JamesKingsburyBrownMD

Pulmonology • San Francisco, CA

Critical Care Medicine, Pleural Disease

Professor, Medicine, UCSF School of Medicine

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Office
4150 Clement Street
VAMC 111D Building 203 Room 3a20
San Francisco, CA 94117
Phone+1 415-221-4810

Fax+1 415-387-3568
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Education & Training

University of California (San Francisco)Fellowship, Pulmonary Disease and Critical Care Medicine, 1976 - 1981
University of California (San Francisco)Residency, Internal Medicine, 1974 - 1976
Johns Hopkins UniversityInternship, Internal Medicine, 1972 - 1973
Johns Hopkins University School of MedicineClass of 1972

Certifications & Licensure

CA State Medical License 1975 - 2025
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Pulmonary Disease

Publications & Presentations

PubMed

1 citations
National Survey of Lung Cancer Screening Practices in Veterans Health Administration Facilities.
Eduardo R Núñez, Christopher G Slatore, Nichole T Tanner, Anne C Melzer, Kristina A Crothers, Jennifer A Lewis, Angela E Fabbrini, James K Brown, Renda S Wiener> ;American Journal of Preventive Medicine. 2023 Nov 1
Development and Validation of a Risk Assessment Model for Pulmonary Nodules Using Plasma Proteins and Clinical Factors.
Anil Vachani, Stephen Lam, Pierre P Massion, James K Brown, Michael Beggs, Amanda L Fish, Luis Carbonell, Shan X Wang, Peter J Mazzone> ;Chest. 2023 Apr 1
1 citations
Analytical validation of a novel multi-analyte plasma test for lung nodule characterization
Neil N. Trivedi, James K. Brown, Tess Rubenstein, Abigail D. Rostykus, Amanda L Fish, Heng Yu, Luis Carbonell, Alice Juang, Sandy Kamer, Bhavin Patel, Manpreet Sidhu, ...> ;Biomedical Research and Reviews. 2018 Nov 23
6 citations
Risk assessment for indeterminate pulmonary nodules using a novel, plasma-protein based biomarker assay.
Neil N. Trivedi, Mehrdad Arjomandi, James K. Brown, Tess Rubenstein, Abigail D. Rostykus, Stephanie Esposito, Eden Axler, Michael Beggs, Heng Yu, Luis Carbonell, Alice...> ;Biomedical Research and Clinical Practice. 2018 Oct 29
4 citations
Age, comorbidity, life expectancy, and pulmonary nodule follow-up in older veterans.
Melisa L. Wong, Ying Shi, Kathy Z. Fung, Sarah Ngo, Brett M. Elicker, James K. Brown, Robert A. Hiatt, Victoria L. Tang, Louise C. Walter> ;Plos One. 2018 Jul 25
4 citations
Bronchial hyperresponsiveness, word descriptors, and ethnicity: women with mild asthma.
Grace E. Hardie, James K. Brown, Warren M. Gold> ;The Journal of Asthma. 2012 Jan 12
8 citations
Adrenergic responsiveness: FEV1 and symptom differences in Whites and African Americans with mild asthma.
Grace E. Hardie, James K. Brown, Warren M. Gold> ;The Journal of Asthma. 2007 Oct 1
15 citations
Tryptase activates phosphatidylinositol 3-kinases proteolytically independently from proteinase-activated receptor-2 in cultured dog airway smooth muscle cells.
James K. Brown, Morley D. Hollenberg, Cary A. Jones> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2006 Feb 1
63 citations
Tryptase's potent mitogenic effects in human airway smooth muscle cells are via nonproteolytic actions
James K. Brown, Cary A. Jones, Leeann A. Rooney, George H. Caughey, Ian P. Hall> ;American Journal of Physiology. Lung Cellular and Molecular Physiology. 2002 Feb 1
16 citations
Mast cell tryptase activates extracellular-regulated kinases (p44/p42) in airway smooth-muscle cells: importance of proteolytic events, time course, and role in mediat...
James K. Brown, Cary A. Jones, Leeann A. Rooney, George H. Caughey> ;American Journal of Respiratory Cell and Molecular Biology. 2001 Feb 1
47 citations
Buprenorphine and Naloxone Interactions in Methadone Maintenance Patients
John Mendelson, Reese T. Jones, Susette Welm, James K. Brown, Steven L. Batki> ;Biological Psychiatry. 1997 Jun 1
34 citations
Tryptase-Induced Mitogenesis in Airway Smooth Muscle Cells: Potency, Mechanisms, and Interactions With Other Mast Cell Mediators
James K. Brown, Cary A. Jones, Christopher L. Tyler, Stephen J. Ruoss, Thomas E. Hartmann, George H. Caughey> ;Chest. 1995 Mar 1
116 citations
Oxygen may improve dyspnea and endurance in patients with chronic obstructive pulmonary disease and only mild hypoxemia.
Nathan C. Dean, James K. Brown, Ronald B. Himelman, Joseph J. Doherty, Warren M. Gold, Michael S. Stulbarg> ;The American Review of Respiratory Disease. 1992 Oct 1
6 citations
Receptors on airway gland cells.
Carol Basbaum, J. M. Madison, Christian P. Sommerhoff, J. K. Brown, Walter E. Finkbeiner> ;The American Review of Respiratory Disease. 1990 Mar 1
7 citations
Differential effects of prostaglandin E2 on contractions of airway smooth muscle.
J. M. Madison, C. A. Jones, R. M. Sankary, J. K. Brown> ;Journal of Applied Physiology. 1989 Mar 1
5 citations
Characterization of beta-adrenergic receptors in cultured bovine tracheal gland cells.
J. M. Madison, C. B. Basbaum, J. K. Brown, Walter E. Finkbeiner> ;The American Journal of Physiology. 1989 Feb 1
1 citations
Status asthmaticus: Early institution of treatment
Nathan C. Dean, James K. Brown> ;Postgraduate Medicine. 1988 Sep 15
69 citations
Muscarinic cholinergic inhibition of cyclic AMP accumulation in airway smooth muscle. Role of a pertussis toxin-sensitive protein.
R. M. Sankary, C. A. Jones, Madison Jm, J. K. Brown> ;The American Review of Respiratory Disease. 1988 Jul 1
44 citations
Improved recognition of cor pulmonale in patients with severe chronic obstructive pulmonary disease
Ronald B. Himelman, Steven N. Struve, James K. Brown, Peter Namnum, Nelson B. Schiller> ;The American Journal of Medicine. 1988 May 1
32 citations
Morphologic characterization of cultured smooth muscle cells isolated from the tracheas of adult dogs
M. Tom-Moy, J. M. Madison, C. A. Jones, P. de Lanerolle, J. K. Brown> ;The Anatomical Record. 1987 Jul 1
96 citations
Muscarinic cholinergic inhibition of adenylate cyclase in airway smooth muscle.
C. A. Jones, Madison Jm, M. Tom-Moy, J. K. Brown> ;The American Journal of Physiology. 1987 Jul 1
18 citations
Affinities of pirenzepine for muscarinic cholinergic receptors in membranes isolated from bovine tracheal mucosa and smooth muscle.
Madison Jm, C. A. Jones, M. Tom-Moy, J. K. Brown> ;The American Review of Respiratory Disease. 1987 Mar 1
7 citations
Immunologic release of histamine from dog lung: comparison of in vivo and in vitro responses in the same animal.
Martin J. Frey, Sarah E. Chesrown, Baron R. Reed, Lee W. Greenspon, Robert L. Shields, Henry R. Bourne, James K. Brown, Warren M. Gold> ;The Journal of Allergy and Clinical Immunology. 1984 Nov 1
2 citations
Radioenzymatic assay for measurement of tissue concentrations of histamine: adaptation to correct for adherence of histamine to mechanical homogenizers.
James K. Brown, Martin J. Frey, Baron R. Reed, Alan R. Leff, Robert L. Shields, Warren M. Gold> ;The Journal of Allergy and Clinical Immunology. 1984 Apr 1
8 citations
Augmentation of alpha-adrenergic contractions in the trachealis muscle of living dogs.
James K. Brown, R. Shields, C. Jones, Warren M. Gold> ;Journal of Applied Physiology. 1983 Jun 1
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Hospital Affiliations

San Francisco VA Medical CenterSan Francisco, California