JamesPatrickBridgesMD

PubMed

• 13 citations
  The expanding functional roles and signaling mechanisms of adhesion G protein-coupled receptors.
  Rory K. Morgan, Garret R. Anderson, Demet Araç, Gabriela Aust, Nariman Balenga, Antony A. Boucard, James P. Bridges, Felix B. Engel, Caroline J. Formstone, Maike D. Gl...> ;Annals of the New York Academy of Sciences. 2019 Nov 1
• 48 citations
  Statin as a novel pharmacotherapy of pulmonary alveolar proteinosis.
  Cormac McCarthy, Elinor Lee, James P. Bridges, Anthony Sallese, Takuji Suzuki, Jason C. Woods, Brian J. Bartholmai, Tisha Wang, Claudia Chalk, Brenna Carey, Paritha Ar...> ;Nature Communications. 2018 Aug 7
• 48 citations
  A Novel Triple-Mutant AAV6 Capsid Induces Rapid and Potent Transgene Expression in the Muscle and Respiratory Tract of Mice
  Laura P. van Lieshout, Jakob M. Domm, Tara N. Rindler, Kathy L. Frost, Debra L. Sorensen, Sarah J. Medina, Stephanie A. Booth, James P. Bridges, Sarah K. Wootton> ;Molecular Therapy. Methods & Clinical Development. 2018 Jun 15
• 26 citations
  Alveolar injury and regeneration following deletion of ABCA3
  Tara N. Rindler, Courtney A. Stockman, Alyssa Filuta, Kari M. Brown, John Snowball, Wenjia Zhou, Ruud A. W. Veldhuizen, Erika M. Zink, Sydney E. Dautel, Geremy Clair, ...> ;JCI Insight. 2017 Dec 21
• 32 citations
  Modeling pulmonary alveolar microlithiasis by epithelial deletion of the Npt2b sodium phosphate cotransporter reveals putative biomarkers and strategies for treatment
  Atsushi Saito, Nikolaos M. Nikolaidis, Hassane Amlal, Yasuaki Uehara, Jason D. Gardner, Kathleen LaSance, Lori B. Pitstick, James P. Bridges, Kathryn A. Wikenheiser-Br...> ;Science Translational Medicine. 2015 Nov 11
• 22 citations
  The M33 G Protein-Coupled Receptor Encoded by Murine Cytomegalovirus Is Dispensable for Hematogenous Dissemination but Is Required for Growth within the Salivary Gland
  Fabiola M. Bittencourt, Shu-En Wu, James P. Bridges, William E. Miller> ;Journal of Virology. 2014 Oct 15
• 13 citations
  Epithelial SCAP/INSIG/SREBP signaling regulates multiple biological processes during perinatal lung maturation.
  James P. Bridges, Angelica Schehr, Yanhua Wang, Liya Huo, Valérie Besnard, Machiko Ikegami, Jeffrey A. Whitsett, Yan Xu> ;Plos One. 2014 May 7
• 49 citations
  Orphan G Protein-Coupled Receptor GPR116 Regulates Pulmonary Surfactant Pool Size
  James P. Bridges, Marie-Gabrielle Ludwig, Matthias Mueller, Bernd Kinzel, Atsuyasu Sato, Yan Xu, Jeffrey A. Whitsett, Machiko Ikegami> ;American Journal of Respiratory Cell and Molecular Biology. 2013 Sep 1
• 27 citations
  Conditional hypoxia inducible factor-1α induction in embryonic pulmonary epithelium impairs maturation and augments lymphangiogenesis.
  James P. Bridges, Sui Lin, Machiko Ikegami, John M. Shannon> ;Developmental Biology. 2012 Feb 1
• 102 citations
  LPCAT1 regulates surfactant phospholipid synthesis and is required for transitioning to air breathing in mice
  James P. Bridges, Machiko Ikegami, Lauren L. Brilli, Xueni Chen, Robert J. Mason, John M. Shannon> ;The Journal of Clinical Investigation. 2010 May 3
• 9 citations
  Meckel-Gruber Syndrome Protein MKS3 Is Required for Endoplasmic Reticulum-associated Degradation of Surfactant Protein C
  Mei Wang, James P. Bridges, Cheng-Lun Na, Yan Xu, Timothy E. Weaver> ;The Journal of Biological Chemistry. 2009 Nov 27
• 113 citations
  Adenosine A2A receptor is a unique angiogenic target of HIF-2α in pulmonary endothelial cells
  Aftab Ahmad, Shama Ahmad, Louise E. Glover, Stacy M. Miller, John M. Shannon, Xiaoling Guo, Wilbur A. Franklin, James P. Bridges, Jerome Schaack, Sean P. Colgan, Carl ...> ;Proceedings of the National Academy of Sciences of the United States of America. 2009 Jun 30
• 128 citations
  ERdj4 and ERdj5 Are Required for Endoplasmic Reticulum-associated Protein Degradation of Misfolded Surfactant Protein C
  Mei Dong, James P. Bridges, Karen S. Apsley, Yan Xu, Timothy E. Weaver> ;Molecular Biology of the Cell. 2008 Jun 1
• 86 citations
  Adaptation and increased susceptibility to infection associated with constitutive expression of misfolded SP-C.
  James P. Bridges, Yan Xu, Cheng-Lun Na, Hector R. Wong, Timothy E. Weaver> ;The Journal of Cell Biology. 2006 Jan 30
• 9 citations
  Use of transgenic mice to study lung morphogenesis and function.
  James P. Bridges, Timothy E. Weaver> ;ILAR Journal. 2006 Jan 1
• 25 citations
  Surfactant lipid peroxidation damages surfactant protein A and inhibits interactions with phospholipid vesicles
  Alexander Kuzmenko, Huixing Wu, James P. Bridges, Francis X. McCormack> ;Journal of Lipid Research. 2004 Jun 1
• 108 citations
  Expression of a Human Surfactant Protein C Mutation Associated with Interstitial Lung Disease Disrupts Lung Development in Transgenic Mice
  James P. Bridges, Susan E. Wert, Lawrence M. Nogee, Timothy E. Weaver> ;The Journal of Biological Chemistry. 2003 Dec 26
• 43 citations
  Secretion of surfactant protein C, an integral membrane protein, requires the N-terminal propeptide.
  Juliana Conkright, James P. Bridges, Cheng-Lun Na, W. F. Voorhout, Bruce C. Trapnell, Stephan W. Glasser, Timothy E. Weaver> ;The Journal of Biological Chemistry. 2001 May 4
• 116 citations
  Pulmonary Surfactant Proteins A and D Are Potent Endogenous Inhibitors of Lipid Peroxidation and Oxidative Cellular Injury
  James P. Bridges, Harold W. Davis, Mamatha Damodarasamy, Yoshio Kuroki, Gabriel Howles, David Y. Hui, Francis X. McCormack> ;The Journal of Biological Chemistry. 2000 Dec 8
• 170 citations
  Interleukin-1 receptor antagonist treatment reduces pulmonary hypertension generated in rats by monocrotaline.
  Norbert F. Voelkel, Rubin M. Tuder, James P. Bridges, W P Arend> ;American Journal of Respiratory Cell and Molecular Biology. 1994 Dec 1
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