JamesLinChenMD

PubMed

• ASO Visual Abstract: Adjuvant Palbociclib May be Associated with Delayed Recurrence in Completely Resected Retroperitoneal Liposarcoma: Results of a Single-Institution...
  Clark, E., Tinoco, G., Bashian, E., Tinoco Suarez, G. R., Tinoco Suarez, G. R., Selby, L., Liebner, D., Chen, J., Beane, J., Pollock, R., Grignol, V., Tinoco Suarez, G...> ;Annals of Surgical Oncology. 2024 Apr 1
• The T Cell Immunoscore as a Reference for Biomarker Development Utilizing Real-World Data from Patients with Advanced Malignancies Treated with Immune Checkpoint Inhib...
  Islam Eljilany, Payman Ghasemi Saghand, James Chen, Aakrosh Ratan, Martin McCarter, John Carpten, Howard Colman, Alexandra P Ikeguchi, Igor Puzanov, Susanne Arnold, Mi...> ;Cancers. 2023 Oct 10
• 1 citations
  Gene partners of the EWSR1 fusion may represent molecularly distinct entities.
  Victoria Walker, Dexter X Jin, Sherri Z Millis, Elham Nasri, Diana A Corao-Uribe, Aik Choon Tan, Brooke L Fridley, James L Chen, Nathan D Seligson> ;Translational Oncology. 2023 Dec 1
• 1 citations
  Adjuvant Palbociclib May be Associated with Delayed Recurrence in Completely Resected Retroperitoneal Liposarcoma: Results of a Single-Institution Retrospective Cohort...
  Luke V Selby, Emma C Clark, David A Liebner, James L Chen, Gabriel Tinoco, Elizabeth Bashian, Joal D Beane, Raphael E Pollock, Valerie P Grignol, Tinoco Suarez, G. R.> ;Annals of Surgical Oncology. 2023 Nov 1
• 4 citations
  Clinical markers of immunotherapy outcomes in advanced sarcoma.
  Marium Husain, Dionisia Quiroga, Han Gil Kim, Scott Lenobel, Menglin Xu, Hans Iwenofu, James L Chen, Claire Verschraegen, David Liebner, Gabriel Tinoco> ;BMC Cancer. 2023 Apr 7
• 14 citations
  Selinexor in Advanced, Metastatic Dedifferentiated Liposarcoma: A Multinational, Randomized, Double-Blind, Placebo-Controlled Trial.
  Mrinal M Gounder, Albiruni Abdul Razak, Neeta Somaiah, Sant Chawla, Javier Martin-Broto, Giovanni Grignani, Scott M Schuetze, Bruno Vincenzi, Andrew J Wagner, Bartosz ...> ;Journal of Clinical Oncology. 2022 Aug 1
• 5 citations
  Drivers of genomic loss of heterozygosity in leiomyosarcoma are distinct from carcinomas.
  Nathan D Seligson, Joy Tang, Dexter X Jin, Monica P Bennett, Julia A Elvin, Kiley Graim, John L Hays, Sherri Z Millis, Wayne O Miles, James L Chen> ;NPJ Precision Oncology. 2022 Apr 25
• 1 citations
  Quantitating and assessing interoperability between electronic health records.
  Elmer V Bernstam, Jeremy L Warner, John C Krauss, Edward Ambinder, Wendy S Rubinstein, George Komatsoulis, Robert S Miller, James L Chen> ;Journal of the American Medical Informatics Association. 2022 Apr 13
• Challenges and Gaps in Clinical Trial Genomic Data Management.
  Sarah Asad, Kathryn Kananen, Kurt R Mueller, W Fraser Symmans, Yujia Wen, Charles M Perou, James S Blachly, James Chen, Benjamin G Vincent, Daniel G Stover> ;JCO Clinical Cancer Informatics. 2022 Mar 1
• 16 citations
  Clinical Utility of CDK4/6 Inhibitors in Sarcoma: Successes and Future Challenges.
  Jocelyn Y Hsu, Nathan D Seligson, John L Hays, Wayne O Miles, James L Chen> ;JCO Precision Oncology. 2022 Feb 1
• 7 citations
  Chasm Between Cancer Quality Measures and Electronic Health Record Data Quality.
  Anna E Schorer, Richard Moldwin, Jacob Koskimaki, Elmer V Bernstam, Neeta K Venepalli, Robert S Miller, James L Chen> ;JCO Clinical Cancer Informatics. 2022 Jan 1
• 1 citations
  Randomized Prospective Trial Exploring the Impact of Structured Journaling in Patients With Sarcoma on the Management of Treatment-Related Adverse Events.
  N J Speece, Menglin Xu, Gabriel Tinoco, David A. Liebner, James L. Chen> ;JCO Oncology Practice. 2021 Sep 24
• 12 citations
  Multiscale-omic assessment of EWSR1-NFATc2 fusion positive sarcomas identifies the mTOR pathway as a potential therapeutic target.
  Nathan D. Seligson, Richard D Maradiaga, Colin M Stets, Howard M. Katzenstein, Sherri Z. Millis, Alan Rogers, John L. Hays, James L. Chen> ;NPJ Precision Oncology. 2021 May 21
• 1 citations
  Modern multimodality management of patients with caval leiomyosarcoma: New treatment paradigms and potential molecular insights.
  Malcolm H. Squires, Stephen Politano, Raphael E. Pollock, James L. Chen, Valerie P. Grignol> ;Journal of Surgical Oncology. 2021 Mar 2
• Compression induced hepatic injury: an unusual case of abnormal liver function tests.
  Lindsay A. Sobotka, James L. Chen, Michael Wellner> ;Clinics and Research in Hepatology and Gastroenterology. 2021 Feb 23
• 22 citations
  A Systematic Framework to Rapidly Obtain Data on Patients with Cancer and COVID-19: CCC19 Governance, Protocol, and Quality Assurance.
  , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , ,...> ;Cancer Cell. 2020 Dec 14
• 14 citations
  Recommendations for patient similarity classes: results of the AMIA 2019 workshop on defining patient similarity.
  Nathan D. Seligson, Jeremy L. Warner, William S. Dalton, David Martin, Robert S. Miller, Debra A. Patt, Kenneth L. Kehl, Matvey B. Palchuk, Gil Alterovitz, Laura K. Wi...> ;Journal of the American Medical Informatics Association. 2020 Nov 1
• 7 citations
  MDM2-Dependent Rewiring of Metabolomic and Lipidomic Profiles in Dedifferentiated Liposarcoma Models
  Andrew Patt, Bryce Demoret, Colin W. Stets, Kate Lynn J. Bill, Philip B. Smith, Anitha Vijay, Andrew D. Patterson, John L. Hays, Mindy Hoang, James L. Chen, Ewy Mathé> ;Cancers. 2020 Aug 4
• 19 citations
  Collaborative, Multidisciplinary Evaluation of Cancer Variants Through Virtual Molecular Tumor Boards Informs Local Clinical Practices.
  Shruti Rao, Beth A. Pitel, Alex H. Wagner, Simina M. Boca, Matthew McCoy, Ian F. G. King, Samir Gupta, Ben Ho Park, Jeremy L. Warner, James L. Chen, Peter K. Rogan, De...> ;JCO Clinical Cancer Informatics. 2020 Jul 9
• 1183 citations
  Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study.
  Nicole M. Kuderer, Toni K. Choueiri, Dimpy P. Shah, Yu Shyr, Samuel M. Rubinstein, Donna R. Rivera, Sanjay Shete, Chih-Yuan Hsu, Aakash Desai, Gilberto Lopes, Petros G...> ;Lancet. 2020 Jun 20
• 15 citations
  Activity of PD1 inhibitor therapy in advanced sarcoma: a single-center retrospective analysis
  Dionisia Quiroga, David A. Liebner, Jennifer Philippon, Sarah Hoffman, Yubo Tan, James L. Chen, Scott Lenobel, Paul E. Wakely, Raphael E. Pollock, Gabriel Tinoco> ;BMC Cancer. 2020 Jun 5
• 8 citations
  Metastatic breast cancer patient perceptions of somatic tumor genomic testing
  Elizabeth J. Adams, Sarah Asad, Raquel E. Reinbolt, Katharine Collier, Mahmoud Abdel-Rasoul, Susan Gillespie, James L. Chen, Mathew Cherian, Anne M. Noonan, Sagar Sard...> ;BMC Cancer. 2020 May 6
• 9 citations
  Identifying Opportunities and Challenges for Patients With Sarcoma as a Result of Comprehensive Genomic Profiling of Sarcoma Specimens.
  Margaret A Hay, Eric Allan Severson, Vincent A. Miller, David A. Liebner, Jo-Anne Vergilio, Sherri Z. Millis, James L. Chen> ;JCO Precision Oncology. 2020 Mar 18
• 9 citations
  Prospective Evaluation of the Concordance of Commercial Circulating Tumor DNA Alterations with Tumor-Based Sequencing across Multiple Soft Tissue Sarcoma Subtypes.
  Bryce Demoret, Jeffrey P. Gregg, David A. Liebner, Gabriel Tinoco, Scott Lenobel, James L. Chen> ;Cancers. 2019 Nov 21
• 9 citations
  Prospective Decision Analysis Study of Clinical Genomic Testing in Metastatic Breast Cancer: Impact on Outcomes and Patient Perceptions.
  Daniel G. Stover, Raquel E. Reinbolt, Elizabeth J. Adams, Sarah Asad, Katlyn Tolliver, Mahmoud Abdel-Rasoul, Cynthia Timmers, Susan Gillespie, James L. Chen, Siraj M. ...> ;JCO Precision Oncology. 2019 Nov 18
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Journal Articles

• The Omics Revolution Continues: The Maturation of High-Throughput Biological Data Sources  
  James L Chen, John L Hays, Yearbook of Medical Informatics
• Loss of TXNIP Enhances Peritoneal Metastasis and Can Be Abrogated by Dual TORC1/2 Inhibition  
  David Cohen, James L Chen, John L Hays, Oncotarget

Abstracts/Posters

• An All Antibody Approach for Conditioning Bone Marrow for Hematopoietic Stem Cell Transplantation with Anti-cKIT and Anti-CD47 in Non-Human Primates
  James Y Chen, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019

Lectures

• Deriving real-world oral antineoplastic treatment endpoints: A comparison of automated data extraction versus manual chart abstraction. 
  2019 ASCO Annual Meeting - 6/1/2019