JamesC.M.BrustMD

PubMed

• Differentiated service delivery framework for people with multidrug-resistant tuberculosis and HIV co-infection.
  Karl Reis, Allison Wolf, Rubeshan Perumal, Boitumelo Seepamore, Kevin Guzman, Jesse Ross, Ken Cheung, K Rivet Amico, James C M Brust, Nesri Padayatchi, Gerald Friedlan...> ;Journal of Acquired Immune Deficiency Syndromes. 2024 Feb 6
• 5 citations
  Pharmacogenetics of Between-Individual Variability in Plasma Clearance of Bedaquiline and Clofazimine in South Africa.
  David W Haas, Mahmoud Tareq Abdelwahab, Stijn W van Beek, Paxton Baker, Gary Maartens, Yuki Bradford, Marylyn D Ritchie, Sean Wasserman, Graeme Meintjes, Karen Beeri, ...> ;The Journal of Infectious Diseases. 2022 Aug 12
• 1 citations
  Model-Predicted Impact of ECG Monitoring Strategies During Bedaquiline Treatment.
  Stijn W van Beek, Lénaïg Tanneau, Graeme Meintjes, Sean Wasserman, Neel R Gandhi, Angie Campbell, Charle A Viljoen, Lubbe Wiesner, Rob E Aarnoutse, Gary Maartens, Jame...> ;Open Forum Infectious Diseases. 2022 Aug 1
• 3 citations
  Linezolid toxicity in patients with drug-resistant tuberculosis: a prospective cohort study.
  Sean Wasserman, James C M Brust, Mahmoud T Abdelwahab, Francesca Little, Paolo Denti, Lubbe Wiesner, Neel R Gandhi, Graeme Meintjes, Gary Maartens> ;The Journal of Antimicrobial Chemotherapy. 2022 Mar 31
• 6 citations
  Adherence Measured Using Electronic Dose Monitoring is Associated with Emergent Antiretroviral Resistance and Poor Outcomes in People with Human Immunodeficiency Virus...
  Mark Bateman, Allison Wolf, Benjamin Chimukangara, James C M Brust, Richard Lessells, Rivet Amico, Resha Boodhram, Nalini Singh, Catherine Orrell, Gerald Friedland, Ko...> ;Clinical Infectious Diseases. 2022 Oct 29
• Optimized Loading Dose Strategies for Bedaquiline When Restarting Interrupted Drug-Resistant Tuberculosis Treatment.
  Simon E Koele, Stijn W van Beek, Gary Maartens, James C M Brust, Elin M Svensson> ;Antimicrobial Agents and Chemotherapy. 2022 Mar 15
• 21 citations
  TCA cycle remodeling drives proinflammatory signaling in humans with pulmonary tuberculosis.
  Jeffrey M. Collins, Dean P. Jones, Manoj Khadka, Ken H. Liu, Russell R. Kempker, Brendan Prideaux, Kristal M. Maner-Smith, Nestani Tukvadze, N Sarita Shah, James C.M. ...> ;Plos Pathogens. 2021 Sep 24
• 8 citations
  Linezolid Population Pharmacokinetics in South African Adults with Drug-Resistant Tuberculosis.
  Mahmoud Tareq Abdelwahab, Sean Wasserman, James C.M. Brust, Keertan Dheda, Lubbe Wiesner, Neel R. Gandhi, Robin M. Warren, Frederick A. Sirgel, Graeme Meintjes, Gary M...> ;Antimicrobial Agents and Chemotherapy. 2021 Sep 20
• 14 citations
  Evidence-based Definition for Extensively Drug-Resistant Tuberculosis.
  Maroussia Roelens, Giovanni Battista Migliori, Liudmila Rozanova, Janne Estill, Jonathon R. Campbell, J. Peter Cegielski, Simon Tiberi, Domingo Palmero, Greg J. Fox, L...> ;American Journal of Respiratory and Critical Care Medicine. 2021 Sep 15
• 6 citations
  Relationship between Plasma and Intracellular Concentrations of Bedaquiline and Its M2 Metabolite in South African Patients with Rifampin-Resistant Tuberculosis.
  Precious Ngwalero, James C.M. Brust, Stijn W van Beek, Sean Wasserman, Gary Maartens, Graeme Meintjes, Anton Joubert, Jennifer Norman, Sandra Castel, Neel R. Gandhi, P...> ;Antimicrobial Agents and Chemotherapy. 2021 Aug 9
• 17 citations
  Effectiveness and cardiac safety of bedaquiline-based therapy for drug-resistant tuberculosis: a prospective cohort study.
  James C.M. Brust, Neel R. Gandhi, Sean Wasserman, Gary Maartens, Shaheed Omar, Nazir Ahmed Ismail, Angela Campbell, Lindsay Joseph, Alexandria L Hahn, Salim Allana, Al...> ;Clinical Infectious Diseases. 2021 Apr 21
• 29 citations
  Clofazimine pharmacokinetics in patients with TB: dosing implications
  Mahmoud Tareq Abdelwahab, Sean Wasserman, James C.M. Brust, Neel R. Gandhi, Graeme Meintjes, Daniel Everitt, Andreas H. Diacon, Rodney Dawson, Lubbe Wiesner, Elin M. S...> ;The Journal of Antimicrobial Chemotherapy. 2020 Nov 1
• 13 citations
  Treatment outcomes in patients with drug-resistant TB-HIV co-infection treated with bedaquiline and linezolid.
  Nesri Padayatchi, N Bionghi, F Osman, Naressa Naidu, Norbert Ndjeka, Iqbal Master, James C.M. Brust, K Naidoo, A. Ramjee, M O Donnell> ;The International Journal of Tuberculosis and Lung Disease. 2020 Oct 1
• 41 citations
  Mortality in adults with multidrug-resistant tuberculosis and HIV by antiretroviral therapy and tuberculosis drug use: an individual patient data meta-analysis.
  Gregory P. Bisson, Mayara Lisboa Bastos, Jonathon R. Campbell, Didi Bang, James C.M. Brust, Petros Isaakidis, Christoph Lange, Dick Menzies, Giovanni Battista Migliori...> ;Lancet. 2020 Aug 8
• 3 citations
  Modeling missing cases and transmission links in networks of extensively drug-resistant tuberculosis in KwaZulu-Natal, South Africa
  Kristin N. Nelson, Neel R. Gandhi, Barun Mathema, Benjamin A. Lopman, James C.M. Brust, Sara C. Auld, Nazir Ahmed Ismail, Shaheed V. Omar, Tyler S. Brown, Salim Allana...> ;American Journal of Epidemiology. 2020 Jul 1
• 4 citations
  Social mixing and clinical features linked with transmission in a network of extensively drug-resistant tuberculosis cases in KwaZulu-Natal, South Africa
  Kristin N. Nelson, Samuel M. Jenness, Barun Mathema, Benjamin A. Lopman, Sara C. Auld, N. Sarita Shah, James C.M. Brust, Nazir Ahmed Ismail, Shaheed V. Omar, Tyler S. ...> ;Clinical Infectious Diseases. 2020 May 23
• 42 citations
  Tryptophan catabolism reflects disease activity in human tuberculosis
  Jeffrey M. Collins, Amnah Siddiqa, Dean P. Jones, Ken Liu, Russell R. Kempker, Azhar Nizam, N Sarita Shah, Nazir Ahmed Ismail, Samuel Gurrion Ouma, Nestani Tukvadze, S...> ;JCI Insight. 2020 May 21
• 118 citations
  Drug-associated adverse events in the treatment of multidrug-resistant tuberculosis: an individual patient data meta-analysis.
  Zhiyi Lan, Nafees Ahmad, Parvaneh Baghaei, Linda Barkane, Andrea Benedetti, Sarah K. Brode, James C.M. Brust, Jonathon R. Campbell, Vicky Chang, Dennis Falzon, Lorenzo...> ;The Lancet. Respiratory Medicine. 2020 Mar 17
• 7 citations
  The Impact of Concurrent Antiretroviral Therapy and MDR-TB Treatment on Adverse Events.
  Jonathan P. Smith, Neel R. Gandhi, N. Sarita Shah, Koleka Mlisana, Pravi Moodley, Brent A. Johnson, Salim Allana, Angela Campbell, Kristin N. Nelson, Iqbal Master, Jam...> ;Journal of Acquired Immune Deficiency Syndromes. 2020 Jan 1
• 18 citations
  Pre-detection history of extensively drug-resistant tuberculosis in KwaZulu-Natal, South Africa.
  Tyler S. Brown, Lavanya Challagundla, Evan H. Baugh, Shaheed V. Omar, Arkady Mustaev, Sara C. Auld, N. Sarita Shah, Barry N. Kreiswirth, James C.M. Brust, Kristin N. N...> ;Proceedings of the National Academy of Sciences of the United States of America. 2019 Nov 12
• 6 citations
  Treatment Adherence Among Persons Receiving Concurrent Multidrug-Resistant Tuberculosis and HIV Treatment in KwaZulu-Natal, South Africa.
  Fay Stephens, Neel R. Gandhi, James C.M. Brust, Koleka Mlisana, Pravi Moodley, Salim Allana, Angie Campbell, Sarita Shah> ;Journal of Acquired Immune Deficiency Syndromes. 2019 Oct 1
• 25 citations
  Management of active tuberculosis in adults with HIV.
  Graeme Meintjes, James C.M. Brust, James Nuttall, Gary Maartens> ;The Lancet. HIV. 2019 Jul 1
• 11 citations
  Extensively drug-resistant tuberculosis 'hotspots' and sociodemographic associations in Durban, South Africa.
  M L Peterson, Neel R. Gandhi, Julie A. Clennon, Kristin N. Nelson, Natashia Morris, Nazir Ahmed Ismail, Salim Allana, Angie Campbell, James C.M. Brust, Sara C. Auld, B...> ;The International Journal of Tuberculosis and Lung Disease. 2019 Jun 1
• 15 citations
  rpoB Mutations Causing Discordant Rifampicin Susceptibility in Mycobacterium tuberculosis: Retrospective Analysis of Prevalence, Phenotypic, Genotypic, and Treatment O...
  Nomonde R. Mvelase, Melendhran Pillay, Wilbert Sibanda, Jacqueline. Ngozo, James C.M. Brust, Koleka Mlisana> ;Open Forum Infectious Diseases. 2019 Feb 12
• 16 citations
  Linezolid Pharmacokinetics in South African Patients with Drug-Resistant Tuberculosis and a High Prevalence of HIV Coinfection.
  Sean Wasserman, Paolo Denti, James C.M. Brust, Mahmoud Tareq Abdelwahab, Siphokazi Hlungulu, Lubbe Wiesner, Jennifer Norman, Frederick A. Sirgel, Robin M. Warren, Alia...> ;Antimicrobial Agents and Chemotherapy. 2019 Feb 26
• Join now to see all