JamesD.AnholmMD

Pulmonology • Loma Linda, CA

Critical Care Medicine, Pleural Disease

Associate Professor, Medicine, Loma Linda University School of Medicine

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Office
11201 Benton St
111p
Loma Linda, CA 92357
Phone+1 909-583-6098
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Education & Training

University of Texas Southwestern Medical CenterFellowship, Pulmonary Disease and Critical Care Medicine, 1983 - 1985
Loma Linda University Health Education ConsortiumFellowship, Pulmonary Disease and Critical Care Medicine, 1982 - 1983
Loma Linda University Health Education ConsortiumResidency, Internal Medicine, 1980 - 1981
Adventist Health White MemorialInternship, Internal Medicine, 1977 - 1978
Loma Linda University School of MedicineClass of 1976

Certifications & Licensure

CA State Medical License 1979 - 2024
TX State Medical License 1984 - 1986
WI State Medical License 1978 - 1983
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Pulmonary Disease

Clinical Trials

Effect of Bosentan on Exercise Capacity at High Altitude Start of enrollment: 2006 Jul 01
Completed
Phase 1
Effect of Statin Therapy on C-reactive Protein Levels in Patients With Chronic Obstructive Lung Disease (COPD) Start of enrollment: 2008 Apr 01
Completed
Phase 1
Effects of Iloprost on Hypoxic Pulmonary Vasoconstriction and Exercise Capacity at High Altitude Start of enrollment: 2008 Jul 01
Unknown status
Phase 1
Effects of Iloprost on Hypoxic Pulmonary Vasoconstriction at Altitude Start of enrollment: 2008 Jul 01
Withdrawn
Phase 1
Multi-center Evaluation of the NEMO Gauge to Aid in Correct Positioning of the Endotracheal Tube Start of enrollment: 2016 Aug 15
Completed
Not Applicable
Effects of Naltrexone on Nocturnal Breathing Patterns at Altitude Start of enrollment: 2021 Aug 08
Completed
Phase 4
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

A narrative review of periodic breathing during sleep at high altitude: From acclimatizing lowlanders to adapted highlanders.
Alexander Patrician, Philip N Ainslie, James D Anholm> ;The Journal of Physiology. 2024 Mar 27
Effects of Dronabinol on Dyspnea and Quality of Life in Patients With COPD.
Abdul H Zaid, Suman B Thapamagar, James D Anholm, Laura Weaver-Carnahan, Lien Duong, Lennard Specht> ;Chronic Obstructive Pulmonary Diseases. 2024 Mar 26
Hemorheological, cardiorespiratory, and cerebrovascular effects of pentoxifylline following acclimatization to 3,800 m.
Steele, A., Howe, C., Gibbons, T., Foster, K., Williams, A., Caldwell, H., Brewster, L., Duffy, J., Monteleone, J., Stembridge, M., Ainslie, P., Tremblay, J., Subedi, ...> ;American Journal of Physiology. Heart and Circulatory Physiology. 2024 Mar 1
Manipulation of iron status on cerebral blood flow at high altitude in lowlanders and adapted highlanders.
Alexander Patrician, Christopher Willie, Ryan L Hoiland, Christopher Gasho, Prajan Subedi, James D Anholm, Michael M Tymko, Philip N Ainslie> ;Journal of Cerebral Blood Flow and Metabolism. 2023 Jul 1
3 citations
Pulmonary vascular reactivity to supplemental oxygen in Sherpa and lowlanders during gradual ascent to high altitude.
Prajan Subedi, Christopher Gasho, Michael Stembridge, Alexandra M Williams, Alexander Patrician, Philip N Ainslie, James D Anholm> ;Experimental Physiology. 2023 Jan 1
1 citations
Global REACH 2018: Characterizing Acid-Base Balance Over 21 Days at 4,300 m in Lowlanders.
Andrew R Steele, Philip N Ainslie, Rachel Stone, Kaitlyn Tymko, Courtney Tymko, Connor A Howe, David MacLeod, James D Anholm, Christopher Gasho, Michael M Tymko> ;High Altitude Medicine & Biology. 2022 Jun 1
3 citations
Acid-base balance at high altitude in lowlanders and indigenous highlanders.
Michael M Tymko, Christopher K Willie, Connor A Howe, Ryan L Hoiland, Rachel M Stone, Kaitlyn Tymko, Courtney Tymko, David MacLeod, James D Anholm, Christopher Gasho, ...> ;Journal of Applied Physiology. 2022 Feb 1
2 citations
Development and Evaluation of a Small Airway Disease Index Derived From Modeling the Late-Expiratory Flattening of the Flow-Volume Loop.
Hengji Chen, Sangeeta Joshi, Amber J Oberle, An-Kwok Wong, David Shaz, Suman Thapamagar, Laren Tan, James D Anholm, Paresh C Giri, Craig Henriquez, Yuh-Chin T Huang> ;Frontiers in Physiology. 2022 Jan 1
4 citations
GLOBAL REACH 2018: Iron infusion at high altitude reduces hypoxic pulmonary vasoconstriction equally in both lowlanders and healthy Andean highlanders
Alexander Patrician, Tony G. Dawkins, Geoff B. Coombs, Benjamin S. Stacey, Christopher Gasho, Travis D. Gibbons, Connor A. Howe, Joshua C. Tremblay, Rachel Stone, Kait...> ;Chest. 2021 Sep 8
8 citations
Global REACH 2018: the adaptive phenotype to life with chronic mountain sickness and polycythaemia
Alexander B. Hansen, Gilbert Moralez, Sachin B. Amin, Lydia L. Simspon, Florian Hofstaetter, James D. Anholm, Christopher Gasho, Mike Stembridge, Tony G. Dawkins, Mich...> ;The Journal of Physiology. 2021 Sep 1
5 citations
The influence of hemoconcentration on hypoxic pulmonary vasoconstriction in acute, prolonged and life-long hypoxemia.
Mike Stembridge, Ryan L. Hoiland, Alexandra M. Williams, Connor A. Howe, Joseph Donnelly, Tony G. Dawkins, Aimee L. Drane, Michael M. Tymko, Christopher Gasho, James D...> ;American Journal of Physiology. Heart and Circulatory Physiology. 2021 Aug 27
1 citations
Impact of pulmonary rehabilitation in sleep in COPD patients measured by actigraphy
Suman Thapamagar, Kathleen Ellstrom, James D. Anholm, R. Fargo, Nagamani Dandamudi> ;Plos One. 2021 Mar 16
14 citations
Influence of iron manipulation on hypoxic pulmonary vasoconstriction and pulmonary reactivity during ascent and acclimatization to 5050 m
Christopher K. Willie, Alexander Patrician, Ryan L. Hoiland, Alexandra M. Williams, Christopher Gasho, Prajan Subedi, James D. Anholm, Aimee L. Drane, Michael M. Tymko...> ;The Journal of Physiology. 2021 Jan 14
16 citations
The 2018 Global Research Expedition on Altitude Related Chronic Health (Global REACH) to Cerro de Pasco, Peru: an Experimental Overview
Michael M. Tymko, Ryan L. Hoiland, Joshua C. Tremblay, Mike Stembridge, Tony G. Dawkins, Geoff B. Coombs, Alexander Patrician, Connor A. Howe, Travis D. Gibbons, Jonat...> ;Experimental Physiology. 2021 Jan 1
10 citations
Generalized Approach to Translating Exercise Tests and Prescribing Exercise.
Carl Foster, James D. Anholm, Daniel Bok, Daniel Boullosa, Giancarlo Condello, Cristina Cortis, Andrea Fusco, Salvador J Jaime, Jos J. de Koning, Alejandro Lucia, John...> ;Journal of Functional Morphology and Kinesiology. 2020 Aug 12
Response to Limper et al. re: "Positional Changes in Arterial Oxygen Saturation and End-Tidal Carbon Dioxide at High Altitude: Medex 2015".
James D. Anholm, Arlena Kuenzel> ;High Altitude Medicine & Biology. 2020 Sep 8
5 citations
Positional Changes in Arterial Oxygen Saturation and End-Tidal Carbon Dioxide at High Altitude: Medex 2015.
Arlena Kuenzel, Ben Marshall, Samuel Verges, James D. Anholm> ;High Altitude Medicine & Biology. 2020 Jan 27
16 citations
Evidence for a physiological role of pulmonary arterial baroreceptors in sympathetic neural activation in healthy humans
Lydia L. Simpson, Victoria L Meah, Andrew R. Steele, Suman Thapamagar, Christopher Gasho, James D. Anholm, Aimee L. Drane, Tony G. Dawkins, Stephen A. Busch, Samuel J....> ;The Journal of Physiology. 2020 Mar 1
5 citations
Left Ventricular Twist Is Augmented in Hypoxia by β 1 -Adrenergic-Dependent and β 1 -Adrenergic-Independent Factors, Without Evidence of Endocardial Dysfunction.
Alexandra M. Williams, Philip N. Ainslie, James D. Anholm, Chris Gasho, Prajan Subedi, Mike Stembridge> ;Circulation. Cardiovascular Imaging. 2019 May 1
31 citations
The independent effects of hypovolaemia and pulmonary vasoconstriction on ventricular function and exercise capacity during acclimatisation to 3800 m.
Mike Stembridge, Philip N. Ainslie, Lindsey M. Boulet, James D. Anholm, Prajan Subedi, Michael M. Tymko, Christopher K. Willie, Stephen-Mark Cooper, Rob E. Shave> ;The Journal of Physiology. 2019 Feb 1
A multi-center evaluation of a disposable catheter to aid in correct positioning of the endotracheal tube after intubation in critically ill patients.
Avi Cohen, Laren Tan, Ramiz Fargo, James D Anholm, Chris Gasho, Kashif Yaqub, Sahil Chopra, Jennifer Hansen, Cynthia Huang, Dafne Moretta, Destry Washburn, H Bryant Ng...> ;Journal of Critical Care. 2018 Dec 1
19 citations
UBC-Nepal Expedition: An experimental overview of the 2016 University of British Columbia Scientific Expedition to Nepal Himalaya.
Christopher K. Willie, Mike Stembridge, Ryan L. Hoiland, Michael M. Tymko, Joshua C. Tremblay, Alexander Patrician, Craig D. Steinback, Jonathan P. Moore, James D. Anh...> ;Plos One. 2018 Oct 31
3 citations
Influence of myocardial oxygen demand on the coronary vascular response to arterial blood gas changes in humans.
Tyler D. Vermeulen, Lindsey M. Boulet, Mike Stembridge, Alexandra M. Williams, James D. Anholm, Prajan Subedi, Chris Gasho, Philip N. Ainslie, Eric O. Feigl, Glen E. F...> ;American Journal of Physiology. Heart and Circulatory Physiology. 2018 Mar 30
12 citations
One session of remote ischemic preconditioning does not improve vascular function in acute normobaric and chronic hypobaric hypoxia.
Mathew G. Rieger, Ryan L. Hoiland, Joshua C. Tremblay, Mike Stembridge, Anthony R. Bain, Daniela Flück, Prajan Subedi, James D. Anholm, Philip N. Ainslie> ;Experimental Physiology. 2017 Sep 1
18 citations
The effect of α1-adrenergic blockade on post-exercise brachial artery flow-mediated dilatation at sea level and high altitude
Michael M. Tymko, Joshua C. Tremblay, Alexander B. Hansen, Connor A. Howe, Chris K. Willie, Mike Stembridge, Daniel J. Green, Ryan L. Hoiland, Prajan Subedi, James D. ...> ;The Journal of Physiology. 2017 Mar 1
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Journal Articles

A Multi-Center Evaluation of a Disposable Catheter to Aid in Correct Positioning of the Endotracheal Tube After Intubation in Critically Ill Patients
James D Anholm, Destry Washburn, Laren Tan, Avi Cohen, Ramiz Fargo, ScienceDirect

Hospital Affiliations

Jerry L. Pettis Memorial Veterans' HospitalLoma Linda, California
Loma Linda University Medical CenterLoma Linda, California