JamesBarrAmesMD

Orthopaedic Surgery • Lebanon, NH

Orthopedic Sports Medicine

Assistant Professor, Orthopaedics, Geisel School of Medicine

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Office
1 Medical Center Dr
Dhmc Department Of Orthopedics
Lebanon, NH 03756
Phone+1 603-650-5155
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Education & Training

Steadman Philippon Research InstituteFellowship, Orthopaedic Sports Medicine, 2010 - 2011
Dartmouth-Hitchcock/Mary Hitchcock Memorial HospitalResidency, Orthopaedic Surgery, 2004 - 2010
Geisel School of Medicine at DartmouthClass of 2004

Certifications & Licensure

NH State Medical License 2009 - 2025
VT State Medical License 2008 - 2024
CO State Medical License 2010 - 2013
American Board of Orthopaedic Surgery Orthopaedic Surgery
American Board of Orthopaedic Surgery Orthopaedic Sports Medicine

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013

Publications & Presentations

PubMed

3 citations
Chemical shift assignments of a calmodulin intermediate with two Ca 2+ bound in complex with the IQ-motif of voltage-gated Ca 2+ channels (Ca V 1.2)
Ian Salveson, David E. Anderson, Johannes W. Hell, James B. Ames> ;Biomolecular NMR Assignments. 2019 Feb 20
10 citations
Retinal degeneration 3 (RD3) protein, a retinal guanylyl cyclase regulator, forms a monomeric and elongated four-helix bundle
Igor V. Peshenko, Qinhong Yu, Sunghyuk Lim, Diana Cudia, Alexander M. Dizhoor, James B. Ames> ;The Journal of Biological Chemistry. 2019 Feb 15
2 citations
Chemical shift assignments of retinal guanylyl cyclase activating protein 5 (GCAP5)
Diana Cudia, James B. Ames> ;Biomolecular NMR Assignments. 2019 Jan 31
14 citations
Dimerization of Neuronal Calcium Sensor Proteins
James B. Ames> ;Frontiers in Molecular Neuroscience. 2018 Nov 2
23 citations
Retinal guanylyl cyclase activating protein 1 forms a functional dimer.
Sunghyuk Lim, Graham Roseman, Igor V. Peshenko, Grace Manchala, Diana Cudia, Alexander M. Dizhoor, Glenn L. Millhauser, James B. Ames> ;Plos One. 2018 Mar 7
43 citations
α-Actinin Anchors PSD-95 at Postsynaptic Sites
Lucas Matt, Karam Kim, Anne C. Hergarden, Tommaso Patriarchi, Zulfiqar A. Malik, Deborah K. Park, Dhrubajyoti Chowdhury, Olivia R. Buonarati, Peter B. Henderson, Çiğde...> ;Neuron. 2018 Mar 7
1 citations
Detection of femoroplasty on pre- and post-arthroscopic comparison radiographs following treatment of femoroacetabular impingement syndrome: multi-reader accuracy and ...
Steffen J Haider, Alan Siegel, Kevin F. Spratt, James B Ames, J Allen Graham, Yvonne Y. Cheung> ;Skeletal Radiology. 2018 Feb 1
2 citations
Chemical shift assignments of retinal degeneration 3 protein (RD3).
Sunghyuk Lim, Diana Cudia, Qinhong Yu, Igor V. Peshenko, Alexander M. Dizhoor, James B. Ames> ;Biomolecular NMR Assignments. 2018 Jan 11
5 citations
Use of minimally invasive spine surgical instruments for the treatment of bone tumors.
Russell A. Reeves, Matthew C DeWolf, Peter J Shaughnessy, James B Ames, Eric Henderson> ;Expert Review of Medical Devices. 2017 Oct 4
4 citations
1H, 15N, and 13C chemical shift assignments of cyanobacteriochrome NpR6012g4 in the red-absorbing dark state.
Qinhong Yu, Sunghyuk Lim, Nathan Clarke Rockwell, Shelley S. Martin, J. Clark Lagarias, James B. Ames> ;Biomolecular NMR Assignments. 2016 Apr 1
4 citations
1H, 13C, and 15N chemical shift assignments of cyanobacteriochrome NpR6012g4 in the green-absorbing photoproduct state.
Sunghyuk Lim, Qinhong Yu, Nathan C. Rockwell, Shelley S. Martin, J. Clark Lagarias, James B. Ames> ;Biomolecular NMR Assignments. 2016 Apr 1
22 citations
Structure of Guanylyl Cyclase Activator Protein 1 (GCAP1) Mutant V77E in a Ca2+-free/Mg2+-bound Activator State.
Sunghyuk Lim, Igor V. Peshenko, Elena V. Olshevskaya, Alexander M. Dizhoor, James B. Ames> ;The Journal of Biological Chemistry. 2016 Feb 26
2 citations
Chemical shift assignments of the C-terminal EF-hand domain of α-actinin-1.
Matthew Turner, David E. Anderson, Sahana Rajan, Johannes W. Hell, James B. Ames> ;Biomolecular NMR Assignments. 2016 Feb 10
31 citations
Optimization of RGD-containing cyclic peptides against αvβ3 integrin
Yan Wang, Wenwu Xiao, Yonghong Zhang, Leah Meza, Harry Tseng, Yoshikazu Takada, James B. Ames, Kit S. Lam> ;Molecular Cancer Therapeutics. 2016 Feb 1
2 citations
Chemical shift assignments of mouse HOXD13 DNA binding domain bound to duplex DNA
Matthew Turner, Yonghong Zhang, Hanqian L. Carlson, H. Scott Stadler, James B. Ames> ;Biomolecular NMR Assignments. 2015 Oct 1
24 citations
Synthesis and Evaluation of Quinazolines as Inhibitors of the Bacterial Cell Division Protein FtsZ.
Gabriella M. Nepomuceno, Katie M. Chan, Valerie Huynh, Kevin S. Martin, Jared T. Moore, Terrence E. O’Brien, Luiz A. E. Pollo, Francisco J. Sarabia, Clarissa Tadeus, Z...> ;ACS Medicinal Chemistry Letters. 2015 Jan 21
11 citations
Structural Insights into Activation of the Retinal L-type Ca2+ Channel (Cav1.4) by Ca2+-binding Protein 4 (CaBP4)
Saebomi Park, Congmin Li, Françoise Haeseleer, Krzysztof Palczewski, James B. Ames> ;The Journal of Biological Chemistry. 2014 Nov 7
2 citations
1H, 15N, and 13C chemical shift assignments of murine calcium-binding protein 4
Saebomi Park, Congmin Li, James B. Ames> ;Biomolecular NMR Assignments. 2014 Oct 1
8 citations
¹H, ¹⁵N, and ¹³C chemical shift assignments of cyanobacteriochrome NpF2164g3 in the photoproduct state.
Sunghyuk Lim, Nathan C. Rockwell, Shelley S. Martin, J. Clark Lagarias, James B. Ames> ;Biomolecular NMR Assignments. 2014 Oct 1
57 citations
Capping of the N‐terminus of PSD‐95 by calmodulin triggers its postsynaptic release
Yonghong Zhang, Lucas Matt, Tommaso Patriarchi, Zulfiqar A. Malik, Dhrubajyoti Chowdhury, Deborah K. Park, Alessandra Renieri, James B. Ames, Johannes W. Hell> ;The EMBO Journal. 2014 Jun 17
28 citations
Photoconversion changes bilin chromophore conjugation and protein secondary structure in the violet/orange cyanobacteriochrome NpF2163g3
Sunghyuk Lim, Nathan C. Rockwell, Shelley S. Martin, Jerry L. Dallas, J. Clark Lagarias, James B. Ames> ;Photochemical & Photobiological Sciences. 2014 May 21
29 citations
Identification of Target Binding Site in Photoreceptor Guanylyl Cyclase Activating Protein 1 (GCAP1)
Igor V. Peshenko, Elena V. Olshevskaya, Sunghyuk Lim, James B. Ames, Alexander M. Dizhoor> ;The Journal of Biological Chemistry. 2014 Apr 4
1 citations
1H, 13C, and 15N Chemical Shift Assignments of Neuronal Calcium Sensor Protein, Hippocalcin
Congmin Li, James B. Ames> ;Biomolecular NMR Assignments. 2014 Apr 1
31 citations
Structural diversity of neuronal calcium sensor proteins and insights for activation of retinal guanylyl cyclase by GCAP1.
Sunghyuk Lim, Alexander M. Dizhoor, James B. Ames> ;Frontiers in Molecular Neuroscience. 2014 Mar 17
18 citations
Structural insights for activation of retinal guanylate cyclase by GCAP1.
Sunghyuk Lim, Igor V. Peshenko, Alexander M. Dizhoor, James B. Ames> ;Plos One. 2013 Nov 13
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Journal Articles

Correlating Structural and Photochemical Heterogeneity in Cyanobacteriochrome NpR6012g4
James Ames, MD, Proceedings of the National Academy of Sciences

Grant Support

Membrane-Targeting Calcium Sensors In VisionNational Eye Institute2006–2012
Membrane Targeting Calcium Sensors In VisionNational Eye Institute2009–2011
Structure And Function Of Neuronal Calcium Binding Proteins (CABPS)National Institute Of Neurological Disorders And Stroke2008–2011
Structure Of Dream A Calcium Sensor In Pain ControlNational Institute Of Neurological Disorders And Stroke2006–2007
Structure Of Dream A Calcium Sensor In Pain ControlNational Institute Of Neurological Disorders And Stroke2004–2006
Membrane-Targeting Calcium Sensors In VisionNational Eye Institute2004–2005
Membrane Targeting Calcium Sensors In VisionNational Eye Institute1999–2003
Molecular Mechanism Of Visual Recovery, Light AdaptationNational Eye Institute1994
Molecular Mechanism Of Visual Recovery And Light-AdaptatNational Eye Institute1992–1993