jonathan G Zaroff, Andrew P Ambrosy, Jesse K Fitzpatrick, Ivy A Ku, Jacob M Mishell, Lak N Kotinkaduwa, Björn Redfors, Nirat Beohar, Gorav Ailawadi, JoAnn...> ;Journal of the American Heart Association. 2023 Jul 18
Outcomes of Adults with Severe Aortic Stenosis Undergoing Urgent or Emergent vs. Elective Transcatheter Aortic Valve Replacement Within an Integrated Health Care Deliv...
Andrew P Ambrosy, Thomas K Leong, Sue Hee Sung, Elisha A Garcia, Ivy A Ku, Matthew D Solomon, Edward J McNulty, Andrew N Rassi, David C Lange, Femi Philip, Alan S Go, ...> ;Structural Heart. 2023 Jul 1
1 citations
Cerebrovascular Events After Transcatheter Edge-to-Edge Repair and Guideline-Directed Medical Therapy in the COAPT Trial.
Flavien Vincent, Björn Redfors, Lak N Kotinkaduwa, Saibal Kar, D Scott Lim, Jacob M Mishell, Brian K Whisenant, JoAnn Lindenfeld, William T Abraham, Michael J Mack, Gr...> ;JACC. Cardiovascular Interventions. 2023 Jun 26
1 citations
Temporal trends in the prevalence and severity of aortic stenosis within a contemporary and diverse community-based cohort.
Andrew P Ambrosy, Alan S Go, Thomas K Leong, Elisha A Garcia, Alex J Chang, Edward J McNulty, Jacob M Mishell, Andrew N Rassi, Ivy A Ku, David C Lange, Femi Philip, Be...> ;International Journal of Cardiology. 2023 Aug 1
44 citations
Five-Year Follow-up after Transcatheter Repair of Secondary Mitral Regurgitation.
Gregg W Stone, William T Abraham, JoAnn Lindenfeld, Saibal Kar, Paul A Grayburn, D Scott Lim, Jacob M Mishell, Brian Whisenant, Michael Rinaldi, Samir R Kapadia, Vivek...> ;The New England Journal of Medicine. 2023 Jun 1
6 citations
Association between serum albumin and outcomes in heart failure and secondary mitral regurgitation: the COAPT trial.
Kent Y Feng, Andrew P Ambrosy, Zhipeng Zhou, Ditian Li, Jeremy Kong, Jonathan G Zaroff, Jacob M Mishell, Ivy A Ku, Augustin Coisne, Björn Redfors, Michael J Mack, Will...> ;European Journal of Heart Failure. 2023 Apr 1
Predicting short-term outcomes after transcatheter aortic valve replacement for aortic stenosis.
Samuel T Savitz, Thomas Leong, Sue Hee Sung, Dalane W Kitzman, Edward McNulty, Jacob Mishell, Andrew Rassi, Andrew P Ambrosy, Alan S Go> ;American Heart Journal. 2023 Feb 1
21 citations
Prediction of Death or HF Hospitalization in Patients With Severe FMR: The COAPT Risk Score.
Neeraj Shah, Mahesh V Madhavan, William A Gray, Sorin J Brener, Yousif Ahmad, JoAnn Lindenfeld, William T Abraham, Paul A Grayburn, Saibal Kar, D Scott Lim, Jacob M Mi...> ;JACC. Cardiovascular Interventions. 2022 Oct 10
7 citations
Impact of baseline renal dysfunction on cardiac outcomes and end-stage renal disease in heart failure patients with mitral regurgitation: the COAPT trial.
Nirat Beohar, Gorav Ailawadi, Lak N Kotinkaduwa, Björn Redfors, Matheus Simonato, Zixuan Zhang, Loren Garrison Morgan, Esteban Escolar, Saibal Kar, David Scott Lim, Ja...> ;European Heart Journal. 2022 May 1
36 citations
Relationship Between Residual Mitral Regurgitation and Clinical and Quality-of-Life Outcomes After Transcatheter and Medical Treatments in Heart Failure: COAPT Trial.
Saibal Kar, Michael J. Mack, JoAnn Lindenfeld, William T. Abraham, Federico M. Asch, Neil J. Weissman, Maurice Enriquez-Sarano, D. Scott Lim, Jacob M. Mishell, Brian W...> ;Circulation. 2021 Aug 10
98 citations
3-Year Outcomes of Transcatheter Mitral Valve Repair in Patients With Heart Failure
Michael J. Mack, JoAnn Lindenfeld, William T. Abraham, Saibal Kar, D. Scott Lim, Jacob M. Mishell, Brian Whisenant, Paul A. Grayburn, Michael Rinaldi, Samir R. Kapadia...> ;Journal of the American College of Cardiology. 2021 Mar 2
11 citations
Outcomes of transcatheter mitral valve repair for secondary mitral regurgitation by severity of left ventricular dysfunction
Stamatios Lerakis, Annapoorna Kini, Federico M. Asch, Saibal Kar, D. Scott Lim, Jacob M. Mishell, Brian Whisenant, Paul A. Grayburn, Neil J. Weissman, Michael Rinaldi,...> ;Eurointervention. 2021 Jul 20
13 citations
Transcatheter Mitral Valve Repair in Patients With and Without Cardiac Resynchronization Therapy: The COAPT Trial.
Ioanna Kosmidou, JoAnn Lindenfeld, William T. Abraham, Saibal Kar, D. Scott Lim, Jacob M. Mishell, Brian Whisenant, Robert Kipperman, Konstantinos Dean Boudoulas, Björ...> ;Circulation. Heart Failure. 2020 Nov 12
10 citations
Baseline Functional Capacity and Transcatheter Mitral Valve Repair in Heart Failure With Secondary Mitral Regurgitation.
Umar I. Malik, Andrew P. Ambrosy, Ivy A. Ku, Jacob M. Mishell, Saibal Kar, D. Scott Lim, Brian Whisenant, David J. Cohen, Suzanne V. Arnold, Lak N. Kotinkaduwa, JoAnn ...> ;JACC. Cardiovascular Interventions. 2020 Oct 26
28 citations
Predictors of Clinical Response to Transcatheter Reduction of Secondary Mitral Regurgitation: The COAPT Trial.
Paul A. Grayburn, Anna Sannino, David J. Cohen, Saibal Kar, D. Scott Lim, Jacob M. Mishell, Brian Whisenant, Michael Rinaldi, Samir R. Kapadia, Vivek Rajagopal, Aaron ...> ;Journal of the American College of Cardiology. 2020 Sep 1
124 citations
Echocardiographic Outcomes After Transcatheter Leaflet Approximation in Patients With Secondary Mitral Regurgitation: The COAPT Trial.
Federico M. Asch, Paul A. Grayburn, Robert J. Siegel, Saibal Kar, D. Scott Lim, Jonathan G. Zaroff, Jacob M. Mishell, Brian Whisenant, Michael J. Mack, JoAnn Lindenfel...> ;Journal of the American College of Cardiology. 2019 Dec 17
70 citations
Health Status After Transcatheter Mitral-Valve Repair in Heart Failure and Secondary Mitral Regurgitation: COAPT Trial.
Suzanne V. Arnold, Khaja Chinnakondepalli, John A. Spertus, Elizabeth A. Magnuson, Suzanne J. Baron, Saibal Kar, D. Scott Lim, Jacob M. Mishell, William T. Abraham, Jo...> ;Journal of the American College of Cardiology. 2019 May 7
435 citations
Transcatheter Mitral-Valve Repair in Patients with Heart Failure.
Gregg W Stone, JoAnn Lindenfeld, William T Abraham, Saibal Kar, D Scott Lim, Jacob M Mishell, Brian Whisenant, Paul A Grayburn, Michael Rinaldi, Samir R Kapadia, Vivek...> ;The New England Journal of Medicine. 2018 Dec 13
43 citations
Determination of adequate coronary stent expansion using StentBoost, a novel fluoroscopic image processing technique
Jacob Mishell, Kalpesh T. Vakharia, Thomas A. Ports, Yerem Yeghiazarians, Andrew D. Michaels> ;Catheterization and Cardiovascular Interventions. 2007 Jan 1
32 citations
Randomized study of the safety and clinical utility of rotational vs. standard coronary angiography using a flat-panel detector.
Mateen Akhtar, Kalpesh T. Vakharia, Jacob Mishell, Atul Gera, Thomas A. Ports, Yerem Yeghiazarians, Andrew D. Michaels> ;Catheterization and Cardiovascular Interventions. 2005 Sep 1
31 citations
Akinetic myocardial infarcts must contain contracting myocytes: finite-element model study.
Alan B.C. Dang, Julius M. Guccione, Jacob M. Mishell, Peng Zhang, Arthur W. Wallace, Robert C. Gorman, Joseph H. Gorman, Mark B. Ratcliffe> ;American Journal of Physiology. Heart and Circulatory Physiology. 2005 Apr 1
1 citations
Effects of enhanced external counterpulsation on hemodynamics and its mechanism: relation to neurohumoral factors.
Jacob Mishell, Andrew Michaels> ;Circulation Journal. 2005 Jan 20
13 citations
Cases from the Osler Medical Service at Johns Hopkins University: cardiac valvular lesions in Wegener's granulamatosis.
Jacob M. Mishell> ;The American Journal of Medicine. 2002 Nov 1
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Hospital Affiliations

Kaiser Permanente San Francisco Medical CenterSan Francisco, California
Kaiser Permanente San Rafael Medical CenterSan Rafael, California
UCSF Medical CenterSan Francisco, California